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12 Results  for Everything (Includes Articles)

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Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder

Nygren, Patrick J ; Scott, John D

Frontiers in pharmacology, 2015, Vol.6, pp.158 [Peer Reviewed Journal]

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Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jiménez Caliani, Antonio Javier ; Langeberg, Lorene K. ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell'Acqua, Mark L ; Santana, L Fernando ; Scott, John D.

EMBO journal: European Molecular Biology Organization, 2012, Issue 20, pp.3991-4004 [Peer Reviewed Journal]

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Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jimenez‐Caliani, Antonio J ; Langeberg, Lorene K ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell' Acqua, Mark L ; Santana, L Fernando ; Scott, John D

EMBO Journal, 17 October 2012, Vol.31(20), pp.3991-4004 [Peer Reviewed Journal]

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Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A ; Navedo, Manuel F ; Ulman, Allison ; Whiting, Jennifer L ; Nygren, Patrick J ; Tian, Geng ; Jimenez‐Caliani, Antonio J ; Langeberg, Lorene K ; Cirulli, Vincenzo ; Tengholm, Anders ; Dell' Acqua, Mark L ; Fernando Santana, L ; Scott, John D

EMBO Journal, 28 November 2012, Vol.31(23), pp.4481-4481 [Peer Reviewed Journal]

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Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220

Whiting, Jennifer L ; Nygren, Patrick J ; Tunquist, Brian J ; Langeberg, Lorene K ; Seternes, Ole-Morten ; Scott, John D

The Journal of biological chemistry, 07 August 2015, Vol.290(32), pp.19445-57 [Peer Reviewed Journal]

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Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex

Gold, Matthew G ; Stengel, Florian ; Nygren, Patrick J ; Weisbrod, Chad R ; Bruce, James E ; Robinson, Carol V ; Barford, David ; Scott, John D

Proceedings of the National Academy of Sciences of the United States of America, 19 April 2011, Vol.108(16), pp.6426-31 [Peer Reviewed Journal]

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Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity

Nygren, Patrick J ; Mehta, Sohum ; Schweppe, Devin K ; Langeberg, Lorene K ; Whiting, Jennifer L ; Weisbrod, Chad R ; Bruce, James E ; Zhang, Jin ; Veesler, David ; Scott, John D

eLife, 02 October 2017, Vol.6 [Peer Reviewed Journal]

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Local protein kinase A action proceeds through intact holoenzymes

Smith, F Donelson ; Esseltine, Jessica L ; Nygren, Patrick J ; Veesler, David ; Byrne, Dominic P ; Vonderach, Matthias ; Strashnov, Ilya ; Eyers, Claire E ; Eyers, Patrick A ; Langeberg, Lorene K ; Scott, John D

Science (New York, N.Y.), 23 June 2017, Vol.356(6344), pp.1288-1293 [Peer Reviewed Journal]

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AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K+ currents in ventricular myocytes following myocardial infarction

Nieves-Cintrón, Madeline ; Hirenallur-Shanthappa, Dinesh ; Nygren, Patrick J ; Hinke, Simon A ; Dell'Acqua, Mark L ; Langeberg, Lorene K ; Navedo, Manuel ; Santana, Luis F ; Scott, John D

Cellular Signalling, July 2016, Vol.28(7), pp.733-740 [Peer Reviewed Journal]

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A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors

Samelson, Bret K ; Gore, Bryan B ; Whiting, Jennifer L ; Nygren, Patrick J ; Purkey, Alicia M ; Colledge, Marcie ; Langeberg, Lorene K ; Dell'Acqua, Mark L ; Zweifel, Larry S ; Scott, John D

The Journal of biological chemistry, 29 May 2015, Vol.290(22), pp.14107-19 [Peer Reviewed Journal]

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Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins

Smith, F Donelson ; Omar, Mitchell H ; Nygren, Patrick J ; Soughayer, Joseph ; Hoshi, Naoto ; Lau, Ho-Tak ; Snyder, Calvin G ; Branon, Tess C ; Ghosh, Debapriya ; Langeberg, Lorene K ; Ting, Alice Y ; Santana, Luis F ; Ong, Shao-En ; Navedo, Manuel F ; Scott, John D

Proceedings of the National Academy of Sciences of the United States of America, 04 December 2018, Vol.115(49), pp.E11465-E11474 [Peer Reviewed Journal]

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AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus

Nystoriak, Matthew A ; Nieves-Cintrón, Madeline ; Nygren, Patrick J ; Hinke, Simon A ; Nichols, C Blake ; Chen, Chao-Yin ; Puglisi, Jose L ; Izu, Leighton T ; Bers, Donald M ; Dell'Acqua, Mark L ; Scott, John D ; Santana, Luis F ; Navedo, Manuel F

Circulation research, 14 February 2014, Vol.114(4), pp.607-15 [Peer Reviewed Journal]

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