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Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC

Piizzi, Grazia ; Parker, David T ; Peng, Yunshan ; Dobler, Markus ; Patnaik, Anup ; Wattanasin, Som ; Liu, Eugene ; Lenoir, Francois ; Nunez, Jill ; Kerrigan, John ; Mckenney, David ; Osborne, Colin ; Yu, Donghui ; Lanieri, Leanne ; Bojkovic, Jade ; Dzink-Fox, Joann ; Lilly, Maria-Dawn ; Sprague, Elizabeth R ; Lu, Yipin ; Wang, Hongming ; Ranjitkar, Srijan ; Xie, Lili ; Wang, Bing ; Glick, Meir ; Hamann, Lawrence G ; Tommasi, Ruben ; Yang, Xia ; Dean, Charles R

Journal of medicinal chemistry, 22 June 2017, Vol.60(12), pp.5002-5014 [Peer Reviewed Journal]

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Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors

Whitehead, Lewis ; Dobler, Markus R ; Radetich, Branko ; Zhu, Yanyi ; Atadja, Peter W ; Claiborne, Tavina ; Grob, Jonathan E ; Mcriner, Andrew ; Pancost, Margaret R ; Patnaik, Anup ; Shao, Wenlin ; Shultz, Michael ; Tichkule, Ritesh ; Tommasi, Ruben A ; Vash, Brian ; Wang, Ping ; Stams, Travis

Bioorganic & Medicinal Chemistry, 2011, Vol.19(15), pp.4626-4634 [Peer Reviewed Journal]

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2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication

Keaney, Erin P ; Connolly, Michael ; Dobler, Markus ; Karki, Rajeshri ; Honda, Ayako ; Sokup, Samantha ; Karur, Subramanian ; Britt, Shawn ; Patnaik, Anup ; Raman, Prakash ; Hamann, Lawrence G ; Wiedmann, Brigitte ; Lamarche, Matthew J

Bioorganic & Medicinal Chemistry Letters, 15 August 2014, Vol.24(16), pp.3714-3718 [Peer Reviewed Journal]

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Identification of orally available naphthyridine protein kinase D inhibitors

Meredith, Erik L ; Ardayfio, Ophelia ; Beattie, Kimberly ; Dobler, Markus R ; Enyedy, Istvan ; Gaul, Christoph ; Hosagrahara, Vinayak ; Jewell, Charles ; Koch, Keith ; Lee, Wendy ; Lehmann, Hansjoerg ; Mckinsey, Timothy A ; Miranda, Karl ; Pagratis, Nikos ; Pancost, Margaret ; Patnaik, Anup ; Phan, Dillon ; Plato, Craig ; Qian, Ming ; Rajaraman, Vasumathy ; Rao, Chang ; Rozhitskaya, Olga ; Ruppen, Thomas ; Shi, Jie ; Siska, Sarah J ; Springer, Clayton ; Van Eis, Maurice ; Vega, Richard B ; Von Matt, Anette ; Yang, Lihua ; Yoon, Taeyoung ; Zhang, Ji-Hu ; Zhu, Na ; Monovich, Lauren G

Journal of medicinal chemistry, 12 August 2010, Vol.53(15), pp.5400-21 [Peer Reviewed Journal]

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Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor

Marro, Martin L ; Patterson, Andrew W ; Lee, Lac ; Deng, Lin ; Reynolds, Aimee ; Ren, Xianglin ; Axford, Laura ; Patnaik, Anup ; Hollis-Symynkywicz, Micah ; Casson, Nigel ; Custeau, Dominique ; Ames, Lisa ; Loi, Sally ; Zhang, Lihe ; Honda, Toshiyuki ; Blank, Jutta ; Harrison, Tyler J ; Papillon, Julien P N ; Hamann, Lawrence G ; Marcinkeviciene, Jovita ; Regard, Jean B

The Journal of pharmacology and experimental therapeutics, October 2018, Vol.367(1), pp.147-154 [Peer Reviewed Journal]

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