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10 Results  for Everything (Includes Articles)

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Practical syntheses of a novel tricyclic dipeptide mimetic based on a [6H]-azepino indoline nucleus: Application to angiotensin-converting enzyme inhibition

De Lombaert, Stéphane ; Blanchard, Louis ; Stamford, Lisa B ; Sperbeck, Donald M ; Grim, Michael D ; Jenson, Todd M ; Rodriguez, Herman R

Tetrahedron Letters, 1994, Vol.35(41), pp.7513-7516 [Peer Reviewed Journal]

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Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety

He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Wu, Zhicai ; Yu, Yang ; Kim, David W ; Ting, Pauline C ; Kuethe, Jeffrey T ; Yang, Ginger X ; Jian, Tianying ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Sperbeck, Donald M ; Sonatore, Lisa M ; Wiltsie, Judyann ; Chung, Christine C ; Gibson, Jack T ; Lisnock, Jeanmarie ; Murphy, Beth A ; Gorski, Judith N ; Liu, Jinqi ; Chen, Dunlu ; Chen, Xiaoli ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; Devita, Robert J

ACS medicinal chemistry letters, 08 August 2013, Vol.4(8), pp.773-8 [Peer Reviewed Journal]

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Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Yang, David X ; Ting, Pauline C ; Kuethe, Jeffrey T ; Cernak, Timothy A ; Dykstra, Kevin D ; Sperbeck, Donald M ; Wu, Zhicai ; Yu, Yang ; Yang, Ginger X ; Jian, Tianying ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Sonatore, Lisa M ; Wiltsie, Judyann ; Liu, Jinqi ; Gorski, Judith N ; Chung, Christine C ; Gibson, Jack T ; Lisnock, Jeanmarie ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; Devita, Robert J

ACS medicinal chemistry letters, 09 October 2014, Vol.5(10), pp.1082-7 [Peer Reviewed Journal]

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( R )-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase
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( R )-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase

Aicher, Thomas D. ; Anderson, Robert C. ; Bebernitz, Gregory R. ; Coppola, Gary M. ; Jewell, Charles F. ; Knorr, Douglas C. ; Liu, Charles ; Sperbeck, Donald M. ; Brand, Leonard J. ; Strohschein, Robert J. ; Gao, Jiaping ; Vinluan, Christine C. ; Shetty, Suraj S. ; Dragland, Carol ; Kaplan, Emma L. ; Delgrande, Dominick ; Islam, Amin ; Liu, Xilin ; Lozito, Robert J. ; Maniara, Wieslawa M. ; Walter, R. Erik ; Mann, William R.

Journal of Medicinal Chemistry, 07/1999, Vol.42(15), pp.2741-2746 [Peer Reviewed Journal]

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Secondary Amides of ( R )-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase
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Secondary Amides of ( R )-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

Aicher, Thomas D. ; Anderson, Robert C. ; Gao, Jiaping ; Shetty, Suraj S. ; Coppola, Gary M. ; Stanton, James L. ; Knorr, Douglas C. ; Sperbeck, Donald M. ; Brand, Leonard J. ; Vinluan, Christine C. ; Kaplan, Emma L. ; Dragland, Carol J. ; Tomaselli, Hollis C. ; Islam, Amin ; Lozito, Robert J. ; Liu, Xilin ; Maniara, Wieslawa M. ; Fillers, William S. ; Delgrande, Dominick ; Walter, R. Eric ; Mann, William R.

Journal of Medicinal Chemistry, 01/2000, Vol.43(2), pp.236-249 [Peer Reviewed Journal]

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The effect of heteroatom substitution on a series of phosphonate inhibitors of neutral endopeptidase 24.11

Stanton, James L ; Ksander, Gary M ; de Jesus, Reynalda ; Sperbeck, Donald M

Bioorganic & Medicinal Chemistry Letters, 1994, Vol.4(4), pp.539-542 [Peer Reviewed Journal]

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Erratum to “Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists” [Bioorg. Med. Chem. Lett. 16 (2006) 4652–4656]

Parker, Dann L ; Meng, Dongfang ; Ratcliffe, Ronald W ; Wilkening, Robert R ; Sperbeck, Donald M ; Greenlee, Mark L ; Colwell, Lawrence F ; Lambert, Sherrie ; Birzin, Elizabeth T ; Frisch, Katalin ; Rohrer, Susan P ; Nilsson, Stefan ; Thorsell, Ann-Gerd ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(20), pp.5472-5472 [Peer Reviewed Journal]

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Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists

Parker, Dann L ; Meng, Dongfang ; Ratcliffe, Ronald W ; Wilkening, Robert R ; Sperbeck, Donald M ; Greenlee, Mark L ; Colwell, Lawrence F ; Lambert, Sherrie ; Birzin, Elizabeth T ; Frisch, Katalin ; Rohrer, Susan P ; Nilsson, Stefan ; Thorsell, Ann-Gerd ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4652-4656 [Peer Reviewed Journal]

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Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC)

Yu, Yang ; Wu, Zhicai ; Shi, Zhi-Cai ; He, Shuwen ; Lai, Zhong ; Cernak, Timothy A ; Vachal, Petr ; Liu, Min ; Liu, Jian ; Hong, Qingmei ; Jian, Tianying ; Guiadeen, Deodial ; Krikorian, Arto ; Sperbeck, Donald M ; Verras, Andreas ; Sonatore, Lisa M ; Murphy, Beth A ; Wiltsie, Judyann ; Chung, Christine C ; Gorski, Judith N ; Liu, Jinqi ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; De Vita, Robert J ; Pinto, Shirly ; Nargund, Ravi P

Bioorganic & Medicinal Chemistry Letters, 01 June 2019, Vol.29(11), pp.1380-1385 [Peer Reviewed Journal]

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Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety

He, Shuwen ; Lai, Zhong ; Hong, Qingmei ; Shang, Jackie ; Reibarkh, Mikhail ; Kuethe, Jeffrey T ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Cernak, Timothy A ; Dykstra, Kevin D ; Sperbeck, Donald M ; Wu, Zhicai ; Yu, Yang ; Yang, Ginger X ; Jian, Tianying ; Verras, Andreas ; Sonatore, Lisa M ; Wiltsie, Judyann ; Chung, Christine C ; Murphy, Beth A ; Gorski, Judith N ; Liu, Jinqi ; Xiao, Jianying ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; Devita, Robert J

Bioorganic & Medicinal Chemistry Letters, 15 May 2019, Vol.29(10), pp.1182-1186 [Peer Reviewed Journal]

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