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19 Results  for Everything (Includes Articles)

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Drug review: Fosaprepitant

Radhakrishnan, Venkatraman

Indian Journal of Medical and Paediatric Oncology, 2019, Vol.40(1), p.132-135 [Peer Reviewed Journal]

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Evaluating the role of substance P in the growth of brain tumors

Harford-Wright, E ; Lewis, K.M ; Vink, R ; Ghabriel, M.N

Neuroscience, 07 March 2014, Vol.261, pp.85-94 [Peer Reviewed Journal]

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Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands

Vardanyan, Ruben ; Kumirov, Vlad K ; Nichol, Gary S ; Davis, Peg ; Liktor-Busa, Erika ; Rankin, David ; Varga, Eva ; Vanderah, Todd ; Porreca, Frank ; Lai, Josephine ; Hruby, Victor J

Bioorganic & Medicinal Chemistry, 2011, Vol.19(20), pp.6135-6142 [Peer Reviewed Journal]

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Intra-articular administration of tachykinin NK1 receptor antagonists reduces hyperalgesia and cartilage destruction in the inflammatory joint in rats with adjuvant-induced arthritis

Uematsu, Takuya ; Sakai, Atsushi ; Ito, Hiromoto ; Suzuki, Hidenori

European Journal of Pharmacology, 01 October 2011, Vol.668(1-2), pp.163-168 [Peer Reviewed Journal]

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5
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Rolapitant (SCH 619734): A potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets

Duffy, Ruth A ; Morgan, Cynthia ; Naylor, Robert ; Higgins, Guy A ; Varty, Geoffrey B ; Lachowicz, Jean E ; Parker, Eric M

Pharmacology, Biochemistry and Behavior, July 2012, Vol.102(1), pp.95-100 [Peer Reviewed Journal]

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The preventive effect of the impaired liver function for antiemetic therapy against chemotherapy-induced nausea and vomiting in hepatocellular carcinoma patients

Nishikawa, Tomohiro ; Asai, Akira ; Okamoto, Norio ; Yasuoka, Hidetaka ; Nakamura, Ken ; Yokohama, Keisuke ; Ohama, Hideko ; Tsuchimoto, Yusuke ; Fukunishi, Shinya ; Tsuda, Yasuhiro ; Yamamoto, Kazuhiro ; Higuchi, Kazuhide

Journal of clinical biochemistry and nutrition, November 2017, Vol.61(3), pp.222-227 [Peer Reviewed Journal]

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7
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Targeting classical but not neurogenic inflammation reduces peritumoral oedema in secondary brain tumours

Lewis, Kate M ; Harford-Wright, Elizabeth ; Vink, Robert ; Ghabriel, Mounir N

Journal of Neuroimmunology, 15 September 2012, Vol.250(1-2), pp.59-65 [Peer Reviewed Journal]

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8
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Cholera Toxin Induces Sustained Hyperexcitability in Myenteric, but Not Submucosal, AH Neurons in Guinea Pig Jejunum

Joel C. Bornstein ; Katerina Koussoulas ; Rachel M. Gwynne ; Jaime P. P. Foong

Frontiers in Physiology, 01 April 2017, Vol.8 [Peer Reviewed Journal]

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9
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Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: a randomized, double-blind study

Rapoport, Bernardo ; Jordan, Karin ; Boice, Judith ; Taylor, Arlene ; Brown, Carole ; Hardwick, James ; Carides, Alexandra ; Webb, Timothy ; Schmoll, Hans-Joachim

Supportive Care in Cancer, 2010, Vol.18(4), pp.423-431 [Peer Reviewed Journal]

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Cerebral Blood Flow Changes After Treatment of Social Phobia with the Neurokinin-1 Antagonist GR205171, Citalopram, or Placebo

Furmark, Tomas ; Appel, Lieuwe ; Michelgård, Åsa ; Wahlstedt, Kurt ; Åhs, Fredrik ; Zancan, Stefano ; Jacobsson, Eva ; Flyckt, Karin ; Grohp, Magnus ; Bergström, Mats ; Pich, Emilio Merlo ; Nilsson, Lars-Göran ; Bani, Massimo ; Långström, Bengt ; Fredrikson, Mats

Biological Psychiatry, 2005, Vol.58(2), pp.132-142 [Peer Reviewed Journal]

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Analysis of crucial structural requirements of 2-substituted pyrimido[4,5- b][1,5]oxazocines as NK 1 receptor antagonist by axially chiral derivatives

Seto, Shigeki ; Asano, Jun

Bioorganic & Medicinal Chemistry, 2007, Vol.15(15), pp.5083-5089 [Peer Reviewed Journal]

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12
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The oral NK1 antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: a combined analysis of two randomised, placebo-controlled phase III clinical trials

de Wit, R ; Herrstedt, J ; Rapoport, B ; Carides, A.D ; Guoguang-Ma, J ; Elmer, M ; Schmidt, C ; Evans, J.K ; Horgan, K.J

European Journal of Cancer, February 2004, Vol.40(3), pp.403-410 [Peer Reviewed Journal]

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Localization and activation of substance P receptors in unmyelinated axons of rat glabrous skin

Carlton, Susan M ; Zhou, Shengtai ; Coggeshall, Richard E

Brain Research, 23 September 1996, Vol.734(1-2), pp.103-108 [Peer Reviewed Journal]

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Effects of RPR 100893, a potent NK1 antagonist, on the jaw-opening reflex in the guinea pig

Alia, S ; Azérad, J ; Pollin, B

Brain Research, 1998, Vol.787(1), pp.99-106 [Peer Reviewed Journal]

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15
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Aprepitant in adolescent patients for prevention of chemotherapy‐induced nausea and vomiting: A randomized, double‐blind, placebo‐controlled study of efficacy and tolerability

Gore, Lia ; Chawla, Sant ; Petrilli, Antonio ; Hemenway, Molly ; Schissel, Debra ; Chua, Vickey ; Carides, Alexandra D. ; Taylor, Arlene ; Devandry, Suzanne ; Valentine, Jack ; Evans, Judith K. ; Oxenius, Bettina

Pediatric Blood & Cancer, February 2009, Vol.52(2), pp.242-247 [Peer Reviewed Journal]

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Cyclopentane-based human NK1 antagonists. Part 1: Discovery and initial SAR

Finke, Paul E ; Meurer, Laura C ; Levorse, Dorothy A ; Mills, Sander G ; Maccoss, Malcolm ; Sadowski, Sharon ; Cascieri, Margaret A ; Tsao, Kwei-Lan ; Chicchi, Gary G ; Metzger, Joseph M ; Macintyre, D. Euan

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4497-4503 [Peer Reviewed Journal]

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17
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Aprepitant in Anti-histamine-refractory Chronic Nodular Prurigo: A Multicentre, Randomized, Double-blind, Placebo-controlled, Cross-over, Phase-II trial (APREPRU)

Athanasios Tsianakas ; Claudia Zeidler ; Claudia Riepe ; Matthias Borowski ; Caroline Forner ; Joachim Gerss ; Martin Metz ; Petra Staubach ; Ulrike Raap ; Martin Kaatz ; Marc Urban ; Thomas A. Luger ; Sonja Ständer

Acta Dermato-Venereologica, 01 February 2019, Vol.99(4), pp.379-385 [Peer Reviewed Journal]

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Pharmacological characterization of desensitization in scratching behavior induced by intrathecal administration of hemokinin-1 in the rat

Naono, R ; Nakayama, T ; Ikeda, T ; Matsusima, O ; Nishimori, T

Neuropeptides, 2008, Vol.42(1), pp.47-55 [Peer Reviewed Journal]

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Cyclopentane-based human NK1 antagonists. Part 2: Development of potent, orally active, water-soluble derivatives

Meurer, Laura C ; Finke, Paul E ; Owens, Karen A ; Tsou, Nancy N ; Ball, Richard G ; Mills, Sander G ; Maccoss, Malcolm ; Sadowski, Sharon ; Cascieri, Margaret A ; Tsao, Kwei-Lan ; Chicchi, Gary G ; Egger, Linda A ; Luell, Silvi ; Metzger, Joseph M ; Macintyre, D. Euan ; Rupniak, Nadia M.J ; Williams, Angela R ; Hargreaves, Richard J

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4504-4511 [Peer Reviewed Journal]

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