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Transition states and energetics of nucleophilic additions of thiols to substituted α,β-unsaturated ketones: substituent effects involve enone stabilization, product branching, and solvation

Krenske, Elizabeth H ; Petter, Russell C ; Zhu, Zhendong ; Houk, K N

The Journal of organic chemistry, 17 June 2011, Vol.76(12), pp.5074-81 [Peer Reviewed Journal]

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Kinetics and Thermodynamics of Reversible Thiol Additions to Mono- and Diactivated Michael Acceptors: Implications for the Design of Drugs That Bind Covalently to Cysteines

Krenske, Elizabeth H ; Petter, Russell C ; Houk, K N

The Journal of organic chemistry, 02 December 2016, Vol.81(23), pp.11726-11733 [Peer Reviewed Journal]

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The Influences of Drug-Resistant Mutations of EGFR to the Inhibitor Binding Affinity and the Drug Target Selectivity Profiles

Park, Jiyong ; Mcdonald, Joseph J ; Petter, Russell C ; Houk, Ken

Biophysical Journal, 16 February 2016, Vol.110(3), pp.544a-544a [Peer Reviewed Journal]

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4
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Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kα

Nacht, Mariana ; Qiao, Lixin ; Sheets, Michael P ; St Martin, Thia ; Labenski, Matthew ; Mazdiyasni, Hormoz ; Karp, Russell ; Zhu, Zhendong ; Chaturvedi, Prasoon ; Bhavsar, Deepa ; Niu, Deqiang ; Westlin, William ; Petter, Russell C ; Medikonda, Aravind Prasad ; Singh, Juswinder

Journal of medicinal chemistry, 14 February 2013, Vol.56(3), pp.712-21 [Peer Reviewed Journal]

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5
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Acylating drugs: redesigning natural covalent inhibitors

Kluge, Arthur F ; Petter, Russell C

Current Opinion in Chemical Biology, 2010, Vol.14(3), pp.421-427 [Peer Reviewed Journal]

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6
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Synthesis of a new analog of proline

Petter, Russell C

Tetrahedron Letters, 1989, Vol.30(4), pp.399-402 [Peer Reviewed Journal]

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7
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The resurgence of covalent drugs

Singh, Juswinder ; Petter, Russell C ; Baillie, Thomas A ; Whitty, Adrian

Nature reviews. Drug discovery, April 2011, Vol.10(4), pp.307-17 [Peer Reviewed Journal]

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8
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Molecular Dynamics Analysis of Binding of Kinase Inhibitors to WT EGFR and the T790M Mutant

Park, Jiyong ; Mcdonald, Joseph J ; Petter, Russell C ; Houk, K N

Journal of chemical theory and computation, 12 April 2016, Vol.12(4), pp.2066-78 [Peer Reviewed Journal]

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9
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Targeted covalent drugs of the kinase family

Singh, Juswinder ; Petter, Russell C ; Kluge, Arthur F

Current Opinion in Chemical Biology, 2010, Vol.14(4), pp.475-480 [Peer Reviewed Journal]

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10
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Lewis-acid catalysis of the asymmetric Diels–Alder reaction of dimenthyl fumarate and cyclopentadiene

Kiesman, William F ; Petter, Russell C

Tetrahedron: Asymmetry, 2002, Vol.13(9), pp.957-960 [Peer Reviewed Journal]

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11
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The effect of tether length on the affinity of ligands for bis(cyclodextrins)

Sikorski, Christopher T ; Petter, Russell C

Tetrahedron Letters, 1994, Vol.35(25), pp.4275-4278 [Peer Reviewed Journal]

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12
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Preparation of 8-substituted xanthine CVT-124 precursor by late stage pyrimidine ring closure

Herr, R Jason ; Vogt, Paul F ; Meckler, Harold ; Trova, Michael P ; Schow, Steven R ; Petter, Russell C

The Journal of organic chemistry, 11 January 2002, Vol.67(1), pp.188-93 [Peer Reviewed Journal]

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13
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Synthesis ofl-2-spirocyclopropyl-2-deoxyarabinose

Petter, Russell C ; Powers, David G

Tetrahedron Letters, 1989, Vol.30(6), pp.659-662 [Peer Reviewed Journal]

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14
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Stereochemistry of directed lithiation of 1,1′-bis(methoxymethyl)ferrocene

Petter, Russell C ; Milberg, Craig I

Tetrahedron Letters, 1989, Vol.30(38), pp.5085-5088 [Peer Reviewed Journal]

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15
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19F NMR monitoring of a S NAr reaction on solid support

Shapiro, Michael J ; Kumaravel, G ; Petter, Russell C ; Beveridge, Richard

Tetrahedron Letters, 1996, Vol.37(27), pp.4671-4674 [Peer Reviewed Journal]

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16
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Application of HMQC in determination of chiral purity using quinine

Shapiro, Michael ; Lin, Mengfen ; Versace, Richard ; Petter, Russell C

Tetrahedron: Asymmetry, 1996, Vol.7(8), pp.2169-2172 [Peer Reviewed Journal]

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17
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Cooperative Dehydration of 1,1′,2,2′-Ferrocenetetramethanol

Petter, Russell C ; Milberg, Craig I ; Jagadishwar Rao, S

Tetrahedron Letters, 1990, Vol.31(43), pp.6117-6120 [Peer Reviewed Journal]

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18
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Norbornyllactone-substituted xanthines as adenosine A 1 receptor antagonists

Kiesman, William F ; Zhao, Jin ; Conlon, Patrick R ; Petter, Russell C ; Jin, Xiaowei ; Smits, Glenn ; Lutterodt, Frank ; Sullivan, Gail W ; Linden, Joel

Bioorganic & Medicinal Chemistry, 2006, Vol.14(11), pp.3654-3661 [Peer Reviewed Journal]

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19
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Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans

Evans, Erica K ; Tester, Richland ; Aslanian, Sharon ; Karp, Russell ; Sheets, Michael ; Labenski, Matthew T ; Witowski, Steven R ; Lounsbury, Heather ; Chaturvedi, Prasoon ; Mazdiyasni, Hormoz ; Zhu, Zhendong ; Nacht, Mariana ; Freed, Martin I ; Petter, Russell C ; Dubrovskiy, Alex ; Singh, Juswinder ; Westlin, William F

The Journal of pharmacology and experimental therapeutics, August 2013, Vol.346(2), pp.219-28 [Peer Reviewed Journal]

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20
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Farnesyl chain modification of squalene synthase inhibitor benzylfarnesylamine: Conversion to the terminal bis(trifluoromethyl) derivative

Jewell, Charles F ; Brinkman, John ; Petter, Russell C ; Wareing, James R

Tetrahedron, 1994, Vol.50(13), pp.3849-3856 [Peer Reviewed Journal]

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21
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Synthesis of 2-spirocyclopropylglucose via condensation of erythrose with the lithium enolate of 2,6-di- tert=butyl-4-methylphenyl cyclopropanecarboxylate

Petter, Russell C ; Kumaravel, G ; Powers, David G ; Chang, Chi-Tai

Tetrahedron Letters, 1991, Vol.32(4), pp.449-452 [Peer Reviewed Journal]

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22
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Tricyclic imidazoline derivatives as potent and selective adenosine A1 receptor antagonists

Vu, Chi B ; Kiesman, William F ; Conlon, Patrick R ; Lin, Ko-Chung ; Tam, Melissa ; Petter, Russell C ; Smits, Glenn ; Lutterodt, Frank ; Jin, Xiaowei ; Chen, Liqing ; Zhang, Jianbo

Journal of medicinal chemistry, 30 November 2006, Vol.49(24), pp.7132-9 [Peer Reviewed Journal]

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23
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Potent and orally bioavailable 8-bicyclo2.2.2octylxanthines as adenosine A1 receptor antagonists

Kiesman, William F ; Zhao, Jin ; Conlon, Patrick R ; Dowling, James E ; Petter, Russell C ; Lutterodt, Frank ; Jin, Xiaowei ; Smits, Glenn ; Fure, Mary ; Jayaraj, Andrew ; Kim, John ; Sullivan, Gail ; Linden, Joel

Journal of medicinal chemistry, 30 November 2006, Vol.49(24), pp.7119-31 [Peer Reviewed Journal]

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24
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Novel diamino derivatives of 1,2,4triazolo1,5-a1,3,5triazine as potent and selective adenosine A2a receptor antagonists

Vu, Chi B ; Pan, Deborah ; Peng, Bo ; Kumaravel, Gnanasambandam ; Smits, Glenn ; Jin, Xiaowei ; Phadke, Deepali ; Engber, Thomas ; Huang, Carol ; Reilly, Jennifer ; Tam, Stacy ; Grant, Donna ; Hetu, Gregg ; Petter, Russell C

Journal of medicinal chemistry, 24 March 2005, Vol.48(6), pp.2009-18 [Peer Reviewed Journal]

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25
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Piperazine derivatives of 1,2,4triazolo1,5-a1,3,5triazine as potent and selective adenosine A2a receptor antagonists

Vu, Chi B ; Peng, Bo ; Kumaravel, Gnanasambandam ; Smits, Glenn ; Jin, Xiaowei ; Phadke, Deepali ; Engber, Thomas ; Huang, Carol ; Reilly, Jennifer ; Tam, Stacy ; Grant, Donna ; Hetu, Gregg ; Chen, Liqing ; Zhang, Jianbo ; Petter, Russell C

Journal of medicinal chemistry, 12 August 2004, Vol.47(17), pp.4291-9 [Peer Reviewed Journal]

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26
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CNS Anticancer Drug Discovery and Development Conference White Paper

Levin, Victor A ; Tonge, Peter J ; Gallo, James M ; Birtwistle, Marc R ; Dar, Arvin C ; Iavarone, Antonio ; Paddison, Patrick J ; Heffron, Timothy P ; Elmquist, William F ; Lachowicz, Jean E ; Johnson, Ted W ; White, Forest M ; Sul, Joohee ; Smith, Quentin R ; Shen, Wang ; Sarkaria, Jann N ; Samala, Ramakrishna ; Wen, Patrick Y ; Berry, Donald A ; Petter, Russell C

Neuro-Oncology, 2015, Vol. 17(suppl6), pp.vi1-vi26 [Peer Reviewed Journal]

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27
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In vitro and in vivo characterization of irreversible mutant-selective EGFR inhibitors that are wild-type sparing

Tjin Tham Sjin, Robert ; Lee, Kwangho ; Walter, Annette O ; Dubrovskiy, Aleksandr ; Sheets, Michael ; Martin, Thia St ; Labenski, Matthew T ; Zhu, Zhendong ; Tester, Richland ; Karp, Russell ; Medikonda, Aravind ; Chaturvedi, Prasoon ; Ren, Yixuan ; Haringsma, Henry ; Etter, Jeff ; Raponi, Mitch ; Simmons, Andrew D ; Harding, Thomas C ; Niu, Deqiang ; Nacht

Molecular cancer therapeutics, June 2014, Vol.13(6), pp.1468-79 [Peer Reviewed Journal]

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28
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Novel bicyclic piperazine derivatives of triazolotriazine and triazolopyrimidines as highly potent and selective adenosine A2A receptor antagonists

Peng, Hairuo ; Kumaravel, Gnanasambandam ; Yao, Gang ; Sha, Li ; Wang, Joy ; Van Vlijmen, Herman ; Bohnert, Tonika ; Huang, Carol ; Vu, Chi B ; Ensinger, Carol L ; Chang, Hexi ; Engber, Thomas M ; Whalley, Eric T ; Petter, Russell C

Journal of medicinal chemistry, 02 December 2004, Vol.47(25), pp.6218-29 [Peer Reviewed Journal]

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29
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Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC

Walter, Annette O ; Sjin, Robert Tjin Tham ; Haringsma, Henry J ; Ohashi, Kadoaki ; Sun, Jing ; Lee, Kwangho ; Dubrovskiy, Aleksandr ; Labenski, Matthew ; Zhu, Zhendong ; Wang, Zhigang ; Sheets, Michael ; St Martin, Thia ; Karp, Russell ; Van Kalken, Dan ; Chaturvedi, Prasoon ; Niu, Deqiang ; Nacht, Mariana ; Petter, Russell C ; Westlin, William ; Lin

Cancer discovery, December 2013, Vol.3(12), pp.1404-15

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30
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Triamino derivatives of triazolotriazine and triazolopyrimidine as adenosine A 2a receptor antagonists

Vu, Chi B ; Shields, Pamela ; Peng, Bo ; Kumaravel, Gnanasambandam ; Jin, Xiaowei ; Phadke, Deepali ; Wang, Joy ; Engber, Thomas ; Ayyub, Eman ; Petter, Russell C

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(19), pp.4835-4838 [Peer Reviewed Journal]

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31
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On-resin macrocyclization of peptides via intramolecular S nAr reactions

Fotsch, Christopher ; Kumaravel, G ; Sharma, Sushil K ; Wu, Arthur D ; Gounarides, John S ; Nirmala, N.R ; Petter, Russell C

Bioorganic & Medicinal Chemistry Letters, 1999, Vol.9(15), pp.2125-2130 [Peer Reviewed Journal]

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32
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Synthesis of [1,2,4]triazolo[1,5- a]pyrazines as adenosine A 2A receptor antagonists

Dowling, James E ; Vessels, Jeffrey T ; Haque, Serajul ; Chang, He Xi ; van Vloten, Kurt ; Kumaravel, Gnanasambandam ; Engber, Thomas ; Jin, Xiaowei ; Phadke, Deepali ; Wang, Joy ; Ayyub, Eman ; Petter, Russell C

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(21), pp.4809-4813 [Peer Reviewed Journal]

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33
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Synthesis of alkyne derivatives of a novel triazolopyrazine as A 2A adenosine receptor antagonists

Yao, Gang ; Haque, Serajul ; Sha, Li ; Kumaravel, Gnanasambandam ; Wang, Joy ; Engber, Thomas M ; Whalley, Eric T ; Conlon, Patrick R ; Chang, Hexi ; Kiesman, William F ; Petter, Russell C

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(3), pp.511-515 [Peer Reviewed Journal]

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34
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Studies on adenosine A 2a receptor antagonists: comparison of three core heterocycles

Vu, Chi B ; Pan, Deborah ; Peng, Bo ; Sha, Li ; Kumaravel, Gnanasambandam ; Jin, Xiaowei ; Phadke, Deepali ; Engber, Thomas ; Huang, Carol ; Reilly, Jennifer ; Tam, Stacy ; Petter, Russell C

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(19), pp.4831-4834 [Peer Reviewed Journal]

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35
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N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model

Baker, Darren P ; Lin, Edward Y ; Lin, Kochung ; Pellegrini, Maria ; Petter, Russell C ; Chen, Ling Ling ; Arduini, Robert M ; Brickelmaier, Margot ; Wen, Dingyi ; Hess, Donna M ; Chen, Liqing ; Grant, Donna ; Whitty, Adrian ; Gill, Alan ; Lindner, Daniel J ; Pepinsky, R Blake

Bioconjugate chemistry, 2006, Vol.17(1), pp.179-88 [Peer Reviewed Journal]

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