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24 Results  for Everything (Includes Articles)

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1
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Highly regioselective palladium-catalyzed direct arylation of oxazole at C-2 or C-5 with aryl bromides, chlorides, and triflates

Strotman, Neil A ; Chobanian, Harry R ; Guo, Yan ; He, Jiafang ; Wilson, Jonathan E

Organic letters, 20 August 2010, Vol.12(16), pp.3578-81 [Peer Reviewed Journal]

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Synthesis of novel 2-azabicyclo[3.1.1]heptane-5-carboxylic acid

He, Shuwen ; Hao, Jinsong ; Ashley, Eric R ; Chobanian, Harry R ; Pio, Barbara ; Colletti, Steven L ; Miller, Michael

Tetrahedron Letters, 16 March 2016, Vol.57(11), pp.1268-1269 [Peer Reviewed Journal]

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Synthesis of a lactone diastereomer of the cembranolide uprolide D

Marshall, James A ; Griot, Céline A ; Chobanian, Harry R ; Myers, William H

Organic letters, 01 October 2010, Vol.12(19), pp.4328-31 [Peer Reviewed Journal]

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4
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Catalyst-controlled regioselective Suzuki couplings at both positions of dihaloimidazoles, dihalooxazoles, and dihalothiazoles

Strotman, Neil A ; Chobanian, Harry R ; He, Jiafang ; Guo, Yan ; Dormer, Peter G ; Jones, Christina M ; Steves, Janelle E

The Journal of organic chemistry, 05 March 2010, Vol.75(5), pp.1733-9 [Peer Reviewed Journal]

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5
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Synthesis of 2,5-disubstituted tetrahydrofurans by stereospecific elimination-cyclization of 1-iodomethyl-1,5-bis-epoxides

Marshall, James A ; Chobanian, Harry R

Organic letters, 29 May 2003, Vol.5(11), pp.1931-3 [Peer Reviewed Journal]

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The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization

Chobanian, Harry R ; Guo, Yan ; Liu, Ping ; Lanza, Thomas J ; Chioda, Marc ; Chang, Linda ; Kelly, Theresa M ; Kan, Yanqing ; Palyha, Oksana ; Guan, Xiao-Ming ; Marsh, Donald J ; Metzger, Joseph M ; Raustad, Katie ; Wang, Sheng-Ping ; Strack, Alison M ; Gorski, Judith N ; Miller, Randy ; Pang, Jianmei ; Lyons, Kathy ; Dragovic, Jasminka

Bioorganic & Medicinal Chemistry, 01 May 2012, Vol.20(9), pp.2845-2849 [Peer Reviewed Journal]

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7
Additions of Enantioenriched Allenylzinc and Indium Reagents to Lactic Aldehyde Ethers
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Additions of Enantioenriched Allenylzinc and Indium Reagents to Lactic Aldehyde Ethers

Marshall, James A. ; Chobanian, Harry R.

The Journal of Organic Chemistry, 12/2000, Vol.65(24), pp.8357-8360 [Peer Reviewed Journal]

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8
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A facile microwave-assisted palladium-catalyzed cyanation of aryl chlorides

Chobanian, Harry R ; Fors, Brett P ; Lin, Linus S

Tetrahedron Letters, 2006, Vol.47(19), pp.3303-3305 [Peer Reviewed Journal]

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9
Coupling of AlkynylTMS Derivatives with Vinylic Iodides. An Efficient Route to 1,3-Enynes and Dienes
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Coupling of AlkynylTMS Derivatives with Vinylic Iodides. An Efficient Route to 1,3-Enynes and Dienes

Marshall, James A. ; Chobanian, Harry R. ; Yanik, Mathew M.

Organic Letters, 12/2001, Vol.3(25), pp.4107-4110 [Peer Reviewed Journal]

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10
Lipase-Mediated Resolution of 4-TMS-3-butyn-2-ol and Use of the Mesylate Derivatives as a Precursor to a Highly Stereoselective Chiral Allenylindium Reagent
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Lipase-Mediated Resolution of 4-TMS-3-butyn-2-ol and Use of the Mesylate Derivatives as a Precursor to a Highly Stereoselective Chiral Allenylindium Reagent

Marshall, James A. ; Chobanian, Harry R. ; Yanik, Mathew M.

Organic Letters, 10/2001, Vol.3(21), pp.3369-3372 [Peer Reviewed Journal]

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11
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GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent

Pachanski, Michele J ; Kirkland, Melissa E ; Kosinski, Daniel T ; Mane, Joel ; Cheewatrakoolpong, Boonlert ; Xue, Jiyan ; Szeto, Daphne ; Forrest, Gail ; Miller, Corin ; Bunzel, Michelle ; Plummer, Christopher W ; Chobanian, Harry R ; Miller, Michael W ; Souza, Sarah ; Thomas-Fowlkes, Brande S ; Ogawa, Aimie M ; Weinglass, Adam B ; Di Salvo, Jerry ; Li, Xiaoyan ; Feng

PloS one, 2017, Vol.12(10), pp.e0186033 [Peer Reviewed Journal]

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12
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A facile, microwave-assisted, palladium-catalyzed arylation of acetone

Chobanian, Harry R ; Liu, Ping ; Chioda, Marc D ; Guo, Yan ; Lin, Linus S

Tetrahedron Letters, 2007, Vol.48(7), pp.1213-1216 [Peer Reviewed Journal]

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13
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A one-pot synthesis of 3-substituted-5-carbonylmethyl-1,2,4-oxadiazoles from β-keto esters and amidoximes under solvent-free conditions

Du, Wu ; Truong, Quang ; Qi, Hongbo ; Guo, Yan ; Chobanian, Harry R ; Hagmann, William K ; Hale, Jeffrey J

Tetrahedron Letters, 2007, Vol.48(13), pp.2231-2235 [Peer Reviewed Journal]

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14
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Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists

Lo, Michael M.-C ; Chobanian, Harry R ; Palyha, Oksana ; Kan, Yanqing ; Kelly, Theresa M ; Guan, Xiao-Ming ; Reitman, Marc L ; Dragovic, Jasminka ; Lyons, Kathryn A ; Nargund, Ravi P ; Lin, Linus S

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(7), pp.2040-2043 [Peer Reviewed Journal]

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15
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Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality

Liu, Ping ; Lanza, Thomas J ; Chioda, Marc ; Jones, Carrie ; Chobanian, Harry R ; Guo, Yan ; Chang, Linda ; Kelly, Theresa M ; Kan, Yanqing ; Palyha, Oksana ; Guan, Xiao-Ming ; Marsh, Donald J ; Metzger, Joseph M ; Ramsay, Katie ; Wang, Sheng-Ping ; Strack, Alison M ; Miller, Randy ; Pang, Jianmei ; Lyons, Kathy ; Dragovic

ACS medicinal chemistry letters, 08 December 2011, Vol.2(12), pp.933-7 [Peer Reviewed Journal]

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16
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Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity

Chobanian, Harry R ; Guo, Yan ; Liu, Ping ; Chioda, Marc ; Lanza, Thomas J ; Chang, Linda ; Kelly, Theresa M ; Kan, Yanqing ; Palyha, Oksana ; Guan, Xiao-Ming ; Marsh, Donald J ; Metzger, Joseph M ; Gorski, Judith N ; Raustad, Kate ; Wang, Sheng-Ping ; Strack, Alison M ; Miller, Randy ; Pang, Jianmei ; Madeira, Maria ; Lyons

ACS medicinal chemistry letters, 08 March 2012, Vol.3(3), pp.252-6 [Peer Reviewed Journal]

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17
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The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics

Chobanian, Harry R ; Guo, Yan ; Pio, Barbara ; Tang, Haifeng ; Teumelsan, Nardos ; Clements, Matthew ; Frie, Jessica ; Ferguson, Ronald ; Guo, Zach ; Thomas-Fowlkes, Brande S ; Felix, John P ; Liu, Jessica ; Kohler, Martin ; Priest, Birgit ; Hampton, Caryn ; Pai, Lee-Yuh ; Corona, Aaron ; Metzger, Joseph ; Tong, Vincent ; Joshi, Elizabeth M

Bioorganic & Medicinal Chemistry Letters, 15 February 2017, Vol.27(4), pp.1109-1114 [Peer Reviewed Journal]

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18
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Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs

Chen, Helen Y ; Plummer, Christopher W ; Xiao, Dong ; Chobanian, Harry R ; Demong, Duane ; Miller, Michael ; Trujillo, Maria E ; Kirkland, Melissa ; Kosinski, Daniel ; Mane, Joel ; Pachanski, Michele ; Cheewatrakoolpong, Boonlert ; Di Salvo, Jerry ; Thomas-Fowlkes, Brande ; Souza, Sarah ; Tatosian, Daniel A ; Chen, Qing ; Hafey, Michael J ; Houle, Robert ; Nolting

ACS medicinal chemistry letters, 12 July 2018, Vol.9(7), pp.685-690 [Peer Reviewed Journal]

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19
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Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement

Chobanian, Harry R ; Pio, Barbara ; Guo, Yan ; Shen, Hong ; Huffman, Mark A ; Madeira, Maria ; Salituro, Gino ; Terebetski, Jenna L ; Ormes, James ; Jochnowitz, Nina ; Hoos, Lizbeth ; Zhou, Yuchen ; Lewis, Dale ; Hawes, Brian ; Mitnaul, Lyndon ; O'Neill, Kim ; Ellsworth, Kenneth ; Wang, Liangsu ; Biftu

ACS medicinal chemistry letters, 14 May 2015, Vol.6(5), pp.553-7 [Peer Reviewed Journal]

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20
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Differentiation of Deprotonated Acyl-, -, and -Glucuronide Drug Metabolites by Using Tandem Mass Spectrometry Based on Gas-Phase Ion-Molecule Reactions Followed by Collision-Activated Dissociation

Niyonsaba, Edouard ; Easton, Mckay W ; Feng, Erlu ; Yu, Zaikuan ; Zhang, Zhoupeng ; Sheng, Huaming ; Kong, John ; Easterling, Leah F ; Milton, Jacob ; Chobanian, Harry R ; Deprez, Nicholas R ; Cancilla, Mark T ; Kilaz, Gozdem ; Kenttämaa, Hilkka I

Analytical chemistry, 03 September 2019, Vol.91(17), pp.11388-11396 [Peer Reviewed Journal]

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21
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Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain

Chobanian, Harry R ; Guo, Yan ; Liu, Ping ; Chioda, Marc D ; Fung, Selena ; Lanza, Thomas J ; Chang, Linda ; Bakshi, Raman K ; Dellureficio, James P ; Hong, Qingmei ; Mclaughlin, Mark ; Belyk, Kevin M ; Krska, Shane W ; Makarewicz, Amanda K ; Martel, Elliot J ; Leone, Joseph F ; Frey, Lisa ; Karanam, Bindhu ; Madeira, Maria ; Alvaro

ACS medicinal chemistry letters, 12 June 2014, Vol.5(6), pp.717-21 [Peer Reviewed Journal]

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22
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Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Lu, Jun ; Byrne, Noel ; Wang, John ; Bricogne, Gerard ; Brown, Frank K ; Chobanian, Harry R ; Colletti, Steven L ; Di Salvo, Jerry ; Thomas-Fowlkes, Brande ; Guo, Yan ; Hall, Dawn L ; Hadix, Jennifer ; Hastings, Nicholas B ; Hermes, Jeffrey D ; Ho, Thu ; Howard, Andrew D ; Josien, Hubert ; Kornienko, Maria ; Lumb, Kevin J ; Miller

Nature structural & molecular biology, July 2017, Vol.24(7), pp.570-577 [Peer Reviewed Journal]

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23
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Bioactivation of GPR40 Agonist MK-8666: Formation of Protein Adducts in Vitro from Reactive Acyl Glucuronide and Acyl CoA Thioester

Shang, Jackie ; Tschirret-Guth, Richard ; Cancilla, Mark ; Samuel, Koppara ; Chen, Qing ; Chobanian, Harry R ; Thomas, Ann ; Tong, Wei ; Josien, Hubert ; Buevich, Alexei V ; Mitra, Kaushik

Chemical research in toxicology, 21 January 2020, Vol.33(1), pp.191-201 [Peer Reviewed Journal]

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24
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Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs

Pio, Barbara ; Chobanian, Harry R ; Guo, Yan ; Josien, Hubert ; Hagmann, William K ; Miller, Michael ; Trujillo, Maria E ; Kirkland, Melissa ; Kosinski, Daniel ; Mane, Joel ; Pachanski, Michele ; Cheewatrakoolpong, Boonlert ; Ashley, Eric ; Orr, Robert ; Wright, Michael J ; Bugianesi, Randal ; Souza, Sarah ; Zhang, Xiaoping ; Di Salvo, Jerry ; Weinglass, Adam B

Bioorganic & Medicinal Chemistry Letters, 15 July 2019, Vol.29(14), pp.1842-1848 [Peer Reviewed Journal]

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