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Substituted Indole-5-carboxamides and -acetamides as Potent Nonpeptide GnRH Receptor Antagonists

Ashton, Wallace T ; Sisco, Rosemary M ; Yang, Yi Tien ; Lo, Jane-Ling ; Yudkovitz, Joel B ; Cheng, Kang ; Goulet, Mark T

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(13), pp.1723-1726 [Peer Reviewed Journal]

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Dipeptidyl peptidase IV inhibitors derived from β-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole

Ashton, Wallace T ; Sisco, Rosemary M ; Dong, Hong ; Lyons, Kathryn A ; He, Huaibing ; Doss, George A ; Leiting, Barbara ; Patel, Reshma A ; Wu, Joseph K ; Marsilio, Frank ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(9), pp.2253-2258 [Peer Reviewed Journal]

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Diastereoselective synthesis and configuration-dependent activity of (3-substituted-cycloalkyl)glycine pyrrolidides and thiazolidides as dipeptidyl peptidase IV inhibitors

Ashton, Wallace T ; Dong, Hong ; Sisco, Rosemary M ; Doss, George A ; Leiting, Barbara ; Patel, Reshma A ; Wu, Joseph K ; Marsilio, Frank ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 23 February 2004, Vol.14(4), pp.859-863 [Peer Reviewed Journal]

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Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus

Ashton, Wallace T ; Sisco, Rosemary M ; Yang, Yi Tien ; Lo, Jane-Ling ; Yudkovitz, Joel B ; Gibbons, Patrice H ; Mount, George R ; Ren, Rena Ning ; Butler, Bridget S ; Cheng, Kang ; Goulet, Mark T

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(13), pp.1727-1731 [Peer Reviewed Journal]

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Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity

Ashton, Wallace T ; Sisco, Rosemary M ; Kieczykowski, Gerard R ; Yang, Yi Tien ; Yudkovitz, Joel B ; Cui, Jisong ; Mount, George R ; Ren, Rena Ning ; Wu, Tsuei-Ju ; Shen, Xiaolan ; Lyons, Kathryn A ; Mao, An-Hua ; Carlin, Josephine R ; Karanam, Bindhu V ; Vincent, Stella H ; Cheng, Kang ; Goulet, Mark T

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(19), pp.2597-2602 [Peer Reviewed Journal]

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