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22 Results  for Everything (Includes Articles)

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1
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Molecular cloning of partial cDNAs for rabbit liver apolipoprotein B and the regulation of its mRNA levels by dietary cholesterol

Kroon, P A ; Demartino, J A ; Thompson, G M ; Chao, Y S

Proceedings of the National Academy of Sciences of the United States of America, July 1986, Vol.83(14), pp.5071-5 [Peer Reviewed Journal]

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Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist

Wisniewski, T ; Bayne, E ; Flanagan, J ; Shao, Q ; Wnek, R ; Matheravidathu, S ; Fischer, P ; Forrest, M J ; Peterson, L ; Song, X ; Yang, L ; Demartino, J A ; Struthers, M

Journal of immunological methods, 31 January 2010, Vol.352(1-2), pp.101-10 [Peer Reviewed Journal]

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Arginine 206 of the C5a receptor is critical for ligand recognition and receptor activation by C-terminal hexapeptide analogs

Demartino, J A ; Konteatis, Z D ; Siciliano, S J ; Van Riper, G ; Underwood, D J ; Fischer, P A ; Springer, M S

The Journal of biological chemistry, 07 July 1995, Vol.270(27), pp.15966-9 [Peer Reviewed Journal]

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Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses

Menetski, J ; Mistry, S ; Lu, M ; Mudgett, J S ; Ransohoff, R M ; Demartino, J A ; Macintyre, D E ; Abbadie, C

Neuroscience, 09 November 2007, Vol.149(3), pp.706-14 [Peer Reviewed Journal]

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5
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Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors

Weng, Y ; Siciliano, S J ; Waldburger, K E ; Sirotina-Meisher, A ; Staruch, M J ; Daugherty, B L ; Gould, S L ; Springer, M S ; Demartino, J A

The Journal of biological chemistry, 17 July 1998, Vol.273(29), pp.18288-91 [Peer Reviewed Journal]

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A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1

Siciliano, S J ; Kuhmann, S E ; Weng, Y ; Madani, N ; Springer, M S ; Lineberger, J E ; Danzeisen, R ; Miller, M D ; Kavanaugh, M P ; Demartino, J A ; Kabat, D

The Journal of biological chemistry, 22 January 1999, Vol.274(4), pp.1905-13 [Peer Reviewed Journal]

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7
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Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder

Di Salvo, J ; Nagabukuro, H ; Wickham, L A ; Abbadie, C ; Demartino, J A ; Fitzmaurice, A ; Gichuru, L ; Kulick, A ; Donnelly, M J ; Jochnowitz, N ; Hurley, A L ; Pereira, A ; Sanfiz, A ; Veronin, G ; Villa, K ; Woods, J ; Zamlynny, B ; Zycband, E ; Salituro, G M ; Frenkl

The Journal of pharmacology and experimental therapeutics, February 2017, Vol.360(2), pp.346-355 [Peer Reviewed Journal]

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8
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The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs

Demartino, J A ; Van Riper, G ; Siciliano, S J ; Molineaux, C J ; Konteatis, Z D ; Rosen, H ; Springer, M S

The Journal of biological chemistry, 20 May 1994, Vol.269(20), pp.14446-50 [Peer Reviewed Journal]

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9
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Prolyl 4-hydroxylase: molecular cloning and the primary structure of the alpha subunit from chicken embryo

Bassuk, J A ; Kao, W W ; Herzer, P ; Kedersha, N L ; Seyer, J ; Demartino, J A ; Daugherty, B L ; Mark, G E ; Berg, R A

Proceedings of the National Academy of Sciences of the United States of America, October 1989, Vol.86(19), pp.7382-6 [Peer Reviewed Journal]

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10
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Polymerase chain reaction facilitates the cloning, CDR-grafting, and rapid expression of a murine monoclonal antibody directed against the CD18 component of leukocyte integrins

Daugherty, B L ; Demartino, J A ; Law, M F ; Kawka, D W ; Singer, I I ; Mark, G E

Nucleic acids research, 11 May 1991, Vol.19(9), pp.2471-6 [Peer Reviewed Journal]

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11
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A receptor in pituitary and hypothalamus that functions in growth hormone release

Howard, A D ; Feighner, S D ; Cully, D F ; Arena, J P ; Liberator, P A ; Rosenblum, C I ; Hamelin, M ; Hreniuk, D L ; Palyha, O C ; Anderson, J ; Paress, P S ; Diaz, C ; Chou, M ; Liu, K K ; Mckee, K K ; Pong, S S ; Chaung, L Y ; Elbrecht, A ; Dashkevicz, M ; Heavens, R ; Rigby, M ; Sirinathsinghji, D J ; Dean, D C ; Melillo, D G ; Patchett, A A ; Nargund, R ; Griffin, P R ; Demartino, J A ; Gupta, S K ; Schaeffer, J M ; Smith, R G ; Van Der Ploeg, L H

Science (New York, N.Y.), 16 August 1996, Vol.273(5277), pp.974-7 [Peer Reviewed Journal]

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12
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The CXCR4 agonist ligand stromal derived factor-1 maintains high affinity for receptors in both Galpha(i)-coupled and uncoupled states

Di Salvo, J ; Koch, G E ; Johnson, K E ; Blake, A D ; Daugherty, B L ; Demartino, J A ; Sirotina-Meisher, A ; Liu, Y ; Springer, M S ; Cascieri, M A ; Sullivan, K A

European journal of pharmacology, 08 December 2000, Vol.409(2), pp.143-54 [Peer Reviewed Journal]

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13
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1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 1: discovery of the pyrrolidine scaffold and determination of its stereochemical requirements

Hale, J J ; Budhu, R J ; Mills, S G ; Maccoss, M ; Malkowitz, L ; Siciliano, S ; Gould, S L ; Demartino, J A ; Springer, M S

Bioorganic & medicinal chemistry letters, 04 June 2001, Vol.11(11), pp.1437-40 [Peer Reviewed Journal]

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14
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Cloning, expression, and characterization of the human eosinophil eotaxin receptor

Daugherty, B L ; Siciliano, S J ; Demartino, J A ; Malkowitz, L ; Sirotina, A ; Springer, M S

The Journal of experimental medicine, 01 May 1996, Vol.183(5), pp.2349-54 [Peer Reviewed Journal]

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15
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Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure-activity relationships for 1-N-(methyl)-N-(phenylsulfonyl)amino-2-(phenyl)-4-(4-(N-(alkyl)-N-(benzyloxycarbonyl)amino)piperidin-1-yl)butanes

Finke, P E ; Oates, B ; Mills, S G ; Maccoss, M ; Malkowitz, L ; Springer, M S ; Gould, S L ; Demartino, J A ; Carella, A ; Carver, G ; Holmes, K ; Danzeisen, R ; Hazuda, D ; Kessler, J ; Lineberger, J ; Miller, M ; Schleif, W A ; Emini, E A

Bioorganic & medicinal chemistry letters, 17 September 2001, Vol.11(18), pp.2475-9 [Peer Reviewed Journal]

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16
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A single amino acid substitution in a common African allele of the CD4 molecule ablates binding of the monoclonal antibody, OKT4

Lederman, S ; Demartino, J A ; Daugherty, B L ; Foeldvari, I ; Yellin, M J ; Cleary, A M ; Berkowitz, N ; Lowy, I ; Braunstein, N S ; Mark, G E

Molecular immunology, November 1991, Vol.28(11), pp.1171-81 [Peer Reviewed Journal]

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17
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The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins

Hill, C M ; Kwon, D ; Jones, M ; Davis, C B ; Marmon, S ; Daugherty, B L ; Demartino, J A ; Springer, M S ; Unutmaz, D ; Littman, D R

Virology, 01 September 1998, Vol.248(2), pp.357-71 [Peer Reviewed Journal]

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18
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Design, synthesis, and SAR of heterocycle-containing antagonists of the human CCR5 receptor for the treatment of HIV-1 infection

Kim, D ; Wang, L ; Caldwell, C G ; Chen, P ; Finke, P E ; Oates, B ; Maccoss, M ; Mills, S G ; Malkowitz, L ; Gould, S L ; Demartino, J A ; Springer, M S ; Hazuda, D ; Miller, M ; Kessler, J ; Danzeisen, R ; Carver, G ; Carella, A ; Holmes, K ; Lineberger

Bioorganic & medicinal chemistry letters, 17 December 2001, Vol.11(24), pp.3103-6 [Peer Reviewed Journal]

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19
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Discovery of human CCR5 antagonists containing hydantoins for the treatment of HIV-1 infection

Kim, D ; Wang, L ; Caldwell, C G ; Chen, P ; Finke, P E ; Oates, B ; Maccoss, M ; Mills, S G ; Malkowitz, L ; Gould, S L ; Demartino, J A ; Springer, M S ; Hazuda, D ; Miller, M ; Kessler, J ; Danzeisen, R ; Carver, G ; Carella, A ; Holmes, K ; Lineberger

Bioorganic & medicinal chemistry letters, 17 December 2001, Vol.11(24), pp.3099-102 [Peer Reviewed Journal]

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20
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Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 2: structure-activity relationships for substituted 2-Aryl-1-N-(methyl)-N-(phenylsulfonyl)amino-4-(piperidin-1-yl)butanes

Finke, P E ; Meurer, L C ; Oates, B ; Mills, S G ; Maccoss, M ; Malkowitz, L ; Springer, M S ; Daugherty, B L ; Gould, S L ; Demartino, J A ; Siciliano, S J ; Carella, A ; Carver, G ; Holmes, K ; Danzeisen, R ; Hazuda, D ; Kessler, J ; Lineberger, J ; Miller, M ; Schleif

Bioorganic & medicinal chemistry letters, 22 January 2001, Vol.11(2), pp.265-70 [Peer Reviewed Journal]

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21
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CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells

Singer, I I ; Scott, S ; Kawka, D W ; Chin, J ; Daugherty, B L ; Demartino, J A ; Disalvo, J ; Gould, S L ; Lineberger, J E ; Malkowitz, L ; Miller, M D ; Mitnaul, L ; Siciliano, S J ; Staruch, M J ; Williams, H R ; Zweerink, H J ; Springer, M S

Journal of virology, April 2001, Vol.75(8), pp.3779-90 [Peer Reviewed Journal]

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22
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1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2: lead optimization affording selective, orally bioavailable compounds with potent anti-HIV activity

Hale, J J ; Budhu, R J ; Holson, E B ; Finke, P E ; Oates, B ; Mills, S G ; Maccoss, M ; Gould, S L ; Demartino, J A ; Springer, M S ; Siciliano, S ; Malkowitz, L ; Schleif, W A ; Hazuda, D ; Miller, M ; Kessler, J ; Danzeisen, R ; Holmes, K ; Lineberger, J ; Carella

Bioorganic & medicinal chemistry letters, 22 October 2001, Vol.11(20), pp.2741-5 [Peer Reviewed Journal]

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