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17 Results  for Everything (Includes Articles)

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The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma

Ehara, Takeru ; Adams, Christopher M ; Bevan, Doug ; Ji, Nan ; Meredith, Erik L ; Belanger, David B ; Powers, James ; Kato, Mitsunori ; Solovay, Catherine ; Liu, Donglei ; Capparelli, Michael ; Bolduc, Philippe ; Grob, Jonathan E ; Daniels, Matthew H ; Ferrara, Luciana ; Yang, Louis ; Li, Byron ; Towler, Christopher S ; Stacy, Rebecca C ; Prasanna, Ganesh ; Mogi, Muneto

Journal of medicinal chemistry, 22 March 2018, Vol.61(6), pp.2552-2570 [Peer Reviewed Journal]

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Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid

Andrus, Merritt B ; Liu, Jing ; Meredith, Erik L ; Nartey, Edward

Tetrahedron Letters, 2003, Vol.44(26), pp.4819-4822 [Peer Reviewed Journal]

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The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration

Adams, Christopher M ; Anderson, Karen ; Artman, Gerald ; Bizec, Jean-Claude ; Cepeda, Rosemarie ; Elliott, Jason ; Fassbender, Elizabeth ; Ghosh, Malay ; Hanks, Shawn ; Hardegger, Leo A ; Hosagrahara, Vinayak P ; Jaffee, Bruce ; Jendza, Keith ; Ji, Nan ; Johnson, Leland ; Lee, Wendy ; Liu, Donglei ; Liu, Fang ; Long, Debby ; Ma, Fupeng ; Mainolfi, Nello ; Meredith, Erik L ; Miranda, Karl ; Peng, Yao ; Poor, Stephen ; Powers, James ; Qiu, Yubin ; Rao, Chang ; Shen, Siyuan ; Sivak, Jeremy M ; Solovay, Catherine ; Tarsa, Peter ; Woolfenden, Amber ; Zhang, Chun ; Zhang, Yiqin

Journal of medicinal chemistry, 22 February 2018, Vol.61(4), pp.1622-1635 [Peer Reviewed Journal]

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Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration

Meredith, Erik L ; Mainolfi, Nello ; Poor, Stephen ; Qiu, Yubin ; Miranda, Karl ; Powers, James ; Liu, Donglei ; Ma, Fupeng ; Solovay, Catherine ; Rao, Chang ; Johnson, Leland ; Ji, Nan ; Artman, Gerald ; Hardegger, Leo ; Hanks, Shawn ; Shen, Siyuan ; Woolfenden, Amber ; Fassbender, Elizabeth ; Sivak, Jeremy M ; Zhang, Yiqin ; Long, Debby ; Cepeda, Rosemarie ; Liu, Fang ; Hosagrahara, Vinayak P ; Lee, Wendy ; Tarsa, Peter ; Anderson, Karen ; Elliott, Jason ; Jaffee, Bruce

Journal of medicinal chemistry, 10 December 2015, Vol.58(23), pp.9273-86 [Peer Reviewed Journal]

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Highly selective syn glycolate aldol reactions with boron enolates of Masamune norephedrine esters

Andrus, Merritt B ; Soma Sekhar, B.B.V ; Turner, Timothy M ; Meredith, Erik L

Tetrahedron Letters, 08 October 2001, Vol.42(41), pp.7197-7201 [Peer Reviewed Journal]

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Glycolate aldol reactions with boron enolates of bis-4-methoxyphenyl dioxanone

Andrus, Merritt B ; Mendenhall, Kris G ; Meredith, Erik L ; Soma Sekhar, B.B.V

Tetrahedron Letters, 04 March 2002, Vol.43(10), pp.1789-1792 [Peer Reviewed Journal]

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Synthesis of the Left-Hand Portion of Geldanamycin Using an Anti Glycolate Aldol Reaction
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Synthesis of the Left-Hand Portion of Geldanamycin Using an Anti Glycolate Aldol Reaction

Andrus, Merritt B. ; Meredith, Erik L. ; Sekhar, B. B. V. Soma

Organic Letters, 01/2001, Vol.3(2), pp.259-262 [Peer Reviewed Journal]

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Design and Synthesis of Potent Sensitizers of Gram-Negative Bacteria Based on a Cholic Acid Scaffolding
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Design and Synthesis of Potent Sensitizers of Gram-Negative Bacteria Based on a Cholic Acid Scaffolding

Li, Chunhong ; Peters, Adam S. ; Meredith, Erik L. ; Allman, Glenn W. ; Savage, Paul B.

Journal of the American Chemical Society, 04/1998, Vol.120(12), pp.2961-2962 [Peer Reviewed Journal]

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Identification of potent and selective amidobipyridyl inhibitors of protein kinase D

Meredith, Erik L ; Beattie, Kimberly ; Burgis, Robin ; Capparelli, Michael ; Chapo, Joseph ; Dipietro, Lucian ; Gamber, Gabriel ; Enyedy, Istvan ; Hood, David B ; Hosagrahara, Vinayak ; Jewell, Charles ; Koch, Keith A ; Lee, Wendy ; Lemon, Douglas D ; Mckinsey, Timothy A ; Miranda, Karl ; Pagratis, Nikos ; Phan, Dillon ; Plato, Craig ; Rao, Chang ; Rozhitskaya, Olga ; Soldermann, Nicolas ; Springer, Clayton ; Van Eis, Maurice ; Vega, Richard B ; Yan, Wanlin ; Zhu, Qingming ; Monovich, Lauren G

Journal of medicinal chemistry, 12 August 2010, Vol.53(15), pp.5422-38 [Peer Reviewed Journal]

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Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin: asymmetric glycolate aldol reactions and biological evaluation

Andrus, Merritt B ; Meredith, Erik L ; Hicken, Erik J ; Simmons, Bryon L ; Glancey, Russell R ; Ma, Wei

The Journal of organic chemistry, 17 October 2003, Vol.68(21), pp.8162-9 [Peer Reviewed Journal]

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Selective synthesis of the para-quinone region of geldanamycin

Andrus, Merritt B ; Hicken, Erik J ; Meredith, Erik L ; Simmons, Bryon L ; Cannon, John F

Organic letters, 16 October 2003, Vol.5(21), pp.3859-62 [Peer Reviewed Journal]

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Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions

Andrus, Merritt B ; Meredith, Erik L ; Simmons, Bryon L ; Soma Sekhar, B B V ; Hicken, Erik J

Organic letters, 03 October 2002, Vol.4(20), pp.3549-52 [Peer Reviewed Journal]

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Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation

Poor, Stephen H ; Qiu, Yubin ; Fassbender, Elizabeth S ; Shen, Siyuan ; Woolfenden, Amber ; Delpero, Andrea ; Kim, Yong ; Buchanan, Natasha ; Gebuhr, Thomas C ; Hanks, Shawn M ; Meredith, Erik L ; Jaffee, Bruce D ; Dryja, Thaddeus P

Investigative ophthalmology & visual science, 09 September 2014, Vol.55(10), pp.6525-34 [Peer Reviewed Journal]

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Anti -Selective Glycolate Aldol Additions with an Oxapyrone Boron Enolate
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Anti -Selective Glycolate Aldol Additions with an Oxapyrone Boron Enolate

Andrus, Merritt B. ; Sekhar, B. B. V. Soma ; Meredith, Erik L. ; Dalley, N. Kent

Organic Letters, 09/2000, Vol.2(19), pp.3035-3037 [Peer Reviewed Journal]

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Identification of orally available naphthyridine protein kinase D inhibitors

Meredith, Erik L ; Ardayfio, Ophelia ; Beattie, Kimberly ; Dobler, Markus R ; Enyedy, Istvan ; Gaul, Christoph ; Hosagrahara, Vinayak ; Jewell, Charles ; Koch, Keith ; Lee, Wendy ; Lehmann, Hansjoerg ; Mckinsey, Timothy A ; Miranda, Karl ; Pagratis, Nikos ; Pancost, Margaret ; Patnaik, Anup ; Phan, Dillon ; Plato, Craig ; Qian, Ming ; Rajaraman, Vasumathy ; Rao, Chang ; Rozhitskaya, Olga ; Ruppen, Thomas ; Shi, Jie ; Siska, Sarah J ; Springer, Clayton ; Van Eis, Maurice ; Vega, Richard B ; Von Matt, Anette ; Yang, Lihua ; Yoon, Taeyoung ; Zhang, Ji-Hu ; Zhu, Na ; Monovich, Lauren G

Journal of medicinal chemistry, 12 August 2010, Vol.53(15), pp.5400-21 [Peer Reviewed Journal]

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Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors

Meredith, Erik L ; Ksander, Gary ; Monovich, Lauren G ; Papillon, Julien P N ; Liu, Qian ; Miranda, Karl ; Morris, Patrick ; Rao, Chang ; Burgis, Robin ; Capparelli, Michael ; Hu, Qi-Ying ; Singh, Alok ; Rigel, Dean F ; Jeng, Arco Y ; Beil, Michael ; Fu, Fumin ; Hu, Chii-Whei ; Lasala, Daniel

ACS medicinal chemistry letters, 12 December 2013, Vol.4(12), pp.1203-7 [Peer Reviewed Journal]

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CCDC 1814475: Experimental Crystal Structure Determination

Ehara, Takeru ; Adams, Christopher M. ; Bevan, Doug ; Ji, Nan ; Meredith, Erik L. ; Belanger, David B. ; Powers, James ; Kato, Mitsunori ; Solovay, Catherine ; Liu, Donglei ; Capparelli, Michael ; Bolduc, Philippe ; Grob, Jonathan E. ; Daniels, Matthew H. ; Ferrara, Luciana ; Yang, Louis ; Li, Byron ; Towler, Christopher S. ; Stacy, Rebecca C. ; Prasanna, Ganesh ; Mogi, Muneto

2018

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