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Association between urinary type IV collagen level and deterioration of renal function in type 2 diabetic patients without overt proteinuria

Araki, Shin-Ichi ; Haneda, Masakazu ; Koya, Daisuke ; Isshiki, Keiji ; Kume, Shinji ; Sugimoto, Toshiro ; Kawai, Hiromichi ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

Diabetes care, August 2010, Vol.33(8), pp.1805-10 [Peer Reviewed Journal]

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GW501516, a PPARδ Agonist, Ameliorates Tubulointerstitial Inflammation in Proteinuric Kidney Disease via Inhibition of TAK1-NFκB Pathway in Mice (PPARδ Agonist in Proteinuric Kidney Disease)

Yang, Xu ; Kume, Shinji ; Tanaka, Yuki ; Isshiki, Keiji ; Araki, Shin-ichi ; Chin-Kanasaki, Masami ; Sugimoto, Toshiro ; Koya, Daisuke ; Haneda, Masakazu ; Sugaya, Takeshi ; Li, Detian ; Han, Ping ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Maegawa, Hiroshi ; Uzu, Takashi Chatziantoniou, Christos (Editor)

PLoS ONE, 2011, Vol.6(9), p.e25271 [Peer Reviewed Journal]

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Fiber-rich diet with brown rice improves endothelial function in type 2 diabetes mellitus: A randomized controlled trial

Kondo, Keiko ; Morino, Katsutaro ; Nishio, Yoshihiko ; Ishikado, Atsushi ; Arima, Hisatomi ; Nakao, Keiko ; Nakagawa, Fumiyuki ; Nikami, Fumio ; Sekine, Osamu ; Nemoto, Ken-Ichi ; Suwa, Makoto ; Matsumoto, Motonobu ; Miura, Katsuyuki ; Makino, Taketoshi ; Ugi, Satoshi ; Maegawa, Hiroshi

PLoS One, Jun 2017, Vol.12(6), p.e0179869 [Peer Reviewed Journal]

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4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation

Ishikado, Atsushi ; Morino, Katsutaro ; Nishio, Yoshihiko ; Nakagawa, Fumiyuki ; Mukose, Atsushi ; Sono, Yoko ; Yoshioka, Nagisa ; Kondo, Keiko ; Sekine, Osamu ; Yoshizaki, Takeshi ; Ugi, Satoshi ; Uzu, Takashi ; Kawai, Hiromichi ; Makino, Taketoshi ; Okamura, Tomio ; Yamamoto, Masayuki ; Kashiwagi, Atsunori ; Maegawa, Hiroshi Schunck, Wolf-Hagen (editor)

PLoS ONE, 2013, Vol.8(7) [Peer Reviewed Journal]

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Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues

Ugi, Satoshi ; Nishio, Yoshihiko ; Yamamoto, Hiroshi ; Ikeda, Kazuhiro ; Kobayashi, Masaaki ; Tsukada, Shuichi ; Kondo, Motoyuki ; Morino, Katsutaro ; Obata, Toshiyuki ; Yoshizaki, Takeshi ; Uzu, Takashi ; Naitoh, Hiroyuki ; Tani, Toru ; Maeda, Shiro ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Obesity (Silver Spring, Md.), July 2010, Vol.18(7), pp.1277-82 [Peer Reviewed Journal]

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6
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Low blood flow estimates in lower-leg arteries predict cardiovascular events in Japanese patients with type 2 diabetes with normal ankle-brachial indexes

Yoshimura, Toru ; Suzuki, Eiji ; Egawa, Katsuya ; Nishio, Yoshihiko ; Maegawa, Hiroshi ; Morikawa, Shigehiro ; Inubushi, Toshiro ; Hisatomi, Akitaka ; Fujimoto, Kazuma ; Kashiwagi, Atsunori

Diabetes care, August 2006, Vol.29(8), pp.1884-90 [Peer Reviewed Journal]

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7
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Stiffness and impaired blood flow in lower-leg arteries are associated with severity of coronary artery calcification among asymptomatic type 2 diabetic patients

Tsuchiya, Masanobu ; Suzuki, Eiji ; Egawa, Katsuya ; Nishio, Yoshihiko ; Maegawa, Hiroshi ; Inoue, Shinji ; Mitsunami, Kenichi ; Morikawa, Shigehiro ; Inubushi, Toshiro ; Kashiwagi, Atsunori

Diabetes care, October 2004, Vol.27(10), pp.2409-15 [Peer Reviewed Journal]

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Prevalence and major risk factors of reduced flow volume in lower extremities with normal ankle-brachial index in Japanese patients with type 2 diabetes

Suzuki, Eiji ; Egawa, Katsuya ; Nishio, Yoshihiko ; Maegawa, Hiroshi ; Tsuchiya, Masanobu ; Haneda, Masakazu ; Yasuda, Hitoshi ; Morikawa, Shigehiro ; Inubushi, Toshiro ; Kashiwagi, Atsunori

Diabetes care, June 2003, Vol.26(6), pp.1764-9 [Peer Reviewed Journal]

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9
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Increased arterial wall stiffness limits flow volume in the lower extremities in type 2 diabetic patients

Suzuki, Eiji ; Kashwagi, Atsunori ; Nishio, Yoshihiko ; Egawa, Katsuya

Diabetes Care, Dec 2001, Vol.24(12), pp.2107-14 [Peer Reviewed Journal]

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10
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MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3

Yamamoto, Hirotaka ; Morino, Katsutaro ; Nishio, Yoshihiko ; Ugi, Satoshi ; Yoshizaki, Takeshi ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

American Journal of Physiology, Dec 15, 2012, Vol.303(12), p.E1419 [Peer Reviewed Journal]

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11
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Regulation of ATP-sensitive potassium channel subunit Kir6.2 expression in rat intestinal insulin-producing progenitor cells

Hashimoto, Tetsuya ; Nakamura, Takaaki ; Maegawa, Hiroshi ; Nishio, Yoshihiko ; Egawa, Katsuya ; Kashiwagi, Atsunori

The Journal of biological chemistry, 21 January 2005, Vol.280(3), pp.1893-900 [Peer Reviewed Journal]

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12
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Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display

Aiello, Lloyd ; Robinson, Gregory ; Lin, You-Wei ; Nishio, Yoshihiko ; King, George

Proceedings of the National Academy of Sciences of the United States of America, Jun 21, 1994, Vol.91(13), p.6231 [Peer Reviewed Journal]

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13
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Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells

Sekine, Osamu ; Nishio, Yoshihiko ; Egawa, Katsuya ; Nakamura, Takaaki ; Maegawa, Hiroshi ; Kashiwagi, Atsunori

The Journal of biological chemistry, 27 September 2002, Vol.277(39), pp.36631-9 [Peer Reviewed Journal]

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14
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Regulation and role of the mitochondrial transcription factor in the diabetic rat heart

Nishio, Yoshihiko ; Kanazawa, Akio ; Nagai, Yoshio ; Inagaki, Hidetoshi ; Kashiwagi, Atsunori

Annals of the New York Academy of Sciences, April 2004, Vol.1011, pp.78-85 [Peer Reviewed Journal]

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15
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Regulation and Role of the Mitochondrial Transcription Factor in the Diabetic Rat Heart

Nishio, Yoshihiko ; Kanazawa, Akio ; Nagai, Yoshio ; Inagaki, Hidetoshi ; Kashiwagi, Atsunori

Annals of the New York Academy of Sciences, April 2004, Vol.1011(1), pp.78-85 [Peer Reviewed Journal]

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16
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Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes

Kusunoki, Chisato ; Yang, Liu ; Yoshizaki, Takeshi ; Nakagawa, Fumiyuki ; Ishikado, Atsushi ; Kondo, Motoyuki ; Morino, Katsutaro ; Sekine, Osamu ; Ugi, Satoshi ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 04 January 2013, Vol.430(1), pp.225-230 [Peer Reviewed Journal]

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17
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The Combination Therapy of Fenofibrate and Ezetimibe Improved Lipid Profile and Vascular Function Compared with Statins in Patients with Type 2 Diabetes

Shinnakasu, Atsushi ; Yamamoto, Kiyoaki ; Kurano, Mihoko ; Arimura, Hiroshi ; Arimura, Aiko ; Kikuti, Akira ; Hashiguchi, Hiroshi ; Deguchi, Takahisa ; Nishio, Yoshihiko

Journal of atherosclerosis and thrombosis, 01 July 2017, Vol.24(7), pp.735-748 [Peer Reviewed Journal]

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18
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Postprandial activation of protein kinase Cµ regulates the expression of adipocytokines via the transcription factor AP-2β

Kondo, Motoyuki ; Ugi, Satoshi ; Morino, Katsutaro ; Fuke, Tomoya ; Obata, Toshiyuki ; Yoshizaki, Takeshi ; Nishio, Yoshihiko ; Maeda, Shiro ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

International journal of molecular medicine, July 2011, Vol.28(1), pp.95-100 [Peer Reviewed Journal]

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19
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Median neuropathy at the wrist as an early manifestation of diabetic neuropathy

Horinouchi, Shuji ; Deguchi, Takahisa ; Arimura, Kimiyoshi ; Arimura, Aiko ; Dochi, Yukari ; Uto, Tadashi ; Nakamura, Tomonori ; Arimura, Yumiko ; Nishio, Yoshihiko ; Takashima, Hiroshi

Journal of Diabetes Investigation, November 2014, Vol.5(6), pp.709-713 [Peer Reviewed Journal]

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20
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Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: Sub‐analysis of the Japanese Elderly Diabetes Intervention Trial

Araki, Shin‐Ichi ; Nishio, Yoshihiko ; Araki, Atsushi ; Umegaki, Hiroyuki ; Sakurai, Takashi ; Iimuro, Satoshi ; Ohashi, Yasuo ; Uzu, Takashi ; Maegawa, Hiroshi ; Kashiwagi, Atsunori ; Ito, Hideki

Geriatrics & Gerontology International, April 2012, Vol.12, pp.127-133 [Peer Reviewed Journal]

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21
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Intraepidermal nerve fiber density and nerve conduction study parameters correlate with clinical staging of diabetic polyneuropathy

Arimura, Aiko ; Deguchi, Takahisa ; Sugimoto, Kazuhiro ; Uto, Tadashi ; Nakamura, Tomonori ; Arimura, Yumiko ; Arimura, Kimiyoshi ; Yagihashi, Soroku ; Nishio, Yoshihiko ; Takashima, Hiroshi

Diabetes Research and Clinical Practice, January 2013, Vol.99(1), pp.24-29 [Peer Reviewed Journal]

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22
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Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet

Ushio, Masateru ; Nishio, Yoshihiko ; Sekine, Osamu ; Nagai, Yoshio ; Maeno, Yasuhiro ; Ugi, Satoshi ; Yoshizaki, Takeshi ; Morino, Katsutaro ; Kume, Shinji ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

American journal of physiology. Endocrinology and metabolism, 15 July 2013, Vol.305(2), pp.E293-304 [Peer Reviewed Journal]

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23
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Treatable glomerular hyperfiltration in patients with active acromegaly

Fujio, Shingo ; Takano, Koji ; Arimura, Hiroshi ; Habu, Mika ; Bohara, Manoj ; Hirano, Horofumi ; Hanaya, Ryosuke ; Nishio, Yoshihiko ; Koriyama, Chihaya ; Kinoshita, Yasuyuki ; Arita, Kazunori

European journal of endocrinology, October 2016, Vol.175(4), pp.325-33 [Peer Reviewed Journal]

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24
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mRNA expression of platelet activating factor receptor (PAFR) in peripheral blood mononuclear cells is associated with albuminuria and vascular dysfunction in patients with type 2 diabetes

Kurano, Mihoko ; Darestani, Sahar Ghavidel ; Shinnakasu, Atsushi ; Yamamoto, Kiyoaki ; Dochi, Yukari ; Uemura, Kayo ; Ikeda, Yuko ; Kikuchi, Akira ; Hashiguchi, Hiroshi ; Deguchi, Takahisa ; Nishio, Yoshihiko

Diabetes Research and Clinical Practice, February 2018, Vol.136, pp.124-133 [Peer Reviewed Journal]

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25
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Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring

Ugi, Satoshi ; Maegawa, Hiroshi ; Morino, Katsutaro ; Nishio, Yoshihiko ; Sato, Toshiyuki ; Okada, Seiki ; Kikkawa, Yasuo ; Watanabe, Toshihiro ; Nakajima, Hiromu ; Kashiwagi, Atsunori

Diabetes & metabolism journal, August 2016, Vol.40(4), pp.326-33 [Peer Reviewed Journal]

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26
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Autophagy regulates inflammation in adipocytes

Yoshizaki, Takeshi ; Kusunoki, Chisato ; Kondo, Motoyuki ; Yasuda, Mako ; Kume, Shinji ; Morino, Katsutaro ; Sekine, Osamu ; Ugi, Satoshi ; Uzu, Takashi ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 06 January 2012, Vol.417(1), pp.352-357 [Peer Reviewed Journal]

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27
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MR Angiography of Lower Extremities Predicts Cardiovascular Events in Diabetic Patients

Yoshimura, Toru ; Suzuki, Eiji ; Egawa, Katsuya ; Nishio, Yoshihiko

Diabetes, Jun 2005, Vol.54, p.A175 [Peer Reviewed Journal]

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28
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PP2A Activation and TRB3 Induction Are the Two Independent Mechanisms of FFA-Induced Insulin Resistance

Ugi, Satoshi ; Maegawa, Hiroshi ; Egawa, Katsuya ; Nishio, Yoshihiko ; Kashiwagi, Atsunori

Diabetes, Jun 2005, Vol.54, p.A336 [Peer Reviewed Journal]

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29
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Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression

Ikeda, Kazuhiro ; Maegawa, Hiroshi ; Ugi, Satoshi ; Tao, Yukari ; Nishio, Yoshihiko ; Tsukada, Shuichi ; Maeda, Shiro ; Kashiwagi, Atsunori

The Journal of biological chemistry, 20 October 2006, Vol.281(42), pp.31245-53 [Peer Reviewed Journal]

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30
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Single nucleotide polymorphism (-468 Gly to A) at the promoter region of SREBP-1c associates with genetic defect of fructose-induced hepatic lipogenesis corrected

Nagata, Ryoko ; Nishio, Yoshihiko ; Sekine, Osamu ; Nagai, Yoshio ; Maeno, Yasuhiro ; Ugi, Satoshi ; Maegawa, Hiroshi ; Kashiwagi, Atsunori

The Journal of biological chemistry, 09 July 2004, Vol.279(28), pp.29031-42 [Peer Reviewed Journal]

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31
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Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells

Ishikado, Atsushi ; Nishio, Yoshihiko ; Morino, Katsutaro ; Ugi, Satoshi ; Kondo, Hajime ; Makino, Taketoshi ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Biochemical and Biophysical Research Communications, 2010, Vol.402(1), pp.99-104 [Peer Reviewed Journal]

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32
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Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats

Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Taki, Hideki ; Shinozaki, Kazuya

Diabetes, Aug 1998, Vol.47(8), pp.1318-25 [Peer Reviewed Journal]

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33
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Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta

Shinozaki, Kazuya ; Kashiwagi, Atsunori ; Nishio, Yoshihiko ; Okamura, Tomio

Diabetes, Dec 1999, Vol.48(12), pp.2437-45 [Peer Reviewed Journal]

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34
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Glycation, oxidative stress, and scavenger activity: Glucose metabolism and radical scavenger dysfunction in endothelial cells

Kashiwagi, Atunori ; Asahina, Takayuki ; Nishio, Yoshihiko ; Ikebuchi, Motoyoshi

Diabetes, Jul 1996, Vol.45, pp.S84-6 [Peer Reviewed Journal]

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35
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Pyruvate improves deleterious effects of high glucose on activation of pentose phosphate pathway and glutathione redox cycle in endothelial cells

Kashiwagi, Atsunori ; Nishio, Yoshihiko ; Asahina, Takayuki ; Ikebuchi, Motoyoshi

Diabetes, Dec 1997, Vol.46(12), pp.2088-95 [Peer Reviewed Journal]

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36
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Biochemical and molecular mechanisms in the development of diabetic vascular complications

King, George ; Kunisaki, Makoto ; Nishio, Yoshihiko ; Inoguchi, Toyoshi

Diabetes, Jul 1996, Vol.45, pp.S105-8 [Peer Reviewed Journal]

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