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1
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Cobalt-Assisted Claisen Rearrangement of Enediyne Lactones at Ambient Temperature. Studies toward a Synthetic Application of the Myers Cycloaromatization

Vourloumis, Dionisios ; Kim, Kee D ; Petersen, Jeffrey L ; Magriotis, Plato A

The Journal of organic chemistry, 12 July 1996, Vol.61(14), pp.4848-4852 [Peer Reviewed Journal]

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2
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A Homo sapiens cytoplasmic ribosomal decoding A-site affinity screen evaluating aminoglycoside and analogue binding

Kythreoti, Georgia ; Vourloumis, Dionisios

Analytical Biochemistry, 2011, Vol.412(1), pp.102-107 [Peer Reviewed Journal]

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Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins

Nicolaou, K C ; Yin, Jun ; Mandal, Debashis ; Erande, Rohan D ; Klahn, Philipp ; Jin, Michael ; Aujay, Monette ; Sandoval, Joseph ; Gavrilyuk, Julia ; Vourloumis, Dionisios

Journal of the American Chemical Society, 10 February 2016, Vol.138(5), pp.1698-708 [Peer Reviewed Journal]

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4
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Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates

Nicolaou, K C ; Erande, Rohan D ; Yin, Jun ; Vourloumis, Dionisios ; Aujay, Monette ; Sandoval, Joseph ; Munneke, Stefan ; Gavrilyuk, Julia

Journal of the American Chemical Society, 14 March 2018, Vol.140(10), pp.3690-3711 [Peer Reviewed Journal]

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5
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Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids

Androutsopoulos, Vasilis P ; Papakyriakou, Athanasios ; Vourloumis, Dionisios ; Spandidos, Demetrios A

Bioorganic & Medicinal Chemistry, 2011, Vol.19(9), pp.2842-2849 [Peer Reviewed Journal]

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6
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Rigid spiroethers targeting the decoding center of the bacterial ribosome

Mavridis, Ioannis ; Kythreoti, Georgia ; Koltsida, Konstantina ; Vourloumis, Dionisios

Bioorganic & Medicinal Chemistry, 15 February 2014, Vol.22(4), pp.1329-1341 [Peer Reviewed Journal]

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7
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Heterometallic In(III)-Pd(II) Porous Metal-Organic Framework with Square-Octahedron Topology Displaying High CO Uptake and Selectivity toward CH and N

Bratsos, Ioannis ; Tampaxis, Christos ; Spanopoulos, Ioannis ; Demitri, Nicola ; Charalambopoulou, Georgia ; Vourloumis, Dionisios ; Steriotis, Theodore A ; Trikalitis, Pantelis N

Inorganic chemistry, 18 June 2018, Vol.57(12), pp.7244-7251 [Peer Reviewed Journal]

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8
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3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of M1 aminopeptidases with immune-regulating properties

Papakyriakou, Athanasios ; Zervoudi, Efthalia ; Tsoukalidou, Sofia ; Mauvais, Francois-Xavier ; Sfyroera, Georgia ; Mastellos, Dimitrios C ; Van Endert, Peter ; Theodorakis, Emmanuel A ; Vourloumis, Dionisios ; Stratikos, Efstratios

Journal of medicinal chemistry, 12 February 2015, Vol.58(3), pp.1524-43 [Peer Reviewed Journal]

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9
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Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides

Zervoudi, Efthalia ; Papakyriakou, Athanasios ; Georgiadou, Dimitra ; Evnouchidou, Irini ; Gajda, Anna ; Poreba, Marcin ; Salvesen, Guy S ; Drag, Marcin ; Hattori, Akira ; Swevers, Luc ; Vourloumis, Dionisios ; Stratikos, Efstratios Peer, Hal (Editor)

Biochemical Journal, 29 March 2011, Vol.435(2), pp.411-420 [Peer Reviewed Journal]

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Novel selective inhibitors of aminopeptidases that generate antigenic peptides

Papakyriakou, Athanasios ; Zervoudi, Efthalia ; Theodorakis, Emmanuel A ; Saveanu, Loredana ; Stratikos, Efstratios ; Vourloumis, Dionisios

Bioorganic & Medicinal Chemistry Letters, 01 September 2013, Vol.23(17), pp.4832-4836 [Peer Reviewed Journal]

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11
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Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders

Anastasopoulou, Panoula ; Kythreoti, Georgia ; Cosmidis, Tilemachos ; Pyrkotis, Constantina ; Nahmias, Victoria R ; Vourloumis, Dionisios

Bioorganic & Medicinal Chemistry Letters, 15 February 2014, Vol.24(4), pp.1122-1126 [Peer Reviewed Journal]

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12
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Dietary flavonoids in cancer therapy and prevention: Substrates and inhibitors of cytochrome P450 CYP1 enzymes

Androutsopoulos, Vasilis P ; Papakyriakou, Athanasios ; Vourloumis, Dionisios ; Tsatsakis, Aristidis M ; Spandidos, Demetrios A

Pharmacology and Therapeutics, 2010, Vol.126(1), pp.9-20 [Peer Reviewed Journal]

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13
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Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities

Katsarou, Maria E ; Efthimiadou, Eleni K ; Psomas, George ; Karaliota, Alexandra ; Vourloumis, Dionisios

Journal of medicinal chemistry, 14 February 2008, Vol.51(3), pp.470-8 [Peer Reviewed Journal]

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14
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Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation

Nicolaou, K C ; Li, Yiwei ; Sugita, Kazuyuki ; Monenschein, Holger ; Guntupalli, Prasuna ; Mitchell, Helen J ; Fylaktakidou, Konstantina C ; Vourloumis, Dionisios ; Giannakakou, Paraskevi ; O'Brate, Aurora

Journal of the American Chemical Society, 17 December 2003, Vol.125(50), pp.15443-54 [Peer Reviewed Journal]

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15
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Solid-phase synthesis of benzimidazole libraries biased for RNA targets

Vourloumis, Dionisios ; Takahashi, Masayuki ; Simonsen, Klaus B ; Ayida, Benjamin K ; Barluenga, Sofia ; Winters, Geoffrey C ; Hermann, Thomas

Tetrahedron Letters, 2003, Vol.44(14), pp.2807-2811 [Peer Reviewed Journal]

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16
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Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome

Stathakis, Christos I ; Mavridis, Ioannis ; Kythreoti, Georgia ; Papakyriakou, Athanasios ; Katsoulis, Ioannis A ; Cottin, Thomas ; Anastasopoulou, Panoula ; Vourloumis, Dionisios

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(24), pp.7488-7492 [Peer Reviewed Journal]

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17
The Coral-Derived Natural Products Eleutherobin and Sarcodictyins A and B:  Effects on the Assembly of Purified Tubulin with and without Microtubule-Associated Proteins and Binding at the Polymer Taxoid Site
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The Coral-Derived Natural Products Eleutherobin and Sarcodictyins A and B:  Effects on the Assembly of Purified Tubulin with and without Microtubule-Associated Proteins and Binding at the Polymer Taxoid Site

Hamel, Ernest ; Sackett, Dan L. ; Vourloumis, Dionisios ; Nicolaou, K. C.

Biochemistry, 04/1999, Vol.38(17), pp.5490-5498 [Peer Reviewed Journal]

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18
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Novel generation of conjugated alkynyl ketenes: Efficient synthesis of β,γ-alkynyl lactones

Magriotis, Plato A ; Vourloumis, Dionisios ; Scott, Mary E ; Tarli, Anna

Tetrahedron Letters, 1993, Vol.34(13), pp.2071-2074 [Peer Reviewed Journal]

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19
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Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency

Mpakali, Anastasia ; Giastas, Petros ; Deprez-Poulain, Rebecca ; Papakyriakou, Athanasios ; Koumantou, Despoina ; Gealageas, Ronan ; Tsoukalidou, Sofia ; Vourloumis, Dionisios ; Mavridis, Irene M ; Stratikos, Efstratios ; Saridakis, Emmanuel

ACS medicinal chemistry letters, 09 March 2017, Vol.8(3), pp.333-337 [Peer Reviewed Journal]

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20
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Molecular Recognition by Glycoside Pseudo Base Pairs and Triples in an Apramycin–RNA Complex

Han, Qing ; Zhao, Qiang ; Fish, Sarah ; Simonsen, Klaus B. ; Vourloumis, Dionisios ; Froelich, Jamie M. ; Wall, Daniel ; Hermann, Thomas

Angewandte Chemie International Edition, 29 April 2005, Vol.44(18), pp.2694-2700 [Peer Reviewed Journal]

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21
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Monitoring Molecular Recognition of the Ribosomal Decoding Site

Shandrick, Sarah ; Zhao, Qiang ; Han, Qing ; Ayida, Benjamin K. ; Takahashi, Masayuki ; Winters, Geoffrey C. ; Simonsen, Klaus B. ; Vourloumis, Dionisios ; Hermann, Thomas

Angewandte Chemie International Edition, 14 June 2004, Vol.43(24), pp.3177-3182 [Peer Reviewed Journal]

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22
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Total Synthesis of Epothilone E and Analogues with Modified Side Chains through the Stille Coupling Reaction

Nicolaou, K. C. ; He, Yun ; Roschangar, Frank ; King, N. Paul ; Vourloumis, Dionisios ; Li, Tianhu

Angewandte Chemie International Edition, 02 February 1998, Vol.37(1‐2), pp.84-87 [Peer Reviewed Journal]

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23
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Synthesis and Biological Activity of Sarcodictyins

Nicolaou, K. C. ; Kim, Sanghee ; Pfefferkorn, Jeffrey ; Xu, Jinyou ; Ohshima, Takashi ; Hosokawa, Seijiro ; Vourloumis, Dionisios ; Li, Tianhu

Angewandte Chemie International Edition, 05 June 1998, Vol.37(10), pp.1418-1421 [Peer Reviewed Journal]

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24
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Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors

Zhou, Yuefen ; Gregor, Vlad E ; Sun, Zhongxiang ; Ayida, Benjamin K ; Winters, Geoffrey C ; Murphy, Douglas ; Simonsen, Klaus B ; Vourloumis, Dionisios ; Fish, Sarah ; Froelich, Jamie M ; Wall, Daniel ; Hermann, Thomas

Antimicrobial agents and chemotherapy, December 2005, Vol.49(12), pp.4942-9 [Peer Reviewed Journal]

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25
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Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation

Papakyriakou, Athanasios ; Vourloumis, Dionisios ; Tzortzatou‐Stathopoulou, Fotini ; Karpusas, Michael

Proteins: Structure, Function, and Bioinformatics, 01 August 2009, Vol.76(2), pp.375-386 [Peer Reviewed Journal]

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26
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CCDC 1826098: Experimental Crystal Structure Determination

Bratsos, Ioannis ; Tampaxis, Christos ; Spanopoulos, Ioannis ; Demitri, Nicola ; Charalambopoulou, Georgia ; Vourloumis, Dionisios ; Steriotis, Theodore A ; Trikalitis, Pantelis N.

2018

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27
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CCDC 1421073: Experimental Crystal Structure Determination

Nicolaou, Kyriacos C. ; Vourloumis, Dionisios ; Totokotsopoulos, Sotirios ; Papakyriakou, Athanasios ; Karsunky, Holger ; Fernando, Hanan ; Gavrilyuk, Julia ; Webb, Damien ; Stepan, Antonia F.

2015

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28
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CCDC 1826099: Experimental Crystal Structure Determination

Bratsos, Ioannis ; Tampaxis, Christos ; Spanopoulos, Ioannis ; Demitri, Nicola ; Charalambopoulou, Georgia ; Vourloumis, Dionisios ; Steriotis, Theodore A ; Trikalitis, Pantelis N.

2018

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29
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Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics

Ayida, Benjamin K ; Simonsen, Klaus B ; Vourloumis, Dionisios ; Hermann, Thomas

Bioorganic & Medicinal Chemistry Letters, 16 May 2005, Vol.15(10), pp.2457-2460 [Peer Reviewed Journal]

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30
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Chemie und Biologie der Epothilone

Nicolaou, Kyriacos C. ; Roschangar, Frank ; Vourloumis, Dionisios

Angewandte Chemie, 03 August 1998, Vol.110(15), pp.2120-2153 [Peer Reviewed Journal]

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31
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Synthesis and characterization of novel natural product-Gd(III) MRI contrast agent conjugates

Efthimiadou, Eleni K ; Katsarou, Maria E ; Fardis, Michael ; Zikos, Christos ; Pitsinos, Emmanuel N ; Kazantzis, Athanasios ; Leondiadis, Leondios ; Sagnou, Marina ; Vourloumis, Dionisios

Bioorganic & Medicinal Chemistry Letters, 01 December 2008, Vol.18(23), pp.6058-6061 [Peer Reviewed Journal]

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32
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Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts

Nicolaou, K. C. ; Vourloumis, Dionisios ; Winssinger, Nicolas ; Baran, Phil S.

Angewandte Chemie, 03 January 2000, Vol.112(1), pp.46-126 [Peer Reviewed Journal]

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33
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Molecular Recognition by Glycoside Pseudo Base Pairs and Triples in an Apramycin–RNA Complex

Han, Qing ; Zhao, Qiang ; Fish, Sarah ; Simonsen, Klaus B. ; Vourloumis, Dionisios ; Froelich, Jamie M. ; Wall, Daniel ; Hermann, Thomas

Angewandte Chemie, 29 April 2005, Vol.117(18), pp.2754-2760 [Peer Reviewed Journal]

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34
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Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA

Vourloumis, Dionisios ; Takahashi, Masayuki ; Winters, Geoffrey C ; Simonsen, Klaus B ; Ayida, Benjamin K ; Barluenga, Sofia ; Qamar, Seema ; Shandrick, Sarah ; Zhao, Qiang ; Hermann, Thomas

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(23), pp.3367-3372 [Peer Reviewed Journal]

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35
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Monitoring Molecular Recognition of the Ribosomal Decoding Site

Shandrick, Sarah ; Zhao, Qiang ; Han, Qing ; Ayida, Benjamin K. ; Takahashi, Masayuki ; Winters, Geoffrey C. ; Simonsen, Klaus B. ; Vourloumis, Dionisios ; Hermann, Thomas

Angewandte Chemie, 14 June 2004, Vol.116(24), pp.3239-3244 [Peer Reviewed Journal]

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36
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Totalsynthese von Epothilon E und seitenkettenmodifizierten Epothilon‐Analoga durch Stille‐Kupplung

Nicolaou, K.  C. ; He, Yun ; Roschangar, Frank ; King, N.  Paul ; Vourloumis, Dionisios ; Li, Tianhu

Angewandte Chemie, 16 January 1998, Vol.110(1‐2), pp.89-92 [Peer Reviewed Journal]

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37
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Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome

Barluenga, Sofia ; Simonsen, Klaus B ; Littlefield, Ethel S ; Ayida, Benjamin K ; Vourloumis, Dionisios ; Winters, Geoffrey C ; Takahashi, Masayuki ; Shandrick, Sarah ; Zhao, Qiang ; Han, Qing ; Hermann, Thomas

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(3), pp.713-718 [Peer Reviewed Journal]

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38