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Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology

Hauwert, Niels J ; Mocking, Tamara A M ; Da Costa Pereira, Daniel ; Kooistra, Albert J ; Wijnen, Lisa M ; Vreeker, Gerda C M ; Verweij, Eléonore W E ; De Boer, Albertus H ; Smit, Martine J ; De Graaf, Chris ; Vischer, Henry F ; De Esch, Iwan J P ; Wijtmans, Maikel ; Leurs, Rob

Journal of the American Chemical Society, 28 March 2018, Vol.140(12), pp.4232-4243 [Peer Reviewed Journal]

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Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo

Vrontou, Sophia ; Wong, Allan M ; Rau, Kristofer K ; Koerber, H Richard ; Anderson, David J

Nature, 31 January 2013, Vol.493(7434), pp.669-73 [Peer Reviewed Journal]

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A natural variant and engineered mutation in a GPCR promote DEET resistance in C. elegans

Dennis, Emily J ; Dobosiewicz, May ; Jin, Xin ; Duvall, Laura B ; Hartman, Philip S ; Bargmann, Cornelia I ; Vosshall, Leslie B

Nature, October 2018, Vol.562(7725), pp.119-123 [Peer Reviewed Journal]

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Neuroscience. Genetic resolutions of brain convolutions

Rash, Brian G ; Rakic, Pasko

Science (New York, N.Y.), 14 February 2014, Vol.343(6172), pp.744-5 [Peer Reviewed Journal]

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Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis

Wolf, Steffen ; Grünewald, Stefan

PloS one, 2015, Vol.10(4), pp.e0123533 [Peer Reviewed Journal]

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Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support

Di Bartolo, Natalie ; Compton, Emma L R ; Warne, Tony ; Edwards, Patricia C ; Tate, Christopher G ; Schertler, Gebhard F X ; Booth, Paula J

PloS one, 2016, Vol.11(3), pp.e0151582 [Peer Reviewed Journal]

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Identification of the porcine G protein-coupled receptor 41 and 43 genes and their expression pattern in different tissues and development stages

Li, Genlai ; Su, Hao ; Zhou, Zhenjin ; Yao, Wen

PloS one, 2014, Vol.9(5), pp.e97342 [Peer Reviewed Journal]

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Constitutive Activity among Orphan Class-A G Protein Coupled Receptors

Martin, Adam L ; Steurer, Michael A ; Aronstam, Robert S

PloS one, 2015, Vol.10(9), pp.e0138463 [Peer Reviewed Journal]

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A robust and rapid method of producing soluble, stable, and functional G-protein coupled receptors

Corin, Karolina ; Baaske, Philipp ; Ravel, Deepali B ; Song, Junyao ; Brown, Emily ; Wang, Xiaoqiang ; Geissler, Sandra ; Wienken, Christoph J ; Jerabek-Willemsen, Moran ; Duhr, Stefan ; Braun, Dieter ; Zhang, Shuguang

PloS one, 2011, Vol.6(10), pp.e23036 [Peer Reviewed Journal]

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10
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Analysis of LGR4 receptor distribution in human and mouse tissues

Yi, Jing ; Xiong, Wei ; Gong, Xing ; Bellister, Seth ; Ellis, Lee M ; Liu, Qingyun

PloS one, 2013, Vol.8(10), pp.e78144 [Peer Reviewed Journal]

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The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Caruso, Vanni ; Le Grevés, Madeleine ; Shirazi Fard, Shahrzad ; Haitina, Tatjana ; Olszewski, Pawel K ; Alsiö, Johan ; Schiöth, Helgi B ; Fredriksson, Robert

PloS one, 2015, Vol.10(6), pp.e0122061 [Peer Reviewed Journal]

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12
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A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation

Kliewer, Andrea ; Mann, Anika ; Petrich, Aline ; Pöll, Florian ; Schulz, Stefan

PloS one, 2012, Vol.7(6), pp.e39458 [Peer Reviewed Journal]

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Comparative analysis of the heptahelical transmembrane bundles of G protein-coupled receptors

Okada, Tetsuji

PloS one, 2012, Vol.7(4), pp.e35802 [Peer Reviewed Journal]

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14
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Non-redundant coding of aversive odours in the main olfactory pathway

Dewan, Adam ; Pacifico, Rodrigo ; Zhan, Ross ; Rinberg, Dmitry ; Bozza, Thomas

Nature, May 23, 2013, Vol.497(7450), pp.486-9 [Peer Reviewed Journal]

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15
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It's all about the structure

Buchen, Lizzie

Nature, Aug 25, 2011, Vol.476(7361), pp.387-90 [Peer Reviewed Journal]

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16
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New mechanism for voltage induced charge movement revealed in GPCRs--theory and experiments

Zohar, Assaf ; Dekel, Noa ; Rubinsky, Boris ; Parnas, Hanna

PloS one, 22 January 2010, Vol.5(1), pp.e8752 [Peer Reviewed Journal]

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17
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EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells

Li, Jianhua ; Lu, Erick ; Yi, Tangsheng ; Cyster, Jason G

Nature, 05 May 2016, Vol.533(7601), pp.110-4 [Peer Reviewed Journal]

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18
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High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex

Boucard, Antony A ; Ko, Jaewon ; Südhof, Thomas C

The Journal of biological chemistry, 16 March 2012, Vol.287(12), pp.9399-413 [Peer Reviewed Journal]

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19
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An Adaptable Phospholipid Membrane Mimetic System for Solution NMR Studies of Membrane Proteins.

Chien, Chih-Ta Henry ; Helfinger, Lukas R ; Bostock, Mark John ; Solt, Andras ; Tan, Yi Lei ; Nietlispach, Daniel Apollo - University of Cambridge Repository; Apollo - University of Cambridge Repository

2017

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20
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Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor

Biarnés, Xevi ; Marchiori, Alessandro ; Giorgetti, Alejandro ; Lanzara, Carmela ; Gasparini, Paolo ; Carloni, Paolo ; Born, Stephan ; Brockhoff, Anne ; Behrens, Maik ; Meyerhof, Wolfgang

PloS one, 25 August 2010, Vol.5(8), pp.e12394 [Peer Reviewed Journal]

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21
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Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82

Engel, Kathrin M Y ; Schröck, Kristin ; Teupser, Daniel ; Holdt, Lesca Miriam ; Tönjes, Anke ; Kern, Matthias ; Dietrich, Kerstin ; Kovacs, Peter ; Krügel, Ute ; Scheidt, Holger A ; Schiller, Jürgen ; Huster, Daniel ; Brockmann, Gudrun A ; Augustin, Martin ; Thiery, Joachim ; Blüher

PloS one, 2011, Vol.6(12), pp.e29400 [Peer Reviewed Journal]

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22
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Human trace amine-associated receptor TAAR5 can be activated by trimethylamine

Wallrabenstein, Ivonne ; Kuklan, Jonas ; Weber, Lea ; Zborala, Sandra ; Werner, Markus ; Altmüller, Janine ; Becker, Christian ; Schmidt, Anna ; Hatt, Hanns ; Hummel, Thomas ; Gisselmann, Günter

PloS one, 2013, Vol.8(2), pp.e54950 [Peer Reviewed Journal]

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23
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iGPCR-drug: a web server for predicting interaction between GPCRs and drugs in cellular networking

Xiao, Xuan ; Min, Jian-Liang ; Wang, Pu ; Chou, Kuo-Chen

PloS one, 2013, Vol.8(8), pp.e72234 [Peer Reviewed Journal]

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24
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Chemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signalling

Wichard, Jörg D ; Ter Laak, Antonius ; Krause, Gerd ; Heinrich, Nikolaus ; Kühne, Ronald ; Kleinau, Gunnar

PloS one, 04 February 2011, Vol.6(2), pp.e16811 [Peer Reviewed Journal]

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25
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Augmented cardiac hypertrophy in response to pressure overload in mice lacking ELTD1

Xiao, Jinfeng ; Jiang, Hong ; Zhang, Rui ; Fan, Guangpu ; Zhang, Yan ; Jiang, Dingsheng ; Li, Hongliang

PloS one, 2012, Vol.7(5), pp.e35779 [Peer Reviewed Journal]

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26
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Towards improved quality of GPCR models by usage of multiple templates and profile-profile comparison

Latek, Dorota ; Pasznik, Pawel ; Carlomagno, Teresa ; Filipek, Slawomir

PloS one, 2013, Vol.8(2), pp.e56742 [Peer Reviewed Journal]

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27
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In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency

Alvarez-Jaimes, Lily ; Sutton, Steven W ; Nepomuceno, Diane ; Motley, S Timothy ; Cik, Miroslav ; Stocking, Emily ; Shoblock, James ; Bonaventure, Pascal

PloS one, 2012, Vol.7(2), pp.e30792 [Peer Reviewed Journal]

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28
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Label-free phenotypic profiling identified D-luciferin as a GPR35 agonist

Hu, Haibei ; Deng, Huayun ; Fang, Ye

PloS one, 2012, Vol.7(4), pp.e34934 [Peer Reviewed Journal]

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29
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Biosensor-based approach identifies four distinct calmodulin-binding domains in the G protein-coupled estrogen receptor 1

Tran, Quang-Kim ; Vermeer, Mark

PloS one, 2014, Vol.9(2), pp.e89669 [Peer Reviewed Journal]

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30
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Molecular evolution of the neuropeptide S receptor

Pitti, Thejkiran ; Manoj, Narayanan

PloS one, 2012, Vol.7(3), pp.e34046 [Peer Reviewed Journal]

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31
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Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds

Masuda, Katsuyoshi ; Koizumi, Ayako ; Nakajima, Ken-Ichiro ; Tanaka, Takaharu ; Abe, Keiko ; Misaka, Takumi ; Ishiguro, Masaji

PloS one, 2012, Vol.7(4), pp.e35380 [Peer Reviewed Journal]

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32
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A two-step strategy to enhance activity of low potency peptides

Doyle, Jamie R ; Harwood, Benjamin N ; Krishnaji, Subrahmanian Tarakkad ; Krishnamurthy, Vijay M ; Lin, Wei-En ; Fortin, Jean-Philippe ; Kumar, Krishna ; Kopin, Alan S

PloS one, 2014, Vol.9(11), pp.e110502 [Peer Reviewed Journal]

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33
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A population-based approach to study the impact of PROP perception on food liking in populations along the Silk Road

Robino, Antonietta ; Mezzavilla, Massimo ; Pirastu, Nicola ; Dognini, Maddalena ; Tepper, Beverly J ; Gasparini, Paolo

PloS one, 2014, Vol.9(3), pp.e91716 [Peer Reviewed Journal]

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34
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Eco-geographical diversification of bitter taste receptor genes (TAS2Rs) among subspecies of chimpanzees (Pan troglodytes)

Hayakawa, Takashi ; Sugawara, Tohru ; Go, Yasuhiro ; Udono, Toshifumi ; Hirai, Hirohisa ; Imai, Hiroo

PloS one, 2012, Vol.7(8), pp.e43277 [Peer Reviewed Journal]

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35
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Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control

Omori, Yoshihiro ; Chaya, Taro ; Yoshida, Satoyo ; Irie, Shoichi ; Tsujii, Toshinori ; Furukawa, Takahisa

PloS one, 2015, Vol.10(6), pp.e0128422 [Peer Reviewed Journal]

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Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury

Takeda, Norifumi ; Jain, Rajan ; Li, Deqiang ; Li, Li ; Lu, Min Min ; Epstein, Jonathan A

PloS one, 2013, Vol.8(6), pp.e66314 [Peer Reviewed Journal]

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A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents

Luo, Jian ; Swaminath, Gayathri ; Brown, Sean P ; Zhang, Jane ; Guo, Qi ; Chen, Michael ; Nguyen, Kathy ; Tran, Thanhvien ; Miao, Lynn ; Dransfield, Paul J ; Vimolratana, Marc ; Houze, Jonathan B ; Wong, Simon ; Toteva, Maria ; Shan, Bei ; Li, Frank ; Zhuang, Run ; Lin, Daniel C-H

PloS one, 2012, Vol.7(10), pp.e46300 [Peer Reviewed Journal]

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