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Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic pain

Smith, Terika ; Haymond, Tami ; Smith, Sherika ; Sweitzer, Sarah

Journal of Pain Research, pp.531-545 [Peer Reviewed Journal]

2014

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Immunotherapy and endothelin receptor antagonists for treatment of castration‐resistant prostate cancer

Shao, Ning ; Wang, Yang ; Jiang, Wen Yu ; Qiao, Di ; Zhang, Shi Ge ; Wu, Ye ; Zhang, Xiang Xiang ; Wang, Jiu Ling ; Ding, Yi ; Feng, Ning Han

International Journal of Cancer, 01 October 2013, Vol.133(7), pp.1743-1750 [Peer Reviewed Journal]

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Management of Pulmonary Arterial Hypertension

Mclaughlin, Vallerie V ; Shah, Sanjiv J ; Souza, Rogerio ; Humbert, Marc

Journal of the American College of Cardiology, 12 May 2015, Vol.65(18), pp.1976-1997 [Peer Reviewed Journal]

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Endothelin receptor-antagonists suppress lipopolysaccharide-induced cytokine release from alveolar macrophages of non-smokers, smokers and COPD subjects

Gerlach, Kathrin ; Köhler-Bachmann, Stefanie ; Jungck, David ; Körber, Sandra ; Yanik, Sarah ; Knoop, Heiko ; Wehde, Deborah ; Rheinländer, Sonja ; Walther, Jörg W ; Kronsbein, Juliane ; Knobloch, Jürgen ; Koch, Andrea

European Journal of Pharmacology, 05 December 2015, Vol.768, pp.123-130 [Peer Reviewed Journal]

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Distinct ETA receptor binding mode of macitentan as determined by site directed mutagenesis

Gatfield, John ; Mueller Grandjean, Celia ; Bur, Daniel ; Bolli, Martin H ; Nayler, Oliver

PloS one, 2014, Vol.9(9), pp.e107809 [Peer Reviewed Journal]

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The Role of Endothelin System in Renal Structure and Function during the Postnatal Development of the Rat Kidney

Albertoni Borghese, María F ; Ortiz, María C ; Balonga, Sabrina ; Moreira Szokalo, Rocío ; Majowicz, Mónica P

PloS one, 2016, Vol.11(2), pp.e0148866 [Peer Reviewed Journal]

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Iontophoresis of endothelin receptor antagonists in rats and men

Roustit, Matthieu ; Blaise, Sophie ; Arnaud, Claire ; Hellmann, Marcin ; Millet, Claire ; Godin-Ribuot, Diane ; Dufournet, Boris ; Boutonnat, Jean ; Ribuot, Christophe ; Cracowski, Jean-Luc

PloS one, 2012, Vol.7(7), pp.e40792 [Peer Reviewed Journal]

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Comparative efficacy and acceptability of endothelin receptor antagonists for pulmonary arterial hypertension: A network meta-analysis

Duo-Ji, Mi-Ma ; Long, Zi-Wen

International Journal of Cardiology, 01 May 2017, Vol.234, pp.90-98 [Peer Reviewed Journal]

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Endothelin receptor antagonists for the treatment of pulmonary artery hypertension

Rubin, Lewis J

Life Sciences, 15 October 2012, Vol.91(13-14), pp.517-521 [Peer Reviewed Journal]

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The profibrotic role of endothelin-1: Is the door still open for the treatment of fibrotic diseases?

Rodríguez-Pascual, Fernando ; Busnadiego, Oscar ; González-Santamaría, José

Life Sciences, 24 November 2014, Vol.118(2), pp.156-164 [Peer Reviewed Journal]

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Updated Treatment Algorithm of Pulmonary Arterial Hypertension

Galiè, Nazzareno ; Corris, Paul A ; Frost, Adaani ; Girgis, Reda E ; Granton, John ; Jing, Zhi Cheng ; Klepetko, Walter ; Mcgoon, Michael D ; Mclaughlin, Vallerie V ; Preston, Ioana R ; Rubin, Lewis J ; Sandoval, Julio ; Seeger, Werner ; Keogh, Anne

Journal of the American College of Cardiology, 24 December 2013, Vol.62(25), pp.D60-D72 [Peer Reviewed Journal]

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Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice

Kim, Sun-Jin ; Lee, Ho Jeong ; Kim, Mark Seungwook ; Choi, Hyun Jin ; He, Junqin ; Wu, Qiuyu ; Aldape, Kenneth ; Weinberg, Jeffrey S ; Yung, W K Alfred ; Conrad, Charles A ; Langley, Robert R ; Lehembre, François ; Regenass, Urs ; Fidler, Isaiah J

Clinical cancer research : an official journal of the American Association for Cancer Research, 15 October 2015, Vol.21(20), pp.4630-41 [Peer Reviewed Journal]

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Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung disease

Romaniello, Antonella ; Gigante, Antonietta ; Di Paolo, Marcello ; Tallerini, Gaia ; Barbano, Biagio ; Amoroso, Daria ; Palange, Paolo ; Rosato, Edoardo

International Journal of Cardiology, 15 November 2016, Vol.223, pp.113-115 [Peer Reviewed Journal]

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The Twelfth International Conference on Endothelin (ET-12), Cambridge 2011

Barton, Matthias ; Davenport, Anthony P

Life Sciences, 15 October 2012, Vol.91(13-14), pp.462-465 [Peer Reviewed Journal]

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Endothelin receptor antagonists in clinical research — Lessons learned from preclinical and clinical kidney studies

Reichetzeder, Christoph ; Tsuprykov, Oleg ; Hocher, Berthold

Life Sciences, 24 November 2014, Vol.118(2), pp.141-148 [Peer Reviewed Journal]

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Combination of sitaxentan and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan

Faruqi, S ; Fathi, H ; Morice, A.H

International Journal of Cardiology, 2010, Vol.144(3), pp.e43-e45 [Peer Reviewed Journal]

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18
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Untangling the Knot in Diabetic Nephropathy: The Unanticipated Role of Glycocalyx in the Antiproteinuric Effect of Endothelin Receptor Antagonists

Buelli, Simona ; Perico, Luca ; Benigni, Ariela

Diabetes, August 2016, Vol.65(8), pp.2115-7 [Peer Reviewed Journal]

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19
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L'endothéline : de la découverte aux avancées pharmacothérapeutiques.
Endothelin: From discovery to pharmacotherapeutic innovations

Richard, Vincent

Presse medicale (Paris, France : 1983), 2014, Vol.43(7-8), pp.742-55 [Peer Reviewed Journal]

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20
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Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice

Michinaga, Shotaro ; Nagase, Marina ; Matsuyama, Emi ; Yamanaka, Daisuke ; Seno, Naoki ; Fuka, Mayu ; Yamamoto, Yui ; Koyama, Yutaka

PloS one, 2014, Vol.9(7), pp.e102009 [Peer Reviewed Journal]

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21
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Evaluation of the endothelin receptor antagonists ambrisentan, bosentan, macitentan, and sitaxsentan as hepatobiliary transporter inhibitors and substrates in sandwich-cultured human hepatocytes

Lepist, Eve-Irene ; Gillies, Hunter ; Smith, William ; Hao, Jia ; Hubert, Cassandra ; St Claire, Robert L ; Brouwer, Kenneth R ; Ray, Adrian S

PloS one, 2014, Vol.9(1), pp.e87548 [Peer Reviewed Journal]

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22
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Targeted therapy of pulmonary arterial hypertension: Updated recommendations from the Cologne Consensus Conference 2018

Hoeper, Marius M ; Apitz, Christian ; Grünig, Ekkehard ; Halank, Michael ; Ewert, Ralf ; Kaemmerer, Harald ; Kabitz, Hans-Joachim ; Kähler, Christian ; Klose, Hans ; Leuchte, Hanno ; Ulrich, Silvia ; Olsson, Karen M ; Distler, Oliver ; Rosenkranz, Stephan ; Ghofrani, H. Ardeschir

International Journal of Cardiology, 01 December 2018, Vol.272, pp.37-45 [Peer Reviewed Journal]

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23
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What is the best method of proteinuria measurement in clinical trials of endothelin receptor antagonists?

Towler, Jonathan D ; Dhaun, Neeraj ; Macdougall, Margaret ; Melville, Vanessa ; Goddard, Jane ; Webb, David J

Life Sciences, 15 October 2012, Vol.91(13-14), pp.733-738 [Peer Reviewed Journal]

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24
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Endothelin‐receptor antagonists for diabetic nephropathy: A meta‐analysis

Yuan, Wenming ; Li, Yi ; Wang, Ji ; Li, Jing ; Gou, Shenju ; Fu, Ping

Nephrology, July 2015, Vol.20(7), pp.459-466 [Peer Reviewed Journal]

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25
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Clinical Adverse Effects of Endothelin Receptor Antagonists: Insights From the Meta‐Analysis of 4894 Patients From 24 Randomized Double‐Blind Placebo‐Controlled Clinical Trials

Wei, Anhua ; Gu, Zhichun ; Li, Juan ; Liu, Xiaoyan ; Wu, Xiaofan ; Han, Yi ; Pu, Jun

Journal of the American Heart Association, November 2016, Vol.5(11), pp.n/a-n/a [Peer Reviewed Journal]

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26
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Endothelin Receptor Antagonists are an Effective Long Term Treatment Option in Pulmonary Arterial Hypertension Associated with Congenital Heart Disease With or Without Trisomy 21

Kermeen, F.D ; Franks, C ; O’brien, K ; Seale, H ; Hall, K ; Mcneil, K ; Radford, D

Heart, Lung and Circulation, 2010, Vol.19(10), pp.595-600 [Peer Reviewed Journal]

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27
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Hypertension: Endothelin-receptor antagonists for treating hypertension

Weir, Matthew R

Nature reviews. Nephrology, April 2010, Vol.6(4), pp.192-4 [Peer Reviewed Journal]

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28
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Interaction profile of macitentan, a new non-selective endothelin-1 receptor antagonist, in vitro

Weiss, Johanna ; Theile, Dirk ; Rüppell, Maximilian Alexander ; Speck, Tobias ; Spalwisz, Adriana ; Haefeli, Walter Emil

European journal of pharmacology, 15 February 2013, Vol.701(1-3), pp.168-75 [Peer Reviewed Journal]

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29
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Endothelin receptor antagonist attenuates oxidative stress in a neonatal sepsis piglet model

Goto, Tatenobu ; Hussein, Mohamed Hamed ; Kato, Shin ; Daoud, Ghada Abdel-Hamid ; Kato, Takenori ; Sugiura, Takahiro ; Kakita, Hiroki ; Nobata, Masanori ; Kamei, Michi ; Mizuno, Haruo ; Imai, Masaki ; Ito, Tetsuya ; Kato, Ineko ; Suzuki, Satoshi ; Okada, Noriko ; Togari, Hajime ; Okada, Hidechika

Pediatric research, December 2012, Vol.72(6), pp.600-5 [Peer Reviewed Journal]

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30
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Endothelin receptor antagonists – a brief description of the new class of drugs

Agata Kowalczyk ; Michał Kołodziejczyk ; Anna Gorąca

Postępy Higieny i Medycyny Doświadczalnej, 01 January 2014, Vol.68, pp.1076-1080 [Peer Reviewed Journal]

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31
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EXPERIENCE OF USING THE NON­SELECTIVE ENDOTHELIN RECEPTOR ANTAGONIST MACITENTAN IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION

M. A. Simakova ; N. S. Goncharova ; E. V. Karelkina ; O. M. Moiseeva

Кардиоваскулярная терапия и профилактика [Peer Reviewed Journal]

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32
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The rise and fall of endothelin receptor antagonists in congestive heart failure

Handoko, M L ; De Man, F S ; Vonk-Noordegraaf, A

The European respiratory journal, March 2011, Vol.37(3), pp.484-5 [Peer Reviewed Journal]

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33
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Bosentan ameliorates the expression of fibrotic related growth factors and collagen-1 in diabetic mice

Yang, Bo ; Li, Min ; Shi, Zhen-Guo ; Feng, Quan-Zhou

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, December 2012, Vol.12(8), pp.621-7 [Peer Reviewed Journal]

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34
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Inflammatory responses of airway smooth muscle cells and effects of endothelin receptor antagonism

Knobloch, Jürgen ; Lin, Yingfeng ; Konradi, Jürgen ; Jungck, David ; Behr, Juergen ; Strauch, Justus ; Stoelben, Erich ; Koch, Andrea

American journal of respiratory cell and molecular biology, July 2013, Vol.49(1), pp.114-27 [Peer Reviewed Journal]

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35
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Pulmonary hypertension: reasonable selection of specific therapy

Karoli N.A ; Sazhnova S.I ; Rebrov A.P

Системные гипертензии [Peer Reviewed Journal]

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36
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New perspectives on the endothelin axis in pain

Barr, Travis P ; Kam, Sarah ; Khodorova, Alla ; Montmayeur, Jean-Pierre ; Strichartz, Gary R

Pharmacological research, June 2011, Vol.63(6), pp.532-40 [Peer Reviewed Journal]

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Endothelin: from bench to bedside and back

Dashwood, Michael R ; Abraham, David

Pharmacological research, June 2011, Vol.63(6), pp.445-7 [Peer Reviewed Journal]

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