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1
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Article
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Orthopedic Sports Injuries in Children and Young Adults

Owens, Karen

Fire Engineering, Mar 2016, Vol.169(3), p.46 [Peer Reviewed Journal]

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2
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Pediatric Seizures

Owens, Karen

Fire Engineering, Feb 2014, Vol.167(2), p.26 [Peer Reviewed Journal]

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3
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Firefighter Burn Injuries

Owens, Karen

Fire Engineering, Apr 2011, Vol.164(4), pp.24,26,28,31-32 [Peer Reviewed Journal]

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4
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Responding to Opioid Overdoses

Owens, Karen

Fire Engineering, Oct 2014, Vol.167(10), p.40 [Peer Reviewed Journal]

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5
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Sports Injuries in Children and Young Adults: Concussions

Owens, Karen

Fire Engineering, Oct 2015, Vol.168(10), p.28 [Peer Reviewed Journal]

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6
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Patient Care Reports and NEMSIS

Owens, Karen

Fire Engineering, Apr 2017, Vol.170(4), p.44 [Peer Reviewed Journal]

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7
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Treatment/Transport of Bariatric Patients

Owens, Karen

Fire Engineering, May 2012, Vol.165(5), pp.28,30-31 [Peer Reviewed Journal]

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8
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The Role of the Therapeutic Alliance in the Regulation of Emotion in Psychosis: An Attachment Perspective

Owens, Karen Annette ; Haddock, Gillian ; Berry, Katherine

Clinical Psychology & Psychotherapy, November 2013, Vol.20(6), pp.523-530 [Peer Reviewed Journal]

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9
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Miscarriage Recognition and Treatment

Owens, Karen

Fire Engineering, Jul 2009, Vol.162(7), pp.24,26-28 [Peer Reviewed Journal]

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10
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Patient Care During Extrication

Owens, Karen

Fire Engineering, Nov 2009, Vol.162(11), pp.22,24,26-27 [Peer Reviewed Journal]

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11
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EMS Triage: Sorting Through the Maze

Owens, Karen

Fire Engineering, Mar 2008, Vol.161(3), pp.155-156,158-160,162 [Peer Reviewed Journal]

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12
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Enhanced External Counterpulsation Treatment Improves Arterial Wall Properties and Wave Reflection Characteristics in Patients With Refractory Angina

Nichols, Wilmer W ; Estrada, Juan C ; Braith, Randy W ; Owens, Karen ; Conti, C. Richard

Journal of the American College of Cardiology, 19 September 2006, Vol.48(6), pp.1208-1214 [Peer Reviewed Journal]

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13
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Article
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Recycling: It's Not Just For Environmentalists

Owens, Karen

Business and Economic Review, Jan-Mar 2005, Vol.51(2), pp.9-12 [Peer Reviewed Journal]

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14
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Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques

Wickham, L. Alexandra ; Sitko, Gary ; Stranieri-Michener, Maria ; Handt, Larry ; Basso, Andrea ; Fried, Steven ; Chu, Lin ; Maderia, Maria ; Owens, Karen ; Castriota, Gino ; Chen, Zhu ; Metzger, Joseph M ; Imbriglio, Jason ; Wang, Xinkang ; Cai, Tian-Quan

Thrombosis Research, September 2016, Vol.145, pp.133-139 [Peer Reviewed Journal]

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15
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Characterization of multidrug resistance 1a/P-glycoprotein knockout rats generated by zinc finger nucleases

Chu, Xiaoyan ; Zhang, Zuo ; Yabut, Jocelyn ; Horwitz, Sarah ; Levorse, John ; Li, Xiang-Qing ; Zhu, Lei ; Lederman, Harmony ; Ortiga, Rachel ; Strauss, John ; Li, Xiaofang ; Owens, Karen A ; Dragovic, Jasminka ; Vogt, Thomas ; Evers, Raymond ; Shin, Myung K

Molecular pharmacology, February 2012, Vol.81(2), pp.220-7 [Peer Reviewed Journal]

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16
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Extending the Reach of Pediatric Emergency Preparedness: A Virtual Tabletop Exercise Targeting Children’s Needs

So, Marvin ; Dziuban, Eric J ; Franks, Jessica L ; Cobham-Owens, Karen ; Schonfeld, David J ; Gardner, Aaron H ; Krug, Steven E ; Peacock, Georgina ; Chung, Sarita

Public Health Reports, July 2019, Vol.134(4), pp.344-353 [Peer Reviewed Journal]

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17
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A landscape level comparison of pre-European settlement and current soil carbon content of a forested landscape in upper Michigan

Owens, Karen E ; Reed, David D ; Londo, Andrew J ; Maclean, Ann L ; Mroz, Glenn D

Forest Ecology and Management, 1999, Vol.113(2), pp.179-189 [Peer Reviewed Journal]

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18
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Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans

Chu, Xiaoyan ; Shih, Shian-Jiun ; Shaw, Rachel ; Hentze, Hannes ; Chan, Grace H ; Owens, Karen ; Wang, Shubing ; Cai, Xiaoxin ; Newton, Deborah ; Castro-Perez, Jose ; Salituro, Gino ; Palamanda, Jairam ; Fernandis, Aaron ; Ng, Choon Keow ; Liaw, Andy ; Savage, Mary J ; Evers, Raymond

Drug metabolism and disposition: the biological fate of chemicals, June 2015, Vol.43(6), pp.851-63 [Peer Reviewed Journal]

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19
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Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one

Tang, Haifeng ; de Jesus, Reynald K ; Walsh, Shawn P ; Zhu, Yuping ; Yan, Yan ; Priest, Birgit T ; Swensen, Andrew M ; Alonso-Galicia, Magdalena ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Zhou, Xiaoyan ; Pai, Lee-Yuh ; Hampton, Caryn ; Hernandez, Melba ; Owens, Karen ; Roy, Sophie ; Kaczorowski, Gregory J ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 01 November 2013, Vol.23(21), pp.5829-5832 [Peer Reviewed Journal]

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20
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Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores

Dong, Shuzhi ; Vangelder, Kelsey ; Shi, Zhi-Cai ; Yu, Yang ; Wu, Zhicai ; Ferguson, Ron ; Guo, Zack Zhiqiang ; Tang, Haifeng ; Frie, Jessica ; Fu, Qinghong ; Gu, Xin ; Priest, Birgit T ; Thomas-Fowlkes, Brande ; Weinglass, Adam ; Margulis, Michael ; Liu, Jessica ; Pai, Lee-Yuh ; Hampton, Caryn ; Haimbach, Robin E ; Owens, Karen

Bioorganic & Medicinal Chemistry Letters, 01 June 2017, Vol.27(11), pp.2559-2566 [Peer Reviewed Journal]

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21
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Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure

Tang, Haifeng ; Zhu, Yuping ; Teumelsan, Nardos ; Walsh, Shawn P ; Shahripour, Aurash ; Priest, Birgit T ; Swensen, Andrew M ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Pai, Lee-Yuh ; Hampton, Caryn ; Corona, Aaron ; Hernandez, Melba ; Metzger, Joseph ; Forrest, Michael ; Zhou, Xiaoyan ; Owens, Karen ; Tong

ACS medicinal chemistry letters, 14 July 2016, Vol.7(7), pp.697-701 [Peer Reviewed Journal]

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22
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The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics

Chobanian, Harry R ; Guo, Yan ; Pio, Barbara ; Tang, Haifeng ; Teumelsan, Nardos ; Clements, Matthew ; Frie, Jessica ; Ferguson, Ronald ; Guo, Zach ; Thomas-Fowlkes, Brande S ; Felix, John P ; Liu, Jessica ; Kohler, Martin ; Priest, Birgit ; Hampton, Caryn ; Pai, Lee-Yuh ; Corona, Aaron ; Metzger, Joseph ; Tong, Vincent ; Joshi

Bioorganic & medicinal chemistry letters, 15 February 2017, Vol.27(4), pp.1109-1114 [Peer Reviewed Journal]

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23
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Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporation

Walsh, Shawn P ; Shahripour, Aurash ; Tang, Haifeng ; de Jesus, Reynalda K ; Teumelsan, Nardos ; Zhu, Yuping ; Frie, Jessica ; Priest, Birgit T ; Swensen, Andrew M ; Alonso-Galicia, Magdalena ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Zhou, Xiaoyan ; Pai, Lee-Yuh ; Hampton, Caryn ; Hernandez, Melba ; Owens, Karen ; Ehrhart, Juliann

Bioorganic & Medicinal Chemistry Letters, 01 May 2016, Vol.26(9), pp.2339-2343 [Peer Reviewed Journal]

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24
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Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation

O'Keefe, Stephen J ; Mudgett, John S ; Cupo, Susan ; Parsons, Janey N ; Chartrain, Nicole A ; Fitzgerald, Catherine ; Chen, Shiow-Ling ; Lowitz, Karen ; Rasa, Cordelia ; Visco, Denise ; Luell, Silvi ; Carballo-Jane, Ester ; Owens, Karen ; Zaller, Dennis M

The Journal of biological chemistry, 30 November 2007, Vol.282(48), pp.34663-71 [Peer Reviewed Journal]

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25
Synthesis of Nodulisporic Acid 2‘ ‘-Oxazoles and 2‘ ‘-Thiazoles
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Synthesis of Nodulisporic Acid 2‘ ‘-Oxazoles and 2‘ ‘-Thiazoles

Berger, Richard ; Shoop, Wesley L. ; Pivnichny, James V. ; Warmke, Lynn M. ; Zakson-Aiken, Michelle ; Owens, Karen A. ; Demontigny, Pierre ; Schmatz, Dennis M. ; Wyvratt, Matthew J. ; Fisher, Michael H. ; Meinke, Peter T. ; Colletti, Steven L.

Organic Letters, 11/2001, Vol.3(23), pp.3715-3718 [Peer Reviewed Journal]

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26
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The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype

Hampton, Caryn ; Zhou, Xiaoyan ; Priest, Birgit T ; Pai, Lee-Yuh ; Felix, John P ; Thomas-Fowlkes, Brande ; Liu, Jessica ; Kohler, Martin ; Xiao, Jianying ; Corona, Aaron ; Price, Olga ; Gill, Charles ; Shah, Kashmira ; Rasa, Cordelia ; Tong, Vince ; Owens, Karen ; Ormes, James ; Tang, Haifeng ; Roy, Sophie ; Sullivan

The Journal of pharmacology and experimental therapeutics, October 2016, Vol.359(1), pp.194-206 [Peer Reviewed Journal]

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27
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Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics

Tang, Haifeng ; Walsh, Shawn P ; Yan, Yan ; De Jesus, Reynalda K ; Shahripour, Aurash ; Teumelsan, Nardos ; Zhu, Yuping ; Ha, Sookhee ; Owens, Karen A ; Thomas-Fowlkes, Brande S ; Felix, John P ; Liu, Jessica ; Kohler, Martin ; Priest, Birgit T ; Bailey, Timothy ; Brochu, Richard ; Alonso-Galicia, Magdalena ; Kaczorowski, Gregory J ; Roy, Sophie ; Yang

ACS medicinal chemistry letters, 10 May 2012, Vol.3(5), pp.367-72 [Peer Reviewed Journal]

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28
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Pharmacologic inhibition of the renal outer medullary potassium channel causes diuresis and natriuresis in the absence of kaliuresis

Garcia, Maria L ; Priest, Birgit T ; Alonso-Galicia, Magdalena ; Zhou, Xiaoyan ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Liu, Jessica ; Swensen, Andrew ; Pai, Lee-Yuh ; Xiao, Jianying ; Hernandez, Melba ; Hoagland, Kimberly ; Owens, Karen ; Tang, Haifeng ; De Jesus, Reynalda K ; Roy, Sophie ; Kaczorowski, Gregory J ; Pasternak

The Journal of pharmacology and experimental therapeutics, January 2014, Vol.348(1), pp.153-64 [Peer Reviewed Journal]

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29
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Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino2,1-c1,4oxazine scaffold

Zhu, Yuping ; De Jesus, Reynalda K ; Tang, Haifeng ; Walsh, Shawn P ; Jiang, Jinlong ; Gu, Xin ; Teumelsan, Nardos ; Shahripour, Aurash ; Pio, Barbara ; Ding, Fa-Xiang ; Ha, Sookhee ; Priest, Birgit T ; Swensen, Andrew M ; Alonso-Galicia, Magdalena ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Zhou, Xiaoyan ; Pai

Bioorganic & medicinal chemistry letters, 01 December 2016, Vol.26(23), pp.5695-5702 [Peer Reviewed Journal]

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30
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Writing a winning process change proposal

Ames, Heide ; Owens, Karen

Healthcare Purchasing News, Jan 2020, Vol.44(1), pp.36-38

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31
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Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities

Tang, Haifeng ; Yan, Yan ; Feng, Zhe ; de Jesus, Reynalda K ; Yang, Lihu ; Levorse, Dorothy A ; Owens, Karen A ; Akiyama, Taro E ; Bergeron, Raynald ; Castriota, Gino A ; Doebber, Thomas W ; Ellsworth, Kenneth P ; Lassman, Michael E ; Li, Cai ; Wu, Margaret S ; Zhang, Bei B ; Chapman, Kevin T ; Mills, Sander G ; Berger, Joel P ; Pasternak, Alexander

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(20), pp.6088-6092 [Peer Reviewed Journal]

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32
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Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-4-(2-18Ffluoroethoxy)phenyl-1-methylpropyl}- 2-methyl-2-(5-methylpyridin-2-yl)oxypropanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use

Liu, Ping ; Lin, Linus S ; Hamill, Terence G ; Jewell, James P ; Lanza, Thomas J ; Gibson, Raymond E ; Krause, Stephen M ; Ryan, Christine ; Eng, Waisi ; Sanabria, Sandra ; Tong, Xinchun ; Wang, Junying ; Levorse, Dorothy A ; Owens, Karen A ; Fong, Tung M ; Shen, Chun-Pyn ; Lao, Julie ; Kumar, Sanjeev ; Yin, Wenji ; Payack

Journal of medicinal chemistry, 26 July 2007, Vol.50(15), pp.3427-30 [Peer Reviewed Journal]

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33
Software Development Standard for Mission Critical Systems
Material Type:
Technical Report
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Software Development Standard for Mission Critical Systems

Adams, Richard J ; Eslinger, Suellen ; Owens, Karen L ; Tagami, Joanne M ; Zambrana, Michael A Aerospace Corp El Segundo Ca (Corporate Author)

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34
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Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation

Walsh, Shawn P ; Shahripour, Aurash ; Tang, Haifeng ; Teumelsan, Nardos ; Frie, Jessica ; Zhu, Yuping ; Priest, Birgit T ; Swensen, Andrew M ; Liu, Jessica ; Margulis, Michael ; Visconti, Richard ; Weinglass, Adam ; Felix, John P ; Brochu, Richard M ; Bailey, Timothy ; Thomas-Fowlkes, Brande ; Alonso-Galicia, Magdalena ; Zhou, Xiaoyan ; Pai, Lee-Yuh ; Corona

ACS medicinal chemistry letters, 09 July 2015, Vol.6(7), pp.747-52 [Peer Reviewed Journal]

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35
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Nucleophilic substitution in organomercury halides by a free radical chain process

Russel, Glen A ; Hershberger, James ; Owens, Karen

Journal of Organometallic Chemistry, 1982, Vol.225(1), pp.43-56 [Peer Reviewed Journal]

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36
Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides
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Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides

Esser, Craig K. ; Bugianesi, Robert L. ; Caldwell, Charles G. ; Chapman, Kevin T. ; Durette, Philippe L. ; Girotra, Narindar N. ; Kopka, Ihor E. ; Lanza, Thomas J. ; Levorse, Dorothy A. ; Maccoss, Malcolm ; Owens, Karen A. ; Ponpipom, Mitree M. ; Simeone, Joseph P. ; Harrison, Richard K. ; Niedzwiecki, Lisa ; Becker, Joseph W. ; Marcy, Alice I. ; Axel, Melinda G. ; Christen, Amy J. ; Mcdonnell

Journal of Medicinal Chemistry, 03/1997, Vol.40(6), pp.1026-1040 [Peer Reviewed Journal]

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