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12 Results  for Everything (Includes Articles)

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A new preparation of substituted 4 H ‐1‐benzothiopyran‐4‐ones from c(α) N ‐benzoylhydrazones or c(α) N ‐carboalkoxyhydrazones and methyl thiosalicylate

French, Kristen L. ; Angel, April J. ; Williams, Angela R. ; Hurst, Douglas R. ; Beam, Charles F.

Journal of Heterocyclic Chemistry, January 1998, Vol.35(1), pp.45-48 [Peer Reviewed Journal]

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Structural Optimization Affording 2-( R )-(1-( R )-3,5-Bis(trifluoromethyl)phenylethoxy)-3-( S )-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist
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Structural Optimization Affording 2-( R )-(1-( R )-3,5-Bis(trifluoromethyl)phenylethoxy)-3-( S )-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

Hale, Jeffrey J. ; Mills, Sander G. ; Maccoss, Malcolm ; Finke, Paul E. ; Cascieri, Margaret A. ; Sadowski, Sharon ; Ber, Elzbieta ; Chicchi, Gary G. ; Kurtz, Marc ; Metzger, Joseph ; Eiermann, George ; Tsou, Nancy N. ; Tattersall, F. David ; Rupniak, Nadia M. J. ; Williams, Angela R. ; Rycroft, Wayne ; Hargreaves, Richard ; Macintyre, D. Euan

Journal of Medicinal Chemistry, 11/1998, Vol.41(23), pp.4607-4614 [Peer Reviewed Journal]

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Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs
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Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs

Hale, Jeffrey J. ; Mills, Sander G. ; Maccoss, Malcolm ; Dorn, Conrad P. ; Finke, Paul E. ; Budhu, Richard J. ; Reamer, Robert A. ; Huskey, Su-Er W. ; Luffer-Atlas, Debra ; Dean, Brian J. ; Mcgowan, Erin M. ; Feeney, William P. ; Chiu, Shuet-Hing Lee ; Cascieri, Margaret A. ; Chicchi, Gary G. ; Kurtz, Marc M. ; Sadowski, Sharon ; Ber, Elzbieta ; Tattersall, F. David ; Rupniak, Nadia M. J. ; Williams, Angela R. ; Rycroft, Wayne ; Hargreaves, Richard ; Metzger, Joseph M. ; Macintyre, D. Euan

Journal of Medicinal Chemistry, 03/2000, Vol.43(6), pp.1234-1241 [Peer Reviewed Journal]

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2-Aryl indole NK 1 antagonists: optimisation of the amide substituent

Shaw, Duncan ; Chicchi, Gary G ; Elliott, Jason M ; Kurtz, Marc ; Morrison, Denise ; Ridgill, Mark P ; Szeto, Nicola ; Watt, Alan P ; Williams, Angela R ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(23), pp.3031-3034 [Peer Reviewed Journal]

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2-Aryl indole NK 1 receptor antagonists: optimisation of the 2-Aryl ring and the indole nitrogen substituent

Dinnell, Kevin ; Chicchi, Gary G ; Dhar, Madhumeeta J ; Elliott, Jason M ; Hollingworth, Gregory J ; Kurtz, Marc M ; Ridgill, Mark P ; Rycroft, Wayne ; Tsao, Kwei-Lan ; Williams, Angela R ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(9), pp.1237-1240 [Peer Reviewed Journal]

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2-Aryl Indole NK 1 receptor antagonists: optimisation of indole substitution

Cooper, Laura C ; Chicchi, Gary G ; Dinnell, Kevin ; Elliott, Jason M ; Hollingworth, Gregory J ; Kurtz, Marc M ; Locker, Karen L ; Morrison, Denise ; Shaw, Duncan E ; Tsao, Kwei-Lan ; Watt, Alan P ; Williams, Angela R ; Swain, Christopher J

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(9), pp.1233-1236 [Peer Reviewed Journal]

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Comparison of the functional blockade of rat substance P (NK 1) receptors by GR205171, RP67580, SR140333 and NKP-608

Rupniak, Nadia M.J ; Carlson, Emma J ; Shepheard, Sara ; Bentley, Graham ; Williams, Angela R ; Hill, Alastair ; Swain, Christopher ; Mills, Sander G ; Di Salvo, Jerry ; Kilburn, Ruth ; Cascieri, Margaret A ; Kurtz, Marc M ; Tsao, Kwei-Lan ; Gould, Sandra L ; Chicchi, Gary G

Neuropharmacology, 2003, Vol.45(2), pp.231-241 [Peer Reviewed Journal]

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A New Series of Proton/Charge Transfer Molecules: Synthesis and Spectral Studies of 2‐(5‐Aryl‐1‐carbomethoxy‐1H‐pyrazol‐3‐yl)phenols

Rampey, Mary E. ; Halkyard, Carrie E. ; Williams, Angela R. ; Angel, April J. ; Hurst, Douglas R. ; Townsend, Jessica D. ; Finefrock, Anne E. ; Beam, Charles F. ; Studer‐Martinez, Shannon L.

Photochemistry and Photobiology, August 1999, Vol.70(2), pp.176-183 [Peer Reviewed Journal]

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The preparation of 4,5‐dihydro‐2 H ‐benz[ e ]indazoles from dilithiated 2‐tetralone phenylhydrazone and aromatic esters

Angel, April J. ; Finefrock, Anne E. ; Williams, Angela R. ; Townsend, Jessica D. ; Nguyen, Thuy‐Ha V. ; Hurst, Douglas R. ; Heldrich, Frederick J. ; Beam, Charles F. ; Badejo, Ibraheem T.

Journal of Heterocyclic Chemistry, September 1999, Vol.36(5), pp.1231-1233 [Peer Reviewed Journal]

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The preparation of 4‐oxo‐ N ‐aryl‐4 H ‐1‐benzopyran‐2‐acetamides by the condensation/cyclization of trilithiated acetoacetanilides with lithiated methyl salicylates

Hurst, Douglas R. ; French, Kristen L. ; Angel, April J. ; Williams, Angela R. ; Rampey, Mary E. ; Guion, Tina S. ; Chan, Kam W. ; Kassis, Camille M. ; Martinez, Shannon L. Studer ; Beam, Charles F.

Journal of Heterocyclic Chemistry, November 1998, Vol.35(6), pp.1357-1359 [Peer Reviewed Journal]

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11
The preparation of 4-oxo- N -aryl-4 H -1-benzopyran-2-acetamides by the condensation/cyclization of trilithiated acetoacetanilides with lithiated methyl salicylates
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The preparation of 4-oxo- N -aryl-4 H -1-benzopyran-2-acetamides by the condensation/cyclization of trilithiated acetoacetanilides with lithiated methyl salicylates

Hurst, Douglas R. ; French, Kristen L. ; Angel, April J. ; Williams, Angela R. ; Rampey, Mary E. ; Guion, Tina S. ; Chan, Kam W. ; Kassis, Camille M. ; Martinez, Shannon L. Studer ; Beam, Charles F.

Journal of Heterocyclic Chemistry, 11/1998, Vol.35(6), pp.1357-1359 [Peer Reviewed Journal]

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Cyclopentane-based human NK1 antagonists. Part 2: Development of potent, orally active, water-soluble derivatives

Meurer, Laura C ; Finke, Paul E ; Owens, Karen A ; Tsou, Nancy N ; Ball, Richard G ; Mills, Sander G ; Maccoss, Malcolm ; Sadowski, Sharon ; Cascieri, Margaret A ; Tsao, Kwei-Lan ; Chicchi, Gary G ; Egger, Linda A ; Luell, Silvi ; Metzger, Joseph M ; Macintyre, D. Euan ; Rupniak, Nadia M.J ; Williams, Angela R ; Hargreaves, Richard J

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4504-4511 [Peer Reviewed Journal]

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