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1
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Identification and Characterization of Pectenotoxin (PTX) 4 and PTX7 as Spiroketal Stereoisomers of Two Previously Reported Pectenotoxins

Sasaki, Katsunori ; Wright, Jeffrey L. C ; Yasumoto, Takeshi

The Journal of organic chemistry, 17 April 1998, Vol.63(8), pp.2475-2480 [Peer Reviewed Journal]

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2
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Total syntheses and endoplasmic reticulum stress suppressive activities of hericenes A−C and their derivatives

Kobayashi, Shoji ; Hamada, Yoshiki ; Yasumoto, Takeshi ; Hashino, Yuuki ; Masuyama, Araki ; Nagai, Kaoru

Tetrahedron Letters, 02 May 2018, Vol.59(18), pp.1733-1736 [Peer Reviewed Journal]

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Detailed LC-MS/MS analysis of ciguatoxins revealing distinct regional and species characteristics in fish and causative alga from the Pacific

Yogi, Kentaro ; Oshiro, Naomasa ; Inafuku, Yasuo ; Hirama, Masahiro ; Yasumoto, Takeshi

Analytical chemistry, 01 December 2011, Vol.83(23), pp.8886-91 [Peer Reviewed Journal]

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4
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Cyclic Guanidine Compounds from Toxic Newts Support the Hypothesis that Tetrodotoxin is Derived from a Monoterpene

Kudo, Yuta ; Yasumoto, Takeshi ; Mebs, Dietrich ; Cho, Yuko ; Konoki, Keiichi ; Yotsu‐Yamashita, Mari

Angewandte Chemie International Edition, 18 July 2016, Vol.55(30), pp.8728-8731 [Peer Reviewed Journal]

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5
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Gambieroxide, a novel epoxy polyether compound from the dinoflagellate Gambierdiscus toxicus GTP2 strain

Watanabe, Ryuichi ; Uchida, Hajime ; Suzuki, Toshiyuki ; Matsushima, Ryoji ; Nagae, Mika ; Toyohara, Yoshikazu ; Satake, Masayuki ; Oshima, Yasukatsu ; Inoue, Akio ; Yasumoto, Takeshi

Tetrahedron, 02 December 2013, Vol.69(48), pp.10299-10303 [Peer Reviewed Journal]

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6
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Quantification of Representative Ciguatoxins in the Pacific Using Quantitative Nuclear Magnetic Resonance Spectroscopy

Kato, Tsuyoshi ; Yasumoto, Takeshi

Marine Drugs, 2017, Vol.15(10), p.309 [Peer Reviewed Journal]

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7
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C5–C10 Directly Bonded Tetrodotoxin Analogues: Possible Biosynthetic Precursors of Tetrodotoxin From Newts

Kudo, Yuta ; Yamashita, Yoko ; Mebs, Dietrich ; Cho, Yuko ; Konoki, Keiichi ; Yasumoto, Takeshi ; Yotsu‐Yamashita, Mari

Angewandte Chemie International Edition, 22 December 2014, Vol.53(52), pp.14546-14549 [Peer Reviewed Journal]

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8
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Phylogeography of Ostreopsis along West Pacific Coast, with Special Reference to a Novel Clade from Japan (Phylogeography of Ostreopsis along W Pacific Coast)

Sato, Shinya ; Nishimura, Tomohiro ; Uehara, Keita ; Sakanari, Hiroshi ; Tawong, Wittaya ; Hariganeya, Naohito ; Smith, Kirsty ; Rhodes, Lesley ; Yasumoto, Takeshi ; Taira, Yosuke ; Suda, Shoichiro ; Yamaguchi, Haruo ; Adachi, Masao Neilan, Brett (Editor)

PLoS ONE, 2011, Vol.6(12), p.e27983 [Peer Reviewed Journal]

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9
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Chemical, molecular, and eco-toxicological investigation of Ostreopsis sp. from Cyprus Island: structural insights into four new ovatoxins by LC-HRMS/MS

Tartaglione, Luciana ; Mazzeo, Antonia ; Dell’Aversano, Carmela ; Forino, Martino ; Giussani, Valentina ; Capellacci, Samuela ; Penna, Antonella ; Asnaghi, Valentina ; Faimali, Marco ; Chiantore, Mariachiara ; Yasumoto, Takeshi ; Ciminiello, Patrizia

Analytical and Bioanalytical Chemistry, 2016, Vol.408(3), pp.915-932 [Peer Reviewed Journal]

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Chemical, molecular, and eco-toxicological investigation of Ostreopsis sp. from Cyprus Island: structural insights into four new ovatoxins by LC-HRMS/MS

Tartaglione, Luciana ; Mazzeo, Antonia ; Dell'Aversano, Carmela ; Forino, Martino ; Giussani, Valentina ; Capellacci, Samuela ; Penna, Antonella ; Asnaghi, Valentina ; Faimali, Marco ; Chiantore, Mariachiara ; Yasumoto, Takeshi ; Ciminiello, Patrizia

Analytical and bioanalytical chemistry, January 2016, Vol.408(3), pp.915-32 [Peer Reviewed Journal]

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11
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Genetic Diversity and Distribution of the Ciguatera-Causing Dinoflagellate Gambierdiscus spp. (Dinophyceae) in Coastal Areas of Japan

Nishimura, Tomohiro ; Sato, Shinya ; Tawong, Wittaya ; Sakanari, Hiroshi ; Uehara, Keita ; Shah, Md Mahfuzur Rahman ; Suda, Shoichiro ; Yasumoto, Takeshi ; Taira, Yohsuke ; Yamaguchi, Haruo ; Adachi, Masao Neilan, Brett (editor)

PLoS ONE, 2013, Vol.8(4) [Peer Reviewed Journal]

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12
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New Insights on Cytological and Metabolic Features of Ostreopsis cf. ovata Fukuyo (Dinophyceae): A Multidisciplinary Approach

Honsell, Giorgio ; Bonifacio, Alois ; De Bortoli, Marco ; Penna, Antonella ; Battocchi, Cecilia ; Ciminiello, Patrizia ; Dell’aversano, Carmela ; Fattorusso, Ernesto ; Sosa, Silvio ; Yasumoto, Takeshi ; Tubaro, Aurelia Lin, Senjie (editor)

PLoS ONE, 2013, Vol.8(2) [Peer Reviewed Journal]

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13
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Structural elucidation of palytoxin analogs produced by the dinoflagellate Ostreopsis ovata IK2 strain by complementary use of positive and negative ion liquid chromatography/quadrupole time‐of‐flight mass spectrometry

Uchida, Hideaki ; Taira, Yohsuke ; Yasumoto, Takeshi

Rapid Communications in Mass Spectrometry, 15 September 2013, Vol.27(17), pp.1999-2008 [Peer Reviewed Journal]

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14
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Anti-neoplastic effects of fucoxanthin and its deacetylated product, fucoxanthinol, on Burkitt’s and Hodgkin’s lymphoma cells

Tafuku, Senji ; Ishikawa, Chie ; Yasumoto, Takeshi ; Mori, Naoki

Oncology Reports, 2012, Vol.28(4), pp.1512-1518 [Peer Reviewed Journal]

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15
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Biooxidation of Ciguatoxins Leads to Species-Specific Toxin Profiles

Ikehara, Tsuyoshi ; Kuniyoshi, Kyoko ; Oshiro, Naomasa ; Yasumoto, Takeshi Vetter, Irina (editor)

Toxins, 2017, Vol.9(7) [Peer Reviewed Journal]

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16
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Different responses of primary normal human hepatocytes and human hepatoma cells toward cyanobacterial hepatotoxin microcystin-LR

Ikehara, Tsuyoshi ; Nakashima, Junichi ; Nakashima, Shihoko ; Yasumoto, Takeshi

Toxicon, October 2015, Vol.105, pp.4-9 [Peer Reviewed Journal]

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17
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Simple structural elucidation of ostreocin‐B, a new palytoxin congener isolated from the marine dinoflagellate Ostreopsis siamensis, using complementary positive and negative ion liquid chromatography/quadrupole time‐of‐flight mass spectrometry

Terajima, Takehito ; Uchida, Hideaki ; Abe, Naoki ; Yasumoto, Takeshi

Rapid Communications in Mass Spectrometry, 30 June 2018, Vol.32(12), pp.1001-1007 [Peer Reviewed Journal]

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18
Structures and Partial Stereochemical Assignments for Prymnesin-1 and Prymnesin-2:  Potent Hemolytic and Ichthyotoxic Glycosides Isolated from the Red Tide Alga Prymnesium parvum
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Structures and Partial Stereochemical Assignments for Prymnesin-1 and Prymnesin-2:  Potent Hemolytic and Ichthyotoxic Glycosides Isolated from the Red Tide Alga Prymnesium parvum

Igarashi, Tomoji ; Satake, Masayuki ; Yasumoto, Takeshi

Journal of the American Chemical Society, 09/1999, Vol.121(37), pp.8499-8511 [Peer Reviewed Journal]

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19
Prymnesin-2:  A Potent Ichthyotoxic and Hemolytic Glycoside Isolated from the Red Tide Alga Prymnesium parvum
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Prymnesin-2:  A Potent Ichthyotoxic and Hemolytic Glycoside Isolated from the Red Tide Alga Prymnesium parvum

Igarashi, Tomoji ; Satake, Masayuki ; Yasumoto, Takeshi

Journal of the American Chemical Society, 01/1996, Vol.118(2), pp.479-480 [Peer Reviewed Journal]

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20
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Prorocentrolide-A from Cultured Prorocentrum lima Dinoflagellates Collected in Japan Blocks Sub-Types of Nicotinic Acetylcholine Receptors

Amar, Muriel ; Aráoz, Rómulo ; Iorga, Bogdan I ; Yasumoto, Takeshi ; Servent, Denis ; Molgó, Jordi

Toxins, 28 February 2018, Vol.10(3) [Peer Reviewed Journal]

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21
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Determination of toxins involved in ciguatera fish poisoning in the Pacific by LC/MS

Yogi, Kentaro ; Sakugawa, Satsuki ; Oshiro, Naomasa ; Ikehara, Tsuyoshi ; Sugiyama, Kiminori ; Yasumoto, Takeshi

Journal of AOAC International, 2014, Vol.97(2), pp.398-402 [Peer Reviewed Journal]

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22
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Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

Kudo, Yuta ; Yasumoto, Takeshi ; Konoki, Keiichi ; Cho, Yuko ; Yotsu-Yamashita, Mari

Marine Drugs, 2012, Vol.10(3), pp.655-667 [Peer Reviewed Journal]

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23
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The binding of okadaic acid analogs to recombinant OABP2.1 originally isolated from the marine sponge Halichondria okadai

Konoki, Keiichi ; Onoda, Tatsuya ; Furumochi, Sachie ; Cho, Yuko ; Yotsu-Yamashita, Mari ; Yasumoto, Takeshi

Bioorganic & Medicinal Chemistry Letters, 01 November 2013, Vol.23(21), pp.5833-5835 [Peer Reviewed Journal]

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24
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Efficient production of recombinant PP2A at a low temperature using a baculovirus expression system

Ikehara, Tsuyoshi ; Nakashima, Shihoko ; Nakashima, Junichi ; Kinoshita, Tsubasa ; Yasumoto, Takeshi

Biotechnology Reports, September 2016, Vol.11, pp.86-89 [Peer Reviewed Journal]

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25
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Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas

Yamamoto, Kei ; Ishikawa, Chie ; Katano, Harukata ; Yasumoto, Takeshi ; Mori, Naoki

Cancer letters, 28 January 2011, Vol.300(2), pp.225-34 [Peer Reviewed Journal]

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26
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PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish

Ikehara, Tsuyoshi ; Imamura, Shihoko ; Yoshino, Atsushi ; Yasumoto, Takeshi

Toxins, 2010, Vol.2(1), pp.195-204 [Peer Reviewed Journal]

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27
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5,6,11-trideoxytetrodotoxin from the puffer fish, fugu poecilonotus

Yotsu-Yamashita, Mari ; Yamagishi, Yuki ; Yasumoto, Takeshi

Tetrahedron Letters, 1995, Vol.36(51), pp.9329-9332 [Peer Reviewed Journal]

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28
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The absolute configuration of gambierol, a toxic marine polyether from the dinoflagellate, Gambierdiscus toxicus

Morohashi, Akio ; Satake, Masayuki ; Yasumoto, Takeshi

Tetrahedron Letters, 1999, Vol.40(1), pp.97-100 [Peer Reviewed Journal]

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29
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Three challenges toward the assignment of absolute configuration of gymnocin-B

Tanaka, Katsunori ; Itagaki, Yasuhiro ; Satake, Masayuki ; Naoki, Hideo ; Yasumoto, Takeshi ; Nakanishi, Koji ; Berova, Nina

Journal of the American Chemical Society, 06 July 2005, Vol.127(26), pp.9561-70 [Peer Reviewed Journal]

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30
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Liquid chromatography–electrospray ionization mass spectrometry of the diarrhetic shellfish-poisoning toxins okadaic acid, dinophysistoxin-1 and pectenotoxin-6 in bivalves

Suzuki, Toshiyuki ; Yasumoto, Takeshi

Journal of Chromatography A, 2000, Vol.874(2), pp.199-206 [Peer Reviewed Journal]

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31
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Advanced studies for the application of high-performance capillary electrophoresis for the analysis of yessotoxin and 45-hydroxyyessotoxin

de La Iglesia, Pablo ; Gago-Martinez, Ana ; Yasumoto, Takeshi

Journal of Chromatography A, 2007, Vol.1156(1), pp.160-166 [Peer Reviewed Journal]

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32
Total Synthesis and Absolute Configuration of Polycavernoside A
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Total Synthesis and Absolute Configuration of Polycavernoside A

Fujiwara, Kenshu ; Murai, Akio ; Yotsu-Yamashita, Mari ; Yasumoto, Takeshi

Journal of the American Chemical Society, 10/1998, Vol.120(41), pp.10770-10771 [Peer Reviewed Journal]

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33
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Cyclic Guanidine Compounds from Toxic Newts Support the Hypothesis that Tetrodotoxin is Derived from a Monoterpene

Kudo, Yuta ; Yasumoto, Takeshi ; Mebs, Dietrich ; Cho, Yuko ; Konoki, Keiichi ; Yotsu‐Yamashita, Mari

Angewandte Chemie, 18 July 2016, Vol.128(30), pp.8870-8873 [Peer Reviewed Journal]

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34
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Anticancer effects of marine carotenoids, fucoxanthin and its deacetylated product, fucoxanthinol, on osteosarcoma

Rokkaku, Takayoshi ; Kimura, Ryuichiro ; Ishikawa, Chie ; Yasumoto, Takeshi ; Senba, Masachika ; Kanaya, Fuminori ; Mori, Naoki

International Journal of Oncology, 2013, Vol.43(4), pp.1176-1186 [Peer Reviewed Journal]

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35
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The cyclic imine Prorocentrolide-A obtained from cultured Japanese Prorocentrum lima dinoflagellates target muscle- and neuronal-type nicotinic acetylcholine receptors

Amar, Muriel ; Aráoz, Romulo ; Iorga, Bogdan I ; Yasumoto, Takeshi ; Servent, Denis ; Molgó, Jordi

Toxicon, July 2018, Vol.149, pp.103-104 [Peer Reviewed Journal]

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36