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No Exit

Xie, Jenny

Yale Review, April 2020, Vol.108(1), pp.31-31 [Peer Reviewed Journal]

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Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses

Peng, Min ; Xie, Jenny ; Ucher, Anna ; Stavnezer, Janet ; Cantor, Sharon B.

EMBO journal: European Molecular Biology Organization, 2014, Issue 15, pp.1698-1712 [Peer Reviewed Journal]

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Crosstalk between BRCA ‐ F anconi anemia and mismatch repair pathways prevents MSH 2‐dependent aberrant DNA damage responses

Peng, Min ; Xie, Jenny ; Ucher, Anna ; Stavnezer, Janet ; Cantor, Sharon B

EMBO Journal, 01 August 2014, Vol.33(15), pp.1698-1712 [Peer Reviewed Journal]

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RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway

Xie, Jenny ; Kim, Hyungjin ; Moreau, Lisa A ; Puhalla, Shannon ; Garber, Judy ; Al Abo, Muthana ; Takeda, Shunichi ; D'Andrea, Alan D

The Journal of clinical investigation, April 2015, Vol.125(4), pp.1523-32 [Peer Reviewed Journal]

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5
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Long Nights

Xie, Jenny

Literary Review, Summer 2015, Vol.58(3), pp.153-154,158 [Peer Reviewed Journal]

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6
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Article
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Metamorphosis

Xie, Jenny

Poetry, Nov 2017, Vol.211(2), p.122,196 [Peer Reviewed Journal]

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7
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Article
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Ledger

Xie, Jenny

Poetry, May 2018, Vol.212(2), pp.116-117,182 [Peer Reviewed Journal]

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8
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Article
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Something for Everything

Xie, Jenny

Indiana Review, Winter 2012, Vol.34(2), p.168,188 [Peer Reviewed Journal]

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9
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Article
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Lunar New Year, 1988

Xie, Jenny

Harvard Review, 2016, Issue 49, pp.38-40,229 [Peer Reviewed Journal]

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10
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Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders

Liu, Qingjie ; Shi, Qing ; Marcoux, David ; Batt, Douglas G ; Cornelius, Lyndon ; Qin, Lan-Ying ; Ruan, Zheming ; Neels, James ; Beaudoin-Bertrand, Myra ; Srivastava, Anurag S ; Li, Ling ; Cherney, Robert J ; Gong, Hua ; Watterson, Scott H ; Weigelt, Carolyn ; Gillooly, Kathleen M ; Mcintyre, Kim W ; Xie, Jenny H ; Obermeier, Mary T ; Fura, Aberra ; Sleczka, Bogdan ; Stefanski, Kevin ; Fancher, R. M ; Padmanabhan, Shweta ; Rp, Thatipamula ; Kundu, Ipsit ; Rajareddy, Kallem ; Smith, Rodney ; Hennan, James K ; Xing, Dezhi ; Fan, Jingsong ; Levesque, Paul C ; Ruan, Qian ; Pitt, Sidney ; Zhang, Rosemary ; Pedicord, Donna ; Pan, Jie ; Yarde, Melissa ; Lu, Hao ; Lippy, Jonathan ; Goldstine, Christine ; Skala, Stacey ; Rampulla, Richard A ; Mathur, Arvind ; Gupta, Anuradha ; Arunachalam, Pirama Nayagam ; Sack, John S ; Muckelbauer, Jodi K ; Cvijic, Mary Ellen ; Salter-Cid, Luisa M ; Bhide, Rajeev S ; Poss, Michael A ; Hynes, John ; Carter, Percy H ; Macor, John E ; Ruepp, Stefan ; Schieven, Gary L ; Tino, Joseph A Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Medicinal Chemistry, 05 June 2017, Vol.60(12) [Peer Reviewed Journal]

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11
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Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P Receptor Modulator

Yang, Michael G ; Xiao, Zili ; Dhar, T G Murali ; Xiao, Hai-Yun ; Gilmore, John L ; Marcoux, David ; Xie, Jenny H ; Mcintyre, Kim W ; Taylor, Tracy L ; Borowski, Virna ; Heimrich, Elizabeth ; Li, Yu-Wen ; Feng, Jianlin ; Fernandes, Alda ; Yang, Zheng ; Balimane, Praveen ; Marino, Anthony M ; Cornelius, Georgia ; Warrack, Bethanne M ; Mathur

Journal of medicinal chemistry, 22 December 2016, Vol.59(24), pp.11138-11147 [Peer Reviewed Journal]

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12
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FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response (FANCJ Acetylation Promotes the DNA Damage Response)

Xie, Jenny ; Peng, Min ; Guillemette, Shawna ; Quan, Steven ; Maniatis, Stephanie ; Wu, Yuliang ; Venkatesh, Aditya ; Shaffer, Scott A ; Brosh, Robert M ; Cantor, Sharon B Plon, Sharon E. (Editor)

PLoS Genetics, 2012, Vol.8(7), p.e1002786 [Peer Reviewed Journal]

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13
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A stochastic cellular automaton simulation of chemical oscillations in small systems

Hu, Yue ; Xie, Jenny

AIP Advances, December 2018, Vol.8(12) [Peer Reviewed Journal]

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14
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An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy

Xie, Jenny ; Guillemette, Shawna ; Peng, Min ; Gilbert, Candace ; Buermeyer, Andrew ; Cantor, Sharon B

Cancer prevention research (Philadelphia, Pa.), November 2010, Vol.3(11), pp.1409-16 [Peer Reviewed Journal]

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15
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In Search of

Xie, Jenny

Yale Review, April 2020, Vol.108(1), pp.30-30 [Peer Reviewed Journal]

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16
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Conference Proceeding
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Miniradar: A Low Power IEEE 802.15.4 Transceiver Based Implementaion of Bistatic Rader

Ghosh, Pradipth ; Xie, Jenny ; Krishnamachari, Bhaskar

2018 Information Theory and Applications Workshop (ITA), February 2018, pp.1-1

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17
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Article
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Human iPSC Cardiomyocytes Recapitulate Bradycardia Observed in Patients Treated with Sphingosine-1-phosphate Receptor Agonists

Shi, Hong ; Huang, Minxue ; Kwagh, Jae ; Wang, Faye ; Lewen, Geoff ; Xie, Jenny ; Dyckman, Alaric ; Lehman-Mckeeman, Lois ; Levesque, Paul

Journal of Pharmacological and Toxicological Methods, November 2017, Vol.88, pp.242-243 [Peer Reviewed Journal]

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18
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TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat

Zipris, Danny ; Lien, Egil ; Nair, Anjali ; Xie, Jenny X ; Greiner, Dale L ; Mordes, John P ; Rossini, Aldo A

Journal of immunology (Baltimore, Md. : 1950), 15 January 2007, Vol.178(2), pp.693-701 [Peer Reviewed Journal]

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19
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Article
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TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats

Zipris, Danny ; Lien, Egil ; Xie, Jenny X ; Greiner, Dale L ; Mordes, John P ; Rossini, Aldo A

Journal of immunology (Baltimore, Md. : 1950), 01 January 2005, Vol.174(1), pp.131-42 [Peer Reviewed Journal]

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20
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Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells

Xie, Jenny H ; Nomura, Naomi ; Koprak, Sam L ; Quackenbush, Elizabeth J ; Forrest, Michael J ; Rosen, Hugh

Journal of immunology (Baltimore, Md. : 1950), 01 April 2003, Vol.170(7), pp.3662-70 [Peer Reviewed Journal]

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21
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Article
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Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists

Zhu, Yingjie ; Watson, John ; Chen, Mengjie ; Shen, Ding Ren ; Yarde, Melissa ; Agler, Michele ; Burford, Neil ; Alt, Andrew ; Jayachandra, Sukhanya ; Cvijic, Mary Ellen ; Zhang, Litao ; Dyckman, Alaric ; Xie, Jenny ; O’connell, Jonathan ; Banks, Martyn ; Weston, Andrea

Journal of Biomolecular Screening, August 2014, Vol.19(7), pp.1079-1089 [Peer Reviewed Journal]

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22
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Article
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The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells

Peng, Min ; Litman, Rachel ; Xie, Jenny ; Sharma, Sudha ; Brosh, Robert M ; Cantor, Sharon B

The EMBO journal, 11 July 2007, Vol.26(13), pp.3238-49 [Peer Reviewed Journal]

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23
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Article
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The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells

Peng, Min ; Litman, Rachel ; Xie, Jenny ; Sharma, Sudha ; Brosh, Robert M ; Cantor, Sharon B

EMBO Journal, 11 July 2007, Vol.26(13), pp.3238-3249 [Peer Reviewed Journal]

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24
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Conference Proceeding
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Comprehensive Predictions of Tourists' Next Visit Location Based on Call Detail Records Using Machine Learning and Deep Learning Methods

Chen, Nai Chun ; Xie, Wanqin ; Welsch, Roy E ; Larson, Kent ; Xie, Jenny

2017 IEEE International Congress on Big Data (BigData Congress), June 2017, pp.1-6

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25
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Article
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Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations

Zipris, Danny ; Hillebrands, Jan-Luuk ; Welsh, Raymond M ; Rozing, Jan ; Xie, Jenny X ; Mordes, John P ; Greiner, Dale L ; Rossini, Aldo A

Journal of immunology (Baltimore, Md. : 1950), 01 April 2003, Vol.170(7), pp.3592-602 [Peer Reviewed Journal]

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26
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Article
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Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699

Yang, Zheng ; Wang, Haiqing ; Salcedo, Theodora W ; Suchard, Suzanne J ; Xie, Jenny H ; Schneeweis, Lumelle A ; Fleener, Catherine A ; Calore, James D ; Shi, Rong ; Zhang, Sean X Y ; Rodrigues, A David ; Car, Bruce D ; Marathe, Punit H ; Nadler, Steven G

The Journal of pharmacology and experimental therapeutics, December 2015, Vol.355(3), pp.506-15 [Peer Reviewed Journal]

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27
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Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity

Gong, Hua ; Weinstein, David S ; Lu, Zhonghui ; Duan, James J.-W ; Stachura, Sylwia ; Haque, Lauren ; Karmakar, Ananta ; Hemagiri, Hemalatha ; Raut, Dhanya Kumar ; Gupta, Arun Kumar ; Khan, Javed ; Camac, Dan ; Sack, John S ; Pudzianowski, Andrew ; Wu, Dauh-Rurng ; Yarde, Melissa ; Shen, Ding-Ren ; Borowski, Virna ; Xie, Jenny H ; Sun, Huadong

Bioorganic & Medicinal Chemistry Letters, 15 January 2018, Vol.28(2), pp.85-93 [Peer Reviewed Journal]

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28
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Discovery and SAR of pyrrolo[2,1-f][1,2,4]triazin-4-amines as potent and selective PI3Kδ inhibitors

Bhide, Rajeev S ; Neels, James ; Qin, Lan-Ying ; Ruan, Zheming ; Stachura, Sylwia ; Weigelt, Carolyn ; Sack, John S ; Stefanski, Kevin ; Gu, Xiaomei ; Xie, Jenny H ; Goldstine, Christine B ; Skala, Stacey ; Pedicord, Donna L ; Ruepp, Stefan ; Dhar, T.G. Murali ; Carter, Percy H ; Salter-Cid, Luisa M ; Poss, Michael A ; Davies, Paul

Bioorganic & Medicinal Chemistry Letters, 01 September 2016, Vol.26(17), pp.4256-4260 [Peer Reviewed Journal]

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29
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Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors

Qin, Lan-Ying ; Ruan, Zheming ; Cherney, Robert J ; Dhar, T.G. Murali ; Neels, James ; Weigelt, Carolyn A ; Sack, John S ; Srivastava, Anurag S ; Cornelius, Lyndon A.M ; Tino, Joseph A ; Stefanski, Kevin ; Gu, Xiaomei ; Xie, Jenny ; Susulic, Vojkan ; Yang, Xiaoxia ; Yarde-Chinn, Melissa ; Skala, Stacey ; Bosnius, Ruth ; Goldstein, Christine ; Davies, Paul

Bioorganic & Medicinal Chemistry Letters, 15 February 2017, Vol.27(4), pp.855-861 [Peer Reviewed Journal]

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30
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PS3-21 Preclinical validation of CCR5 pharmacodynamic biomarkers

Hung, Chen-Yi ; Gillooly, Kathleen ; Miller, Jesse ; Vuppugalla, Ragini ; Pang, Jian ; Susulic, Vojkan ; Vincelli, Nicole ; Beyer, Sophie ; Xie, Jenny ; Mcintyre, Kim ; West, Wanda ; Carter, Percy ; Davies, Paul ; Salter-Cid, Luisa ; Zhao, Qihong

Cytokine, October 2010, Vol.52(1-2), pp.86-86 [Peer Reviewed Journal]

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31
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Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity

Mangan, Paul R ; Su, Linhui Julie ; Jenny, Victoria ; Tatum, Andrea L ; Picarillo, Caryn ; Skala, Stacey ; Ditto, Noah ; Lin, Zheng ; Yang, Xiaoxia ; Cotter, Pete Z ; Shuster, David J ; Song, Yunling ; Borowski, Virna ; Thomas, Rochelle L ; Heimrich, Elizabeth M ; Devaux, Brigitte ; Das Gupta, Ruchira ; Carvajal, Irvith ; Mcintyre, Kim W ; Xie

The Journal of pharmacology and experimental therapeutics, August 2015, Vol.354(2), pp.152-65 [Peer Reviewed Journal]

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32
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Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases

Xie, Jenny H ; Yamniuk, Aaron P ; Borowski, Virna ; Kuhn, Robert ; Susulic, Vojkan ; Rex-Rabe, Sandra ; Yang, Xiaoxia ; Zhou, Xiadi ; Zhang, Yifan ; Gillooly, Kathleen ; Brosius, Ruth ; Ravishankar, Rathna ; Waggie, Kimberly ; Mink, Kathy ; Price, Laura ; Rehfuss, Robert ; Tamura, James ; An, Yongmi ; Cheng, Lin ; Abramczyk

Journal of immunology (Baltimore, Md. : 1950), 01 May 2014, Vol.192(9), pp.4083-92 [Peer Reviewed Journal]

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33
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Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical Trials

Dhar, T G Murali ; Xiao, Hai-Yun ; Xie, Jenny ; Lehman-Mckeeman, Lois D ; Wu, Dauh-Rurng ; Dabros, Marta ; Yang, Xiaoxia ; Taylor, Tracy L ; Zhou, Xia D ; Heimrich, Elizabeth M ; Thomas, Rochelle ; Mcintyre, Kim W ; Warrack, Bethanne ; Shi, Hong ; Levesque, Paul C ; Zhu, Jia L ; Hennan, James ; Balimane, Praveen ; Yang, Zheng ; Marino

ACS medicinal chemistry letters, 10 March 2016, Vol.7(3), pp.283-8 [Peer Reviewed Journal]

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34
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Article
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Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1)

Guo, Junqing ; Watterson, Scott H ; Spergel, Steven H ; Kempson, James ; Langevine, Charles M ; Shen, Ding Ren ; Yarde, Melissa ; Cvijic, Mary Ellen ; Banas, Dana ; Liu, Richard ; Suchard, Suzanne J ; Gillooly, Kathleen ; Taylor, Tracy ; Rex-Rabe, Sandra ; Shuster, David J ; Mcintyre, Kim W ; Cornelius, Georgia ; D'Arienzo, Celia ; Marino

Bioorganic & medicinal chemistry letters, 15 May 2016, Vol.26(10), pp.2470-2474 [Peer Reviewed Journal]

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35
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Discovery and Structure-Activity Relationship (SAR) of a Series of Ethanolamine-Based Direct-Acting Agonists of Sphingosine-1-phosphate (S1P1)

Gilmore, John L ; Sheppeck, James E ; Watterson, Scott H ; Haque, Lauren ; Mukhopadhyay, Parag ; Tebben, Andrew J ; Galella, Michael A ; Shen, Ding Ren ; Yarde, Melissa ; Cvijic, Mary Ellen ; Borowski, Virna ; Gillooly, Kathleen ; Taylor, Tracy ; Mcintyre, Kim W ; Warrack, Bethanne ; Levesque, Paul C ; Li, Julia P ; Cornelius, Georgia ; D'Arienzo

Journal of medicinal chemistry, 14 July 2016, Vol.59(13), pp.6248-64 [Peer Reviewed Journal]

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36
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Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series

Watterson, Scott H ; Guo, Junqing ; Spergel, Steve H ; Langevine, Charles M ; Moquin, Robert V ; Shen, Ding Ren ; Yarde, Melissa ; Cvijic, Mary Ellen ; Banas, Dana ; Liu, Richard ; Suchard, Suzanne J ; Gillooly, Kathleen ; Taylor, Tracy ; Rex-Rabe, Sandra ; Shuster, David J ; Mcintyre, Kim W ; Cornelius, Georgia ; D'Arienzo, Celia ; Marino

Journal of medicinal chemistry, 24 March 2016, Vol.59(6), pp.2820-40 [Peer Reviewed Journal]

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37
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Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance

Liu, Jinqi ; You, Dan ; Hillerman, Stephen ; Li-Wang, Bifang ; Eraslan, Rukiye ; Xie, Jenny ; Swanson, Jesse ; Ching-Ping, Ho ; Oppenheimer, Simone ; Warrack, Bethanne ; Mcnaney, Colleen ; Nelson, David ; Blum, Jordan ; Kim, Taeg ; Fereshteh, Mark ; Reily, Michael ; Shipkova, Petia ; Sanjuan, Miguel ; Hunt, John ; Salter-Cid

PLoS One, Mar 2019, Vol.14(3), p.e0212670 [Peer Reviewed Journal]

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38
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Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P) Employing Ligand-Based Drug Design

Xiao, Hai-Yun ; Watterson, Scott H ; Langevine, Charles M ; Srivastava, Anurag S ; Ko, Soo S ; Zhang, Yanlei ; Cherney, Robert J ; Guo, Wei-Wei ; Gilmore, John L ; Sheppeck, James E ; Wu, Dauh-Rurng ; Li, Peng ; Ramasamy, Duraisamy ; Arunachalam, Piramanayagam ; Mathur, Arvind ; Taylor, Tracy L ; Shuster, David J ; Mcintyre, Kim W ; Shen, Ding-Ren ; Yarde

Journal of medicinal chemistry, 10 November 2016, Vol.59(21), pp.9837-9854 [Peer Reviewed Journal]

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