skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Index

Results 1 - 50 of 75  for Everything (Includes Articles)

Results 1 2 next page
Show only
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Material Type:
Article
Add to e-Shelf

Catalytic asymmetric hydrogenation to access spiroindane dimethyl acetic acid

He, Shuwen ; Shultz, C. Scott ; Lai, Zhong ; Eid, Ronsar ; Dobbelaar, Peter H ; Ye, Zhixiong ; Nargund, Ravi P

Tetrahedron Letters, 13 July 2011, Vol.52(28), pp.3621-3624 [Peer Reviewed Journal]

Full text available

View all versions
2
Material Type:
Article
Add to e-Shelf

Late-stage lipidation of fully elaborated tryptophan-containing peptides for improved pharmacokinetics

Huang, Chunhui ; Wille, Cannon B ; He, Huaibing ; Reddy, Vijay Bhasker Gangula ; Nargund, Ravi P ; Lin, Songnian ; Palani, Anandan

Tetrahedron Letters, 22 March 2017, Vol.58(12), pp.1219-1222 [Peer Reviewed Journal]

Full text available

View all versions
3
Material Type:
Article
Add to e-Shelf

Synthesis of β-carbolines from aldehydes and ketones via the α-siloxy α,β-unsaturated esters

He, Shuwen ; Lai, Zhong ; Yang, David X ; Hong, Qingmei ; Reibarkh, Mikhail ; Nargund, Ravi P ; Hagmann, William K

Tetrahedron Letters, 2010, Vol.51(33), pp.4361-4364 [Peer Reviewed Journal]

Full text available

View all versions
4
Material Type:
Article
Add to e-Shelf

Facile functionalization at the C2 position of a highly substituted benzofuran

He, Shuwen ; Li, Peng ; Dai, Xing ; Mccomas, Casey C ; Du, Chunyan ; Wang, Ping ; Lai, Zhong ; Liu, Hong ; Yin, Jingjun ; Bulger, Paul G ; Dang, Qun ; Xiao, Dong ; Zorn, Nicolas ; Peng, Xuanjia ; Nargund, Ravi P ; Palani, Anandan

Tetrahedron Letters, 02 April 2014, Vol.55(14), pp.2212-2216 [Peer Reviewed Journal]

Full text available

View all versions
5
Material Type:
Article
Add to e-Shelf

A general approach to access 5,6-dihydroindolo-naphthyridine ring system

He, Shuwen ; Li, Peng ; Dai, Xing ; Liu, Hong ; Lai, Zhong ; Xiao, Dong ; Mccomas, Casey C ; Du, Chunyan ; Liu, Yuehui ; Yin, Jingjun ; Dang, Qun ; Zorn, Nicolas ; Peng, Xuanjia ; Nargund, Ravi P ; Palani, Anandan

Tetrahedron Letters, 05 April 2017, Vol.58(14), pp.1373-1375 [Peer Reviewed Journal]

Full text available

View all versions
6
Material Type:
Article
Add to e-Shelf

A general approach to substituted 6H-pyrido[2′,3′:5,6] [1,3]oxazino[3,4-a]indole via cyclization from an indoline precursor followed by re-aromatization

He, Shuwen ; Li, Peng ; Dai, Xing ; Mccomas, Casey C ; Huang, Hongling ; Zhan, Chaoliang ; Chang, Liang ; Liu, Yuehui ; Chen, Shaojun ; Lai, Zhong ; Liu, Hong ; Yin, Jingjun ; Dang, Qun ; Xiao, Dong ; Zorn, Nicolas ; Peng, Xuanjia ; Nargund, Ravi P ; Palani, Anandan

Tetrahedron Letters, 17 July 2013, Vol.54(29), pp.3755-3758 [Peer Reviewed Journal]

Full text available

View all versions
7
Material Type:
Article
Add to e-Shelf

Preparation of 3,4-fused -spiro[furan-5(5 H),4′-piperidin]-2-one

Liu, Jian ; Jian, Tianying ; Guo, Liangqin ; Atanasova, Tzvetomira ; Nargund, Ravi P

Tetrahedron Letters, 2009, Vol.50(37), pp.5228-5230 [Peer Reviewed Journal]

Full text available

View all versions
8
Material Type:
Article
Add to e-Shelf

Melanocortin-4 receptor (MC4R) agonists for the treatment of obesity

Nargund, Ravi P ; Strack, Alison M ; Fong, Tung M

Journal of medicinal chemistry, 13 July 2006, Vol.49(14), pp.4035-43 [Peer Reviewed Journal]

Full text available

View all versions
9
Stereocontrolled Synthesis of (±)-12a-Deoxytetracycline
Material Type:
Article
Add to e-Shelf

Stereocontrolled Synthesis of (±)-12a-Deoxytetracycline

Stork, Gilbert ; La Clair, James J. ; Spargo, Peter ; Nargund, Ravi P. ; Totah, Nancy

Journal of the American Chemical Society, 01/1996, Vol.118(22), pp.5304-5305 [Peer Reviewed Journal]

Full text available

10
Material Type:
Article
Add to e-Shelf

The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization

Chobanian, Harry R ; Guo, Yan ; Liu, Ping ; Lanza, Thomas J ; Chioda, Marc ; Chang, Linda ; Kelly, Theresa M ; Kan, Yanqing ; Palyha, Oksana ; Guan, Xiao-Ming ; Marsh, Donald J ; Metzger, Joseph M ; Raustad, Katie ; Wang, Sheng-Ping ; Strack, Alison M ; Gorski, Judith N ; Miller, Randy ; Pang, Jianmei ; Lyons, Kathy ; Dragovic, Jasminka ; Ning, Jian G ; Schafer, Wes A ; Welch, Christopher J ; Gong, Xiaoyi ; Gao, Ying-Duo ; Hornak, Viktor ; Reitman, Marc L ; Nargund, Ravi P ; Lin, Linus S

Bioorganic & Medicinal Chemistry, 01 May 2012, Vol.20(9), pp.2845-2849 [Peer Reviewed Journal]

Full text available

View all versions
11
Material Type:
Article
Add to e-Shelf

Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase

Liu, Hong ; Dai, Xing ; He, Shuwen ; Brockunier, Linda ; Marcantonio, Karen ; Ludmerer, Steven W ; Li, Fangbiao ; Feng, Kung-I ; Nargund, Ravi P ; Palani, Anandan

Bioorganic & Medicinal Chemistry Letters [Peer Reviewed Journal]

Full text available

View all versions
12
Material Type:
Article
Add to e-Shelf

Synthetic studies on diterpenes from a termite soldier: Total synthesis of (±)-biflora-4,10(19),15-triene

Grieco, Paul A ; Nargund, Ravi P

Tetrahedron Letters, 1986, Vol.27(40), pp.4813-4816 [Peer Reviewed Journal]

Full text available

View all versions
13
Material Type:
Article
Add to e-Shelf

Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists

Lai, Zhong ; He, Shuwen ; Sherer, Edward C ; Wu, Zhicai ; Yu, Yang ; Ball, Richard ; Hong, Qingmei ; Yang, David X ; Guo, Liangqing ; Li, Derun ; Tuang, Quang ; Chicchi, Gary G ; Trusca, Dorina ; Tsao, Kwei-Lan ; Zhou, Yun-Ping ; Howard, Andrew D ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 01 September 2015, Vol.25(17), pp.3520-3525 [Peer Reviewed Journal]

Full text available

View all versions
14
Material Type:
Article
Add to e-Shelf

Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists

Lo, Michael M.-C ; Chobanian, Harry R ; Palyha, Oksana ; Kan, Yanqing ; Kelly, Theresa M ; Guan, Xiao-Ming ; Reitman, Marc L ; Dragovic, Jasminka ; Lyons, Kathryn A ; Nargund, Ravi P ; Lin, Linus S

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(7), pp.2040-2043 [Peer Reviewed Journal]

Full text available

View all versions
15
Material Type:
Article
Add to e-Shelf

Chemical transformations in the quassinoid series: Construction of the sensitive hydroxy enone functionality present in the ring A of quassimarin and related quassinoids

Spohn, Ronald F ; Grieco, Paul A ; Nargund, Ravi P

Tetrahedron Letters, 1987, Vol.28(22), pp.2491-2494 [Peer Reviewed Journal]

Full text available

View all versions
16
Peptidomimetic Growth Hormone Secretagogues. Design Considerations and Therapeutic Potential
Material Type:
Article
Add to e-Shelf

Peptidomimetic Growth Hormone Secretagogues. Design Considerations and Therapeutic Potential

Nargund, Ravi P. ; Patchett, Arthur A. ; Bach, Mark A. ; Murphy, M. Gail ; Smith, Roy G.

Journal of Medicinal Chemistry, 08/1998, Vol.41(17), pp.3103-3127 [Peer Reviewed Journal]

Full text available

View all versions
17
Material Type:
Article
Add to e-Shelf

Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonists

Pogozheva, Irina D ; Chai, Biao-Xin ; Lomize, Andrei L ; Fong, Tung M ; Weinberg, David H ; Nargund, Ravi P ; Mulholland, Michael W ; Gantz, Ira ; Mosberg, Henry I

Biochemistry, 30 August 2005, Vol.44(34), pp.11329-41 [Peer Reviewed Journal]

Full text available

View all versions
18
Material Type:
Article
Add to e-Shelf

Body temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments

Metzger, Joseph M ; Gagen, Karen ; Raustad, Kate A ; Yang, Liming ; White, Amanda ; Wang, Sheng-Ping ; Craw, Stephanie ; Liu, Ping ; Lanza, Thomas ; Lin, Linus S ; Nargund, Ravi P ; Guan, Xiao-Ming ; Strack, Alison M ; Reitman, Marc L

American journal of physiology. Endocrinology and metabolism, November 2010, Vol.299(5), pp.E816-24 [Peer Reviewed Journal]

Full text available

View all versions
19
Material Type:
Article
Add to e-Shelf

Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3 H-pyrazolo[3,4- c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists

Guo, Cheng ; Guzzo, Peter R ; Hadden, Mark ; Sargent, Bruce J ; Yet, Larry ; Kan, Yanqing ; Palyha, Oksana ; Kelly, Theresa M ; Guan, Xiaoming ; Rosko, Kim ; Gagen, Karen ; Metzger, Joseph M ; Dragovic, Jasminka ; Lyons, Kathryn ; Lin, Linus S ; Nargund, Ravi P

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(9), pp.2785-2789 [Peer Reviewed Journal]

Full text available

View all versions
20
Material Type:
Article
Add to e-Shelf

A role for the melanocortin 4 receptor in sexual function

Van Der Ploeg, Lex H T ; Martin, William J ; Howard, Andrew D ; Nargund, Ravi P ; Austin, Christopher P ; Guan, Xiaoming ; Drisko, Jennifer ; Cashen, Doreen ; Sebhat, Iyassu ; Patchett, Arthur A ; Figueroa, David J ; Dilella, Anthony G ; Connolly, Brett M ; Weinberg, David H ; Tan, Carina P ; Palyha, Oksana C ; Pong, Sheng-Shung ; Macneil, Tanya ; Rosenblum, Charles ; Vongs, Aurawan ; Tang, Rui ; Yu, Hong ; Sailer, Andreas W ; Fong, Tung Ming ; Huang, Cathy ; Tota, Michael R ; Chang, Ray S ; Stearns, Ralph ; Tamvakopoulos, Constantin ; Christ, George ; Drazen, Deborah L ; Spar, Brian D ; Nelson, Randy J ; Macintyre, D Euan

Proceedings of the National Academy of Sciences of the United States of America, 20 August 2002, Vol.99(17), pp.11381-6 [Peer Reviewed Journal]

Full text available

View all versions
21
Material Type:
Article
Add to e-Shelf

Erratum. Engineering Glucose Responsiveness Into Insulin. Diabetes 2018;67:299-308

Kaarsholm, Niels C ; Lin, Songnian ; Yan, Lin ; Kelly, Theresa ; Van Heek, Margaret ; Mu, James ; Wu, Margaret ; Dai, Ge ; Cui, Yan ; Zhu, Yonghua ; Carballo-Jane, Ester ; Reddy, Vijay ; Zafian, Peter ; Huo, Pei ; Shi, Shuai ; Antochshuk, Valentyn ; Ogawa, Aimie ; Liu, Franklin ; Souza, Sandra C ; Seghezzi, Wolfgang ; Duffy, Joseph L ; Erion, Mark ; Nargund, Ravi P ; Kelley, David E

Diabetes, May 2018, Vol.67(5), pp.1030 [Peer Reviewed Journal]

Full text available

View all versions
22
Material Type:
Article
Add to e-Shelf

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

Hong, Qingmei ; Bakshi, Raman K ; Palucki, Brenda L ; Park, Min K ; Ye, Zhixiong ; He, Shuwen ; Pollard, Patrick G ; Sebhat, Iyassu K ; Liu, Jian ; Guo, Liangqin ; Cashen, Doreen E ; Martin, William J ; Weinberg, David H ; Macneil, Tanya ; Tang, Rui ; Tamvakopoulos, Constantin ; Peng, Qianping ; Miller, Randy R ; Stearns, Ralph A ; Chen, Howard Y ; Chen, Airu S ; Strack, Alison M ; Fong, Tung M ; Macintyre, D. Euan ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(8), pp.2330-2334 [Peer Reviewed Journal]

Full text available

View all versions
23
Material Type:
Article
Add to e-Shelf

Discovery of phenyl acetamides as potent and selective GPR119 agonists

Zhu, Cheng ; Wang, Liping ; Zhu, Yuping ; Guo, Zack Zhiqiang ; Liu, Ping ; Hu, Zhiyong ; Szewczyk, Jason W ; Kang, Ling ; Chicchi, Gary ; Ehrhardt, Anka ; Woods, Andrea ; Seo, Toru ; Woods, Morgan ; van Heek, Margaret ; Dingley, Karen H ; Pang, Jianmei ; Salituro, Gino M ; Powell, Joyce ; Terebetski, Jenna L ; Hornak, Viktor ; Campeau, Louis-Charles ; Orr, Robert K ; Ujjainwalla, Feroze ; Miller, Michael ; Stamford, Andrew ; Wood, Harold B ; Kowalski, Timothy ; Nargund, Ravi P ; Edmondson, Scott D

Bioorganic & Medicinal Chemistry Letters, 01 March 2017, Vol.27(5), pp.1124-1128 [Peer Reviewed Journal]

Full text available

View all versions
24
Material Type:
Article
Add to e-Shelf

Antiobesity effect of MK-5046, a novel bombesin receptor subtype-3 agonist

Guan, Xiao-Ming ; Metzger, Joseph M ; Yang, Liming ; Raustad, Kate A ; Wang, Sheng-Ping ; Spann, Stephanie K ; Kosinski, Jennifer A ; Yu, Hong ; Shearman, Lauren P ; Faidley, Terry D ; Palyha, Oksana ; Kan, Yanqing ; Kelly, Theresa M ; Sebhat, Iyassu ; Lin, Linus S ; Dragovic, Jasminka ; Lyons, Kathy A ; Craw, Stephanie ; Nargund, Ravi P ; Marsh, Donald J ; Strack, Alison M ; Reitman, Marc L

The Journal of pharmacology and experimental therapeutics, February 2011, Vol.336(2), pp.356-64 [Peer Reviewed Journal]

Full text available

25
Material Type:
Article
Add to e-Shelf

Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity

Chobanian, Harry R ; Guo, Yan ; Liu, Ping ; Chioda, Marc ; Lanza, Thomas J ; Chang, Linda ; Kelly, Theresa M ; Kan, Yanqing ; Palyha, Oksana ; Guan, Xiao-Ming ; Marsh, Donald J ; Metzger, Joseph M ; Gorski, Judith N ; Raustad, Kate ; Wang, Sheng-Ping ; Strack, Alison M ; Miller, Randy ; Pang, Jianmei ; Madeira, Maria ; Lyons, Kathy ; Dragovic, Jasminka ; Reitman, Marc L ; Nargund, Ravi P ; Lin, Linus S

ACS medicinal chemistry letters, 08 March 2012, Vol.3(3), pp.252-6 [Peer Reviewed Journal]

Full text available

View all versions
26
Material Type:
Article
Add to e-Shelf

Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain l-2-hydroxy acid oxidase

Barawkar, Dinesh A ; Bandyopadhyay, Anish ; Deshpande, Anil ; Koul, Summon ; Kandalkar, Sachin ; Patil, Pradeep ; Khose, Goraksha ; Vyas, Samir ; Mone, Mahesh ; Bhosale, Shubhangi ; Singh, Umesh ; De, Siddhartha ; Meru, Ashwin ; Gundu, Jayasagar ; Chugh, Anita ; Palle, Venkata P ; Mookhtiar, Kasim A ; Vacca, Joseph P ; Chakravarty, Prasun K ; Nargund, Ravi P ; Wright, Samuel D ; Roy, Sophie ; Graziano, Michael P ; Cully, Doris ; Cai, Tian-Quan ; Singh, Sheo B

Bioorganic & Medicinal Chemistry Letters, 01 July 2012, Vol.22(13), pp.4341-4347 [Peer Reviewed Journal]

Full text available

View all versions
27
Material Type:
Article
Add to e-Shelf

Discovery of a potent and selective small molecule hGPR91 antagonist

Bhuniya, Debnath ; Umrani, Dhananjay ; Dave, Bhavesh ; Salunke, Deepak ; Kukreja, Gagan ; Gundu, Jayasagar ; Naykodi, Minakshi ; Shaikh, Nadim S ; Shitole, Prasad ; Kurhade, Santosh ; De, Siddhartha ; Majumdar, Sreemita ; Reddy, Srinivasa B ; Tambe, Suhas ; Shejul, Yogesh ; Chugh, Anita ; Palle, Venkata P ; Mookhtiar, Kasim A ; Cully, Doris ; Vacca, Joseph ; Chakravarty, Prasun K ; Nargund, Ravi P ; Wright, Samuel D ; Graziano, Michael P ; Singh, Sheo B ; Roy, Sophie ; Cai, Tian-Quan

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(12), pp.3596-3602 [Peer Reviewed Journal]

Full text available

View all versions
28
Material Type:
Article
Add to e-Shelf

Engineering Glucose Responsiveness Into Insulin

Kaarsholm, Niels C ; Lin, Songnian ; Yan, Lin ; Kelly, Theresa ; Van Heek, Margaret ; Mu, James ; Wu, Margaret ; Dai, Ge ; Cui, Yan ; Zhu, Yonghua ; Carballo-Jane, Ester ; Reddy, Vijay ; Zafian, Peter ; Huo, Pei ; Shi, Shuai ; Antochshuk, Valentyn ; Ogawa, Aimie ; Liu, Franklin ; Souza, Sandra C ; Seghezzi, Wolfgang ; Duffy, Joseph L ; Erion, Mark ; Nargund, Ravi P ; Kelley, David E

Diabetes, February 2018, Vol.67(2), pp.299-308 [Peer Reviewed Journal]

Full text available

View all versions
29
Material Type:
Article
Add to e-Shelf

Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity

Sebhat, Iyassu K ; Franklin, Christopher ; Lo, Michael M-C ; Chen, David ; Jewell, James P ; Miller, Randy ; Pang, Jianmei ; Palyha, Oksana ; Kan, Yanqing ; Kelly, Theresa M ; Guan, Xiao-Ming ; Marsh, Donald J ; Kosinski, Jennifer A ; Metzger, Joseph M ; Lyons, Kathryn ; Dragovic, Jasminka ; Guzzo, Peter R ; Henderson, Alan J ; Reitman, Marc L ; Nargund, Ravi P ; Wyvratt, Matthew J ; Lin, Linus S

ACS medicinal chemistry letters, 13 January 2011, Vol.2(1), pp.43-7 [Peer Reviewed Journal]

Full text available

View all versions
30
Material Type:
Article
Add to e-Shelf

Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists

Li, Derun ; Wu, Zhicai ; Yu, Yang ; Ball, Richard G ; Guo, Liangqin ; Sherer, Edward ; He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Qi, Hongbo ; Truong, Quang ; Yang, David X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Trujillo, Maria ; Pachanski, Michele ; Eiermann, George J ; Howard, Andrew D ; Zhou, Yun-Ping ; Zhang, Bei B ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 12 June 2014, Vol.5(6), pp.690-5 [Peer Reviewed Journal]

Full text available

View all versions
31
Material Type:
Article
Add to e-Shelf

A glucose-responsive insulin therapy protects animals against hypoglycemia

Yang, Ruojing ; Wu, Margaret ; Lin, Songnian ; Nargund, Ravi P ; Li, Xinghai ; Kelly, Theresa ; Yan, Lin ; Dai, Ge ; Qian, Ying ; Dallas-Yang, Qing ; Fischer, Paul A ; Cui, Yan ; Shen, Xiaolan ; Huo, Pei ; Feng, Danqing Dennis ; Erion, Mark D ; Kelley, David E ; Mu, James

JCI insight, 11 January 2018, Vol.3(1)

Full text available

32
Material Type:
Article
Add to e-Shelf

Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity

Hadden, Mark ; Goodman, Allan ; Guo, Cheng ; Guzzo, Peter R ; Henderson, Alan J ; Pattamana, Kevin ; Ruenz, Megan ; Sargent, Bruce J ; Swenson, Brian ; Yet, Larry ; Liu, Jian ; He, Shuwen ; Sebhat, Iyassu K ; Lin, Linus S ; Tamvakopoulos, Constantin ; Peng, Qianping ; Kan, Yanqing ; Palyha, Oksana ; Kelly, Theresa M ; Guan, Xiao-Ming ; Metzger, Joseph M ; Reitman, Marc L ; Nargund, Ravi P

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(9), pp.2912-2915 [Peer Reviewed Journal]

Full text available

View all versions
33
Material Type:
Article
Add to e-Shelf

Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety

He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Wu, Zhicai ; Yu, Yang ; Kim, David W ; Ting, Pauline C ; Kuethe, Jeffrey T ; Yang, Ginger X ; Jian, Tianying ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto D ; Sperbeck, Donald M ; Sonatore, Lisa M ; Wiltsie, Judyann ; Chung, Christine C ; Gibson, Jack T ; Lisnock, Jeanmarie ; Murphy, Beth A ; Gorski, Judith N ; Liu, Jinqi ; Chen, Dunlu ; Chen, Xiaoli ; Wolff, Michael ; Tong, Sharon X ; Madeira, Maria ; Karanam, Bindhu V ; Shen, Dong-Ming ; Balkovec, James M ; Pinto, Shirly ; Nargund, Ravi P ; Devita, Robert J

ACS medicinal chemistry letters, 08 August 2013, Vol.4(8), pp.773-8 [Peer Reviewed Journal]

Full text available

View all versions
34
Material Type:
Article
Add to e-Shelf

Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality

Liu, Ping ; Lanza, Thomas J ; Chioda, Marc ; Jones, Carrie ; Chobanian, Harry R ; Guo, Yan ; Chang, Linda ; Kelly, Theresa M ; Kan, Yanqing ; Palyha, Oksana ; Guan, Xiao-Ming ; Marsh, Donald J ; Metzger, Joseph M ; Ramsay, Katie ; Wang, Sheng-Ping ; Strack, Alison M ; Miller, Randy ; Pang, Jianmei ; Lyons, Kathy ; Dragovic, Jasminka ; Ning, Jian G ; Schafer, Wes A ; Welch, Christopher J ; Gong, Xiaoyi ; Gao, Ying-Duo ; Hornak, Viktor ; Ball, Richard G ; Tsou, Nancy ; Reitman, Marc L ; Wyvratt, Matthew J ; Nargund, Ravi P ; Lin, Linus S

ACS medicinal chemistry letters, 08 December 2011, Vol.2(12), pp.933-7 [Peer Reviewed Journal]

Full text available

View all versions
35
Material Type:
Article
Add to e-Shelf

Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Lai, Zhong ; Ye, Zhixiong ; Dobbelaar, Peter H ; Shah, Shrenik K ; Truong, Quang ; Du, Wu ; Guo, Liangqin ; Liu, Jian ; Jian, Tianying ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James ; Reibarkh, Mikhail ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 10 July 2014, Vol.5(7), pp.748-53 [Peer Reviewed Journal]

Full text available

View all versions
36
Material Type:
Article
Add to e-Shelf

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Guo, Liangqin ; Parker, Dann L ; Zang, Yi ; Sweis, Ramzi F ; Liu, Weiguo ; Sherer, Edward C ; Buist, Nicole ; Terebetski, Jenna ; Kelly, Terri ; Bugianesi, Randal ; Priest, Birgit T ; Dingley, Karen H ; Li, Xiaofang ; Mitelman, Stan ; Salituro, Gino ; Trujillo, Maria E ; Pachanski, Michele ; Kirkland, Melissa ; Powles, Mary Ann ; Eiermann, George J ; Feng, Yue ; Shang, Jin ; Howard, Andrew D ; Ujjainwalla, Feroze ; Sinz, Christopher J ; Debenham, John S ; Edmondson, Scott D ; Nargund, Ravi P ; Hagmann, William K ; Li, Derun

ACS medicinal chemistry letters, 08 December 2016, Vol.7(12), pp.1107-1111 [Peer Reviewed Journal]

Full text available

View all versions