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The AIRE-230Y Polymorphism Affects AIRE Transcriptional Activity: Potential Influence on AIRE Function in the Thymus

Lovewell, T. R. J. ; Mcdonagh, A. J. ; Messenger, A. G. ; Azzouz, M. ; Tazi - Ahnini, R.

The AIRE-230Y Polymorphism Affects AIRE Transcriptional Activity: Potential Influence on AIRE Function in the Thymus. PLoS ONE, 10 (5\). e0127476 [Peer Reviewed Journal]

2015

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Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss

Redler, S. ; Birch, M. P. ; Drichel, D. ; Dobson, K. ; Brockschmidt, F. F. ; TaziAhnini, R. ; Giehl, K. A. ; Kluck, N. ; Kruse, R. ; Lutz, G. ; Wolff, H. ; Becker, T. ; Nöthen, M. M. ; Messenger, A. G. ; Betz, R. C.

British Journal of Dermatology, September 2011, Vol.165(3), pp.703-705 [Peer Reviewed Journal]

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Meta-analysis of autoimmune regulator-regulated genes in human and murine models: a novel human model provides insights on the role of autoimmune regulator in regulating STAT1 and STAT1-regulated genes

Lovewell, T. ; Mcdonagh, A. ; Messenger, A. ; Azzouz, M. ; Tazi - Ahnini, R.

(2018\) Meta-analysis of autoimmune regulator-regulated genes in human and murine models: a novel human model provides insights on the role of autoimmune regulator in regulating STAT1 and STAT1-regulated genes. Frontiers in Immunology, 9. 1380 [Peer Reviewed Journal]

2018

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The oestrogen receptor 2 ( ESR 2 ) gene in female‐pattern hair loss: replication of association with rs10137185 in German patients

Redler, S. ; Birch, P. ; Drichel, D. ; Hofmann, P. ; Dobson, K. ; Böhmer, A. C. ; Becker, J. ; Giehl, K. A. ; TaziAhnini, R. ; Kruse, R. ; Wolff, H. ; Miesel, A. ; Fischer, T. ; Böhm, M. ; Nuwayhid, R. ; Garcia Bartels, N. ; Lutz, G. ; Becker, T. ; Blume‐Peytavi, U. ; Nöthen, M. M. ; Messenger, A. G. ; Betz, R. C.

British Journal of Dermatology, April 2014, Vol.170(4), pp.982-985 [Peer Reviewed Journal]

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Investigation of the male pattern baldness major genetic susceptibility loci AR / EDA2R and 20p11 in female pattern hair loss

Redler, S. ; Brockschmidt, F. F. ; TaziAhnini, R. ; Drichel, D. ; Birch, M. P. ; Dobson, K. ; Giehl, K. A. ; Herms, S. ; Refke, M. ; Kluck, N. ; Kruse, R. ; Lutz, G. ; Wolff, H. ; Böhm, M. ; Becker, T. ; Nöthen, M. M. ; Messenger, A. G. ; Betz, R. C.

British Journal of Dermatology, June 2012, Vol.166(6), pp.1314-1318 [Peer Reviewed Journal]

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First report of SLC39A4 mutation in acrodermatitis enteropathica family from the Middle East

Abu - Duhier, F. ; Lovewell, T. ; Mcdonagh, A. ; Messenger, A. ; Ibrahimi, A. ; Tazi - Ahnini, R.

(2017\) First report of SLC39A4 mutation in acrodermatitis enteropathica family from the Middle East. International Journal of Dermatology, 56 (5\). e97-e100 [Peer Reviewed Journal]

2017

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7
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Corneodesmosin (MHC S) gene in guttate psoriasis

Tazi-Ahnini, R ; Di Giovine, Fs ; Cox, A ; Keohane, SG ; Cork, Mj

The Lancet, 1999, Vol.354(9178), pp.597-597 [Peer Reviewed Journal]

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Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 MKG2D Lymphocytes of Alopecia Areata Patients.

Hamed, F. N. ; Mcdonagh, A. J. G. ; Almaghrabi, S. ; Bakri, Y. ; Messenger, A. G. ; Tazi - Ahnini, R.

(2018\) Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 MKG2D Lymphocytes of Alopecia Areata Patients. International Journal of Environmental Research and Public Health, 15 (12\). 2882 [Peer Reviewed Journal]

2018

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Whole genome sequencing in an acrodermatitis enteropathica family from the Middle East.

Abu - Duhier, F. ; Pooranachandran, V. ; Mcdonagh, A. J. G. ; Messenger, A. G. ; Cooper - Knock, J. ; Bakri, Y. ; Heath, P. R. ; Tazi - Ahnini, R.

(2018\) Whole genome sequencing in an acrodermatitis enteropathica family from the Middle East. Dermatology Research and Practice, 2018. 1284568 [Peer Reviewed Journal]

2018

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10
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The autoimmune regulator gene ( AIRE ) is strongly associated with vitiligo

TaziAhnini, R. ; Mcdonagh, A. J. G. ; Wengraf, D. A. ; Lovewell, T. R. J. ; Vasilopoulos, Y. ; Messenger, A. G. ; Cork, M. J. ; Gawkrodger, D. J.

British Journal of Dermatology, September 2008, Vol.159(3), pp.591-596 [Peer Reviewed Journal]

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Alterations in the desquamation‐related proteolytic cleavage of corneodesmosin and other corneodesmosomal proteins in psoriatic lesional epidermis

Simon, M. ; TaziAhnini, R. ; Jonca, N. ; Caubet, C. ; Cork, M. J. ; Serre, G.

British Journal of Dermatology, July 2008, Vol.159(1), pp.77-85 [Peer Reviewed Journal]

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12
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Nine procaspases are expressed in normal human epidermis, but only caspase‐14 is fully processed

Raymond, A. ‐A. ; Méchin, M. ‐C. ; Nachat, R. ; Toulza, E. ; TaziAhnini, R. ; Serre, G. ; Simon, M.

British Journal of Dermatology, March 2007, Vol.156(3), pp.420-427 [Peer Reviewed Journal]

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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Tsoi, Lc ; Spain, Sl ; Knight, J ; Ellinghaus, E ; Stuart, Pe ; Capon, F ; Ding, J ; Li, Y ; Tejasvi, T ; Gudjonsson, Je ; Kang, Hm ; Allen, Mh ; Mcmanus, R ; Novelli, G ; Samuelsson, L ; Schalkwijk, J ; Ståhle, M ; Burden, Ad ; Smith, Ch ; Cork, Mj ; Estivill, X ; Bowcock, Am ; Krueger, Gg ; Weger, W ; Worthington, J ; Tazi - Ahnini, R ; Nestle, Fo ; Hayday, A ; Hoffmann, P ; Winkelmann, J ; Wijmenga, C ; Langford, C ; Edkins, S ; Andrews, R ; Blackburn, H ; Strange, A ; Band, G ; Pearson, Rd ; Vukcevic, D ; Spencer, Cca ; Deloukas, P ; Mrowietz, U ; Schreiber, S ; Weidinger, S ; Koks, S ; Kingo, K ; Esko, T ; Metspalu, A ; Lim, Hw ; Voorhees, Jj ; Weichenthal, M ; Wichmann, He ; Chandran, V ; Rosen, Cf ; Rahman, P ; Gladman, Dd ; Griffiths, Cem ; Reis, A ; Kere, J ; Nnair, Rp ; Franke, A ; Barker, Jn ; Abecasis, Gr ; Eelder, Jt ; Ttrembath, R ; Duffin, Kc ; Helms, C ; Goldgar, D ; Paschall, J ; Malloy, Mj ; Pullinger, Cr ; Kane, Jp ; Gardner, J ; Perlmutter, A ; Miner, A ; Feng, Bj ; Hiremagalore, R ; Ike, Rw ; Christophers, E ; Henseler, T ; Ruether, A ; Schrodi, Sj ; Prahalad, S ; Guthery, Sl ; Fischer, J ; Liao, W ; Kwok, P ; Menter, A ; Lathrop, Gm ; Wise, C ; Begovich, Ab ; Onoufriadis, A ; Weale, Me ; Hofer, A ; Salmhofer, W ; Wolf, P ; Kainu, K ; Saarialho - Kere, U ; Suomela, S ; Badorf, P ; Hüffmeier, U ; Kurrat, W ; Küster, W ; Lascorz, J ; Mössner, R ; Schürmeier - Horst, F ; Ständer, M ; Traupe, H ; Bergboer, Jgm ; Heijer, Md ; Van De Kerkhof, Pc ; Zeeuwen, Pljm ; Barnes, L ; Campbell, Le ; Cusack, C ; Coleman, C ; Conroy, J ; Ennis, S ; Fitzgerald, O ; Gallagher, P ; Irvine, Ad ; Kirby, B ; Markham, T ; Mclean, Whi ; Mcpartlin, J ; Rogers, Sf ; Ryan, Aw ; Zawirska, A ; Giardina, E ; Lepre, T ; Perricone, C ; Martín - Ezquerra, G ; Pujol, Rm ; Riveira - Munoz, E ; Inerot, A ; Naluai, Å, T ; Mallbris, L ; Wolk, K ; Leman, J ; Barton, A ; Warren, Rb ; Young, Hs ; Ricano - Ponce, I ; Trynka, G ; Pellett, Fj ; Henschel, A ; Aurand, M ; Bebo, B ; Gieger, C ; Illig, T ; Moebus, S ; Jöckel, Kh ; Erbel, R ; Donnelly, P ; Peltonen, L ; Blackwell, Jm ; Bramon, E ; Brown, Ma ; Casas, Jp ; Corvin, A ; Craddock, N ; Duncanson, A ; Jankowski, J ; Markus, Hs ; Mathew, Cg ; Mccarthy, Mi ; Palmer, Cna ; Plomin, R ; Rautanen, A ; Sawcer, Sj ; Samani, N ; Viswanathan, Ac ; Wood, Nw ; Bellenguez, C ; Freeman, C ; Hellenthal, G ; Giannoulatou, E ; Pirinen, M ; Su, Z ; Hunt, Se ; Gwilliam, R ; Bumpstead, Sj ; Dronov, S ; Gillman, M ; Gray, E ; Hammond, N ; Jayakumar, A ; Mccann, Ot ; Liddle, J ; Perez, Ml ; Potter, Sc ; Ravindrarajah, R ; Ricketts, M ; Waller, M ; Weston, P ; Widaa, S ; Whittaker, P ; Neir, Rp ; Barker, Jnwn ; Elder, Jt ; Trembath, Rc

Tsoi, LC; Spain, SL; Knight, J; Ellinghaus, E; Stuart, PE; Capon, F; Ding, J; LI, Y; Tejasvi, T; Gudjonsson, JE; +191 more... (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature genetics, 44 (12). pp. 1341-1348 [Peer Reviewed Journal]

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14
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Identification of six novel polymorphisms in the human corneodesmosin gene

Guerrin, M ; Vincent, C ; Simon, M ; Tazi Ahnini, R ; Fort, M ; Serre, G

Tissue antigens, January 2001, Vol.57(1), pp.32-8 [Peer Reviewed Journal]

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15
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Role of the Autoimmune Regulator ( AIRE ) gene in alopecia areata: Strong association of a potentially functional AIRE polymorphism with alopecia universalis

TaziAhnini, R. ; Cork, M. J. ; Gawkrodger, D. J. ; Birch, M. P. ; Wengraf, D. ; Mcdonagh, A. J. G. ; Messenger, A. G.

Tissue Antigens, December 2002, Vol.60(6), pp.489-495 [Peer Reviewed Journal]

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16
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Identification of novel single nucleotide polymorphisms within the NOTCH4 gene and determination of association with MHC alleles

TaziAhnini, R. ; Timms, J. M. ; Cox, A. ; Wilson, A. G.

European Journal of Immunogenetics, April 2003, Vol.30(2), pp.101-105 [Peer Reviewed Journal]

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17
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Tsoi, L. C. ; Spain, S. L. ; Knight, J. ; Ellinghaus, E. ; Stuart, P. E. ; Capon, F. ; Ding, J. ; Li, Y. ; Tejasvi, T. ; Gudjonsson, J. E. ; Kang, H. M. ; Allen, M. H. ; Mcmanus, R. ; Novelli, G. ; Samuelsson, L. ; Schalkwijk, J. ; Stahle, M. ; Burden, A. D. ; Smith, C. H. ; Cork, M. J. ; Estivill, X. ; Bowcock, A. M. ; Krueger, G. G. ; Weger, W. ; Worthington, J. ; Tazi - Ahnini, R. ; Nestle, F. O. ; Hayday, A. ; Hoffmann, P. ; Winkelmann, J. ; Wijmenga, C. ; Langford, C. ; Edkins, S. ; Andrews, R. ; Blackburn, H. ; Strange, A. ; Band, G. ; Pearson, R. D. ; Vukcevic, D. ; Spencer, C. C. A. ; Deloukas, P. ; Mrowietz, U. ; Schreiber, S. ; Weidinger, S. ; Koks, S. ; Kingo, K. ; Esko, T. ; Metspalu, A. ; Lim, H. W. ; Voorhees, J. J. ; Weichenthal, M. ; Wichmann, H. E. ; Chandran, V. ; Rosen, C. F. ; Rahman, P. ; Gladman, D. D. ; Griffiths, C. E. M. ; Reis, A. ; Kere, J. ; Nair, R. P. ; Franke, A. ; Barker, J. N. W. N. ; Abecasis, G. R. ; Elder, J. T. ; Trembath, R. C. ; Duffin, K. C. ; Helms, C. ; Goldgar, D. ; Li, Y. ; Paschall, J. ; Malloy, M. J. ; Pullinger, C. R. ; Kane, J. P. ; Gardner, J. ; Perlmutter, A. ; Miner, A. ; Feng, B. J. ; Hiremagalore, R. ; Ike, R. W. ; Christophers, E. ; Henseler, T. ; Ruether, A. ; Schrodi, S. J. ; Prahalad, S. ; Guthery, S. L. ; Fischer, J. ; Liao, W. ; Kwok, P. ; Menter, A. ; Lathrop, G. M. ; Wise, C. ; Begovich, A. B. ; Onoufriadis, A. ; Weale, M. E. ; Hofer, A. ; Salmhofer, W. ; Wolf, P. ; Kainu, K. ; Saarialho - Kere, U. ; Suomela, S. ; Badorf, P. ; Hueffmeier, U. ; Kurrat, W. ; Kuester, W. ; Lascorz, J. ; Moessner, R. ; Schuermeier - Horst, F. ; Staender, M. ; Traupe, H. ; Bergboer, J. G. M. ; Den Heijer, M. ; Van De Kerkhof, P. C. ; Zeeuwen, P. L. J. M. ; Barnes, L. ; Campbell, L. E. ; Cusack, C. ; Coleman, C. ; Conroy, J. ; Ennis, S. ; Fitzgerald, O. ; Gallagher, P. ; Irvine, A. D. ; Kirby, B. ; Markham, T. ; Mclean, W. H. I. ; Mcpartlin, J. ; Rogers, S. F. ; Ryan, A. W. ; Zawirska, A. ; Giardina, E. ; Lepre, T. ; Perricone, C. ; Martin - Ezquerra, G. ; Pujol, R. M. ; Riveira - Munoz, E. ; Inerot, A. ; Naluai, A. T. ; Mallbris, L. ; Wolk, K. ; Leman, J. ; Barton, A. ; Warren, R. B. ; Young, H. S. ; Ricano - Ponce, I. ; Trynka, G. ; Pellett, F. J. ; Henschel, A. ; Aurand, M. ; Bebo, B. ; Gieger, C. ; Illig, T. ; Moebus, S. ; Joeckel, K - H. ; Erbe, R. ; Donnelly, P. ; Peltonen, L. ; Blackwell, J. M. ; Bramon, E. ; Brown, M. A. ; Casas, J. P. ; Corvin, A. ; Craddock, N. ; Duncanson, A. ; Jankowski, J. ; Markus, H. S. ; Mathew, C. G. ; Mccarthy, M. I. ; Palmer, C. N. A. ; Plomin, R. ; Rautanen, A. ; Sawcer, S. J. ; Samani, N. ; Viswanathan, A. C. ; Wood, N. W. ; Bellenguez, C. ; Freeman, C. ; Hellenthal, G. ; Giannoulatou, E. ; Pirinen, M. ; Su, Z. ; Hunt, S. E. ; Gwilliam, R. ; Bumpstead, S. J. ; Dronov, S. ; Gillman, M. ; Gray, E. ; Hammond, N. ; Jayakumar, A. ; Mccann, O. T. ; Liddle, J. ; Perez, M. L. ; Potter, S. C. ; Ravindrarajah, R. ; Ricketts, M. ; Waller, M. ; Weston, P. ; Widaa, S. ; Whittaker, P. ; Psoriasi, C. A. S. ; Consortium, G. A. P. ; Extension, P. A. G. ; Consor, W. T. C. C.

(2012\) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature Genetics, 44 (12\). pp. 1341-1348 [Peer Reviewed Journal]

2012

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18
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Original article

Vasilopoulos, Y ; Cork, M ; Teare, D ; Marinou, I ; Ward, S ; Duff, G ; Tazi-Ahnini, R

Allergy, May 2007, Vol.62(5), pp.514-519 [Peer Reviewed Journal]

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19
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Genetic Association Between an AACC Insertion in the 3′UTR of the Stratum Corneum Chymotryptic Enzyme Gene and Atopic Dermatitis

Vasilopoulos, Y ; Cork, M.J ; Murphy, R ; Williams, H.C ; Robinson, D.A ; Duff, G.W ; Ward, S.J ; Tazi-Ahnini, R

Journal of Investigative Dermatology, July 2004, Vol.123(1), pp.62-66 [Peer Reviewed Journal]

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20
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Notch4 , a non-HLA gene in the MHC is strongly associated with the most severe form of alopecia areata

Tazi-Ahnini, R. ; Cork, M. J. ; Wengraf, D. ; Wilson, A. G. ; Gawkrodger, D. J. ; Birch, M. P. ; Messenger, A. G. ; McDonagh, A. J. G.

Human Genetics, 2003, Vol.112(4), pp.400-403 [Peer Reviewed Journal]

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21
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A nonsynonymous substitution of cystatin A, a cysteine protease inhibitor of house dust mite protease, leads to decreased mRNA stability and shows a significant association with atopic dermatitis

Vasilopoulos, Y. ; Cork, M. J. ; Teare, D. ; Marinou, I. ; Ward, S. J. ; Duff, G. W. ; TaziAhnini, R.

Allergy, May 2007, Vol.62(5), pp.514-519 [Peer Reviewed Journal]

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22
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Association analysis of IL1A and IL1B variants in alopecia areata

Tazi-Ahnini, R ; Mcdonagh, A J ; Cox, A ; Messenger, A G ; Britton, J E ; Ward, S J ; Båvik, C O ; Duff, G W ; Cork, M J

Heredity, August 2001, Vol.87(Pt 2), pp.215-9 [Peer Reviewed Journal]

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23
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Genetic analysis of autoimmune regulator haplotypes in alopecia areata

Wengraf, D. A. ; Mcdonagh, A. J. G. ; Lovewell, T. R. J. ; Vasilopoulos, Y. ; Macdonald‐Hull, S. P. ; Cork, M. J. ; Messenger, A. G. ; TaziAhnini, R.

Tissue Antigens, March 2008, Vol.71(3), pp.206-212 [Peer Reviewed Journal]

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24
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A first map of the porcine major histocompatibility complex class I region

Velten, F. ; Rogel‐Gaillard, C. ; Renard, C. ; Chardon, P. ; Pontarotti, P. ; TaziAhnini, R. ; Vaiman, M.

Tissue Antigens, February 1998, Vol.51(2), pp.183-194 [Peer Reviewed Journal]

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25
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Genetic analysis of the interleukin‐1 receptor antagonist and its homologue IL‐1L1 in alopecia areata: strong severity association and possible gene interaction‡

TaziAhnini, R. ; Cox, A. ; Mcdonagh, A. J. G. ; Nicklin, M. J. H. ; Di Giovine, F. S. ; Timms, J. M. ; Messenger, A. G. ; Dimitropoulou, P. ; Duff, G. W. ; Cork, M. J.

European Journal of Immunogenetics, February 2002, Vol.29(1), pp.25-30 [Peer Reviewed Journal]

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26
Geography and History of the Genes in the Human MHC: Can We Predict MHC Organization in Nonhuman Primates?
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Geography and History of the Genes in the Human MHC: Can We Predict MHC Organization in Nonhuman Primates?

Tazi Ahnini, R ; Henry, J ; Pontarotti, Pierre Pontarotti, Pierre (Editor)

1997

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27
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Review
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Epidemiology and genetics of alopecia areata

Mcdonagh, A. J. G. ; TaziAhnini, R.

Clinical and Experimental Dermatology, July 2002, Vol.27(5), pp.405-409 [Peer Reviewed Journal]

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