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15 Results  for Everything (Includes Articles)

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1,3,8-Triazaspiro4.5decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia

Vachal, Petr ; Miao, Shouwu ; Pierce, Joan M ; Guiadeen, Deodial ; Colandrea, Vincent J ; Wyvratt, Matthew J ; Salowe, Scott P ; Sonatore, Lisa M ; Milligan, James A ; Hajdu, Richard ; Gollapudi, Anantha ; Keohane, Carol A ; Lingham, Russell B ; Mandala, Suzanne M ; Demartino, Julie A ; Tong, Xinchun ; Wolff, Michael ; Steinhuebel, Dietrich ; Kieczykowski, Gerard R ; Fleitz

Journal of medicinal chemistry, 12 April 2012, Vol.55(7), pp.2945-59 [Peer Reviewed Journal]

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Synthesis and regioselective alkylation of 1,6- and 1,7-naphthyridines

Colandrea, Vincent J ; Naylor, Elizabeth M

Tetrahedron Letters, 2000, Vol.41(42), pp.8053-8057 [Peer Reviewed Journal]

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Synthesis of the mitomycin and FR900482 ring systems via dimethyldioxirane oxidation

Colandrea, Vincent J ; Rajaraman, Shanthi ; Jimenez, Leslie S

Organic letters, 20 March 2003, Vol.5(6), pp.785-7 [Peer Reviewed Journal]

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Reactivity and rearrangements of dialkyl- and diarylvinylsulfonium salts with indole-2- and pyrrole-2-carboxaldehydes

Wang, Yufeng ; Zhang, Weihong ; Colandrea, Vincent J ; Jimenez, Leslie S

Tetrahedron, 1999, Vol.55(35), pp.10659-10672 [Peer Reviewed Journal]

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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor

Neelamkavil, Santhosh F ; Agrawal, Sony ; Bara, Thomas ; Bennett, Chad ; Bhat, Sathesh ; Biswas, Dipshikha ; Brockunier, Linda ; Buist, Nicole ; Burnette, Duane ; Cartwright, Mark ; Chackalamannil, Samuel ; Chase, Robert ; Chelliah, Mariappan ; Chen, Austin ; Clasby, Martin ; Colandrea, Vincent J ; Davies, Ian W ; Eagen, Keith ; Guo, Zhuyan ; Han

ACS medicinal chemistry letters, 14 January 2016, Vol.7(1), pp.111-6 [Peer Reviewed Journal]

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Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia

Liu, Ping ; Wang, Liping ; Dubois, Byron G ; Colandrea, Vincent J ; Liu, Rongqiang ; Cai, Jiaqiang ; Du, Xiaoxing ; Quan, Weiguo ; Morris, William ; Bai, Jianwu ; Bishwokarma, Bimjhana ; Cheng, Mangeng ; Piesvaux, Jennifer ; Ray, Kallol ; Alpert, Carla ; Chiu, Chi-Sung ; Zielstorff, Mark ; Metzger, Joseph M ; Yang, Liming ; Leung

ACS medicinal chemistry letters, 13 December 2018, Vol.9(12), pp.1193-1198 [Peer Reviewed Journal]

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Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach

Wilson, Jonathan E ; Kurukulasuriya, Ravi ; Reibarkh, Mikhail ; Reiter, Maud ; Zwicker, Aaron ; Zhao, Kake ; Zhang, Fengqi ; Anand, Rajan ; Colandrea, Vincent J ; Cumiskey, Anne-Marie ; Crespo, Alejandro ; Duffy, Ruth A ; Murphy, Beth Ann ; Mitra, Kaushik ; Johns, Douglas G ; Duffy, Joseph L ; Vachal, Petr

ACS medicinal chemistry letters, 10 March 2016, Vol.7(3), pp.261-5 [Peer Reviewed Journal]

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Improved synthesis of aryl 1,1-dimethylpropargyl ethers

Godfrey, Jollie D ; Mueller, Richard H ; Sedergran, Thomas C ; Soundararajan, Nachimuthu ; Colandrea, Vincent J

Tetrahedron Letters, 1994, Vol.35(35), pp.6405-6408 [Peer Reviewed Journal]

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Synthesis and evaluation of N-[(1 S,2 S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists

Du, Wu ; Jewell, James P ; Lin, Linus S ; Colandrea, Vincent J ; Xiao, Jing C ; Lao, Julie ; Shen, Chun-Pyn ; Bateman, Thomas J ; Reddy, Vijay B.G ; Ha, Sookhee N ; Shah, Shrenik K ; Fong, Tung M ; Hale, Jeffrey J ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(17), pp.5195-5199 [Peer Reviewed Journal]

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Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists

Armstrong, Helen E ; Galka, Amy ; Lin, Linus S ; Lanza, Thomas J ; Jewell, James P ; Shah, Shrenik K ; Guthikonda, Ravi ; Truong, Quang ; Chang, Linda L ; Quaker, Grace ; Colandrea, Vincent J ; Tong, Xinchun ; Wang, Junying ; Xu, Sherry ; Fong, Tung M ; Shen, Chun-Pyn ; Lao, Julie ; Chen, Jing ; Shearman, Lauren P ; Stribling, D. Sloan

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(8), pp.2184-2187 [Peer Reviewed Journal]

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2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists

Colandrea, Vincent J ; Legiec, Irene E ; Huo, Pei ; Yan, Lin ; Hale, Jeffrey J ; Mills, Sander G ; Bergstrom, James ; Card, Deborah ; Chebret, Gary ; Hajdu, Richard ; Keohane, Carol Ann ; Milligan, James A ; Rosenbach, Mark J ; Shei, Gan-Ju ; Mandala, Suzanne M

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(11), pp.2905-2908 [Peer Reviewed Journal]

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The pharmacokinetics of a thiazole benzenesulfonamide beta 3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: improving oral bioavailability

Stearns, Ralph A ; Miller, Randy R ; Tang, Wei ; Kwei, Gloria Y ; Tang, Frank S ; Mathvink, Robert J ; Naylor, Elizabeth M ; Chitty, Dawn ; Colandrea, Vincent J ; Weber, Ann E ; Colletti, Adria E ; Strauss, John R ; Keohane, Carol Ann ; Feeney, William P ; Iliff, Susan A ; Chiu, Shuet-Hing Lee

Drug metabolism and disposition: the biological fate of chemicals, July 2002, Vol.30(7), pp.771-7 [Peer Reviewed Journal]

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3-pyridylethanolamines: Potent and selective human β 3 adrenergic receptor agonists

Naylor, Elizabeth M ; Colandrea, Vincent J ; Candelore, Mari R ; Cascieri, Margaret A ; Colwell, Lawrence F ; Deng, Liping ; Feeney, William P ; Forrest, Michael J ; Hom, Gary J ; Euan Macintyre, D ; Strader, Catherine D ; Tota, Laurie ; Wang, Pei-Ran ; Wyvratt, Matthew J ; Fisher, Michael H ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 1998, Vol.8(21), pp.3087-3092 [Peer Reviewed Journal]

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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective β 3 adrenergic receptor agonist antiobesity agents

Biftu, Tesfaye ; Feng, Dennis D ; Liang, Gui-Bai ; Kuo, Howard ; Qian, Xiaoxia ; Naylor, Elizabeth M ; Colandrea, Vincent J ; Candelore, Mari R ; Cascieri, Margaret A ; Colwell, Lawrence F ; Forrest, Michael J ; Hom, Gary J ; Macintyre, D.Euan ; Stearns, Ralph A ; Strader, Catherine D ; Wyvratt, Matthew J ; Fisher, Michael H ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2000, Vol.10(13), pp.1431-1434 [Peer Reviewed Journal]

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Human β3 andrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides

Naylor, Elizabeth M ; Parmee, Emma R ; Colandrea, Vincent J ; Perkins, Leroy ; Brockunier, Linda ; Candelore, Mari R ; Cascieri, Margaret A ; Colwell, Lawrence F ; Deng, Liping ; Feeney, William P ; Forrest, Michael J ; Hom, Gary J ; Macintyre, D.Euan ; Strader, Catherine D ; Tota, Laurie ; Wang, Pei-Ran ; Wyvratt, Matthew J ; Fisher, Michael H ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 1999, Vol.9(5), pp.755-758 [Peer Reviewed Journal]

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