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Ipragliflozin, a sodium–glucose cotransporter 2 inhibitor, reduces bodyweight and fat mass, but not muscle mass, in Japanese type 2 diabetes patients treated with insulin: A randomized clinical trial

Inoue, Hideka ; Morino, Katsutaro ; Ugi, Satoshi ; Tanaka‐Mizuno, Sachiko ; Fuse, Keiko ; Miyazawa, Itsuko ; Kondo, Keiko ; Sato, Daisuke ; Ohashi, Natsuko ; Ida, Shogo ; Sekine, Osamu ; Yoshimura, Masahiro ; Murata, Kiyoshi ; Miura, Katsuyuki ; Arima, Hisatomi ; Maegawa, Hiroshi

Journal of Diabetes Investigation, July 2019, Vol.10(4), pp.1012-1021 [Peer Reviewed Journal]

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Improved glucose metabolism by Eragrostis tef potentially through beige adipocyte formation and attenuating adipose tissue inflammation

Lemecha, Mengistu ; Morino, Katsutaro ; Seifu, Daniel ; Imamura, Takeshi ; Nakagawa, Fumiyuki ; Nagata, Aki ; Okamato, Takuya ; Sekine, Osamu ; Ugi, Satoshi ; Maegawa, Hiroshi

PloS one, 2018, Vol.13(8), pp.e0201661 [Peer Reviewed Journal]

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Pivotal Role of -GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis

Ohashi, Natsuko ; Morino, Katsutaro ; Ida, Shogo ; Sekine, Osamu ; Lemecha, Mengistu ; Kume, Shinji ; Park, Shi-Young ; Choi, Cheol Soo ; Ugi, Satoshi ; Maegawa, Hiroshi

Diabetes, September 2017, Vol.66(9), pp.2351-2362 [Peer Reviewed Journal]

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Predictors for Mild and Severe Hypoglycemia in Insulin-Treated Japanese Diabetic Patients

Sonoda, Nao ; Morimoto, Akiko ; Ugi, Satoshi ; Morino, Katsutaro ; Sekine, Osamu ; Nemoto, Ken-Ichi ; Godai, Kayo ; Maegawa, Hiroshi ; Miyamatsu, Naomi

PLoS One, Jun 2015, Vol.10(6), p.e0130584 [Peer Reviewed Journal]

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Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

Tagawa, Atsuko ; Yasuda, Mako ; Kume, Shinji ; Yamahara, Kosuke ; Nakazawa, Jun ; Chin-Kanasaki, Masami ; Araki, Hisazumi ; Araki, Shin-Ichi ; Koya, Daisuke ; Asanuma, Katsuhiko ; Kim, Eun-Hee ; Haneda, Masakazu ; Kajiwara, Nobuyuki ; Hayashi, Kazuyuki ; Ohashi, Hiroshi ; Ugi, Satoshi ; Maegawa, Hiroshi ; Uzu, Takashi

Diabetes, March 2016, Vol.65(3), pp.755-67 [Peer Reviewed Journal]

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Fiber-rich diet with brown rice improves endothelial function in type 2 diabetes mellitus: A randomized controlled trial

Kondo, Keiko ; Morino, Katsutaro ; Nishio, Yoshihiko ; Ishikado, Atsushi ; Arima, Hisatomi ; Nakao, Keiko ; Nakagawa, Fumiyuki ; Nikami, Fumio ; Sekine, Osamu ; Nemoto, Ken-Ichi ; Suwa, Makoto ; Matsumoto, Motonobu ; Miura, Katsuyuki ; Makino, Taketoshi ; Ugi, Satoshi ; Maegawa, Hiroshi

PLoS One, Jun 2017, Vol.12(6), p.e0179869 [Peer Reviewed Journal]

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Enhanced Intestinal Motility during Oral Glucose Tolerance Test after Laparoscopic Sleeve Gastrectomy: Preliminary Results Using Cine Magnetic Resonance Imaging

Vo, Nguyen ; Yamamoto, Hiroshi ; Furukawa, Akira ; Yamaguchi, Tsuyoshi ; Murata, Satoshi ; Yoshimura, Masahiro ; Murakami, Yoko ; Sato, Shigetaka ; Otani, Hideji ; Ugi, Satoshi ; Morino, Katsutaro ; Maegawa, Hiroshi ; Tani, Tohru

PLoS One, Jun 2013, Vol.8(6), p.e65739 [Peer Reviewed Journal]

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Predictive Properties of Plasma Amino Acid Profile for Cardiovascular Disease in Patients with Type 2 Diabetes

Kume, Shinji ; Araki, Shin-Ichi ; Ono, Nobukazu ; Shinhara, Atsuko ; Muramatsu, Takahiko ; Araki, Hisazumi ; Isshiki, Keiji ; Nakamura, Kazuki ; Miyano, Hiroshi ; Koya, Daisuke ; Haneda, Masakazu ; Ugi, Satoshi ; Kawai, Hiromichi ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

PLoS One, Jun 2014, Vol.9(6), p.e101219 [Peer Reviewed Journal]

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4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation

Ishikado, Atsushi ; Morino, Katsutaro ; Nishio, Yoshihiko ; Nakagawa, Fumiyuki ; Mukose, Atsushi ; Sono, Yoko ; Yoshioka, Nagisa ; Kondo, Keiko ; Sekine, Osamu ; Yoshizaki, Takeshi ; Ugi, Satoshi ; Uzu, Takashi ; Kawai, Hiromichi ; Makino, Taketoshi ; Okamura, Tomio ; Yamamoto, Masayuki ; Kashiwagi, Atsunori ; Maegawa, Hiroshi Schunck, Wolf-Hagen (editor)

PLoS ONE, 2013, Vol.8(7) [Peer Reviewed Journal]

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CCDC3 is specifically upregulated in omental adipose tissue in subjects with abdominal obesity

Ugi, Satoshi ; Maeda, Shiro ; Kawamura, Yoshihiro ; Kobayashi, Masa‐Aki ; Imamura, Minako ; Yoshizaki, Takeshi ; Morino, Katsutaro ; Sekine, Osamu ; Yamamoto, Hiroshi ; Tani, Toru ; Rokushima, Masatomo ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Obesity, April 2014, Vol.22(4), pp.1070-1077 [Peer Reviewed Journal]

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Novel subtype of congenital partial lipodystrophy with mandibular hypoplasia, sensorineural deafness and short stature of unknown genetic origin

Sasaki, Haruka ; Ohkubo, Kumiko ; Kobayashi, Kunihisa ; Tajiri, Yuji ; Ugi, Satoshi ; Kashwagi, Atsunori

Journal of Diabetes Investigation, January 2017, Vol.8(1), pp.121-122 [Peer Reviewed Journal]

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Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues

Ugi, Satoshi ; Nishio, Yoshihiko ; Yamamoto, Hiroshi ; Ikeda, Kazuhiro ; Kobayashi, Masaaki ; Tsukada, Shuichi ; Kondo, Motoyuki ; Morino, Katsutaro ; Obata, Toshiyuki ; Yoshizaki, Takeshi ; Uzu, Takashi ; Naitoh, Hiroyuki ; Tani, Toru ; Maeda, Shiro ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Obesity (Silver Spring, Md.), July 2010, Vol.18(7), pp.1277-82 [Peer Reviewed Journal]

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MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3

Yamamoto, Hirotaka ; Morino, Katsutaro ; Nishio, Yoshihiko ; Ugi, Satoshi ; Yoshizaki, Takeshi ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

American Journal of Physiology, Dec 15, 2012, Vol.303(12), p.E1419 [Peer Reviewed Journal]

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14
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Concentrations of Water-Soluble Vitamins in Blood and Urinary Excretion in Patients with Diabetes Mellitus

Iwakawa, Hiromi ; Nakamura, Yasuyuki ; Fukui, Tomiho ; Fukuwatari, Tsutomu ; Ugi, Satoshi ; Maegawa, Hiroshi ; Doi, Yukio ; Shibata, Katsumi

Nutrition and Metabolic Insights, 2016, Vol.9, pp.85-92 [Peer Reviewed Journal]

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15
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Genetic and epigenetic states of the GNAS complex in pseudohypoparathyroidism type Ib using methylation-specific multiplex ligation-dependent probe amplification assay

Yuno, Akiko ; Usui, Takeshi ; Yambe, Yuko ; Higashi, Kiichiro ; Ugi, Satoshi ; Shinoda, Junji ; Mashio, Yasuo ; Shimatsu, Akira

European journal of endocrinology, February 2013, Vol.168(2), pp.169-75 [Peer Reviewed Journal]

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16
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Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury

Tanaka, Yuki ; Kume, Shinji ; Chin-Kanasaki, Masami ; Araki, Hisazumi ; Araki, Shin-Ichi ; Ugi, Satoshi ; Sugaya, Takeshi ; Uzu, Takashi ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 12 February 2016, Vol.470(3), pp.539-545 [Peer Reviewed Journal]

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17
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Impact of obesity on annual medical expenditures and diabetes care in Japanese patients with type 2 diabetes mellitus

Kusunoki‐Tsuji, Chisato ; Araki, Shin‐Ichi ; Kume, Shinji ; Chin‐Kanasaki, Masami ; Osawa, Norihisa ; Morino, Katsutaro ; Sekine, Osamu ; Ugi, Satoshi ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Journal of Diabetes Investigation, July 2018, Vol.9(4), pp.776-781 [Peer Reviewed Journal]

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18
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Concentrations of Water-Soluble Vitamins in Blood and Urinary Excretion in Patients with Diabetes Mellitus

Iwakawa, Hiromi ; Nakamura, Yasuyuki ; Fukui, Tomiho ; Fukuwatari, Tsutomu ; Ugi, Satoshi ; Maegawa, Hiroshi ; Doi, Yukio ; Shibata, Katsumi

Nutrition and Metabolic Insights, January 2016, Vol.9 [Peer Reviewed Journal]

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19
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Concentrations of Water-Soluble Vitamins in Blood and Urinary Excretion in Patients with Diabetes Mellitus

Iwakawa, Hiromi ; Nakamura, Yasuyuki ; Fukui, Tomiho ; Fukuwatari, Tsutomu ; Ugi, Satoshi ; Maegawa, Hiroshi ; Doi, Yukio ; Shibata, Katsumi

Nutrition and metabolic insights, 2016, Vol.9, pp.85-92 [Peer Reviewed Journal]

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20
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MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis in human induced pluripotent stem cells

Iwasaki, Hirotaka ; Imamura, Takeshi ; Morino, Katsutaro ; Shimosato, Takashi ; Tawa, Masashi ; Ugi, Satoshi ; Sakurai, Hidetoshi ; Maegawa, Hiroshi ; Okamura, Tomio

Biochemical and Biophysical Research Communications, 04 December 2015, Vol.468(1-2), pp.208-213 [Peer Reviewed Journal]

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21
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MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes

Lemecha, Mengistu ; Morino, Katsutaro ; Imamura, Takeshi ; Iwasaki, Hirotaka ; Ohashi, Natsuko ; Ida, Shogo ; Sato, Daisuke ; Sekine, Osamu ; Ugi, Satoshi ; Maegawa, Hiroshi

Scientific reports, 10 October 2018, Vol.8(1), pp.15096 [Peer Reviewed Journal]

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22
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Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors

Hupfeld, Christopher J ; Resnik, Jamie L ; Ugi, Satoshi ; Olefsky, Jerrold M

The Journal of biological chemistry, 14 January 2005, Vol.280(2), pp.1016-23 [Peer Reviewed Journal]

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23
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Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes

Ugi, Satoshi ; Sharma, Prem M ; Ricketts, William ; Imamura, Takeshi ; Olefsky, Jerrold M

The Journal of biological chemistry, 24 May 2002, Vol.277(21), pp.18592-7 [Peer Reviewed Journal]

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24
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Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling

Ugi, Satoshi ; Imamura, Takeshi ; Ricketts, William ; Olefsky, Jerrold M

Molecular and cellular biology, April 2002, Vol.22(7), pp.2375-87 [Peer Reviewed Journal]

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25
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Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes

Kusunoki, Chisato ; Yang, Liu ; Yoshizaki, Takeshi ; Nakagawa, Fumiyuki ; Ishikado, Atsushi ; Kondo, Motoyuki ; Morino, Katsutaro ; Sekine, Osamu ; Ugi, Satoshi ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 04 January 2013, Vol.430(1), pp.225-230 [Peer Reviewed Journal]

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26
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Effect of sleeve gastrectomy on body weight, food intake, glucose tolerance, and metabolic hormone level in two different rat models: Goto-Kakizaki and diet-induced obese rat

Trung, Vo Nguyen ; Yamamoto, Hiroshi ; Yamaguchi, Tsuyoshi ; Murata, Satoshi ; Akabori, Hiroya ; Ugi, Satoshi ; Maegawa, Hiroshi ; Tani, Tohru

Journal of Surgical Research, November 2013, Vol.185(1), pp.159-165 [Peer Reviewed Journal]

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27
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Lack of O-GlcNAcylation enhances exercise-dependent glucose utilization potentially through AMP-activated protein kinase activation in skeletal muscle

Murata, Koichiro ; Morino, Katsutaro ; Ida, Shogo ; Ohashi, Natsuko ; Lemecha, Mengistu ; Park, Shi-Young ; Ishikado, Atsushi ; Kume, Shinji ; Choi, Cheol Soo ; Sekine, Osamu ; Ugi, Satoshi ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 08 January 2018, Vol.495(2), pp.2098-2104 [Peer Reviewed Journal]

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28
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N-3 Polyunsaturated Fatty Acids Decrease the Protein Expression of Soluble Epoxide Hydrolase via Oxidative Stress-Induced P38 Kinase in Rat Endothelial Cells

Okada, Takashi ; Morino, Katsutaro ; Nakagawa, Fumiyuki ; Tawa, Masashi ; Kondo, Keiko ; Sekine, Osamu ; Imamura, Takeshi ; Okamura, Tomio ; Ugi, Satoshi ; Maegawa, Hiroshi

Nutrients, 2017, Vol.9(7), p.654 [Peer Reviewed Journal]

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29
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Postprandial activation of protein kinase Cµ regulates the expression of adipocytokines via the transcription factor AP-2β

Kondo, Motoyuki ; Ugi, Satoshi ; Morino, Katsutaro ; Fuke, Tomoya ; Obata, Toshiyuki ; Yoshizaki, Takeshi ; Nishio, Yoshihiko ; Maeda, Shiro ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

International journal of molecular medicine, July 2011, Vol.28(1), pp.95-100 [Peer Reviewed Journal]

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30
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Overexpression of acetyl CoA carboxylase β exacerbates podocyte injury in the kidney of streptozotocin-induced diabetic mice

Tanaka, Yuki ; Kume, Shinji ; Maeda, Shiro ; Osawa, Norihisa ; Takeda, Naoko ; Chin-Kanasaki, Masami ; Isshiki, Keiji ; Ugi, Satoshi ; Oshima, Itsuki ; Uzu, Takashi ; Maegawa, Hiroshi ; Araki, Shin-Ichi

Biochemical and Biophysical Research Communications, 01 January 2018, Vol.495(1), pp.1115-1121 [Peer Reviewed Journal]

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31
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Diverse metabolic effects of O -GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice

Ida, Shogo ; Morino, Katsutaro ; Sekine, Osamu ; Ohashi, Natsuko ; Kume, Shinji ; Chano, Tokuhiro ; Iwasaki, Kanako ; Harada, Norio ; Inagaki, Nobuya ; Ugi, Satoshi ; Maegawa, Hiroshi

Diabetologia, 2017, Vol.60(9), pp.1761-1769 [Peer Reviewed Journal]

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32
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Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure

Yasuda-Yamahara, Mako ; Kume, Shinji ; Yamahara, Kosuke ; Nakazawa, Jun ; Chin-Kanasaki, Masami ; Araki, Hisazumi ; Araki, Shin-Ichi ; Koya, Daisuke ; Haneda, Masakzu ; Ugi, Satoshi ; Maegawa, Hiroshi ; Uzu, Takashi

Biochemical and Biophysical Research Communications, 18 September 2015, Vol.465(2), pp.249-255 [Peer Reviewed Journal]

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33
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Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet

Ushio, Masateru ; Nishio, Yoshihiko ; Sekine, Osamu ; Nagai, Yoshio ; Maeno, Yasuhiro ; Ugi, Satoshi ; Yoshizaki, Takeshi ; Morino, Katsutaro ; Kume, Shinji ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

American journal of physiology. Endocrinology and metabolism, 15 July 2013, Vol.305(2), pp.E293-304 [Peer Reviewed Journal]

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Acute Effect of Metformin on Postprandial Hypertriglyceridemia through Delayed Gastric Emptying

Sato, Daisuke ; Morino, Katsutaro ; Nakagawa, Fumiyuki ; Murata, Koichiro ; Sekine, Osamu ; Beppu, Fumiaki ; Gotoh, Naohiro ; Ugi, Satoshi ; Maegawa, Hiroshi

International journal of molecular sciences, 16 June 2017, Vol.18(6) [Peer Reviewed Journal]

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35
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Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring

Ugi, Satoshi ; Maegawa, Hiroshi ; Morino, Katsutaro ; Nishio, Yoshihiko ; Sato, Toshiyuki ; Okada, Seiki ; Kikkawa, Yasuo ; Watanabe, Toshihiro ; Nakajima, Hiromu ; Kashiwagi, Atsunori

Diabetes & metabolism journal, August 2016, Vol.40(4), pp.326-33 [Peer Reviewed Journal]

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Autophagy regulates inflammation in adipocytes

Yoshizaki, Takeshi ; Kusunoki, Chisato ; Kondo, Motoyuki ; Yasuda, Mako ; Kume, Shinji ; Morino, Katsutaro ; Sekine, Osamu ; Ugi, Satoshi ; Uzu, Takashi ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 06 January 2012, Vol.417(1), pp.352-357 [Peer Reviewed Journal]

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37