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Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

Amador, Ariadna ; Wang, Yongjun ; Banerjee, Subhashis ; Kamenecka, Theodore M ; Solt, Laura A ; Burris, Thomas P

PLoS ONE, 2016, Vol.11(5) [Peer Reviewed Journal]

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Synthesis of 2-aryl-2H-tetrazoles via a regioselective [3+2] cycloaddition reaction

Patouret, Remi ; Kamenecka, Theodore M

Tetrahedron Letters, 06 April 2016, Vol.57(14), pp.1597-1599 [Peer Reviewed Journal]

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Multigram-scale synthesis of enantiopure 3,3-difluoroproline

Doebelin, Christelle ; He, Yuanjun ; Kamenecka, Theodore M

Tetrahedron Letters, 14 December 2016, Vol.57(50), pp.5658-5660 [Peer Reviewed Journal]

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LXR-Mediated Inhibition of CD4 + T Helper Cells (LXR/ROR Regulation of T Cell Function)

Solt, Laura A ; Kamenecka, Theodore M ; Burris, Thomas P Cooney, Austin John (Editor)

2012, Vol.7(9), p.e46615 [Peer Reviewed Journal]

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5
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Site‐Selective γ‐C(sp3)−H and γ‐C(sp2)−H Arylation of Free Amino Esters Promoted by a Catalytic Transient Directing Group

Lin, Hua ; Wang, Chao ; Bannister, Thomas D. ; Kamenecka, Theodore M.

Chemistry – A European Journal, 05 July 2018, Vol.24(38), pp.9535-9541 [Peer Reviewed Journal]

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Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Solt, Laura A ; Wang, Yongjun ; Banerjee, Subhashis ; Hughes, Travis ; Kojetin, Douglas J ; Lundasen, Thomas ; Shin, Youseung ; Liu, Jin ; Cameron, Michael D ; Noel, Romain ; Yoo, Seung-Hee ; Takahashi, Joseph S ; Butler, Andrew A ; Kamenecka, Theodore M ; Burris, Thomas P

Nature, 29 March 2012, Vol.485(7396), pp.62-8 [Peer Reviewed Journal]

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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Solt, Laura A ; Kumar, Naresh ; Nuhant, Philippe ; Wang, Yongjun ; Lauer, Janelle L ; Liu, Jin ; Istrate, Monica A ; Kamenecka, Theodore M ; Roush, William R ; Vidović, Dušica ; Schürer, Stephan C ; Xu, Jihong ; Wagoner, Gail ; Drew, Paul D ; Griffin, Patrick R ; Burris, Thomas P

Nature, 28 April 2011, Vol.472(7344), pp.491-4 [Peer Reviewed Journal]

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Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation

Amador, Ariadna ; Huitron-Resendiz, Salvador ; Roberts, Amanda J ; Kamenecka, Theodore M ; Solt, Laura A ; Burris, Thomas P Cermakian, Nicolas (editor)

PLoS ONE, 2016, Vol.11(9) [Peer Reviewed Journal]

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9
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Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5

Choi, Jang Hyun ; Banks, Alexander S ; Estall, Jennifer L ; Kajimura, Shingo ; Boström, Pontus ; Laznik, Dina ; Ruas, Jorge L ; Chalmers, Michael J ; Kamenecka, Theodore M ; Blüher, Matthias ; Griffin, Patrick R ; Spiegelman, Bruce M

Nature, 22 July 2010, Vol.466(7305), pp.451-6 [Peer Reviewed Journal]

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Ablation of PM20D1 reveals -acyl amino acid control of metabolism and nociception

Long, Jonathan Z ; Roche, Alexander M ; Berdan, Charles A ; Louie, Sharon M ; Roberts, Amanda J ; Svensson, Katrin J ; Dou, Florence Y ; Bateman, Leslie A ; Mina, Amir I ; Deng, Zhaoming ; Jedrychowski, Mark P ; Lin, Hua ; Kamenecka, Theodore M ; Asara, John M ; Griffin, Patrick R ; Banks, Alexander S ; Nomura, Daniel K ; Spiegelman, Bruce M

Proceedings of the National Academy of Sciences of the United States of America, 17 July 2018, Vol.115(29), pp.E6937-E6945 [Peer Reviewed Journal]

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Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzodthiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy

Hughes, Travis S ; Shang, Jinsai ; Brust, Richard ; De Vera, Ian Mitchelle S ; Fuhrmann, Jakob ; Ruiz, Claudia ; Cameron, Michael D ; Kamenecka, Theodore M ; Kojetin, Douglas J

Journal of medicinal chemistry, 23 November 2016, Vol.59(22), pp.10335-10341 [Peer Reviewed Journal]

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12
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Structure–Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics

Frkic, Rebecca L ; He, Yuanjun ; Rodriguez, Beatriz B ; Chang, Mi Ra ; Kuruvilla, Dana ; Ciesla, Anthony ; Abell, Andrew D ; Kamenecka, Theodore M ; Griffin, Patrick R ; Bruning, John B Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Medicinal Chemistry, 09 May 2017, Vol.60(11) [Peer Reviewed Journal]

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GLP-1 acts on habenular avoidance circuits to control nicotine intake

Tuesta, Luis M ; Chen, Zuxin ; Duncan, Alexander ; Fowler, Christie D ; Ishikawa, Masago ; Lee, Brian R ; Liu, Xin-An ; Lu, Qun ; Cameron, Michael ; Hayes, Matthew R ; Kamenecka, Theodore M ; Pletcher, Matthew ; Kenny, Paul J

Nature neuroscience, May 2017, Vol.20(5), pp.708-716 [Peer Reviewed Journal]

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14
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Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration

Lin, Hua ; Long, Jonathan Z ; Roche, Alexander M ; Svensson, Katrin J ; Dou, Florence Y ; Chang, Mi Ra ; Strutzenberg, Timothy ; Ruiz, Claudia ; Cameron, Michael D ; Novick, Scott J ; Berdan, Charles A ; Louie, Sharon M ; Nomura, Daniel K ; Spiegelman, Bruce M ; Griffin, Patrick R ; Kamenecka, Theodore M

Journal of medicinal chemistry, 12 April 2018, Vol.61(7), pp.3224-3230 [Peer Reviewed Journal]

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15
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Discovery through Total Synthesis: A Retrospective on the Himastatin Problem

Kamenecka, TheodoreM. ; Danishefsky, Samuel J.

Chemistry – A European Journal, 05 January 2001, Vol.7(1), pp.41-63 [Peer Reviewed Journal]

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Kamenecka, Theodore M. ; Danishefsky, Samuel J.

Chemistry, 01/05/2001, Vol.7(1), pp.1-1 [Peer Reviewed Journal]

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17
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REV-ERBβ is required to maintain normal wakefulness and the wake-inducing effect of dual REV-ERB agonist SR9009

Amador, Ariadna ; Kamenecka, Theodore M ; Solt, Laura A ; Burris, Thomas P

Biochemical Pharmacology, April 2018, Vol.150, pp.1-8 [Peer Reviewed Journal]

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18
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Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REV-ERB

Kojetin, Douglas ; Wang, Yongjun ; Kamenecka, Theodore M ; Burris, Thomas P

ACS chemical biology, 18 February 2011, Vol.6(2), pp.131-4 [Peer Reviewed Journal]

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19
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Pharmacologic Repression of Retinoic Acid Receptor–Related Orphan Nuclear Receptor γ Is Therapeutic in the Collagen‐Induced Arthritis Experimental Model

Chang, Mi Ra ; Lyda, Brent ; Kamenecka, Theodore M. ; Griffin, Patrick R.

Arthritis & Rheumatology, March 2014, Vol.66(3), pp.579-588 [Peer Reviewed Journal]

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20
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Suppression of atherosclerosis by synthetic REV-ERB agonist

Sitaula, Sadichha ; Billon, Cyrielle ; Kamenecka, Theodore M ; Solt, Laura A ; Burris, Thomas P

Biochemical and Biophysical Research Communications, 08 May 2015, Vol.460(3), pp.566-571 [Peer Reviewed Journal]

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21
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Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors

Jain, Akansha ; Kuryatov, Alexander ; Wang, Jingyi ; Kamenecka, Theodore M ; Lindstrom, Jon

The Journal of biological chemistry, 04 November 2016, Vol.291(45), pp.23452-23463 [Peer Reviewed Journal]

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22
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Construction of substituted cyclohexanones by reductive cyclization of 7-oxo-2,8-alkadienyl esters

Kamenecka, Theodore M ; Overman, Larry E ; Ly Sakata, Sylvie K

Organic letters, 10 January 2002, Vol.4(1), pp.79-82 [Peer Reviewed Journal]

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23
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Synthesis and SAR of 2-Phenoxypyridines as novel c-Jun N-terminal kinase inhibitors

Song, Xinyi ; Chen, Weimin ; Lin, Li ; Ruiz, Claudia H ; Cameron, Michael D ; Duckett, Derek R ; Kamenecka, Theodore M

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(23), pp.7072-7075 [Peer Reviewed Journal]

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24
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A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit

Wang, Jingyi ; Kuryatov, Alexander ; Jin, Zhuang ; Norleans, Jack ; Kamenecka, Theodore M ; Kenny, Paul J ; Lindstrom, Jon

The Journal of biological chemistry, 27 November 2015, Vol.290(48), pp.28834-46 [Peer Reviewed Journal]

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25
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An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors

Wang, Jingyi ; Kuryatov, Alexander ; Sriram, Aarati ; Jin, Zhuang ; Kamenecka, Theodore M ; Kenny, Paul J ; Lindstrom, Jon

The Journal of biological chemistry, 29 May 2015, Vol.290(22), pp.13907-18 [Peer Reviewed Journal]

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26
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Identification of a selective RORγ ligand that suppresses T(H)17 cells and stimulates T regulatory cells

Solt, Laura A ; Kumar, Naresh ; He, Yuanjun ; Kamenecka, Theodore M ; Griffin, Patrick R ; Burris, Thomas P

ACS chemical biology, 21 September 2012, Vol.7(9), pp.1515-9 [Peer Reviewed Journal]

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27
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Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor

Brust, Richard ; Lin, Hua ; Fuhrmann, Jakob ; Asteian, Alice ; Kamenecka, Theodore M ; Kojetin, Douglas J

ACS chemical biology, 21 April 2017, Vol.12(4), pp.969-978 [Peer Reviewed Journal]

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28
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The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1)

Di Fruscia, Paolo ; He, Yuanjun ; Koenig, Marcel ; Tabrizifard, Sahba ; Nieto, Ainhoa ; Mcdonald, Patricia H ; Kamenecka, Theodore M

Bioorganic & Medicinal Chemistry Letters, 15 August 2014, Vol.24(16), pp.3974-3978 [Peer Reviewed Journal]

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29
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Imidazopyridines as selective CYP3A4 inhibitors

Song, Xinyi ; Li, Xiaohai ; Ruiz, Claudia H ; Yin, Yan ; Feng, Yangbo ; Kamenecka, Theodore M ; Cameron, Michael D

Bioorganic & Medicinal Chemistry Letters, 15 February 2012, Vol.22(4), pp.1611-1614 [Peer Reviewed Journal]

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30
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Enantioselective approach to 3-substituted prolines

Kamenecka, Theodore M ; Park, You-Jung ; Lin, Linus S ; Lanza, Thomas ; Hagmann, William K

Tetrahedron Letters, 2001, Vol.42(49), pp.8571-8573 [Peer Reviewed Journal]

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31
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Enantioselective synthesis of protected forms of (3 R,5 R)-5-hydroxypiperazic acid useful for synthesis

Depew, Kristopher M ; Kamenecka, Theodore M ; Danishefsky, Samuel J

Tetrahedron Letters, 2000, Vol.41(3), pp.289-292 [Peer Reviewed Journal]

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32
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Efficient methodology for the synthesis of 3-amino-1,2,4-triazoles

Noël, Romain ; Song, Xinyi ; Jiang, Rong ; Chalmers, Michael J ; Griffin, Patrick R ; Kamenecka, Theodore M

The Journal of organic chemistry, 02 October 2009, Vol.74(19), pp.7595-7 [Peer Reviewed Journal]

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33
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Studies in the Total Synthesis of Himastatin: A Revision of the Stereochemical Assignment

Kamenecka, Theodore M. ; Danishefsky, Samuel J.

Angewandte Chemie International Edition, 16 November 1998, Vol.37(21), pp.2993-2995 [Peer Reviewed Journal]

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34
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Total Synthesis of Himastatin: Confirmation of the Revised Stereostructure

Kamenecka, Theodore M. ; Danishefsky, Samuel J.

Angewandte Chemie International Edition, 16 November 1998, Vol.37(21), pp.2995-2998 [Peer Reviewed Journal]

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35
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Synthetic RORγt Agonists Enhance Protective Immunity

Chang, Mi Ra ; Dharmarajan, Venkatasubramanian ; Doebelin, Christelle ; Garcia-Ordonez, Ruben D ; Novick, Scott J ; Kuruvilla, Dana S ; Kamenecka, Theodore M ; Griffin, Patrick R

ACS chemical biology, 15 April 2016, Vol.11(4), pp.1012-8 [Peer Reviewed Journal]

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36
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Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists

Noel, Romain ; Song, Xinyi ; Shin, Youseung ; Banerjee, Subhashis ; Kojetin, Douglas ; Lin, Li ; Ruiz, Claudia H ; Cameron, Michael D ; Burris, Thomas P ; Kamenecka, Theodore M

Bioorganic & Medicinal Chemistry Letters, 01 June 2012, Vol.22(11), pp.3739-3742 [Peer Reviewed Journal]

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37
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Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors

Jin, Zhuang ; Khan, Pasha ; Shin, Youseung ; Wang, Jingyi ; Lin, Li ; Cameron, Michael D ; Lindstrom, Jon M ; Kenny, Paul J ; Kamenecka, Theodore M

Bioorganic & Medicinal Chemistry Letters, 15 January 2014, Vol.24(2), pp.674-678 [Peer Reviewed Journal]

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