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23 Results  for Everything (Includes Articles)

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1
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Identification and validation of genes affecting aortic lesions in mice

Yang, Xia ; Peterson, Larry ; Thieringer, Rolf ; Deignan, Joshua L ; Wang, Xuping ; Zhu, Jun ; Wang, Susanna ; Zhong, Hua ; Stepaniants, Serguei ; Beaulaurier, John ; Wang, I-Ming ; Rosa, Ray ; Cumiskey, Anne-Marie ; Luo, Jane Ming-Juan ; Luo, Qi ; Shah, Kashmira ; Xiao, Jianying ; Nickle, David ; Plump, Andrew ; Schadt

The Journal of clinical investigation, July 2010, Vol.120(7), pp.2414-22 [Peer Reviewed Journal]

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Substituted phenyl triazoles as selective inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Sun, Wanying ; Maletic, Milana ; Mundt, Steven S ; Shah, Kashmira ; Zokian, Hratch ; Lyons, Kathy ; Waddell, Sherman T ; Balkovec, James

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(7), pp.2141-2145 [Peer Reviewed Journal]

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Use of Microcomputed Tomography to Measure the Relaxin-induced Expansion of Intrapubic Ligaments in Mice

Zimmerman, Heather A ; Kennan, Richard P ; Zhang, Chunlian ; Shah, Kashmira ; Johns, Douglas G ; Lynch, Joseph J ; Dajee, Maya

Comparative medicine, 01 August 2017, Vol.67(4), pp.330-334 [Peer Reviewed Journal]

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Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome

Maletic, Milana ; Leeman, Aaron ; Szymonifka, Michael ; Mundt, Steven S ; Zokian, Hratch J ; Shah, Kashmira ; Dragovic, Jasminka ; Lyons, Kathy ; Thieringer, Rolf ; Vosatka, Anne H ; Balkovec, James ; Waddell, Sherman T

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(8), pp.2568-2572 [Peer Reviewed Journal]

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Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension

Bauman, David R ; Whitehead, Alan ; Contino, Lisa C ; Cui, Jisong ; Garcia-Calvo, Margarita ; Gu, Xin ; Kevin, Nancy ; Ma, Xiuying ; Pai, Lee-Yuh ; Shah, Kashmira ; Shen, Xiaolan ; Stribling, Sloan ; Zokian, Hratch J ; Metzger, Joe ; Shevell, Diane E ; Waddell, Sherman T

Bioorganic & Medicinal Chemistry Letters, 15 June 2013, Vol.23(12), pp.3650-3653 [Peer Reviewed Journal]

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The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype

Hampton, Caryn ; Zhou, Xiaoyan ; Priest, Birgit T ; Pai, Lee-Yuh ; Felix, John P ; Thomas-Fowlkes, Brande ; Liu, Jessica ; Kohler, Martin ; Xiao, Jianying ; Corona, Aaron ; Price, Olga ; Gill, Charles ; Shah, Kashmira ; Rasa, Cordelia ; Tong, Vince ; Owens, Karen ; Ormes, James ; Tang, Haifeng ; Roy, Sophie ; Sullivan

The Journal of pharmacology and experimental therapeutics, October 2016, Vol.359(1), pp.194-206 [Peer Reviewed Journal]

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11β-HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature

Luo, Mingjuan J ; Thieringer, Rolf ; Springer, Martin S ; Wright, Samuel D ; Hermanowski-Vosatka, Anne ; Plump, Andrew ; Balkovec, James M ; Cheng, Kang ; Ding, Gloria J ; Kawka, Douglas W ; Koo, Gloria C ; Grand, Cheryl B Le ; Luo, Qi ; Maletic, Milana M ; Malkowitz, Lorraine ; Shah, Kashmira ; Singer, Irwin ; Waddell, Sherman T ; Wu, Kenneth K ; Yuan

Physiological genomics, 07 January 2013, Vol.45(1), pp.47-57 [Peer Reviewed Journal]

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Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation

Walsh, Shawn P ; Shahripour, Aurash ; Tang, Haifeng ; Teumelsan, Nardos ; Frie, Jessica ; Zhu, Yuping ; Priest, Birgit T ; Swensen, Andrew M ; Liu, Jessica ; Margulis, Michael ; Visconti, Richard ; Weinglass, Adam ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Alonso-Galicia, Magdalena ; Zhou, Xiaoyan ; Pai, Lee-Yuh ; Corona

ACS medicinal chemistry letters, 09 July 2015, Vol.6(7), pp.747-52 [Peer Reviewed Journal]

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A small molecule very late antigen-4 antagonist can inhibit ovalbumin-induced lung inflammation

Koo, Gloria C ; Shah, Kashmira ; Ding, Gloria J F ; Xiao, Jianying ; Wnek, Richard ; Doherty, George ; Tong, Xin Chun ; Pepinsky, R Blake ; Lin, Ko-Chung ; Hagmann, William K ; Kawka, Douglas ; Singer, Irwin I

American journal of respiratory and critical care medicine, 15 May 2003, Vol.167(10), pp.1400-9 [Peer Reviewed Journal]

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Immunosuppressive effects of a Kv1.3 inhibitor

Shah, Kashmira ; Tom Blake, J ; Huang, Christopher ; Fischer, Paul ; Koo, Gloria C

Cellular Immunology, 2003, Vol.221(2), pp.100-106 [Peer Reviewed Journal]

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Use of a rigid endoscope to teach urethral catheterization of the female dog

Voronin, Gregory ; Porter, William ; Wickham, L ; Gai, Cesaire ; Rasa, Cordelia ; West, Sarah ; Shah, Kashmira

Lab Animal, Aug 2009, Vol.38(8), pp.271-274 [Peer Reviewed Journal]

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4-Methyl-5-phenyl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

Zhu, Yuping ; Olson, Steven H ; Hermanowski-Vosatka, Anne ; Mundt, Steven ; Shah, Kashmira ; Springer, Marty ; Thieringer, Rolf ; Wright, Samuel ; Xiao, Jianying ; Zokian, Hratch ; Balkovec, James M

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(11), pp.3405-3411 [Peer Reviewed Journal]

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Intra-thymic/splenic engraftment of human T cells in HLA-DR1 transgenic NOD/scid mice

Camacho, Ramon E ; Wnek, Richard ; Shah, Kashmira ; Zaller, Dennis M ; O’reilly, Richard J ; Collins, Nancy ; Fitzgerald-Bocarsly, Patricia ; Koo, Gloria C

Cellular Immunology, 2004, Vol.232(1), pp.86-95 [Peer Reviewed Journal]

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14
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Phenylcyclobutyl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

Zhu, Yuping ; Olson, Steven H ; Graham, Donald ; Patel, Gool ; Hermanowski-Vosatka, Anne ; Mundt, Steven ; Shah, Kashmira ; Springer, Marty ; Thieringer, Rolf ; Wright, Samuel ; Xiao, Jianying ; Zokian, Hratch ; Dragovic, Jasminka ; Balkovec, James M

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(11), pp.3412-3416 [Peer Reviewed Journal]

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Characterization of the NOD/scid-[Tg]DR1 mouse expressing HLA-DRB1 ∗01 transgene: a model of SCID-hu mouse for vaccine development

Camacho, Ramon E ; Wnek, Richard ; Fischer, Paul ; Shah, Kashmira ; Zaller, Dennis M ; Woods, Andrea ; La Monica, Nicola ; Aurisicchio, Luigi ; Fitzgerald-Bocarsly, Patricia ; Koo, Gloria C

Experimental Hematology, 2007, Vol.35(8), pp.1219-1230 [Peer Reviewed Journal]

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16
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Bis-aryl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1

Aster, Susan D ; Graham, Donald W ; Kharbanda, Divya ; Patel, Gool ; Ponpipom, Mitree ; Santorelli, Gina M ; Szymonifka, Michael J ; Mundt, Steven S ; Shah, Kashmira ; Springer, Marty S ; Thieringer, Rolf ; Hermanowski-Vosatka, Anne ; Wright, Samuel D ; Xiao, Jianying ; Zokian, Hratch ; Balkovec, James M

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(9), pp.2799-2804 [Peer Reviewed Journal]

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17
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Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: Novel therapeutic agents for the treatment of metabolic syndrome

Gu, Xin ; Dragovic, Jasminka ; Koo, Gloria C ; Koprak, Sam L ; Legrand, Cheryl ; Mundt, Steven S ; Shah, Kashmira ; Springer, Marty S ; Tan, Eugene Y ; Thieringer, Rolf ; Hermanowski-Vosatka, Anne ; Zokian, Hratch J ; Balkovec, James M ; Waddell, Sherman T

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(23), pp.5266-5269 [Peer Reviewed Journal]

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18
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N-Isonicotinoyl-( l)-4-aminophenylalanine derivatives as tight binding VLA-4 antagonists

Doherty, George A ; Yang, Ginger X ; Borges, Edite ; Tong, Sharon ; Mccauley, Ermengilda D ; Treonz, Kelly M ; Van Riper, Gail ; Pacholok, Stephen ; Si, Qian ; Koo, Gloria C ; Shah, Kashmira ; Mumford, Richard A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2003, Vol.13(11), pp.1891-1895 [Peer Reviewed Journal]

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Corrigendum to “ N-Isonicotinoyl-( l)-4-aminophenylalanine Derivatives as Tight Binding VLA-4 Antagonists”[Bioorg. Med. Chem. Lett. 13 (2003) 1891]

Doherty, George A ; Yang, Ginger X ; Borges, Edite ; Tong, Sharon ; Mccauley, Ermengilda D ; Treonz, Kelly M ; Van Riper, Gail ; Pacholok, Stephen ; Si, Qian ; Koo, Gloria C ; Shah, Kashmira ; Mumford, Richard A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2003, Vol.13(17), pp.2937-2938 [Peer Reviewed Journal]

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20
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Potent Kv1.3 inhibitors from correolide—modification of the C18 position

Bao, Jianming ; Miao, Shouwu ; Kayser, Frank ; Kotliar, Andrew J ; Baker, Robert K ; Doss, George A ; Felix, John P ; Bugianesi, Randal M ; Slaughter, Robert S ; Kaczorowski, Gregory J ; Garcia, Maria L ; Ha, Sookhee N ; Castonguay, Laurie ; Koo, Gloria C ; Shah, Kashmira ; Springer, Marty S ; Staruch, Mary Jo ; Parsons, William H ; Rupprecht, Kathleen M

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(2), pp.447-451 [Peer Reviewed Journal]

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21
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Benzamide derivatives as blockers of Kv1.3 ion channel

Miao, Shouwu ; Bao, Jianming ; Garcia, Maria L ; Goulet, Joung L ; Hong, Xingfang J ; Kaczorowski, Gregory J ; Kayser, Frank ; Koo, Gloria C ; Kotliar, Andrew ; Schmalhofer, William A ; Shah, Kashmira ; Sinclair, Peter J ; Slaughter, Robert S ; Springer, Marty S ; Staruch, Mary Jo ; Tsou, Nancy N ; Wong, Frederick ; Parsons, William H ; Rupprecht, Kathleen M

Bioorganic & Medicinal Chemistry Letters, 2003, Vol.13(6), pp.1161-1164 [Peer Reviewed Journal]

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22
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11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice

Hermanowski-Vosatka, Anne ; Balkovec, James M ; Cheng, Kang ; Chen, Howard Y ; Hernandez, Melba ; Koo, Gloria C ; Le Grand, Cheryl B ; Li, Zhihua ; Metzger, Joseph M ; Mundt, Steven S ; Noonan, Heather ; Nunes, Christian N ; Olson, Steven H ; Pikounis, Bill ; Ren, Ning ; Robertson, Nancy ; Schaeffer, James M ; Shah, Kashmira ; Springer, Martin S ; Strack

The Journal of experimental medicine, 15 August 2005, Vol.202(4), pp.517-27 [Peer Reviewed Journal]

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23
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Correolide and Derivatives Are Novel Immunosuppressants Blocking the Lymphocyte Kv1.3 Potassium Channels

Koo, Gloria C ; Blake, Joseph T ; Shah, Kashmira ; Staruch, Mary Jo ; Dumont, Francis ; Wunderler, Denise ; Sanchez, Manuel ; Mcmanus, Owen B ; Sirotina-Meisher, Anna ; Fischer, Paul ; Boltz, Robert C ; Goetz, Michael A ; Baker, Robert ; Bao, Jianming ; Kayser, Frank ; Rupprecht, Kathleen M ; Parsons, William H ; Tong, Xin-Chun ; Ita, Ida E ; Pivnichny, Jim

Cellular Immunology, 01 November 1999, Vol.197(2), pp.99-107 [Peer Reviewed Journal]

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