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Correction to Discovery of Potent and Selective 8-Fluorotriazolopyridine c-Met Inhibitors

Peterson, Emily A ; Teffera, Yohannes ; Albrecht, Brian K ; Bauer, David ; Bellon, Steven F ; Boezio, Alessandro ; Boezio, Christiane ; Broome, Martin A ; Choquette, Deborah ; Copeland, Katrina W ; Dussault, Isabelle ; Lewis, Richard ; Lin, Min-Hwa Jasmine ; Lohman, Julia ; Liu, Jingzhou ; Potashman, Michele ; Rex, Karen ; Shimanovich, Roman ; Whittington, Douglas A ; Vaida, Karina R ; Harmange, Jean-Christophe

Journal of medicinal chemistry, 14 May 2015, Vol.58(9), pp.4087 [Peer Reviewed Journal]

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Localization and quantification of drugs in animal tissues by use of desorption electrospray ionization mass spectrometry imaging

Vismeh, Ramin ; Waldon, Daniel J ; Teffera, Yohannes ; Zhao, Zhiyang

Analytical chemistry, 19 June 2012, Vol.84(12), pp.5439-45 [Peer Reviewed Journal]

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Ratios of biliary glutathione disulfide (GSSG) to glutathione (GSH): a potential index to screen drug-induced hepatic oxidative stress in rats and mice

Cao, Lei ; Waldon, Daniel ; Teffera, Yohannes ; Roberts, John ; Wells, Mary ; Langley, Meghan ; Zhao, Zhiyang

Analytical and Bioanalytical Chemistry, 2013, Vol.405(8), pp.2635-2642 [Peer Reviewed Journal]

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Ratios of biliary glutathione disulfide (GSSG) to glutathione (GSH): a potential index to screen drug-induced hepatic oxidative stress in rats and mice

Cao, Lei ; Waldon, Daniel ; Teffera, Yohannes ; Roberts, John ; Wells, Mary ; Langley, Meghan ; Zhao, Zhiyang

Analytical and bioanalytical chemistry, March 2013, Vol.405(8), pp.2635-42 [Peer Reviewed Journal]

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Desorption electrospray ionization tissue imaging using heated nebulizing gas and high‐resolution accurate mass spectra

Waldon, Daniel J. ; Zhao, Zhiyang ; Teffera, Yohannes

Rapid Communications in Mass Spectrometry, 30 August 2010, Vol.24(16), pp.2352-2356 [Peer Reviewed Journal]

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6
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Application of on‐line nano‐liquid chromatography/mass spectrometry in metabolite identification studies

Liu, Jingzhou ; Zhao, Zhiyang ; Teffera, Yohannes

Rapid Communications in Mass Spectrometry, 15 February 2012, Vol.26(3), pp.320-326 [Peer Reviewed Journal]

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Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors

Bregman, Howard ; Chakka, Nagasree ; Guzman-Perez, Angel ; Gunaydin, Hakan ; Gu, Yan ; Huang, Xin ; Berry, Virginia ; Liu, Jingzhou ; Teffera, Yohannes ; Huang, Liyue ; Egge, Bryan ; Mullady, Erin L ; Schneider, Steve ; Andrews, Paul S ; Mishra, Ankita ; Newcomb, John ; Serafino, Randy ; Strathdee, Craig A ; Turci, Susan M ; Wilson, Cindy ; Dimauro, Erin F

Journal of medicinal chemistry, 13 June 2013, Vol.56(11), pp.4320-42 [Peer Reviewed Journal]

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8
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Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2,4triazolo4,3-apyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity

Boezio, Alessandro A ; Copeland, Katrina W ; Rex, Karen ; K Albrecht, Brian ; Bauer, David ; Bellon, Steven F ; Boezio, Christiane ; Broome, Martin A ; Choquette, Deborah ; Coxon, Angela ; Dussault, Isabelle ; Hirai, Satoko ; Lewis, Richard ; Lin, Min-Hwa Jasmine ; Lohman, Julia ; Liu, Jingzhou ; Peterson, Emily A ; Potashman, Michele ; Shimanovich, Roman ; Teffera, Yohannes ; Whittington, Douglas A ; Vaida, Karina R ; Harmange, Jean-Christophe

Journal of medicinal chemistry, 24 March 2016, Vol.59(6), pp.2328-42 [Peer Reviewed Journal]

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The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors

Bregman, Howard ; Simard, Jeffrey R ; Andrews, Kristin L ; Ayube, Shawn ; Chen, Hao ; Gunaydin, Hakan ; Guzman-Perez, Angel ; Hu, Jiali ; Huang, Liyue ; Huang, Xin ; Krolikowski, Paul H ; Lehto, Sonya G ; Lewis, Richard T ; Michelsen, Klaus ; Pegman, Pamela ; Plant, Matthew H ; Shaffer, Paul L ; Teffera, Yohannes ; Yi, Shuyan ; Zhang, Maosheng ; Gingras, Jacinthe ; Dimauro, Erin F

Journal of medicinal chemistry, 09 February 2017, Vol.60(3), pp.1105-1125 [Peer Reviewed Journal]

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Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity

Schenkel, Laurie B ; Olivieri, Philip R ; Boezio, Alessandro A ; Deak, Holly L ; Emkey, Renee ; Graceffa, Russell F ; Gunaydin, Hakan ; Guzman-Perez, Angel ; Lee, Josie H ; Teffera, Yohannes ; Wang, Weiya ; Youngblood, Beth D ; Yu, Violeta L ; Zhang, Maosheng ; Gavva, Narender R ; Lehto, Sonya G ; Geuns-Meyer, Stephanie

Journal of medicinal chemistry, 24 March 2016, Vol.59(6), pp.2794-809 [Peer Reviewed Journal]

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Discovery of potent and selective 8-fluorotriazolopyridine c-Met inhibitors

Peterson, Emily A ; Teffera, Yohannes ; Albrecht, Brian K ; Bauer, David ; Bellon, Steven F ; Boezio, Alessandro ; Boezio, Christiane ; Broome, Martin A ; Choquette, Deborah ; Copeland, Katrina W ; Dussault, Isabelle ; Lewis, Richard ; Lin, Min-Hwa Jasmine ; Lohman, Julia ; Liu, Jingzhou ; Potashman, Michele ; Rex, Karen ; Shimanovich, Roman ; Whittington, Douglas A ; Vaida, Karina R ; Harmange, Jean-Christophe

Journal of medicinal chemistry, 12 March 2015, Vol.58(5), pp.2417-30 [Peer Reviewed Journal]

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12
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The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Lewis, Richard T ; Bode, Christiane M ; Choquette, Deborah M ; Potashman, Michele ; Romero, Karina ; Stellwagen, John C ; Teffera, Yohannes ; Moore, Earl ; Whittington, Douglas A ; Chen, Hao ; Epstein, Linda F ; Emkey, Renee ; Andrews, Paul S ; Yu, Violeta L ; Saffran, Douglas C ; Xu, Man ; Drew, Allison ; Merkel, Patricia ; Szilvassy, Steven ; Brake, Rachael L Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Journal of Medicinal Chemistry, 10 July 2012, Vol.55(14) [Peer Reviewed Journal]

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13
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ASSESSMENT OF MARKETING CHALLENGES AND OPPORTUNITIES OF BRANDED AGRICULTURAL PRODUCTS: THE CASE OF NORTH SHOA ZONE

Ajbie, Dereje ; Abi, Matiwos ; Kossa, Abdela ; Teffera, Yohannes

Innovative Issues and Approaches in Social Sciences, Sep 2018, Vol.11(3), p.67

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14
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Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors

Hua, Zihao ; Bregman, Howard ; Buchanan, John L ; Chakka, Nagasree ; Guzman-Perez, Angel ; Gunaydin, Hakan ; Huang, Xin ; Gu, Yan ; Berry, Virginia ; Liu, Jingzhou ; Teffera, Yohannes ; Huang, Liyue ; Egge, Bryan ; Emkey, Renee ; Mullady, Erin L ; Schneider, Steve ; Andrews, Paul S ; Acquaviva, Lisa ; Dovey, Jennifer ; Mishra, Ankita ; Newcomb, John ; Saffran, Douglas ; Serafino, Randy ; Strathdee, Craig A ; Turci, Susan M ; Stanton, Mary ; Wilson, Cindy ; Dimauro, Erin F

Journal of medicinal chemistry, 27 December 2013, Vol.56(24), pp.10003-15 [Peer Reviewed Journal]

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15
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Whole‐body tissue distribution study of drugs in neonate mice using desorption electrospray ionization mass spectrometry imaging

Liu, Jingzhou ; Gingras, Jacinthe ; Ganley, Kenneth P. ; Vismeh, Ramin ; Teffera, Yohannes ; Zhao, Zhiyang

Rapid Communications in Mass Spectrometry, 30 January 2014, Vol.28(2), pp.185-190 [Peer Reviewed Journal]

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16
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Isotopic differences in human growth hormone preparations

Abramson, Fred ; Osborn, Blaire ; Teffera, Yohannes

Analytical Chemistry, Jun 1, 1996, Vol.68(11), p.1971 [Peer Reviewed Journal]

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17
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Continuous-flow isotope ratio mass spectrometry using the chemical reaction interface with either gas or liquid chromatographic introduction

Teffera, Yohannes ; Kusmierz, Josef ; Abramson, Fred

Analytical Chemistry, Jun 1, 1996, Vol.68(11), p.1888 [Peer Reviewed Journal]

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18
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Identification of quinone imine containing glutathione conjugates of diclofenac in rat bile

Waldon, Daniel J ; Teffera, Yohannes ; Colletti, Adria E ; Liu, Jingzhou ; Zurcher, Danielle ; Copeland, Katrina W ; Zhao, Zhiyang

Chemical research in toxicology, 20 December 2010, Vol.23(12), pp.1947-53 [Peer Reviewed Journal]

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19
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Bioactivation of isothiazoles: minimizing the risk of potential toxicity in drug discovery

Teffera, Yohannes ; Choquette, Deborah ; Liu, Jingzhou ; Colletti, Adria E ; Hollis, L Steven ; Lin, Min-Hwa Jasmine ; Zhao, Zhiyang

Chemical research in toxicology, 15 November 2010, Vol.23(11), pp.1743-52 [Peer Reviewed Journal]

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20
Determination of benzo[a]pyrene sulfate conjugates from benzo[a]pyrene-treated cells by continuous-flow fast atom bombardment mass spectrometry
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Determination of benzo[a]pyrene sulfate conjugates from benzo[a]pyrene-treated cells by continuous-flow fast atom bombardment mass spectrometry

Teffera, Yohannes. ; Baird, William M. ; Smith, David L.

Analytical Chemistry, 03/1991, Vol.63(5), pp.453-456 [Peer Reviewed Journal]

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21
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Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

Lehto, Sonya G ; Weyer, Andy D ; Youngblood, Beth D ; Zhang, Maosheng ; Yin, Ruoyuan ; Wang, Weiya ; Teffera, Yohannes ; Cooke, Melanie ; Stucky, Cheryl L ; Schenkel, Laurie ; Geuns-Meyer, Stephanie ; Moyer, Bryan D ; Wild, Kenneth D ; Gavva, Narender R

Molecular pain, 2016, Vol.12 [Peer Reviewed Journal]

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22
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Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

Lehto, Sonya G ; Weyer, Andy D ; Youngblood, Beth D ; Zhang, Maosheng ; Yin, Ruoyuan ; Wang, Weiya ; Teffera, Yohannes ; Cooke, Melanie ; Stucky, Cheryl L ; Schenkel, Laurie ; Geuns-Meyer, Stephanie ; Moyer, Bryan D ; Wild, Kenneth D ; Gavva, Narender R

Molecular Pain, November 2016, Vol.12 [Peer Reviewed Journal]

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23
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Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators

Huang, Xin ; Shaffer, Paul L ; Ayube, Shawn ; Bregman, Howard ; Chen, Hao ; Lehto, Sonya G ; Luther, Jason A ; Matson, David J ; Mcdonough, Stefan I ; Michelsen, Klaus ; Plant, Matthew H ; Schneider, Stephen ; Simard, Jeffrey R ; Teffera, Yohannes ; Yi, Shuyan ; Zhang, Maosheng ; Dimauro, Erin F ; Gingras, Jacinthe Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Nature Structural & Molecular Biology, 19 December 2016, Vol.24(2) [Peer Reviewed Journal]

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24
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Element- and isotope-specific detection for high-performance liquid chromatography using chemical reaction interface mass spectrometry

Mclean, Matt ; Vestal, Marvin L ; Teffera, Yohannes ; Abramson, Fred P

Journal of Chromatography A, 1996, Vol.732(2), pp.189-199 [Peer Reviewed Journal]

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25
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Discovery of novel 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydroisoquinoline-1(2 H)-ones as potent and selective inhibitors of KDR: Synthesis, SAR, and pharmacokinetic properties

Choquette, Deborah ; Teffera, Yohannes ; Polverino, Anthony ; Harmange, Jean-Christophe

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(14), pp.4054-4058 [Peer Reviewed Journal]

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26
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Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Peterson, Emily A ; Boezio, Alessandro A ; Andrews, Paul S ; Boezio, Christiane M ; Bush, Tammy L ; Cheng, Alan C ; Choquette, Deborah ; Coats, James R ; Colletti, Adria E ; Copeland, Katrina W ; Dupont, Michelle ; Graceffa, Russell ; Grubinska, Barbara ; Kim, Joseph L ; Lewis, Richard T ; Liu, Jingzhou ; Mullady, Erin L ; Potashman, Michele H ; Romero, Karina ; Shaffer, Paul L ; Stanton, Mary K ; Stellwagen, John C ; Teffera, Yohannes ; Yi, Shuyan ; Cai, Ti ; La, Daniel S

Bioorganic & Medicinal Chemistry Letters, 01 August 2012, Vol.22(15), pp.4967-4974 [Peer Reviewed Journal]

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27
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Discovery of triazine-benzimidazoles as selective inhibitors of mTOR

Peterson, Emily A ; Andrews, Paul S ; Be, Xuhai ; Boezio, Alessandro A ; Bush, Tammy L ; Cheng, Alan C ; Coats, James R ; Colletti, Adria E ; Copeland, Katrina W ; Dupont, Michelle ; Graceffa, Russell ; Grubinska, Barbara ; Harmange, Jean-Christophe ; Kim, Joseph L ; Mullady, Erin L ; Olivieri, Philip ; Schenkel, Laurie B ; Stanton, Mary K ; Teffera, Yohannes ; Whittington, Douglas A ; Cai, Ti ; La, Daniel S

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(7), pp.2064-2070 [Peer Reviewed Journal]

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28
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Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458)

Liu, Longbin ; Siegmund, Aaron ; Xi, Ning ; Kaplan-Lefko, Paula ; Rex, Karen ; Chen, April ; Lin, Jasmine ; Moriguchi, Jodi ; Berry, Loren ; Huang, Liyue ; Teffera, Yohannes ; Yang, Yajing ; Zhang, Yihong ; Bellon, Steven F ; Lee, Matthew ; Shimanovich, Roman ; Bak, Annette ; Dominguez, Celia ; Norman, Mark H ; Harmange, Jean-Christophe ; Dussault, Isabelle ; Kim, Tae-Seong

Journal of medicinal chemistry, 10 July 2008, Vol.51(13), pp.3688-91 [Peer Reviewed Journal]

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29
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Corrigendum to “Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors” [Bioorg. Med. Chem. Lett. 19 (2009) 6307]

Boezio, Alessandro A ; Berry, Loren ; Albrecht, Brian K ; Bauer, David ; Bellon, Steven F ; Bode, Christiane ; Chen, April ; Choquette, Deborah ; Dussault, Isabelle ; Fang, Mei ; Hirai, Satoko ; Kaplan-Lefko, Paula ; Larrow, Jay F ; Lin, Min-Hwa Jasmine ; Lohman, Julia ; Potashman, Michele H ; Qu, Yusheng ; Rex, Karen ; Santostefano, Michael ; Shah, Kavita ; Shimanovich, Roman ; Springer, Stephanie K ; Teffera, Yohannes ; Yang, Yajing ; Zhang, Yihong ; Harmange, Jean-Christophe

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(2), pp.773-773 [Peer Reviewed Journal]

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30
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Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis

La, Daniel S ; Belzile, Julie ; Bready, James V ; Coxon, Angela ; Demelfi, Thomas ; Doerr, Nicholas ; Estrada, Juan ; Flynn, Julie C ; Flynn, Shaun R ; Graceffa, Russell F ; Harriman, Shawn P ; Larrow, Jay F ; Long, Alexander M ; Martin, Matthew W ; Morrison, Michael J ; Patel, Vinod F ; Roveto, Philip M ; Wang, Ling ; Weiss, Matthew M ; Whittington, Douglas A ; Teffera, Yohannes ; Zhao, Zhiyang ; Polverino, Anthony J ; Harmange, Jean-Christophe

Journal of medicinal chemistry, 27 March 2008, Vol.51(6), pp.1695-705 [Peer Reviewed Journal]

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31
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Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation

Harmange, Jean-Christophe ; Weiss, Matthew M ; Germain, Julie ; Polverino, Anthony J ; Borg, George ; Bready, James ; Chen, Danlin ; Choquette, Deborah ; Coxon, Angela ; Demelfi, Tom ; Dipietro, Lucian ; Doerr, Nicholas ; Estrada, Juan ; Flynn, Julie ; Graceffa, Russell F ; Harriman, Shawn P ; Kaufman, Stephen ; La, Daniel S ; Long, Alexander ; Martin, Matthew W ; Neervannan, Sesha ; Patel, Vinod F ; Potashman, Michele ; Regal, Kelly ; Roveto, Phillip M ; Schrag, Michael L ; Starnes, Charlie ; Tasker, Andrew ; Teffera, Yohannes ; Wang, Ling ; White, Ryan D ; Whittington, Douglas A ; Zanon, Roger

Journal of medicinal chemistry, 27 March 2008, Vol.51(6), pp.1649-67 [Peer Reviewed Journal]

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32
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Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase

Albrecht, Brian K ; Harmange, Jean-Christophe ; Bauer, David ; Berry, Loren ; Bode, Christiane ; Boezio, Alessandro A ; Chen, April ; Choquette, Deborah ; Dussault, Isabelle ; Fridrich, Cary ; Hirai, Satoko ; Hoffman, Doug ; Larrow, Jay F ; Kaplan-Lefko, Paula ; Lin, Jasmine ; Lohman, Julia ; Long, Alexander M ; Moriguchi, Jodi ; O'Connor, Anne ; Potashman, Michele H ; Reese, Monica ; Rex, Karen ; Siegmund, Aaron ; Shah, Kavita ; Shimanovich, Roman ; Springer, Stephanie K ; Teffera, Yohannes ; Yang, Yajing ; Zhang, Yihong ; Bellon, Steven F

Journal of medicinal chemistry, 22 May 2008, Vol.51(10), pp.2879-82 [Peer Reviewed Journal]

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33
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Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors

Weiss, Matthew M ; Harmange, Jean-Christophe ; Polverino, Anthony J ; Bauer, David ; Berry, Loren ; Berry, Virginia ; Borg, George ; Bready, James ; Chen, Danlin ; Choquette, Deborah ; Coxon, Angela ; Demelfi, Tom ; Doerr, Nicholas ; Estrada, Juan ; Flynn, Julie ; Graceffa, Russell F ; Harriman, Shawn P ; Kaufman, Stephen ; La, Daniel S ; Long, Alexander ; Neervannan, Sesha ; Patel, Vinod F ; Potashman, Michele ; Regal, Kelly ; Roveto, Phillip M ; Schrag, Michael L ; Starnes, Charlie ; Tasker, Andrew ; Teffera, Yohannes ; Whittington, Douglas A ; Zanon, Roger

Journal of medicinal chemistry, 27 March 2008, Vol.51(6), pp.1668-80 [Peer Reviewed Journal]

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34
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Chemical reactivity of methoxy 4-o-aryl quinolines: identification of glutathione displacement products in vitro and in vivo

Teffera, Yohannes ; Colletti, Adria E ; Harmange, Jean Christophe ; Hollis, L Steven ; Albrecht, Brian K ; Boezio, Alessandro A ; Liu, Jingzhou ; Zhao, Zhiyang

Chemical research in toxicology, November 2008, Vol.21(11), pp.2216-22 [Peer Reviewed Journal]

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35
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Direct determination of human urinary cortisol metabolites by [formula omitted]

Yergey, Alfred L ; Teffera, Yohannes ; Esteban, Nora V ; Abramson, Fred P

Steroids, 1995, Vol.60(3), pp.295-298 [Peer Reviewed Journal]

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36
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Flow injection with chemical reaction interface-isotope ratio mass spectrometry: an alternative to off-line combustion for detecting low levels of enriched 13 C in mass balance studies

Chen, Pei ; Teffera, Yohannes ; Black, Gavin ; Abramson, Fred

Journal of the American Society for Mass Spectrometry, 1999, Vol.10(2), pp.153-158 [Peer Reviewed Journal]

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