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1
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PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes

Putz, Eva Maria ; Prchal-Murphy, Michaela ; Simma, Olivia Annabella ; Forster, Florian ; Koenig, Xaver ; Stockinger, Hannes ; Piekorz, Roland P ; Freissmuth, Michael ; Müller, Mathias ; Sexl, Veronika ; Zebedin-Brandl, Eva

PloS one, 2012, Vol.7(7), pp.e40852 [Peer Reviewed Journal]

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Granzyme A activates another way to die

Lieberman, Judy

Immunological reviews, May 2010, Vol.235(1), pp.93-104 [Peer Reviewed Journal]

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Proteasomes in immune cells: more than peptide producers?

Groettrup, Marcus ; Kirk, Christopher J ; Basler, Michael

Nature reviews. Immunology, January 2010, Vol.10(1), pp.73-8 [Peer Reviewed Journal]

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Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A

Zhang, D ; Pasternack, M S ; Beresford, P J ; Wagner, L ; Greenberg, A H ; Lieberman, J

The Journal of biological chemistry, 02 February 2001, Vol.276(5), pp.3683-90 [Peer Reviewed Journal]

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Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions

Revell, Paula A ; Grossman, William J ; Thomas, Dori A ; Cao, Xuefang ; Behl, Rajesh ; Ratner, Jane A ; Lu, Zhi Hong ; Ley, Timothy J

Journal of immunology (Baltimore, Md. : 1950), 15 February 2005, Vol.174(4), pp.2124-31 [Peer Reviewed Journal]

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Determining optimal cytotoxic activity of human Her2neu specific CD8 T cells by comparing the Cr51 release assay to the xCELLigence system

Erskine, Courtney L ; Henle, Andrea M ; Knutson, Keith L

Journal of visualized experiments : JoVE, 08 August 2012(66), pp.e3683 [Peer Reviewed Journal]

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7
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Granulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells

Saini, Reena V ; Wilson, Christine ; Finn, Michael W ; Wang, Tianhong ; Krensky, Alan M ; Clayberger, Carol

Journal of immunology (Baltimore, Md. : 1950), 15 March 2011, Vol.186(6), pp.3497-504 [Peer Reviewed Journal]

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Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes

Trapani, J A ; Klein, J L ; White, P C ; Dupont, B

Proceedings of the National Academy of Sciences of the United States of America, September 1988, Vol.85(18), pp.6924-8 [Peer Reviewed Journal]

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9
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Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes

Jenne, D ; Rey, C ; Haefliger, J A ; Qiao, B Y ; Groscurth, P ; Tschopp, J

Proceedings of the National Academy of Sciences of the United States of America, July 1988, Vol.85(13), pp.4814-8 [Peer Reviewed Journal]

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10
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Serine protease inhibitors and cytotoxic T lymphocytes

Ashton-Rickardt, Philip G

Immunological reviews, May 2010, Vol.235(1), pp.147-58 [Peer Reviewed Journal]

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11
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Functional dissection of the granzyme family: cell death and inflammation

Anthony, Desiree A ; Andrews, Daniel M ; Watt, Sally V ; Trapani, Joseph A ; Smyth, Mark J

Immunological reviews, May 2010, Vol.235(1), pp.73-92 [Peer Reviewed Journal]

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12
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The role of perforin and granzymes in diabetes

Thomas, H E ; Trapani, J A ; Kay, T W H

Cell death and differentiation, April 2010, Vol.17(4), pp.577-85 [Peer Reviewed Journal]

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Orphan granzymes find a home

Bovenschen, Niels ; Kummer, J Alain

Immunological reviews, May 2010, Vol.235(1), pp.117-27 [Peer Reviewed Journal]

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14
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Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B

Afonina, Inna S ; Cullen, Sean P ; Martin, Seamus J

Immunological reviews, May 2010, Vol.235(1), pp.105-16 [Peer Reviewed Journal]

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15
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Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state

Andrade, Felipe

Immunological reviews, May 2010, Vol.235(1), pp.128-46 [Peer Reviewed Journal]

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16
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Control of granzymes by serpins

Kaiserman, D ; Bird, P I

Cell death and differentiation, April 2010, Vol.17(4), pp.586-95 [Peer Reviewed Journal]

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17
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The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes

Edwards, K M ; Kam, C M ; Powers, J C ; Trapani, J A

The Journal of biological chemistry, 22 October 1999, Vol.274(43), pp.30468-73 [Peer Reviewed Journal]

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18
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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B

Darmon, Alison ; Nicholson, Donald ; Bleackley, R

Nature, Oct 5, 1995, Vol.377(6548), pp.446-8 [Peer Reviewed Journal]

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19
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Granzyme B activity in target cells detects attack by cytotoxic lymphocytes

Packard, Beverly Z ; Telford, William G ; Komoriya, Akira ; Henkart, Pierre A

Journal of immunology (Baltimore, Md. : 1950), 15 September 2007, Vol.179(6), pp.3812-20 [Peer Reviewed Journal]

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20
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Deoxyribonuclease induction in apoptotic cytotoxic T lymphocytes

Deng, G ; Podack, E R

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, May 1995, Vol.9(8), pp.665-9 [Peer Reviewed Journal]

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21
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Resistance of tumor cells to cytolytic T lymphocytes involves Rho-GTPases and focal adhesion kinase activation

Abouzahr-Rifai, Soraya ; Hasmim, Meriem ; Boukerche, Habib ; Hamelin, Jocelyne ; Janji, Bassam ; Jalil, Abdelali ; Kieda, Claudine ; Mami-Chouaib, Fathia ; Bertoglio, Jacques ; Chouaib, Salem

The Journal of biological chemistry, 14 November 2008, Vol.283(46), pp.31665-72 [Peer Reviewed Journal]

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22
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T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses

Tarasenko, Tatyana ; Kole, Hemanta K ; Chi, Anthony W ; Mentink-Kane, Margaret M ; Wynn, Thomas A ; Bolland, Silvia

Proceedings of the National Academy of Sciences of the United States of America, 03 July 2007, Vol.104(27), pp.11382-7 [Peer Reviewed Journal]

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23
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Caspase 8 activity in membrane blebs after anti-Fas ligation

Packard, B Z ; Komoriya, A ; Brotz, T M ; Henkart, P A

Journal of immunology (Baltimore, Md. : 1950), 01 November 2001, Vol.167(9), pp.5061-6 [Peer Reviewed Journal]

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24
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Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway

Casciola-Rosen, Livia ; Garcia-Calvo, Margarita ; Bull, Herbert G ; Becker, Joseph W ; Hines, Tonie ; Thornberry, Nancy A ; Rosen, Antony

The Journal of biological chemistry, 16 February 2007, Vol.282(7), pp.4545-52 [Peer Reviewed Journal]

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25
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Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration

Zumwalt, Timothy J ; Arnold, Mildred ; Goel, Ajay ; Boland, C Richard

Oncotarget, 20 February 2015, Vol.6(5), pp.2981-91 [Peer Reviewed Journal]

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26
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Metabolism, migration and memory in cytotoxic T cells

Finlay, David ; Cantrell, Doreen A

Nature reviews. Immunology, February 2011, Vol.11(2), pp.109-17 [Peer Reviewed Journal]

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27
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Centrosome docking at the immunological synapse is controlled by Lck signaling

Tsun, Andy ; Qureshi, Ihjaaz ; Stinchcombe, Jane C ; Jenkins, Misty R ; De La Roche, Maike ; Kleczkowska, Joanna ; Zamoyska, Rose ; Griffiths, Gillian M

The Journal of cell biology, 21 February 2011, Vol.192(4), pp.663-74 [Peer Reviewed Journal]

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28
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Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes

Suidan, H S ; Bouvier, J ; Schaerer, E ; Stone, S R ; Monard, D ; Tschopp, J

Proceedings of the National Academy of Sciences of the United States of America, 16 August 1994, Vol.91(17), pp.8112-6 [Peer Reviewed Journal]

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29
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Perforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritis

Griffiths, G M ; Alpert, S ; Lambert, E ; Mcguire, J ; Weissman, I L

Proceedings of the National Academy of Sciences of the United States of America, 15 January 1992, Vol.89(2), pp.549-53 [Peer Reviewed Journal]

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30
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Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

Grujic, Mirjana ; Braga, Tiago ; Lukinius, Agneta ; Eloranta, Maija-Leena ; Knight, Stefan D ; Pejler, Gunnar ; Abrink, Magnus

The Journal of biological chemistry, 30 September 2005, Vol.280(39), pp.33411-8 [Peer Reviewed Journal]

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31
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How to induce involuntary suicide: the need for dipeptidyl peptidase I

Podack, E R

Proceedings of the National Academy of Sciences of the United States of America, 20 July 1999, Vol.96(15), pp.8312-4 [Peer Reviewed Journal]

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32
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Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein

Pinkoski, M J ; Winkler, U ; Hudig, D ; Bleackley, R C

The Journal of biological chemistry, 26 April 1996, Vol.271(17), pp.10225-9 [Peer Reviewed Journal]

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33
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ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

Duan, H ; Orth, K ; Chinnaiyan, A M ; Poirier, G G ; Froelich, C J ; He, W W ; Dixit, V M

The Journal of biological chemistry, 12 July 1996, Vol.271(28), pp.16720-4 [Peer Reviewed Journal]

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34
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In vivo regulation of murine granzyme B gene transcription in activated primary T cells

Babichuk, C K ; Duggan, B L ; Bleackley, R C

The Journal of biological chemistry, 12 July 1996, Vol.271(28), pp.16485-93 [Peer Reviewed Journal]

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35
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Delivery and therapeutic potential of human granzyme B

Kurschus, Florian C ; Jenne, Dieter E

Immunological reviews, May 2010, Vol.235(1), pp.159-71 [Peer Reviewed Journal]

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36
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The clinicopathological significance of the expression of Granzyme B in oral squamous cell carcinoma

Costa, Nádia Lago ; Alencar, Rita De Cássia Gonçalves ; Valadares, Marize Campos ; Silva, Tarcília Aparecida ; Mendonça, Elismauro Francisco ; Batista, Aline Carvalho

Oral oncology, March 2010, Vol.46(3), pp.185-9 [Peer Reviewed Journal]

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37
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Perforin deficiency and susceptibility to cancer

Brennan, A J ; Chia, J ; Trapani, J A ; Voskoboinik, I

Cell death and differentiation, April 2010, Vol.17(4), pp.607-15 [Peer Reviewed Journal]

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38
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Structure and evolution of the cytotoxic cell proteinase genes CCP3, CCP4 and CCP5

Prendergast, J A ; Pinkoski, M ; Wolfenden, A ; Bleackley, R C

Journal of molecular biology, 20 August 1991, Vol.220(4), pp.867-75 [Peer Reviewed Journal]

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