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Identification of orally available naphthyridine protein kinase D inhibitors

Meredith, Erik L ; Ardayfio, Ophelia ; Beattie, Kimberly ; Dobler, Markus R ; Enyedy, Istvan ; Gaul, Christoph ; Hosagrahara, Vinayak ; Jewell, Charles ; Koch, Keith ; Lee, Wendy ; Lehmann, Hansjoerg ; Mckinsey, Timothy A ; Miranda, Karl ; Pagratis, Nikos ; Pancost, Margaret ; Patnaik, Anup ; Phan, Dillon ; Plato, Craig ; Qian, Ming ; Rajaraman, Vasumathy ; Rao, Chang ; Rozhitskaya, Olga ; Ruppen, Thomas ; Shi, Jie ; Siska, Sarah J ; Springer, Clayton ; Van Eis, Maurice ; Vega, Richard B ; Von Matt, Anette ; Yang, Lihua ; Yoon, Taeyoung ; Zhang, Ji-Hu ; Zhu, Na ; Monovich, Lauren G

Journal of medicinal chemistry, 12 August 2010, Vol.53(15), pp.5400-21 [Peer Reviewed Journal]

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Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties

Hoegenauer, Klemens ; Soldermann, Nicolas ; Hebach, Christina ; Hollingworth, Gregory J ; Lewis, Ian ; Von Matt, Anette ; Smith, Alexander B ; Wolf, Romain M ; Wilcken, Rainer ; Haasen, Dorothea ; Burkhart, Christoph ; Zécri, Frédéric

Bioorganic & Medicinal Chemistry Letters, 01 December 2016, Vol.26(23), pp.5657-5662 [Peer Reviewed Journal]

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New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck

Gommermann, Nina ; Buehlmayer, Peter ; Von Matt, Anette ; Breitenstein, Werner ; Masuya, Keiichi ; Pirard, Bernard ; Furet, Pascal ; Cowan-Jacob, Sandra W ; Weckbecker, Gisbert

Bioorganic & Medicinal Chemistry Letters, 15 June 2010, Vol.20(12), pp.3628-3631 [Peer Reviewed Journal]

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2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes

Van Eis, Maurice J ; Evenou, Jean-Pierre ; Floersheim, Philipp ; Gaul, Christoph ; Cowan-Jacob, Sandra W ; Monovich, Lauren ; Rummel, Gabriele ; Schuler, Walter ; Stark, Wilhelm ; Strauss, Andre ; Von Matt, Anette ; Vangrevelinghe, Eric ; Wagner, Juergen ; Soldermann, Nicolas

Bioorganic & medicinal chemistry letters, 15 December 2011, Vol.21(24), pp.7367-72 [Peer Reviewed Journal]

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Selective boron-Containing thrombin inhibitors—X-ray analysis reveals surprising binding mode

Von Matt, Anette ; Ehrhardt, Claus ; Burkhard, Peter ; Metternich, Rainer ; Walkinshaw, Malcolm ; Tapparelli, Carlo

Bioorganic & Medicinal Chemistry, 2000, Vol.8(9), pp.2291-2303 [Peer Reviewed Journal]

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Aromatic Quinolinecarboxamides as Selective, Orally Active Antibody Production Inhibitors for Prevention of Acute Xenograft Rejection
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Aromatic Quinolinecarboxamides as Selective, Orally Active Antibody Production Inhibitors for Prevention of Acute Xenograft Rejection

Papageorgiou, Christos ; Von Matt, Anette ; Joergensen, Joanne ; Andersen, Elsebeth ; Wagner, Katrin ; Beerli, Christian ; Than, Thai ; Borer, Xaver ; Florineth, Andrea ; Rihs, Gretty ; Schreier, Max H. ; Weckbecker, Gisbert ; Heusser, Christoph

Journal of Medicinal Chemistry, 06/2001, Vol.44(12), pp.1986-1992 [Peer Reviewed Journal]

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