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33 Results  for Everything (Includes Articles)

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Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents

Elsaman, Tilal ; Mohamed, Malik Suliman ; Mohamed, Magdi A

Bioorganic Chemistry, July 2019, Vol.88 [Peer Reviewed Journal]

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Control of ozonolysis kinetics and aerosol yield by nuances in the molecular structure of volatile organic compounds

Harvey, Rebecca M ; Petrucci, Giuseppe A

Atmospheric Environment, December 2015, Vol.122, pp.188-195 [Peer Reviewed Journal]

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Therapeutic potential of chalcones as cardiovascular agents

Mahapatra, Debarshi Kar ; Bharti, Sanjay Kumar

Life Sciences, 01 March 2016, Vol.148, pp.154-172 [Peer Reviewed Journal]

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European Chemicals Agency dossier submissions as an experimental data source: Refinement of a fish toxicity model for predicting acute LC50 values

Austin, Thomas ; Denoyelle, Marieva ; Chaudry, Amjad ; Stradling, Sam ; Eadsforth, Charles

Environmental Toxicology and Chemistry, February 2015, Vol.34(2), pp.369-378 [Peer Reviewed Journal]

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Synthesis of novel substituted pyrimidine derivatives bearing a sulfamide group and their in vitro cancer growth inhibition activity

Lefebvre, Carole-Anne ; Forcellini, Elsa ; Boutin, Sophie ; Côté, Marie-France ; C.-Gaudreault, René ; Mathieu, Patrick ; Lagüe, Patrick ; Paquin, Jean-François

Bioorganic & Medicinal Chemistry Letters, 15 January 2017, Vol.27(2), pp.299-302 [Peer Reviewed Journal]

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Identification of novel 2-aminothiazole conjugated nitrofuran as antitubercular and antibacterial agents

Ran, Kai ; Gao, Chao ; Deng, Hongxia ; Lei, Qian ; You, Xinyu ; Wang, Ningyu ; Shi, Yaojie ; Liu, Zhihao ; Wei, Wei ; Peng, Cuiting ; Xiong, Lu ; Xiao, Kunjie ; Yu, Luoting

Bioorganic & Medicinal Chemistry Letters, 01 August 2016, Vol.26(15), pp.3669-3674 [Peer Reviewed Journal]

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Decoquinate derivatives: A new class of potent antischistosomal agents against Schistosoma japonicum

Wang, Wen-Long ; Song, Li-Jun ; Hu, Bo-Chun ; Miao, Li ; Chen, Xiao-Yu ; Fan, Wen-Hua ; Yin, Xu-Ren ; Shen, Shuang ; Ding, Zhao-Feng ; Yu, Chuan-Xin

Chinese Chemical Letters, July 2017, Vol.28(7), pp.1547-1552 [Peer Reviewed Journal]

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Synthesis and evaluation of novel thiazole‐based derivatives as selective inhibitors of DNA‐binding domain of the androgen receptor

Xu, Ruixue ; Tian, Ye ; Huang, Shenzhen ; Yu, Jiang ; Deng, Yufang ; Zhan, Miao ; Zhang, Tao ; Wang, Fangying ; Zhao, Lifeng ; Chen, Yuanwei

Chemical Biology & Drug Design, January 2018, Vol.91(1), pp.172-180 [Peer Reviewed Journal]

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Synthesis and cytotoxicity evaluation of 4′-amino-4′-dehydroxyloleandrin derivatives

Chen, Hu ; Lei, Min ; Ma, Biao ; Liu, Miao ; Guo, Dean ; Liu, Xuan ; Hu, Lihong

Fitoterapia, September 2016, Vol.113, pp.85-90 [Peer Reviewed Journal]

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Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives

Xiao, Chengqian ; Tian, Yunan ; Lei, Min ; Chen, Fanglei ; Gan, Xianwen ; Yao, Xingang ; Shen, Xu ; Chen, Jing ; Hu, Lihong

Bioorganic & Medicinal Chemistry Letters, 01 March 2017, Vol.27(5), pp.1316-1318 [Peer Reviewed Journal]

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Synthesis and biological evaluation of N9-substituted harmine derivatives as potential anticancer agents

Du, Hongtao ; Tian, Shan ; Chen, Juncheng ; Gu, Hongling ; Li, Na ; Wang, Junru

Bioorganic & Medicinal Chemistry Letters, 15 August 2016, Vol.26(16), pp.4015-4019 [Peer Reviewed Journal]

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UVCB substances: Methodology for structural description and application to fate and hazard assessment

Dimitrov, Sabcho D. ; Georgieva, Denitsa G. ; Pavlov, Todor S. ; Karakolev, Yordan H. ; Karamertzanis, Panagiotis G. ; Rasenberg, Mike ; Mekenyan, Ovanes G.

Environmental Toxicology and Chemistry, November 2015, Vol.34(11), pp.2450-2462 [Peer Reviewed Journal]

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Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors

Wang, Wen-Long ; Huang, Chao ; Gao, Li-Xin ; Tang, Chun-Lan ; Wang, Jun-Qing ; Wu, Min-Chen ; Sheng, Li ; Chen, Hai-Jun ; Nan, Fa-Jun ; Li, Jing-Ya ; Li, Jia ; Feng, Bainian

Bioorganic & Medicinal Chemistry Letters, 15 April 2014, Vol.24(8), pp.1889-1894 [Peer Reviewed Journal]

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Recording Evolution Supervised by a Genetic Algorithm for Quantitative Structure-Activity Relationship Optimization

Lorentz Jäntschi ; Sorana D. Bolboacă ; Radu E. Sestraş

Applied Medical Informatics, 01 June 2010, Vol.26(2), pp.89-100 [Peer Reviewed Journal]

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Synthesis and structure-activity relationship studies of novel 3,9-substituted α-carboline derivatives with high cytotoxic activity against colorectal cancer cells

Lin, Yi-Chien ; Chen, Yi-Fong ; Tseng, Li-Shin ; Lee, Yueh-Hsuan ; Morris-Natschke, Susan L ; Kuo, Sheng-Chu ; Yang, Ning-Sun ; Lee, Kuo-Hsiung ; Huang, Li-Jiau

European Journal of Medicinal Chemistry, 03 March 2016, Vol.110, pp.98-114 [Peer Reviewed Journal]

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Design, synthesis and biological evaluation of indolin-2-one-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase3 (FLT3)

Ma, Fei ; Liu, Peng ; Lei, Min ; Liu, Jian ; Wang, Hongtao ; Zhao, Shaohua ; Hu, Lihong

European Journal of Medicinal Chemistry, 15 February 2017, Vol.127, pp.72-86 [Peer Reviewed Journal]

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17
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Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivatives

Xu, Xingyu ; Li, Cong ; Lei, Min ; Zhu, Zhiyuan ; Yan, Jianming ; Shen, Xu ; Hu, Lihong

Bioorganic & Medicinal Chemistry Letters, 01 July 2016, Vol.26(13), pp.2988-2991 [Peer Reviewed Journal]

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18
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Combating breast cancer with non-steroidal aromatase inhibitors (NSAIs): Understanding the chemico-biological interactions through comparative SAR/QSAR study

Adhikari, Nilanjan ; Amin, Sk. Abdul ; Saha, Achintya ; Jha, Tarun

European Journal of Medicinal Chemistry, 08 September 2017, Vol.137, pp.365-438 [Peer Reviewed Journal]

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19
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Synthesis and biological evaluation of novel 3,9-substituted β-carboline derivatives as anticancer agents

Chen, Yi-Fong ; Lin, Yi-Chien ; Chen, Jeng-Pang ; Chan, Hsu-Chin ; Hsu, Mei-Hua ; Lin, Hui-Yi ; Kuo, Sheng-Chu ; Huang, Li-Jiau

Bioorganic & Medicinal Chemistry Letters, 15 September 2015, Vol.25(18), pp.3873-3877 [Peer Reviewed Journal]

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Synthesis and anticancer activity of 2,4-disubstituted furo[3,2-b]indole derivatives

Zhuang, Shi-Hong ; Lin, Yi-Chien ; Chou, Li-Chen ; Hsu, Mei-Hua ; Lin, Hui-Yi ; Huang, Chi-Hung ; Lien, Jin-Cherng ; Kuo, Sheng-Chu ; Huang, Li-Jiau

European Journal of Medicinal Chemistry, August 2013, Vol.66, pp.466-479 [Peer Reviewed Journal]

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21
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Identification of novel chromone based sulfonamides as highly potent and selective inhibitors of alkaline phosphatases

Al-Rashida, Mariya ; Raza, Rabia ; Abbas, Ghulam ; Shah, Muhammad Shakil ; Kostakis, George E ; Lecka, Joanna ; Sévigny, Jean ; Muddassar, Muhammad ; Papatriantafyllopoulou, Constantina ; Iqbal, Jamshed

European Journal of Medicinal Chemistry, August 2013, Vol.66, pp.438-449 [Peer Reviewed Journal]

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22
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Discovery and structure-activity relationships study of thieno[2,3-b]pyridine analogues as hepatic gluconeogenesis inhibitors

Ma, Fei ; Liu, Jian ; Zhou, Tingting ; Lei, Min ; Chen, Jing ; Wang, Xiachang ; Zhang, Yinan ; Shen, Xu ; Hu, Lihong

European Journal of Medicinal Chemistry, 25 May 2018, Vol.152, pp.307-317 [Peer Reviewed Journal]

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23
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Synthesis, preliminary structure–activity relationships, and in vitro biological evaluation of 6-aryl-3-amino-thieno[2,3-b]pyridine derivatives as potential anti-inflammatory agents

Liu, Huan ; Li, Yi ; Wang, Xiang-Ying ; Wang, Bo ; He, Hai-Yun ; Liu, Ji-Yan ; Xiang, Ming-Li ; He, Jun ; Wu, Xiao-Hua ; Yang, Li

Bioorganic & Medicinal Chemistry Letters, 15 April 2013, Vol.23(8), pp.2349-2352 [Peer Reviewed Journal]

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24
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Design, synthesis and 3D-QSAR studies of novel 1,4-dihydropyridines as TGFβ/Smad inhibitors

Längle, Daniel ; Marquardt, Viktoria ; Heider, Elena ; Vigante, Brigita ; Duburs, Gunars ; Luntena, Iveta ; Flötgen, Dirk ; Golz, Christopher ; Strohmann, Carsten ; Koch, Oliver ; Schade, Dennis

European Journal of Medicinal Chemistry, 05 May 2015, Vol.95, pp.249-266 [Peer Reviewed Journal]

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25
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Novel thienopyridine derivatives as specific anti-hepatocellular carcinoma (HCC) agents: Synthesis, preliminary structure–activity relationships, and in vitro biological evaluation

Zeng, Xiu-Xiu ; Zheng, Ren-Lin ; Zhou, Tian ; He, Hai-Yun ; Liu, Ji-Yan ; Zheng, Yu ; Tong, Ai-Ping ; Xiang, Ming-Li ; Song, Xiang-Rong ; Yang, Sheng-Yong ; Yu, Luo-Ting ; Wei, Yu-Quan ; Zhao, Ying-Lan ; Yang, Li

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(21), pp.6282-6285 [Peer Reviewed Journal]

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26
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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/β-catenin signalling pathway agonists

Chen, Duo-Zhi ; Yang, Bi-Juan ; He, Xiao-Li ; Fan, Shi-Rui ; Cai, Jie-Yun ; Jing, Chen-Xu ; Zhang, Heng ; Zhang, Yu ; Li, Lin ; Hao, Xiao-Jiang

Bioorganic Chemistry, March 2019, Vol.84, pp.285-294 [Peer Reviewed Journal]

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27
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New Borrelidins from Onchidium sp. Associated Streptomyces olivaceus SCSIO LO13

Zhou, Zhenbin ; Wu, Qiaoling ; Xie, Qing ; Ling, Chunyao ; Zhang, Hua ; Sun, Changli ; Ju, Jianhua

Chemistry & biodiversity, 26 November 2019 [Peer Reviewed Journal]

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28
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Design, synthesis and evaluation of 2-(4-(substituted benzoyl)-1,4-diazepan-1-yl)-N-phenylacetamide derivatives as a new class of falcipain-2 inhibitors

Mahesh, Radhakrishnan ; Mundra, Sourabh ; Devadoss, Thangaraj ; Kotra, Lakshmi P

Arabian Journal of Chemistry, November 2019, Vol.12(7), pp.1436-1446 [Peer Reviewed Journal]

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29
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Electronic structures and SARs of the isomeric complexes α-, β-, γ- [Ru(mazpy) 2Cl 2] with different antitumor activities

Chen, J.C ; Li, J ; Qian, L ; Zheng, K.C

Journal of Molecular Structure: THEOCHEM, 2005, Vol.728(1), pp.93-101 [Peer Reviewed Journal]

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30
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Predicting toxic action mechanisms of phenols using AdaBoost Learner

Niu, Bing ; Jin, Yuhuan ; Lu, Wencong ; Li, Guozheng

Chemometrics and Intelligent Laboratory Systems, 2009, Vol.96(1), pp.43-48 [Peer Reviewed Journal]

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31
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Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents

Zi, Cheng-Ting ; Yang, Liu ; Xu, Feng-Qing ; Dong, Fa-Wu ; Ma, Rui-Jing ; Li, Yan ; Zhou, Jun ; Ding, Zhong-Tao ; Jiang, Zi-Hua ; Hu, Jiang-Miao

Bioorganic & Medicinal Chemistry Letters, 15 January 2019, Vol.29(2), pp.234-237 [Peer Reviewed Journal]

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32
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Synthesis and biological affinity of new imidazo- and indol-arylpiperazine derivatives: Further validation of a pharmacophore model for α 1-adrenoceptor antagonists

Strappaghetti, Giovannella ; Mastrini, Luciano ; Lucacchini, Antonio ; Giannaccini, Gino ; Betti, Laura ; Fabbrini, Laura

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(18), pp.5140-5145 [Peer Reviewed Journal]

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33
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In vitro dermal absorption rate testing of certain chemicals of interest to the Occupational Safety and Health Administration: Summary and evaluation of USEPA’s mandated testing

Fasano, William J ; Mcdougal, James N

Regulatory Toxicology and Pharmacology, 2008, Vol.51(2), pp.181-194 [Peer Reviewed Journal]

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