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Pd-catalyzed direct arylation of tautomerizable heterocycles with aryl boronic acids via C-OH bond activation using phosphonium salts

Kang, Fu-An ; Sui, Zhihua ; Murray, William V

Journal of the American Chemical Society, 27 August 2008, Vol.130(34), pp.11300-2 [Peer Reviewed Journal]

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A facile synthesis of 2-(3-alkynyl-2,3-dihydrobenzofuran-3-yl)acetate

Song, Fengbin ; Gaul, Michael D ; Murray, William V

Tetrahedron Letters, 30 September 2015, Vol.56(40), pp.5413-5415 [Peer Reviewed Journal]

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Synthesis of β-Substituted Cyclic Enones via Phosphonium Salt-Activated, Palladium-Catalyzed Cross-Coupling of Cyclic 1,3-Diones

Yang, Shyh-Ming ; Kuo, Gee-Hong ; Gaul, Michael D ; Murray, William V

The Journal of organic chemistry, 15 April 2016, Vol.81(8), pp.3464-9 [Peer Reviewed Journal]

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Microwave assisted ring-opening of epoxides with N-biaryl sulfonamides in the synthesis of matrix metalloproteinase-9 inhibitors

Yang, Shyh-Ming ; Murray, William V

Tetrahedron Letters, 2008, Vol.49(5), pp.835-839 [Peer Reviewed Journal]

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5
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Cross-metathesis assisted by microwave irradiation

Bargiggia, Frédéric C ; Murray, William V

The Journal of organic chemistry, 11 November 2005, Vol.70(23), pp.9636-9 [Peer Reviewed Journal]

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6
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Microwave enabled external carboxymethyl substituents in the ring-closing metathesis

Yang, Cangming ; Murray, William V ; Wilson, Lawrence J

Tetrahedron Letters, 2003, Vol.44(9), pp.1783-1786 [Peer Reviewed Journal]

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Microwave enabled external carboxymethyl substituents in the ring-closing metathesis
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Microwave enabled external carboxymethyl substituents in the ring-closing metathesis

Yang, Cangming ; Murray, William V. ; Wilson, Lawrence J.

Tetrahedron Letters, 2/2003, Vol.44(9), pp.1783-1786 [Peer Reviewed Journal]

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Interesting behavior of alpha,beta-unsaturated oximes in intramolecular 4 + 2 cycloaddition reactions

François, David ; Maden, Amy ; Murray, William V

Organic letters, 10 June 2004, Vol.6(12), pp.1931-4 [Peer Reviewed Journal]

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9
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Solid phase synthesis of highly substituted 2,4-dioxopiperidines

Chai, Wenying ; Murray, William V

Tetrahedron Letters, 1999, Vol.40(40), pp.7185-7188 [Peer Reviewed Journal]

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10
Solid Phase Diels−Alder Reactions of Amino Acid Derived Trienes
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Solid Phase Diels−Alder Reactions of Amino Acid Derived Trienes

Sun, Sengen ; Murray, William V.

The Journal of Organic Chemistry, 08/1999, Vol.64(16), pp.5941-5945 [Peer Reviewed Journal]

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11
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Phosphonium Coupling in the Direct Bond Formations of Tautomerizable Heterocycles via C–OH Bond Activation (Eur. J. Org. Chem. 4/2009

Kang, Fu‐An ; Sui, Zhihua ; Murray, William V.

European Journal of Organic Chemistry, February 2009, Vol.2009(4), pp.451-451 [Peer Reviewed Journal]

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12
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Synthesis of densely functionalized pyrrolidinone templates by an intramolecular oxo-Diels–Alder reaction

Murray, William V ; Mishra, Pranab K ; Sun, Sengen ; Maden, Amy

Tetrahedron Letters, 2002, Vol.43(41), pp.7389-7392 [Peer Reviewed Journal]

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13
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Novel cycloalkene indole carbazole alkaloids via the ring closing metathesis reaction

Wilson, Lawrence J ; Yang, Cangming ; Murray, William V

Tetrahedron Letters, 2007, Vol.48(41), pp.7399-7403 [Peer Reviewed Journal]

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14
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The Synthesis of 3-[3-(4-chlorophenyl)-1-(4-methoxyphenyl) -5-pyrazolyl]-N-hydroxy-N-methylpropanamide a regioisomer of tepoxalin

Murray, William V

Tetrahedron Letters, 1993, Vol.34(12), pp.1863-1866 [Peer Reviewed Journal]

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15
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An azomethine ylide approach to complex alkaloid-like heterocycles

Murray, William V ; Francois, David ; Maden, Amy ; Turchi, Ignatius

The Journal of organic chemistry, 13 April 2007, Vol.72(8), pp.3097-9 [Peer Reviewed Journal]

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16
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A concise synthesis of 7-chloro-2-methylsulfanyl-thiazolo[4,5- b]pyridine-6-carbonitrile, a versatile intermediate for substituted 6-cyanothiazolopyridines

Johnson, Sigmond G ; Connolly, Peter J ; Murray, William V

Tetrahedron Letters, 2006, Vol.47(28), pp.4853-4856 [Peer Reviewed Journal]

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17
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Facile synthesis of α,α′ disubstituted N-hydroxypyrrolidines and N-hydroxypiperidines via double 1,4-addition of hydroxylamine

Bargiggia, Frédéric C ; Murray, William V

Tetrahedron Letters, 2006, Vol.47(19), pp.3191-3193 [Peer Reviewed Journal]

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18
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Amino acid derived intramolecular 1,3-dipolar cycloadditions that form bridged medium ring systems with diastereoselective control

Liu, Yanbin ; Maden, Amy ; Murray, William V

Tetrahedron, 2002, Vol.58(16), pp.3159-3170 [Peer Reviewed Journal]

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19
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An efficient and scalable synthesis of (2 R ,α S )‐3,4‐dihydro‐2‐[3‐(1,1,2,2‐tetrafluoroethoxy)phenyl]‐5‐[3‐(trifluoromethoxy)phenyl]‐α‐(trifluoromethyl)‐1(2 H )‐quinolineethanol: A potent CETP inhibitor

Wang, Aihua ; Zhang, Yan ; Lu, Songfeng ; Murray, William V. ; Kuo, Gee‐Hong

Journal of Heterocyclic Chemistry, November 2010, Vol.47(6), pp.1406-1410 [Peer Reviewed Journal]

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20
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Efficient conversion of Biginelli 3,4-dihydropyrimidin-2(1H)-one to pyrimidines via PyBroP-mediated coupling

Kang, Fu-An ; Kodah, Jason ; Guan, Qunying ; Li, Xiaobing ; Murray, William V

The Journal of organic chemistry, 04 March 2005, Vol.70(5), pp.1957-60 [Peer Reviewed Journal]

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21
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2,5-Diketopiperazines, new chiral auxiliaries for asymmetric Diels-Alder reactions

Le, Thuy X.H ; Bussolari, Jacqueline C ; Murray, William V

Tetrahedron Letters, 1997, Vol.38(22), pp.3849-3852 [Peer Reviewed Journal]

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22
Solid Phase Synthesis of 3,4-Disubstituted-7-carbamoyl-1,2,3,4-tetrahydroquinoxalin-2-ones
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Solid Phase Synthesis of 3,4-Disubstituted-7-carbamoyl-1,2,3,4-tetrahydroquinoxalin-2-ones

Lee, Jung ; Murray, William V. ; Rivero, Ralph A.

The Journal of Organic Chemistry, 06/1997, Vol.62(12), pp.3874-3879 [Peer Reviewed Journal]

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23
Solid-Phase Suzuki Coupling for C−C Bond Formation
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Solid-Phase Suzuki Coupling for C−C Bond Formation

Guiles, Joseph W. ; Johnson, Sigmond G. ; Murray, William V.

The Journal of Organic Chemistry, 01/1996, Vol.61(15), pp.5169-5171 [Peer Reviewed Journal]

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24
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Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists

Zhang, Xuqing ; Sui, Zhihua ; Kauffman, Jack ; Hou, Cuifen ; Chen, Cailin ; Du, Fuyong ; Kirchner, Thomas ; Liang, Yin ; Johnson, Dana ; Murray, William V ; Demarest, Keith

Bioorganic & Medicinal Chemistry Letters, 15 April 2017, Vol.27(8), pp.1760-1764 [Peer Reviewed Journal]

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25
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Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy

Wilson, Lawrence J ; Wang, Bingbing ; Yang, Shyh-Ming ; Scannevin, Robert H ; Burke, Sharon L ; Karnachi, Prabha ; Rhodes, Kenneth J ; Murray, William V

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(21), pp.6485-6490 [Peer Reviewed Journal]

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26
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The synthesis of (9 S)-9-alkyl-9-hydroxyerythromycin A derivatives and their ketolides

Grant, Eugene B ; Weiss, Jesse M ; Branum, Shawn ; Hayden, Stuart ; Johnson, Sigmond ; Guiadeen, Deodialsingh ; Murray, William V ; Macielag, Mark J

Tetrahedron Letters, 2005, Vol.46(16), pp.2731-2735 [Peer Reviewed Journal]

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27
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Solid-phase synthesis of Nα-benzyl- Nα-cinnamyl lysine and glutamic acid derivatives

Connolly, Peter J ; Beers, Kimberly N ; Wetter, Steven K ; Murray, William V

Tetrahedron Letters, 2000, Vol.41(27), pp.5187-5191 [Peer Reviewed Journal]

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28
Vinyl Benzenes as Dienes in Mild Solid-Phase Diels−Alder Reactions †
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Vinyl Benzenes as Dienes in Mild Solid-Phase Diels−Alder Reactions †

Sun, Sengen ; Turchi, Ignatius J. ; Xu, Dawei ; Murray, William V.

The Journal of Organic Chemistry, 04/2000, Vol.65(8), pp.2555-2559 [Peer Reviewed Journal]

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29
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Synthesis and discovery of 2,3-dihydro-3,8-diphenylbenzo[1,4]oxazines as a novel class of potent cholesteryl ester transfer protein inhibitors

Wang, Aihua ; Prouty, Catherine P ; Pelton, Patricia D ; Yong, Maria ; Demarest, Keith T ; Murray, William V ; Kuo, Gee-Hong

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(4), pp.1432-1435 [Peer Reviewed Journal]

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30
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Design, synthesis, and biological evaluation of (2R,alphaS)-3,4-dihydro-2-3-(1,1,2,2-tetrafluoroethoxy)phenyl-5-3-(trifluoromethoxy)-phenyl-alpha-(trifluoromethyl)-1(2H)-quinolineethanol as potent and orally active cholesteryl ester transfer protein inhibitor

Kuo, Gee-Hong ; Rano, Thomas ; Pelton, Patricia ; Demarest, Keith T ; Gibbs, Alan C ; Murray, William V ; Damiano, Bruce P ; Connelly, Margery A

Journal of medicinal chemistry, 26 March 2009, Vol.52(6), pp.1768-72 [Peer Reviewed Journal]

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31
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An intramolecular oxo Diels–Alder approach to 1-oxo-1,2,3,3a,4,7a-hexahydro-pyrano[3,4- c]pyrrole-4-carboxylic acid ethyl esters

Murray, William V ; Mishra, Pranab K ; Turchi, Ignatius J ; Sawicka, Dorota ; Maden, Amy ; Sun, Sengen

Tetrahedron, 2003, Vol.59(45), pp.8955-8961 [Peer Reviewed Journal]

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32
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The mechanism of formation of 6-Aryl-4,6-dioxohexanoic acids from arylketones and succinic anhydride

Murray, William V ; Lalan, Praful ; Connolly, Peter J

Tetrahedron Letters, 1993, Vol.34(33), pp.5189-5192 [Peer Reviewed Journal]

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33
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4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: Urea-based analogs

Yang, Shyh-Ming ; Tang, Yuting ; Zhang, Rui ; Lu, Huajun ; Kuo, Gee-Hong ; Gaul, Michael D ; Li, Yaxin ; Ho, George ; Conway, James G ; Liang, Yin ; Lenhard, James M ; Demarest, Keith T ; Murray, William V

Bioorganic & Medicinal Chemistry Letters, 15 December 2013, Vol.23(24), pp.6773-6776 [Peer Reviewed Journal]

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34
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4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs

Yang, Shyh-Ming ; Tang, Yuting ; Rano, Thomas ; Lu, Huajun ; Kuo, Gee-Hong ; Gaul, Michael D ; Li, Yaxin ; Ho, George ; Lang, Wensheng ; Conway, James G ; Liang, Yin ; Lenhard, James M ; Demarest, Keith T ; Murray, William V

Bioorganic & Medicinal Chemistry Letters, 01 March 2014, Vol.24(5), pp.1437-1441 [Peer Reviewed Journal]

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35
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Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes

Zhang, Xuqing ; Wall, Mark ; Sui, Zhihua ; Kauffman, Jack ; Hou, Cuifen ; Chen, Cailin ; Du, Fuyong ; Kirchner, Thomas ; Liang, Yin ; Johnson, Dana L ; Murray, William V ; Demarest, Keith

ACS medicinal chemistry letters, 11 May 2017, Vol.8(5), pp.560-565 [Peer Reviewed Journal]

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36
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Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes

Zhang, Xuqing ; Cai, Chaozhong ; Sui, Zhihua ; Macielag, Mark ; Wang, Yuanping ; Yan, Wen ; Suckow, Arthur ; Hua, Hong ; Bell, Austin ; Haug, Peter ; Clapper, Wilma ; Jenkinson, Celia ; Gunnet, Joseph ; Leonard, James ; Murray, William V

ACS medicinal chemistry letters, 14 September 2017, Vol.8(9), pp.947-952 [Peer Reviewed Journal]

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