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1
The synthesis and use of [14C]carbon monoxide in Pd-catalyzed carbonylation reactions
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The synthesis and use of [14C]carbon monoxide in Pd-catalyzed carbonylation reactions

Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, 2010, pp.n/a-n/a [Peer Reviewed Journal]

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2
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An integrated strategy for in vivo metabolite profiling using high-resolution mass spectrometry based data processing techniques

Guo, Jian ; Zhang, Minli ; Elmore, Charles S ; Vishwanathan, Karthick

Analytica Chimica Acta, 30 May 2013, Vol.780, pp.55-64 [Peer Reviewed Journal]

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3
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Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters

Testa, Andrea ; Dall’angelo, Sergio ; Mingarelli, Marco ; Augello, Andrea ; Schweiger, Lutz ; Welch, Andy ; Elmore, Charles S ; Sharma, Pradeep ; Zanda, Matteo

Bioorganic & Medicinal Chemistry, 01 February 2017, Vol.25(3), pp.963-976 [Peer Reviewed Journal]

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4
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Isotope chemistry; a useful tool in the drug discovery arsenal

Elmore, Charles S ; Bragg, Ryan A

Bioorganic & Medicinal Chemistry Letters, 15 January 2015, Vol.25(2), pp.167-171 [Peer Reviewed Journal]

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5
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Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors

Moran, Matthew D ; Wilson, Alan A ; Elmore, Charles S ; Parkes, Jun ; Ng, Alvina ; Sadovski, Oleg ; Graff, Ariel ; Daskalakis, Zafiris J ; Houle, Sylvain ; Chapdelaine, Marc J ; Vasdev, Neil

Bioorganic & Medicinal Chemistry, 15 July 2012, Vol.20(14), pp.4482-4488 [Peer Reviewed Journal]

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6
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[ 125I]YP20: A novel radioligand specific for the extracellular domain of the CRF 1 receptor

Gordon, John C ; Edwards, Phil ; Elmore, Charles S ; Lazor, Lois Ann ; Paschetto, Kathy ; Bostwick, Robert ; Sylvester, Mark ; Mauger, Russ ; Scott, Clay ; Aharony, David

European Journal of Pharmacology, 2010, Vol.649(1), pp.59-63 [Peer Reviewed Journal]

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7
Synthesis of triphenylsilyl[14C2]acetylene for use in a Sonogashira reaction
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Synthesis of triphenylsilyl[14C2]acetylene for use in a Sonogashira reaction

Elmore, Charles S. ; Dorff, Peter N.

Journal of Labelled Compounds and Radiopharmaceuticals, 01/2011, Vol.54(1), pp.51-53 [Peer Reviewed Journal]

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8
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Synthesis of ximelagatran, melagatran, hydroxymelagatran, and ethylmelagatran in H‐3 labeled form

Simonsson, Roger ; Stenhagen, Gunnar ; Ericsson, Cecilia ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, 30 May 2013, Vol.56(6), pp.334-337 [Peer Reviewed Journal]

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9
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PET Tracers To Study Clinically Relevant Hepatic Transporters

Testa, Andrea ; Zanda, Matteo ; Elmore, Charles S ; Sharma, Pradeep

Molecular pharmaceutics, 06 July 2015, Vol.12(7), pp.2203-16 [Peer Reviewed Journal]

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10
Synthesis of [13C5] and [carbonyl-14C]-5-chlorofuran-2-carboxylic acid
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Synthesis of [13C5] and [carbonyl-14C]-5-chlorofuran-2-carboxylic acid

Dorff, Peter N. ; Powell, Mark E. ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, 03/2011, Vol.54(3), pp.123-125 [Peer Reviewed Journal]

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11
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Editorial

Maxwell, Brad D. ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, 30 May 2016, Vol.59(6), pp.232-232 [Peer Reviewed Journal]

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12
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Evaluation of UV–HPLC and mass spectrometry methods for specific activity determination

Elmore, Charles S. ; Schenk, David J. ; Arent, Robert ; Kingston, Lee

Journal of Labelled Compounds and Radiopharmaceuticals, September 2014, Vol.57(11), pp.645-651 [Peer Reviewed Journal]

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13
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Synthesis of C‐14 labeled GABAA α2/α3 selective partial agonists and the investigation of late‐occurring and long‐circulating metabolites of GABAA receptor modulator AZD7325

Artelsmair, Markus ; Gu, Chungang ; Lewis, Richard J. ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, 15 May 2018, Vol.61(5), pp.415-426 [Peer Reviewed Journal]

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14
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New trends and applications in carboxylation for isotope chemistry

Bragg, Ryan A. ; Sardana, Malvika ; Artelsmair, Markus ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, November 2018, Vol.61(13), pp.934-948 [Peer Reviewed Journal]

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15
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Syntheses of the tricyclic cores of clozapine, dibenzo[b,f][1,4]thiazepin‐11(10H)‐one, and dibenzo[b,f][1,4]oxazepin‐11(10H)‐one in C‐14 labeled form by [ 14 C]carbonylation

Elmore, Charles S. ; Dorff, Peter N. ; Richard Heys, J.

Journal of Labelled Compounds and Radiopharmaceuticals, November 2010, Vol.53(13), pp.787-792 [Peer Reviewed Journal]

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16
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Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies

Isin, Emre M ; Elmore, Charles S ; Nilsson, Göran N ; Thompson, Richard A ; Weidolf, Lars

Chemical research in toxicology, 19 March 2012, Vol.25(3), pp.532-42 [Peer Reviewed Journal]

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17
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In vitro and in vivo metabolism of a selective δ-opioid receptor

Guo, Jian ; Gu, Chungang ; Zhou, Diansong ; Elmore, Charles S ; Bui, Khanh H ; Grimm, Scott W

Drug metabolism and disposition: the biological fate of chemicals, October 2011, Vol.39(10), pp.1883-94 [Peer Reviewed Journal]

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18
Synthesis of the NK3 receptor antagonist AZD2624 in C-14-, H-3- and C-13-labeled forms
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Synthesis of the NK3 receptor antagonist AZD2624 in C-14-, H-3- and C-13-labeled forms

Elmore, Charles S. ; Dorff, Peter N. ; Powell, Mark E. ; Hall, James E. ; Simpson, Thomas R.

Journal of Labelled Compounds and Radiopharmaceuticals, 05/15/2011, Vol.54(5), pp.239-246 [Peer Reviewed Journal]

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19
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Determining the isotopic abundance of a labeled compound by mass spectrometry and how correcting for natural abundance distribution using analogous data from the unlabeled compound leads to a systematic error

Schenk, David J. ; Lockley, William J. S. ; Elmore, Charles S. ; Hesk, Dave ; Roberts, Drew

Journal of Labelled Compounds and Radiopharmaceuticals, April 2016, Vol.59(4), pp.136-146 [Peer Reviewed Journal]

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20
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Synthesis of 2 C‐14 labeled cathepsin C inhibitors: The use of a cyanide to displace a Benzotriazole

Kingston, Lee ; Bergare, Jonas ; Lönn, Hans ; Ericsson, Cecilia ; Grönberg, Gunnar ; Chen, Song ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, 30 May 2017, Vol.60(6), pp.294-301 [Peer Reviewed Journal]

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21
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Metabolism of a G protein-coupled receptor modulator, including two major 1,2,4-oxadiazole ring-opened metabolites and a rearranged cysteine-piperazine adduct

Gu, Chungang ; Elmore, Charles S ; Lin, Jianrong ; Zhou, Diansong ; Luzietti, Rick ; Dorff, Peter ; Grimm, Scott W

Drug metabolism and disposition: the biological fate of chemicals, June 2012, Vol.40(6), pp.1151-63 [Peer Reviewed Journal]

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22
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Isotope labelling by reduction of nitriles: Application to the synthesis of isotopologues of tolmetin and celecoxib

Ellis‐Sawyer, Kate ; Bragg, Ryan A. ; Bushby, Nick ; Elmore, Charles S. ; Hickey, Michael J.

Journal of Labelled Compounds and Radiopharmaceuticals, April 2017, Vol.60(4), pp.213-220 [Peer Reviewed Journal]

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23
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The synthesis of tritium, carbon‐14 and stable isotope labelled selective estrogen receptor degraders

Bragg, Ryan A. ; Bushby, Nick ; Ericsson, Cecilia ; Kingston, Lee P. ; Ji, Hailong ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, September 2016, Vol.59(11), pp.454-461 [Peer Reviewed Journal]

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24
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Contribution of artifacts to N-methylated piperazine cyanide adduct formation in vitro from N-alkyl piperazine analogs

Zhang, Minli ; Resuello, Christina M ; Guo, Jian ; Powell, Mark E ; Elmore, Charles S ; Hu, Jun ; Vishwanathan, Karthick

Drug metabolism and disposition: the biological fate of chemicals, May 2013, Vol.41(5), pp.1023-34 [Peer Reviewed Journal]

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25
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Synthesis of [3H] and [2H6]AZD6642, an inhibitor of 5‐lipoxygenase activating protein (FLAP

Lindelöf, Åsa ; Ericsson, Cecilia ; Simonsson, Roger ; Nilsson, Göran ; Grönberg, Gunnar ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, July 2016, Vol.59(9), pp.340-345 [Peer Reviewed Journal]

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26
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The synthesis of a tritium, carbon‐14, and stable isotope‐labeled cathepsin C inhibitors

Allen, Paul ; Bragg, Ryan A. ; Caffrey, Moya ; Ericsson, Cecilia ; Hickey, Michael J. ; Kingston, Lee P. ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, February 2017, Vol.60(2), pp.124-129 [Peer Reviewed Journal]

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27
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[3H]Chiba‐1001(methyl‐SSR180711) has low in vitro binding affinity and poor in vivo selectivity to nicotinic alpha‐7 receptor in rodent brain

Ding, Min ; Ghanekar, Smita ; Elmore, Charles S. ; Zysk, John R. ; Werkheiser, Jennifer L. ; Lee, Chi‐Ming ; Liu, Jianwei ; Chhajlani, Vijay ; Maier, Donna L.

Synapse, April 2012, Vol.66(4), pp.315-322 [Peer Reviewed Journal]

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28
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14 Carbon monoxide made simple – novel approach to the generation, utilization, and scrubbing of 14 carbon monoxide

Lindhardt, Anders T. ; Simonssen, Roger ; Taaning, Rolf H. ; Gøgsig, Thomas M. ; Nilsson, Göran N. ; Stenhagen, Gunnar ; Elmore, Charles S. ; Skrydstrup, Troels

Journal of Labelled Compounds and Radiopharmaceuticals, September 2012, Vol.55(11), pp.411-418 [Peer Reviewed Journal]

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29
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Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds

Andersson, Jan D ; Pierson, M. Edward ; Finnema, Sjoerd J ; Gulyás, Balázs ; Heys, Richard ; Elmore, Charles S ; Farde, Lars ; Halldin, Christer

Nuclear Medicine and Biology, February 2011, Vol.38(2), pp.261-272 [Peer Reviewed Journal]

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30
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Synthesis of 1β‐hydroxydeoxycholic acid in H‐2 and unlabeled forms

Hayes, Martin A. ; Roberts, Ieuan ; Grönberg, Gunnar ; Lv, Kexin ; Lin, Baorui ; Bergare, Jonas ; Elmore, Charles S.

Journal of Labelled Compounds and Radiopharmaceuticals, April 2017, Vol.60(4), pp.221-229 [Peer Reviewed Journal]

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31
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Preclinical Evaluation of FLCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters

Testa, Andrea ; Dall'Angelo, Sergio ; Mingarelli, Marco ; Augello, Andrea ; Schweiger, Lutz ; Welch, Andrew ; Elmore, Charles S ; Dawson, Dana ; Sharma, Pradeep ; Zanda, Matteo

Contrast media & molecular imaging, 2018, Vol.2018, pp.3064751 [Peer Reviewed Journal]

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32
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Preparation of two D2 partial agonists in C‐14 and stable isotope labeled forms

Elmore, Charles S. ; Powell, Mark E. ; Xiong, Hui ; Wu, Ye ; Wang, Lijuan ; Saunders, David ; Urbanek, Rebecca A.

Journal of Labelled Compounds and Radiopharmaceuticals, July 2012, Vol.55(9), pp.359-365 [Peer Reviewed Journal]

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33
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[11C]AZ10419096 – a full antagonist PET radioligand for imaging brain 5-HT1B receptors

Lindberg, Anton ; Nag, Sangram ; Schou, Magnus ; Takano, Akihiro ; Matsumoto, Junya ; Amini, Nahid ; Elmore, Charles S ; Farde, Lars ; Pike, Victor W ; Halldin, Christer

Nuclear Medicine and Biology, November 2017, Vol.54, pp.34-40 [Peer Reviewed Journal]

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34
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Visible-Light-Enabled Aminocarbonylation of Unactivated Alkyl Iodides with Stoichiometric Carbon Monoxide for Application on Late-Stage Carbon Isotope Labeling

Sardana, Malvika ; Bergman, Joakim ; Ericsson, Cecilia ; Kingston, Lee P ; Schou, Magnus ; Dugave, Christophe ; Audisio, Davide ; Elmore, Charles S

The Journal of organic chemistry, 20 December 2019, Vol.84(24), pp.16076-16085 [Peer Reviewed Journal]

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35
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D2 receptor occupancy in conscious rat brain is not significantly distinguished with [ 3 H]‐MNPA, [ 3 H]‐(+)‐PHNO, and [ 3 H]‐raclopride

Peng, Teng ; Zysk, John ; Dorff, Peter ; Elmore, Charles S. ; Ström, Peter ; Malmquist, Jonas ; Ding, Min ; Tuke, David ; Werkheiser, Jennifer ; Widzowski, Dan ; Mrzljak, Ladislav ; Maier, Donna

Synapse, August 2010, Vol.64(8), pp.624-633 [Peer Reviewed Journal]

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36
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In vitro binding of a radio‐labeled positive allosteric modulator for metabotropic glutamate receptor subtype 5

Zysk, John R. ; Spear, Nathan ; Fieles, William ; Stein, Mark M. ; Sygowski, Linda S. ; King, Megan M. ; Hoesch, Valerie ; Hastings, Richard ; Brockel, Becky ; Do, Mylinh ; Ström, Peter ; Gadient, Reto ; Chhajlani, Vijay ; Elmore, Charles S. ; Maier, Donna L

Synapse, March 2013, Vol.67(3), pp.135-144 [Peer Reviewed Journal]

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37
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Synthesis of a delta opioid agonist in [2H6], [2H4], [11C], and [14C] labeled forms

Elmore, Charles S. ; Brush, Kelly ; Schou, Magnus ; Palmer, William ; Dorff, Peter N. ; Powell, Mark E. ; Hoesch, Valerie ; Hall, James E. ; Hudzik, Thomas ; Halldin, Christer ; Dantzman, Cathy L.

Journal of Labelled Compounds and Radiopharmaceuticals, December 2011, Vol.54(14), pp.847-854 [Peer Reviewed Journal]

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