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1
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Epigenetic disregulation induces cell growth retardation in primary cultured glial cells

Nagai, Kaoru ; Natori, Takamitsu ; Nishino, Toru ; Kodaira, Fumiaki

Journal of Bioscience and Bioengineering, 2008, Vol.105(5), pp.470-475 [Peer Reviewed Journal]

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2
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Total syntheses and endoplasmic reticulum stress suppressive activities of hericenes A−C and their derivatives

Kobayashi, Shoji ; Hamada, Yoshiki ; Yasumoto, Takeshi ; Hashino, Yuuki ; Masuyama, Araki ; Nagai, Kaoru

Tetrahedron Letters, 02 May 2018, Vol.59(18), pp.1733-1736 [Peer Reviewed Journal]

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3
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Thapsigargin-induced ER stress suppressive compounds from the mushroom Mycoleptodonoides aitchisonii

Choi, Jae-Hoon ; Suzuki, Tomohiro ; Okumura, Hiroshi ; Nagai, Kaoru ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Tetrahedron Letters, 07 October 2015, Vol.56(41), pp.5561-5563 [Peer Reviewed Journal]

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4
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Bovine milk phospholipid fraction protects Neuro2a cells from endoplasmic reticulum stress via PKC activation and autophagy

Nagai, Kaoru

Journal of Bioscience and Bioengineering, October 2012, Vol.114(4), pp.466-471 [Peer Reviewed Journal]

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5
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Leccinine A, an endoplasmic reticulum stress-suppressive compound from the edible mushroom Leccinum extremiorientale

Choi, Jae-Hoon ; Ozawa, Nobuhiko ; Yamakawa, Yasuhiro ; Nagai, Kaoru ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Tetrahedron, 2011, Vol.67(35), pp.6649-6653 [Peer Reviewed Journal]

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6
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Bioremediation of the neonicotinoid insecticide clothianidin by the white-rot fungus Phanerochaete sordida

Mori, Toshio ; Wang, Jianqiao ; Tanaka, Yusuke ; Nagai, Kaoru ; Kawagishi, Hirokazu ; Hirai, Hirofumi

Journal of Hazardous Materials, 05 January 2017, Vol.321, pp.586-590 [Peer Reviewed Journal]

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7
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Identification of specificity in Hdac inhibitory activity on neuroprotection from ER stress induced cell death in Neuro2a cells

Nagai, Kaoru ; Tahara, Yuriko

Neuroscience Research, September 2011, Vol.71, pp.e343-e343 [Peer Reviewed Journal]

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8
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Proof of the existence of an unstable amino acid: pleurocybellaziridine in Pleurocybella porrigens

Wakimoto, Toshiyuki ; Asakawa, Tomohiro ; Akahoshi, Saeko ; Suzuki, Tomohiro ; Nagai, Kaoru ; Kawagishi, Hirokazu ; Kan, Toshiyuki

Angewandte Chemie (International ed. in English), 01 February 2011, Vol.50(5), pp.1168-70 [Peer Reviewed Journal]

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9
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Strophasterols A to D with an Unprecedented Steroid Skeleton: From the Mushroom Stropharia rugosoannulata

Wu, Jing ; Tokuyama, Shinji ; Nagai, Kaoru ; Yasuda, Nobuhiro ; Noguchi, Keiichi ; Matsumoto, Tetsuo ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Angewandte Chemie International Edition, 22 October 2012, Vol.51(43), pp.10820-10822 [Peer Reviewed Journal]

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10
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Unusual amino acid derivatives from the mushroom Pleurocybella porrigens

Kawaguchi, Takumi ; Suzuki, Tomohiro ; Kobayashi, Yuka ; Kodani, Shinya ; Hirai, Hirofumi ; Nagai, Kaoru ; Kawagishi, Hirokazu

Tetrahedron, 2010, Vol.66(2), pp.504-507 [Peer Reviewed Journal]

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11
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Termitomycamides A to E, fatty acid amides isolated from the mushroom Termitomyces titanicus, suppress endoplasmic reticulum stress

Choi, Jae-Hoon ; Maeda, Kohei ; Nagai, Kaoru ; Harada, Etsuko ; Kawade, Mitsuo ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Organic letters, 05 November 2010, Vol.12(21), pp.5012-5 [Peer Reviewed Journal]

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12
Soy isoflavone and its metabolite equol induces C6 glioma cell death via estrogen receptor-β and mitochondrial dysfunction
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Soy isoflavone and its metabolite equol induces C6 glioma cell death via estrogen receptor-β and mitochondrial dysfunction

Nagai, Kaoru ; Inagawa, Yuta

Neuroscience Research, 1/2010, Vol.68, S1, p.e429 [Peer Reviewed Journal]

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13
Valproic acid stimulates differentiation of CG4-16 cells via HDAC inhibitory activity
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Valproic acid stimulates differentiation of CG4-16 cells via HDAC inhibitory activity

Inagawa, Yuta ; Nagai, Kaoru

Neuroscience Research, 1/2010, Vol.68, S1, p.e131 [Peer Reviewed Journal]

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14
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The sulfated polysaccharides regulate neuronal plasticity in visual cortex

Natori, Takamitsu ; Komatsu, Yukio ; Nagai, Kaoru ; Kadomatsu, Kenji

Neuroscience Research, September 2011, Vol.71, pp.e256-e256 [Peer Reviewed Journal]

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15
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Sodium valproate induced cellular senescence in neuronal precursor cell lines MEB5 and CG4-16

Marubashi, Takuto ; Inagawa, Yuta ; Nagai, Kaoru

Neuroscience Research, September 2011, Vol.71, pp.e122-e123 [Peer Reviewed Journal]

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16
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Histone deacetylase inhibitory effect of B razilian propolis and its association with the antitumor effect in Neuro2a cells

Ishiai, Shinobu ; Tahara, Wataru ; Yamamoto, Etsuko ; Yamamoto, Rindai ; Nagai, Kaoru

Food Science & Nutrition, September 2014, Vol.2(5), pp.565-570 [Peer Reviewed Journal]

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17
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StrophasterolsA to D with an Unprecedented Steroid Skeleton: From the Mushroom Stropharia rugosoannulata

Wu, Jing ; Tokuyama, Shinji ; Nagai, Kaoru ; Yasuda, Nobuhiro ; Noguchi, Keiichi ; Matsumoto, Tetsuo ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Angewandte Chemie, Oct 22, 2012, Vol.124(43), pp.10978-10980 [Peer Reviewed Journal]

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18
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Strophasterols A to D with an Unprecedented Steroid Skeleton: From the Mushroom Stropharia rugosoannulata

Wu, Jing ; Tokuyama, Shinji ; Nagai, Kaoru ; Yasuda, Nobuhiro ; Noguchi, Keiichi ; Matsumoto, Tetsuo ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Angewandte Chemie, 22 October 2012, Vol.124(43), pp.10978-10980 [Peer Reviewed Journal]

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19
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Proof of the Existence of an Unstable Amino Acid: Pleurocybellaziridine in Pleurocybella porrigens

Wakimoto, Toshiyuki ; Asakawa, Tomohiro ; Akahoshi, Saeko ; Suzuki, Tomohiro ; Nagai, Kaoru ; Kawagishi, Hirokazu ; Kan, Toshiyuki

Angewandte Chemie, Feb 1, 2011, Vol.123(5), pp.1200-1202 [Peer Reviewed Journal]

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20
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Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta

Suzuki, Tomohiro ; Choi, Jae-Hoon ; Kawaguchi, Takumi ; Yamashita, Kimiko ; Morita, Akio ; Hirai, Hirofumi ; Nagai, Kaoru ; Hirose, Tomoyasu ; Ōmura, Satoshi ; Sunazuka, Toshiaki ; Kawagishi, Hirokazu

Bioorganic & Medicinal Chemistry Letters, 01 July 2012, Vol.22(13), pp.4246-4248 [Peer Reviewed Journal]

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21
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Selective, potent blockade of the IRE 1 and ATF 6 pathways by 4‐phenylbutyric acid analogues

Zhang, Hui ; Nakajima, Shotaro ; Kato, Hironori ; Gu, Liubao ; Yoshitomi, Tatsuya ; Nagai, Kaoru ; Shinmori, Hideyuki ; Kokubo, Susumu ; Kitamura, Masanori

British Journal of Pharmacology, October 2013, Vol.170(4), pp.822-834 [Peer Reviewed Journal]

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22
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Cordyceps militaris improves the survival of Dahl salt-sensitive hypertensive rats possibly via influences of mitochondria and autophagy functions

Takakura, Kentaro ; Ito, Shogo ; Sonoda, Junya ; Tabata, Koji ; Shiozaki, Motoko ; Nagai, Kaoru ; Shibata, Masahiro ; Koike, Masato ; Uchiyama, Yasuo ; Gotow, Takahiro

Heliyon, November 2017, Vol.3(11), p.e00462 [Peer Reviewed Journal]

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23
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Endoplasmic reticulum stress suppressive compounds from the edible mushroom Mycoleptodonoides aitchisonii

Choi, Jae-Hoon ; Suzuki, Tomohiro ; Okumura, Hiroshi ; Noguchi, Keiichi ; Kondo, Mitsuru ; Nagai, Kaoru ; Hirai, Hirofumi ; Kawagishi, Hirokazu

Journal of natural products, 25 July 2014, Vol.77(7), pp.1729-33 [Peer Reviewed Journal]

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24
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Endoplasmic reticulum (ER) stress protecting compounds from the mushroom Mycoleptodonoides aitchisonii

Choi, Jae-Hoon ; Horikawa, Madoka ; Okumura, Hiroshi ; Kodani, Shinya ; Nagai, Kaoru ; Hashizume, Daisuke ; Koshino, Hiroyuki ; Kawagishi, Hirokazu

Tetrahedron, 2009, Vol.65(1), pp.221-224 [Peer Reviewed Journal]

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25
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Induction of apoptotic cell death preferentially in reactive astrocytes by concanavalin A

Yoshida, Hideki ; Nagai, Kaoru

Journal of Bioscience and Bioengineering, 2009, Vol.108(3), pp.248-251 [Peer Reviewed Journal]

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26
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Inhibition of α-mannosidase attenuates endoplasmic reticulum stress-induced neuronal cell death

Miyake, Kunio ; Nagai, Kaoru

Neurotoxicology, 2009, Vol.30(1), pp.144-150 [Peer Reviewed Journal]

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27
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An endoplasmic reticulum (ER) stress-suppressive compound and its analogues from the mushroom Hericium erinaceum

Ueda, Keiko ; Tsujimori, Megumi ; Kodani, Shinya ; Chiba, Akiko ; Kubo, Masakazu ; Masuno, Kazuhiko ; Sekiya, Atsushi ; Nagai, Kaoru ; Kawagishi, Hirokazu

Bioorganic & Medicinal Chemistry, 2008, Vol.16(21), pp.9467-9470 [Peer Reviewed Journal]

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28
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Tunicamycin inhibits NMDA and AMPA receptor responses independently of N-glycosylation

Maruo, Keishi ; Nagata, Tetsu ; Yamamoto, Satoshi ; Nagai, Kaoru ; Yajima, Yukio ; Maruo, Soji ; Nishizaki, Tomoyuki

Brain Research, 2003, Vol.977(2), pp.294-297 [Peer Reviewed Journal]

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29
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The protective action of nefiracetam against electrophysiological and metabolic damage in the hippocampus after deprivation of glucose and oxygen

Aihara, Hideo ; Li, Xiuxia ; Fujiwara, Susumu ; Matsumura, Takuro ; Okumura, Satoko ; Tozaki, Hidetoshi ; Kanno, Takeshi ; Ohta, Kohei ; Nagai, Kaoru ; Nishizaki, Tomoyuki

Brain Research, 2001, Vol.922(1), pp.158-162 [Peer Reviewed Journal]

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30
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Arachidonic acid peroxides induce apoptotic Neuro-2A cell death in association with intracellular Ca 2+ rise and mitochondrial damage independently of caspase-3 activation

Saitoh, Masaru ; Nagai, Kaoru ; Yaguchi, Takahiro ; Fujikawa, Yoshiko ; Ikejiri, Keiko ; Yamamoto, Satoshi ; Nakagawa, Kazuhiko ; Yamamura, Takehira ; Nishizaki, Tomoyuki

Brain Research, 2003, Vol.991(1), pp.187-194 [Peer Reviewed Journal]

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31
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(−)-Epigallocatechin gallate protects against NO stress-induced neuronal damage after ischemia by acting as an anti-oxidant

Nagai, Kaoru ; Jiang, Min Hai ; Hada, Junichi ; Nagata, Tetsu ; Yajima, Yukio ; Yamamoto, Satoshi ; Nishizaki, Tomoyuki

Brain Research, 2002, Vol.956(2), pp.319-322 [Peer Reviewed Journal]

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32
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Phosphorylation of methyl-CpG binding protein 2 (MeCP2) regulates the intracellular localization during neuronal cell differentiation

Miyake, Kunio ; Nagai, Kaoru

Neurochemistry International, 2007, Vol.50(1), pp.264-270 [Peer Reviewed Journal]

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33
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Interleukin-2 induced Jak-dependent cell death in C6 glioma cells via lectin activity

Inagawa, Yuta ; Kubota, Takeo ; Nagai, Kaoru

Neuroscience Research, 2009, Vol.65, pp.S126-S126 [Peer Reviewed Journal]

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34
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Adenosine triphosphate accelerates recovery from hypoxic/hypoglycemic perturbation of guinea pig hippocampal neurotransmission via a P 2 receptor

Aihara, Hideo ; Fujiwara, Susumu ; Mizuta, Ikuko ; Tada, Hitoshi ; Kanno, Takeshi ; Tozaki, Hidetoshi ; Nagai, Kaoru ; Yajima, Yukio ; Inoue, Kazuhide ; Kondoh, Takeshi ; Motooka, Yasuhiko ; Nishizaki, Tomoyuki

Brain Research, 2002, Vol.952(1), pp.31-37 [Peer Reviewed Journal]

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35
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P1-m20 Jak signaling contributes to Concanavalin A induced C6 glioma cell death

Nagai, Kaoru ; Yoshida, Hideki ; Inagawa, Yuta ; Kubota, Takeo

Neuroscience Research, 2009, Vol.65, pp.S126-S126 [Peer Reviewed Journal]

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36
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