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12 Results  for Everything (Includes Articles)

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2-(3aR,4R,5S,7aS)-5-{(1S)-1-3,5-bis(trifluoromethyl)phenyl-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro-2H-isoindol-2-yl-1,3-oxazol-4(5H)-one: a potent human NK1 receptor antagonist with multiple clearance pathways

Kassick, Andrew J ; Jiang, Jinlong ; Bunda, Jaime ; Wilson, David ; Bao, Jianming ; Lu, Huagang ; Lin, Peter ; Ball, Richard G ; Doss, George A ; Tong, Xinchun ; Tsao, Kwei-Lan C ; Wang, Hong ; Chicchi, Gary ; Karanam, Bindhu ; Tschirret-Guth, Richard ; Samuel, Koppara ; Hora, Donald F ; Kumar, Sanjeev ; Madeira, Maria ; Eng, Waisi ; Hargreaves, Richard ; Purcell, Mona ; Gantert, Liza ; Cook, Jacquelyn ; Devita, Robert J ; Mills, Sander G

Journal of medicinal chemistry, 25 July 2013, Vol.56(14), pp.5940-8 [Peer Reviewed Journal]

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Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo2,3-cpyridin-1-yl)isoquinolin-5-amine ((18)F-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)

Walji, Abbas M ; Hostetler, Eric D ; Selnick, Harold ; Zeng, Zhizhen ; Miller, Patricia ; Bennacef, Idriss ; Salinas, Cristian ; Connolly, Brett ; Gantert, Liza ; Holahan, Marie ; O'Malley, Stacey ; Purcell, Mona ; Riffel, Kerry ; Li, Jing ; Balsells, Jaume ; Obrien, Julie A ; Melquist, Stacey ; Soriano, Aileen ; Zhang, Xiaoping ; Ogawa, Aimie ; Xu, Serena ; Joshi, Elizabeth ; Della Rocca, Joseph ; Hess, Fred J ; Schachter, Joel ; Hesk, David ; Schenk, David ; Struyk, Arie ; Babaoglu, Kerim ; Lohith, Talakad G ; Wang, Yaode ; Yang, Kun ; Fu, Jianmin ; Evelhoch, Jeffrey L ; Coleman, Paul J

Journal of medicinal chemistry, 26 May 2016, Vol.59(10), pp.4778-89 [Peer Reviewed Journal]

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Evaluation of new PET tracers for in vivo imaging of PD-L1 expression in non-human primate

Rubins, Daniel ; Mcquade, Paul ; Klimas, Michael ; Holahan, Marie ; Purcell, Mona ; Gantert, Liza ; Haley, Hyking ; Lin, Shu-An ; Trotter, Dinko

The Journal of Nuclear Medicine, Feb 1, 2018, Vol.59(2), p.367 [Peer Reviewed Journal]

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A novel method for strict intranasal delivery of non-replicating RSV vaccines in cotton rats and non-human primates

Citron, Michael P ; Patel, Manishkumar ; Purcell, Mona ; Lin, Shu-An ; Rubins, Daniel J ; Mcquade, Paul ; Callahan, Cheryl ; Gleason, Alexa ; Petrescu, Ioan ; Knapp, Walter ; Orekie, Chinedu ; Chamarthy, Sai ; Wen, Zhiyun ; Touch, Sinoeun ; Pine, Matthew ; Fontenot, Jane ; Douglas, Cameron ; Liang, Xiaoping ; Espeseth, Amy S

Vaccine, 11 May 2018, Vol.36(20), pp.2876-2885 [Peer Reviewed Journal]

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Discovery of [11C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors

Cox, Christopher D ; Hostetler, Eric D ; Flores, Broc A ; Evelhoch, Jeffrey L ; Fan, Hong ; Gantert, Liza ; Holahan, Marie ; Eng, Waisi ; Joshi, Aniket ; Mcgaughey, Georgia ; Meng, Xiangjun ; Purcell, Mona ; Raheem, Izzat T ; Riffel, Kerry ; Yan, Youwei ; Renger, John J ; Smith, Sean M ; Coleman, Paul J

Bioorganic & Medicinal Chemistry Letters, 01 November 2015, Vol.25(21), pp.4893-4898 [Peer Reviewed Journal]

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Preclinical Characterization of ^sup 18^F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

Hostetler, Eric ; Walji, Abbas ; Zeng, Zhizhen ; Miller, Patricia ; Bennacef, Idriss ; Salinas, Cristian ; Connolly, Brett ; Gantert, Liza ; Haley, Hyking ; Holahan, Marie ; Purcell, Mona ; Riffel, Kerry ; Lohith, Talakad ; Coleman, Paul ; Soriano, Aileen ; Ogawa, Aimie ; Xu, Serena ; Zhang, Xiaoping ; Joshi, Elizabeth ; Della Rocca, Joseph ; Hesk, David ; Schenk, David ; Evelhoch, Jeffrey

The Journal of Nuclear Medicine, Oct 1, 2016, Vol.57(10), p.1599 [Peer Reviewed Journal]

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Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: a head-to-head comparison with alendronate

Williams, Donald S ; Mccracken, Paul J ; Purcell, Mona ; Pickarski, Maureen ; Mathers, Parker D ; Savitz, Alan T ; Szumiloski, John ; Jayakar, Richa Y ; Somayajula, Sangeetha ; Krause, Stephen ; Brown, Keenan ; Winkelmann, Christopher T ; Scott, Boyd B ; Cook, Lynn ; Motzel, Sherri L ; Hargreaves, Richard ; Evelhoch, Jeffrey L ; Cabal, Antonio ; Dardzinski, Bernard J ; Hangartner, Thomas N ; Duong, Le T

Bone, October 2013, Vol.56(2), pp.489-96 [Peer Reviewed Journal]

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Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: A head-to-head comparison with alendronate

Williams, Donald S ; Mccracken, Paul J ; Purcell, Mona ; Pickarski, Maureen ; Mathers, Parker D ; Savitz, Alan T ; Szumiloski, John ; Jayakar, Richa Y ; Somayajula, Sangeetha ; Krause, Stephen ; Brown, Keenan ; Winkelmann, Christopher T ; Scott, Boyd B ; Cook, Lynn ; Motzel, Sherri L ; Hargreaves, Richard ; Evelhoch, Jeffrey L ; Cabal, Antonio ; Dardzinski, Bernard J ; Hangartner, Thomas N ; Duong, Le T

Bone, October 2013, Vol.56(2), pp.489-496 [Peer Reviewed Journal]

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(11)CMK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor

Bell, Ian M ; Gallicchio, Steven N ; Stump, Craig A ; Bruno, Joseph G ; Fan, Hong ; Gantert, Liza T ; Hostetler, Eric D ; Kemmerer, Amanda L ; Mcwherter, Melody ; Moore, Eric L ; Mosser, Scott D ; Purcell, Mona L ; Riffel, Kerry ; Salvatore, Christopher A ; Sanabria-Bohórquez, Sandra ; Staas, Donnette D ; White, Rebecca B ; Williams, Mangay ; Zartman, C Blair ; Cook, Jacquelynn J ; Hargreaves, Richard J ; Kane, Stefanie A ; Graham, Samuel L ; Selnick, Harold G

ACS medicinal chemistry letters, 12 September 2013, Vol.4(9), pp.863-8 [Peer Reviewed Journal]

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In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer 11CMK-4232

Hostetler, Eric D ; Joshi, Aniket D ; Sanabria-Bohórquez, Sandra ; Fan, Hong ; Zeng, Zhizhen ; Purcell, Mona ; Gantert, Liza ; Riffel, Kerry ; Williams, Mangay ; O'Malley, Stacey ; Miller, Patricia ; Selnick, Harold G ; Gallicchio, Steven N ; Bell, Ian M ; Salvatore, Christopher A ; Kane, Stefanie A ; Li, Chi-Chung ; Hargreaves, Richard J ; De Groot, Tjibbe ; Bormans, Guy ; Van Hecken, Anne ; Derdelinckx, Inge ; De Hoon, Jan ; Reynders, Tom ; Declercq, Ruben ; De Lepeleire, Inge ; Kennedy, W P ; Blanchard, Rebecca ; Marcantonio, Eugene E ; Sur, Cyrille ; Cook, Jacquelynn J ; Van Laere, Koen ; Evelhoch, Jeffrey L

The Journal of pharmacology and experimental therapeutics, November 2013, Vol.347(2), pp.478-86 [Peer Reviewed Journal]

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DISCOVERY AND FIRST-IN-HUMAN EVALUATION OF THE TAU-IMAGING PET RADIOTRACER [18F]MK-6240

Bennacef, Idriss ; Zeng, Zhizhen ; Lohith, Talakad ; Miller, Patricia J ; Salinas, Cristian A ; Connolly, Brett M ; Gantert, Liza T ; Haley, Hyking D ; Marie, Holahan A ; O’malley, Stacey S ; Purcell, Mona L ; Riffel, Kerry ; Coleman, Paul J ; Li, Jing ; Balsells-Padros, Jaume ; Soriano, Aileen ; Ogawa, Aimie M ; Xu, Serena ; Xiaoping, Zhang ; Della Rocca, Joseph ; Schachter, Joel B ; Hesk, David ; David, Schenk J ; Telan-Choing, Florestina ; Struyk, Arie ; Sur, Cyrille ; Celen, Sofie ; Serdons, Kim ; Bormans, Guy ; Vandenbulcke, Mathieu ; Vandenberghe, Rik ; De Hoon, Jan ; Koole, Michel ; Van Laere, Koen ; Declercq, Ruben ; Tom, Reynders ; Abbas, Walji ; Eric, Hostetler D ; Evelhoch, Jeffrey

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, July 2016, Vol.12(7), pp.P501-P502 [Peer Reviewed Journal]

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Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase

Liu, Ping ; Hamill, Terence G ; Chioda, Marc ; Chobanian, Harry ; Fung, Selena ; Guo, Yan ; Chang, Linda ; Bakshi, Raman ; Hong, Qingmei ; Dellureficio, James ; Lin, Linus S ; Abbadie, Catherine ; Alexander, Jessica ; Jin, Hong ; Mandala, Suzanne ; Shiao, Lin-Lin ; Li, Wenping ; Sanabria, Sandra ; Williams, David ; Zeng, Zhizhen ; Hajdu, Richard ; Jochnowitz, Nina ; Rosenbach, Mark ; Karanam, Bindhu ; Madeira, Maria ; Salituro, Gino ; Powell, Joyce ; Xu, Ling ; Terebetski, Jenna L ; Leone, Joseph F ; Miller, Patricia ; Cook, Jacquelynn ; Holahan, Marie ; Joshi, Aniket ; O'Malley, Stacey ; Purcell, Mona ; Posavec, Diane ; Chen, Tsing-Bau ; Riffel, Kerry ; Williams, Mangay ; Hargreaves, Richard ; Sullivan, Kathleen A ; Nargund, Ravi P ; Devita, Robert J

ACS medicinal chemistry letters, 13 June 2013, Vol.4(6), pp.509-13 [Peer Reviewed Journal]

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