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1
Microwave Digestion--Vacuum Filtration-Automated Scanning Electron Microscopy as a sensitive method for forensic diatom test
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Microwave Digestion--Vacuum Filtration-Automated Scanning Electron Microscopy as a sensitive method for forensic diatom test

Jian Zhao ; Chao Liu ; Sunlin Hu ; Shuwen He ; Siya Lu

International journal of legal medicine, 2013-03-01, Vol.127 (2), p.459 [Peer Reviewed Journal]

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2
Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model
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Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

Gao, Rui ; Liu, Yanxia ; Gjesing, Anette Prior ; Hollensted, Mette ; Wan, Xianzi ; He, Shuwen ; Pedersen, Oluf ; Yi, Xin ; Wang, Jun ; Hansen, Torben

BMC genetics, 2014-01-29, Vol.15 (1), p.13-13 [Peer Reviewed Journal]

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3
Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors
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Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors

Muise, Eric S ; Zhu, Yonghua ; Verras, Andreas ; Karanam, Bindhu V ; Gorski, Judith ; Weingarth, Drew ; Lin, Hua V ; Hwa, Joyce ; Thompson, John R ; Hu, Guanghui ; Liu, Jian ; He, Shuwen ; DeVita, Robert J ; Shen, Dong-Ming ; Pinto, Shirly Slominski, Andrzej T

PloS one, 2014, Vol.9 (2), p.e88908 [Peer Reviewed Journal]

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4
Robust Visual Correlation Tracking
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Robust Visual Correlation Tracking

Zhang, Lei ; Wang, Yanjie ; Sun, Honghai ; Yao, Zhijun ; He, Shuwen Gaeta, Matteo

Mathematical problems in engineering, 2015-09-30, Vol.2015, p.1-13 [Peer Reviewed Journal]

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5
Polyproline II structure is critical for the enzyme protective function of soybean Em (LEA1) conserved domains
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Polyproline II structure is critical for the enzyme protective function of soybean Em (LEA1) conserved domains

Yongdong Zou ; Ruisha Hong ; Shuwen He ; Guobao Liu ; Zebo Huang ; Yizhi Zheng

Biotechnology letters, 2011-08-01, Vol.33 (8), p.1667 [Peer Reviewed Journal]

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6
Potential mechanism of enhanced postprandial glucagon-like peptide-1 release following treatment with a diacylglycerol acyltransferase 1 inhibitor
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Potential mechanism of enhanced postprandial glucagon-like peptide-1 release following treatment with a diacylglycerol acyltransferase 1 inhibitor

Liu, Jinqi ; McLaren, David G ; Chen, Dunlu ; Kan, Yanqing ; Stout, Steven J ; Shen, Xiaolan ; Murphy, Beth Ann ; Forrest, Gail ; Karanam, Bindhu ; Sonatore, Lisa ; He, Shuwen ; Roddy, Thomas P ; Pinto, Shirly

Pharmacology research & perspectives, 2015, Vol.3 (6), p.e00193-n/a [Peer Reviewed Journal]

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7
Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety
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Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Yang, David X ; Ting, Pauline C ; Kuethe, Jeffrey T ; Cernak, Timothy A ; Dykstra, Kevin D ; Sperbeck, Donald M ; Wu, Zhicai ; Yu, Yang ; Yang, Ginger X ; Jian, Tianying ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Sonatore, Lisa M ; Wiltsie, Judyann ; Liu, Jinqi ; Gorski, Judith N ; Chung, Christine C ; Gibson, Jack T ; Lisnock, JeanMarie ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; DeVita, Robert J

ACS medicinal chemistry letters, 2014-10-09, Vol.5 (10), p.1082-1087 [Peer Reviewed Journal]

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8
Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes
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Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Shah, Shrenik K ; He, Shuwen ; Guo, Liangqin ; Truong, Quang ; Qi, Hongbo ; Du, Wu ; Lai, Zhong ; Liu, Jian ; Jian, Tianying ; Hong, Qingmei ; Dobbelaar, Peter ; Ye, Zhixiong ; Sherer, Edward ; Feng, Zhe ; Yu, Yang ; Wong, Frederick ; Samuel, Koppara ; Madiera, Maria ; Karanam, Bindhu V ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Feng, Yue ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Eiermann, George J ; Li, Cai ; Pachanski, Michele ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Morissette, Pierre ; Volksdorf, Sylvia ; Kerr, Janet ; Zhang, Bei B ; Howard, Andrew D ; Zhou, Yun-Ping ; Pasternak, Alexander ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 2015-05-14, Vol.6 (5), p.513-517 [Peer Reviewed Journal]

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9
Novel sRNA and regulatory genes repressing the adhesion of Salmonella enteritidis exposed to meat-related environment
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Novel sRNA and regulatory genes repressing the adhesion of Salmonella enteritidis exposed to meat-related environment

Hu, Haijing ; Jia, Kun ; Wang, Huhu ; Xu, Xinglian ; Zhou, Guanghong ; He, Shuwen

Food control, 2020-04, Vol.110, p.107030 [Peer Reviewed Journal]

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10
Multi-step parallel synthesis enabled optimization of benzofuran derivatives as pan-genotypic non-nucleoside inhibitors of HCV NS5B
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Multi-step parallel synthesis enabled optimization of benzofuran derivatives as pan-genotypic non-nucleoside inhibitors of HCV NS5B

Xiao, Dong ; Dai, Xing ; Liu, Hong ; He, Shuwen ; Shi, Zhi-Cai ; Ludmerer, Steven W ; Li, Fangbiao ; Nargund, Ravi ; Palani, Anandan

Bioorganic & medicinal chemistry letters, 2020-04-01, Vol.30 (7), p.127004 [Peer Reviewed Journal]

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11
Two novel calreticulin-related molecules with microbial binding and phagocytosis enhancing capacity in the half-smooth tongue sole, Cynoglossus semilaevis
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Two novel calreticulin-related molecules with microbial binding and phagocytosis enhancing capacity in the half-smooth tongue sole, Cynoglossus semilaevis

Wang, Guanghua ; Jiang, Zengjie ; He, Shuwen ; Zhang, Min

Fish & shellfish immunology, 2018-01, Vol.72, p.174-180 [Peer Reviewed Journal]

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12
Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase
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Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase

Liu, Hong ; Dai, Xing ; He, Shuwen ; Brockunier, Linda ; Marcantonio, Karen ; Ludmerer, Steven W ; Li, Fangbiao ; Feng, Kung-I ; Nargund, Ravi P ; Palani, Anandan

Bioorganic & medicinal chemistry letters, 2019-12-15, Vol.29 (24), p.126104 [Peer Reviewed Journal]

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13
Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl‑1H‑benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors
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Article
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Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl‑1H‑benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors

Cernak, Tim ; Gesmundo, Nathan J ; Dykstra, Kevin ; Yu, Yang ; Wu, Zhicai ; Shi, Zhi-Cai ; Vachal, Petr ; Sperbeck, Donald ; He, Shuwen ; Murphy, Beth Ann ; Sonatore, Lisa ; Williams, Steven ; Madeira, Maria ; Verras, Andreas ; Reiter, Maud ; Lee, Claire Heechoon ; Cuff, James ; Sherer, Edward C ; Kuethe, Jeffrey ; Goble, Stephen ; Perrotto, Nicholas ; Pinto, Shirly ; Shen, Dong-Ming ; Nargund, Ravi ; Balkovec, James ; DeVita, Robert J ; Dreher, Spencer D

Journal of medicinal chemistry, 2017-05-11, Vol.60 (9), p.3594-3605 [Peer Reviewed Journal]

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14
Community structure of Rotifera and eutrophication evaluation of Nansha Mangal-Wetland Park in Guangzhou City
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Conference Proceeding
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Community structure of Rotifera and eutrophication evaluation of Nansha Mangal-Wetland Park in Guangzhou City

Yu, Fei ; He, Shuwen ; Liu, Yu ; Yao, Xin ; Sun, Qinyu

IOP conference series. Earth and environmental science, 2019-09-05, Vol.310, p.52013 [Peer Reviewed Journal]

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15
Residual and migration characteristics of norfloxacin in two mangrove ecosystems
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Conference Proceeding
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Residual and migration characteristics of norfloxacin in two mangrove ecosystems

Li, Ling ; Liu, Yu ; Sun, Qinyu ; Yu, Fei ; He, Shuwen

IOP conference series. Earth and environmental science, 2019-09-05, Vol.310, p.52017 [Peer Reviewed Journal]

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16
Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC)
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Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC)

Yu, Yang ; Wu, Zhicai ; Shi, Zhi-Cai ; He, Shuwen ; Lai, Zhong ; Cernak, Timothy A ; Vachal, Petr ; Liu, Min ; Liu, Jian ; Hong, Qingmei ; Jian, Tianying ; Guiadeen, Deodial ; Krikorian, Arto ; Sperbeck, Donald M ; Verras, Andreas ; Sonatore, Lisa M ; Murphy, Beth A ; Wiltsie, Judyann ; Chung, Christine C ; Gorski, Judith N ; Liu, Jinqi ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; De Vita, Robert J ; Pinto, Shirly ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2019-06-01, Vol.29 (11), p.1380-1385 [Peer Reviewed Journal]

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17
Synthesis of novel 2-azabicyclo[3.1.1]heptane-5-carboxylic acid
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Synthesis of novel 2-azabicyclo[3.1.1]heptane-5-carboxylic acid

He, Shuwen ; Hao, Jinsong ; Ashley, Eric R ; Chobanian, Harry R ; Pio, Barbara ; Colletti, Steven L ; Miller, Michael

Tetrahedron letters, 2016-03-16, Vol.57 (11), p.1268-1269 [Peer Reviewed Journal]

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18
A general approach to access 5,6-dihydroindolo-naphthyridine ring system
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Article
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A general approach to access 5,6-dihydroindolo-naphthyridine ring system

He, Shuwen ; Li, Peng ; Dai, Xing ; Liu, Hong ; Lai, Zhong ; Xiao, Dong ; McComas, Casey C ; Du, Chunyan ; Liu, Yuehui ; Yin, Jingjun ; Dang, Qun ; Zorn, Nicolas ; Peng, Xuanjia ; Nargund, Ravi P ; Palani, Anandan

Tetrahedron letters, 2017-04-05, Vol.58 (14), p.1373-1375 [Peer Reviewed Journal]

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19
Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety
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Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety

He, Shuwen ; Lai, Zhong ; Hong, Qingmei ; Shang, Jackie ; Reibarkh, Mikhail ; Kuethe, Jeffrey T ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Cernak, Timothy A ; Dykstra, Kevin D ; Sperbeck, Donald M ; Wu, Zhicai ; Yu, Yang ; Yang, Ginger X ; Jian, Tianying ; Verras, Andreas ; Sonatore, Lisa M ; Wiltsie, Judyann ; Chung, Christine C ; Murphy, Beth A ; Gorski, Judith N ; Liu, Jinqi ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; DeVita, Robert J

Bioorganic & medicinal chemistry letters, 2019-05-15, Vol.29 (10), p.1182-1186 [Peer Reviewed Journal]

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20
A biocatalytic/reductive etherification approach to substituted piperidinyl ethers
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A biocatalytic/reductive etherification approach to substituted piperidinyl ethers

Kuethe, Jeffrey T ; Janey, Jacob M ; Truppo, Matthew ; Arredondo, Juan ; Li, Tao ; Yong, Kelvin ; He, Shuwen

Tetrahedron, 2014-07-29, Vol.70 (30), p.4563-4570 [Peer Reviewed Journal]

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21
SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists
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SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Dobbelaar, Peter H ; Guo, Liangqin ; Ye, Zhixiong ; Liu, Jian ; Jian, Tianying ; Truong, Quang ; Shah, Shrenik K ; Du, Wu ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James D ; Sherer, Edward ; Pasternak, Alexander ; Feng, Zhe ; Reibarkh, Mikhail ; Lin, Melissa ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei B ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & medicinal chemistry letters, 2016, Vol.26 (6), p.1529-1535 [Peer Reviewed Journal]

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22
Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists
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Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists

Lai, Zhong ; He, Shuwen ; Sherer, Edward C ; Wu, Zhicai ; Yu, Yang ; Ball, Richard ; Hong, Qingmei ; Yang, David X ; Guo, Liangqing ; Li, Derun ; Tuang, Quang ; Chicchi, Gary G ; Trusca, Dorina ; Tsao, Kwei-Lan ; Zhou, Yun-Ping ; Howard, Andrew D ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & medicinal chemistry letters, 2015, Vol.25 (17), p.3520-3525 [Peer Reviewed Journal]

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23
Facile functionalization at the C2 position of a highly substituted benzofuran
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Facile functionalization at the C2 position of a highly substituted benzofuran

He, Shuwen ; Li, Peng ; Dai, Xing ; McComas, Casey C ; Du, Chunyan ; Wang, Ping ; Lai, Zhong ; Liu, Hong ; Yin, Jingjun ; Bulger, Paul G ; Dang, Qun ; Xiao, Dong ; Zorn, Nicolas ; Peng, Xuanjia ; Nargund, Ravi P ; Palani, Anandan

Tetrahedron letters, 2014-04-02, Vol.55 (14), p.2212-2216 [Peer Reviewed Journal]

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24
A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization
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A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization

He, Shuwen ; Li, Peng ; Dai, Xing ; McComas, Casey C ; Huang, Hongling ; Zhan, Chaoliang ; Chang, Liang ; Liu, Yuehui ; Chen, Shaojun ; Lai, Zhong ; Liu, Hong ; Yin, Jingjun ; Dang, Qun ; Xiao, Dong ; Zorn, Nicolas ; Peng, Xuanjia ; Nargund, Ravi P ; Palani, Anandan

Tetrahedron letters, 2013-07-17, Vol.54 (29), p.3755-3758 [Peer Reviewed Journal]

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25
Synthesis of [beta]-carbolines from aldehydes and ketones via the [alpha]-siloxy [alpha],[beta]-unsaturated esters
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Synthesis of [beta]-carbolines from aldehydes and ketones via the [alpha]-siloxy [alpha],[beta]-unsaturated esters

He, Shuwen ; Lai, Zhong ; Yang, David X ; Hong, Qingmei ; Reibarkh, Mikhail ; Nargund, Ravi P ; Hagmann, William K

Tetrahedron letters, 2010-08-18, Vol.51 (33), p.4361 [Peer Reviewed Journal]

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26
Synthesis of β-carbolines from aldehydes and ketones via the α-siloxy α,β-unsaturated esters
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Synthesis of β-carbolines from aldehydes and ketones via the α-siloxy α,β-unsaturated esters

He, Shuwen ; Lai, Zhong ; Yang, David X ; Hong, Qingmei ; Reibarkh, Mikhail ; Nargund, Ravi P ; Hagmann, William K

Tetrahedron letters, 2010, Vol.51 (33), p.4361-4364 [Peer Reviewed Journal]

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27
Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity
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Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity

Liu, Jian ; He, Shuwen ; Jian, Tianying ; Dobbelaar, Peter H ; Sebhat, Iyassu K ; Lin, Linus S ; Goodman, Allan ; Guo, Cheng ; Guzzo, Peter R ; Hadden, Mark ; Henderson, Alan J ; Pattamana, Kevin ; Ruenz, Megan ; Sargent, Bruce J ; Swenson, Brian ; Yet, Larry ; Tamvakopoulos, Constantin ; Peng, Qianping ; Pan, Jie ; Kan, Yanqing ; Palyha, Oksana ; Kelly, Theresa M ; Guan, Xiao-Ming ; Howard, Andrew D ; Marsh, Donald J ; Metzger, Joseph M ; Reitman, Marc L ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (7), p.2074-2077 [Peer Reviewed Journal]

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28
Catalytic asymmetric hydrogenation to access spiroindane dimethyl acetic acid
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Catalytic asymmetric hydrogenation to access spiroindane dimethyl acetic acid

He, Shuwen ; Shultz, C. Scott ; Lai, Zhong ; Eid, Ronsar ; Dobbelaar, Peter H ; Ye, Zhixiong ; Nargund, Ravi P

Tetrahedron letters, 2011-07-13, Vol.52 (28), p.3621-3624 [Peer Reviewed Journal]

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29
Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity
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Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity

Hadden, Mark ; Goodman, Allan ; Guo, Cheng ; Guzzo, Peter R ; Henderson, Alan J ; Pattamana, Kevin ; Ruenz, Megan ; Sargent, Bruce J ; Swenson, Brian ; Yet, Larry ; Liu, Jian ; He, Shuwen ; Sebhat, Iyassu K ; Lin, Linus S ; Tamvakopoulos, Constantin ; Peng, Qianping ; Kan, Yanqing ; Palyha, Oksana ; Kelly, Theresa M ; Guan, Xiao-Ming ; Metzger, Joseph M ; Reitman, Marc L ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (9), p.2912-2915 [Peer Reviewed Journal]

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30
Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst 3 Antagonist
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Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst 3 Antagonist

Pasternak, Alexander ; Feng, Zhe ; de Jesus, Reynalda ; Ye, Zhixiong ; He, Shuwen ; Dobbelaar, Peter ; Bradley, Scott A ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Eiermann, George J ; Li, Cai ; Feng, Yue ; Wu, Margaret ; Shao, Qing ; Zhang, Bei B ; Nargund, Ravi ; Mills, Sander G ; Howard, Andrew D ; Yang, Lihu ; Zhou, Yun-Ping

ACS medicinal chemistry letters, 2012, Vol.3 (4), p.289-293 [Peer Reviewed Journal]

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31
Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity
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Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity

He, Shuwen ; Ye, Zhixiong ; Dobbelaar, Peter H ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James P ; Sebhat, Iyassu K ; Guo, Liangqin ; Liu, Jian ; Jian, Tianying ; Lai, Yingjie ; Franklin, Christopher L ; Reibarkh, Mikhail ; Holmes, Mark A ; Weinberg, David H ; MacNeil, Tanya ; Tang, Rui ; Tamvakopoulos, Constantin ; Peng, Qianping ; Miller, Randy R ; Stearns, Ralph A ; Chen, Howard Y ; Chen, Airu S ; Strack, Alison M ; Fong, Tung M ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (22), p.6524-6532 [Peer Reviewed Journal]

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Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists
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Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists

He, Shuwen ; Dobbelaar, Peter H ; Liu, Jian ; Jian, Tianying ; Sebhat, Iyassu K ; Lin, Linus S ; Goodman, Allan ; Guo, Cheng ; Guzzo, Peter R ; Hadden, Mark ; Henderson, Alan J ; Ruenz, Megan ; Sargent, Bruce J ; Yet, Larry ; Kelly, Theresa M ; Palyha, Oksana ; Kan, Yanqing ; Pan, Jie ; Chen, Howard ; Marsh, Donald J ; Shearman, Lauren P ; Strack, Alison M ; Metzger, Joseph M ; Feighner, Scott D ; Tan, Carina ; Howard, Andrew D ; Tamvakopoulos, Constantin ; Peng, Qianping ; Guan, Xiao-Ming ; Reitman, Marc L ; Patchett, Arthur A ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (6), p.1913-1917 [Peer Reviewed Journal]

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33
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist
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Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

Hong, Qingmei ; Bakshi, Raman K ; Palucki, Brenda L ; Park, Min K ; Ye, Zhixiong ; He, Shuwen ; Pollard, Patrick G ; Sebhat, Iyassu K ; Liu, Jian ; Guo, Liangqin ; Cashen, Doreen E ; Martin, William J ; Weinberg, David H ; MacNeil, Tanya ; Tang, Rui ; Tamvakopoulos, Constantin ; Peng, Qianping ; Miller, Randy R ; Stearns, Ralph A ; Chen, Howard Y ; Chen, Airu S ; Strack, Alison M ; Fong, Tung M ; MacIntyre, D. Euan ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (8), p.2330-2334 [Peer Reviewed Journal]

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Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity
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Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity

He, Shuwen ; Ye, Zhixiong ; Dobbelaar, Peter H ; Sebhat, Iyassu K ; Guo, Liangqin ; Liu, Jian ; Jian, Tianying ; Lai, Yingjie ; Franklin, Christopher L ; Bakshi, Raman K ; Dellureficio, James P ; Hong, Qingmei ; Weinberg, David H ; MacNeil, Tanya ; Tang, Rui ; Strack, Alison M ; Tamvakopoulos, Constantin ; Peng, Qianping ; Miller, Randy R ; Stearns, Ralph A ; Chen, Howard Y ; Chen, Airu S ; Fong, Tung M ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (15), p.4399-4405 [Peer Reviewed Journal]

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35
Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists
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Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Lai, Zhong ; Ye, Zhixiong ; Dobbelaar, Peter H ; Shah, Shrenik K ; Truong, Quang ; Du, Wu ; Guo, Liangqin ; Liu, Jian ; Jian, Tianying ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James ; Reibarkh, Mikhail ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 2014-07-10, Vol.5 (7), p.748-753 [Peer Reviewed Journal]

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