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Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in

Uyehara, Christopher M ; Mckay, Daniel J

Proceedings of the National Academy of Sciences of the United States of America, 14 May 2019, Vol.116(20), pp.9893-9902 [Peer Reviewed Journal]

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Defining Components of the ßcatenin Destruction Complex and Exploring Its Regulation and Mechanisms of Action during Development (The ßcatenin Destruction Complex)

Roberts, David M ; Pronobis, Mira I ; Alexandre, Kelly M ; Rogers, Gregory C ; Poulton, John S ; Schneider, Daniel E ; Jung, Kuo-Chen ; McKay, Daniel J ; Peifer, Mark Katoh, Masaru (Editor)

PLoS ONE, 2012, Vol.7(2), p.e31284 [Peer Reviewed Journal]

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Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis

Tatomer, Deirdre C ; Terzo, Esteban ; Curry, Kaitlin P ; Salzler, Harmony ; Sabath, Ivan ; Zapotoczny, Grzegorz ; Mckay, Daniel J ; Dominski, Zbigniew ; Marzluff, William F ; Duronio, Robert J

The Journal of cell biology, 06 June 2016, Vol.213(5), pp.557-70 [Peer Reviewed Journal]

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Uncoupling the Structure-Activity Relationships of β2 Adrenergic Receptor Ligands from Membrane Binding

Dickson, Callum J ; Hornak, Viktor ; Velez-Vega, Camilo ; Mckay, Daniel J J ; Reilly, John ; Sandham, David A ; Shaw, Duncan ; Fairhurst, Robin A ; Charlton, Steven J ; Sykes, David A ; Pearlstein, Robert A ; Duca, Jose S

Journal of medicinal chemistry, 23 June 2016, Vol.59(12), pp.5780-9 [Peer Reviewed Journal]

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Practical synthesis of a renin inhibitor via a diastereoselective Dieckmann cyclization

Gauvreau, Danny ; Hughes, Greg J ; Lau, Stephen Y W ; Mckay, Daniel J ; O'Shea, Paul D ; Sidler, Rick R ; Yu, Bing ; Davies, Ian W

Organic letters, 19 November 2010, Vol.12(22), pp.5146-9 [Peer Reviewed Journal]

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Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila

Angelopoulos, Marios ; McKay, Daniel J. ; Mann, Richard S.

2012

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Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila

Agelopoulos, Marios ; Mckay, Daniel j ; Mann, Richard s

Cell Reports, 19 April 2012, Vol.1(4), pp.350-359 [Peer Reviewed Journal]

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How Long Can You Make an Oxygen Chain?
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How Long Can You Make an Oxygen Chain?

Mckay, Daniel J. ; Wright, James S.

Journal of the American Chemical Society, 02/1998, Vol.120(5), pp.1003-1013 [Peer Reviewed Journal]

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Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells

Guo, Yongfeng ; Flegel, Kerry ; Kumar, Jayashree ; Mckay, Daniel J ; Buttitta, Laura A

Biology open, 15 November 2016, Vol.5(11), pp.1648-1661 [Peer Reviewed Journal]

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Chromatin profiling of Drosophila CNS subpopulations identifies active transcriptional enhancers

Pearson, Joseph C ; Mckay, Daniel J ; Lieb, Jason D ; Crews, Stephen T

Development (Cambridge, England), 15 October 2016, Vol.143(20), pp.3723-3732 [Peer Reviewed Journal]

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The origins of the Drosophila leg revealed by the cis-regulatory architecture of the Distalless gene

Mckay, Daniel J ; Estella, Carlos ; Mann, Richard S

Development (Cambridge, England), January 2009, Vol.136(1), pp.61-71 [Peer Reviewed Journal]

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Direct interrogation of the role of H3K9 in metazoan heterochromatin function

Penke, Taylor J R ; Mckay, Daniel J ; Strahl, Brian D ; Matera, A Gregory ; Duronio, Robert J

Genes & development, 15 August 2016, Vol.30(16), pp.1866-80 [Peer Reviewed Journal]

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Functional Redundancy of Variant and Canonical Histone H3 Lysine 9 Modification in

Penke, Taylor J R ; Mckay, Daniel J ; Strahl, Brian D ; Matera, A Gregory ; Duronio, Robert J

Genetics, January 2018, Vol.208(1), pp.229-244 [Peer Reviewed Journal]

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Time-averaged distributions of solute and solvent motions: exploring proton wires of GFP and PfM2DH

Velez-Vega, Camilo ; Mckay, Daniel J J ; Aravamuthan, Vibhas ; Pearlstein, Robert ; Duca, José S

Journal of chemical information and modeling, 22 December 2014, Vol.54(12), pp.3344-61 [Peer Reviewed Journal]

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15
Theoretical Calculation of Substituent Effects on the O−H Bond Strength of Phenolic Antioxidants Related to Vitamin E
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Theoretical Calculation of Substituent Effects on the O−H Bond Strength of Phenolic Antioxidants Related to Vitamin E

Wright, James S. ; Carpenter, David J. ; Mckay, Daniel J. ; Ingold, K. U.

Journal of the American Chemical Society, 05/1997, Vol.119(18), pp.4245-4252 [Peer Reviewed Journal]

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16
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Estimation of Solvation Entropy and Enthalpy via Analysis of Water Oxygen-Hydrogen Correlations

Velez-Vega, Camilo ; Mckay, Daniel J J ; Kurtzman, Tom ; Aravamuthan, Vibhas ; Pearlstein, Robert A ; Duca, José S

Journal of chemical theory and computation, 10 November 2015, Vol.11(11), pp.5090-102 [Peer Reviewed Journal]

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17
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Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity

Meers, Michael P ; Henriques, Telmo ; Lavender, Christopher A ; Mckay, Daniel J ; Strahl, Brian D ; Duronio, Robert J ; Adelman, Karen ; Matera, A Gregory

eLife, 27 March 2017, Vol.6 [Peer Reviewed Journal]

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18
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Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo

Schulz, Katharine N ; Bondra, Eliana R ; Moshe, Arbel ; Villalta, Jacqueline E ; Lieb, Jason D ; Kaplan, Tommy ; Mckay, Daniel J ; Harrison, Melissa M

Genome research, November 2015, Vol.25(11), pp.1715-26 [Peer Reviewed Journal]

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19
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Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in

Armstrong, Robin L ; Penke, Taylor J R ; Strahl, Brian D ; Matera, A Gregory ; Mckay, Daniel J ; Macalpine, David M ; Duronio, Robert J

Genome research, November 2018, Vol.28(11), pp.1688-1700 [Peer Reviewed Journal]

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20
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Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo

Schaefer, Kristina N ; Bonello, Teresa T ; Zhang, Shiping ; Williams, Clara E ; Roberts, David M ; Mckay, Daniel J ; Peifer, Mark

PLoS genetics, April 2018, Vol.14(4), pp.e1007339 [Peer Reviewed Journal]

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21
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Hormone-dependent control of developmental timing through regulation of chromatin accessibility

Uyehara, Christopher M ; Nystrom, Spencer L ; Niederhuber, Matthew J ; Leatham-Jensen, Mary ; Ma, Yiqin ; Buttitta, Laura A ; Mckay, Daniel J

Genes & development, 01 May 2017, Vol.31(9), pp.862-875 [Peer Reviewed Journal]

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22
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Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster

Meers, Michael P. ; Adelman, Karen ; Duronio, Robert J. ; Strahl, Brian D. ; Mckay, Daniel J. ; Matera, A. Gregory

Meers, Michael P., Karen Adelman, Robert J. Duronio, Brian D. Strahl, Daniel J. McKay, and A. Gregory Matera. 2018. “Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster.” BMC Genomics 19 (1): 157. doi:10.1186/s12864-018-4510-7. http://dx.doi.org/10.1186/s12864-018-4510-7. [Peer Reviewed Journal]

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23
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Enhancer identification and activity evaluation in the red flour beetle,

Lai, Yi-Ting ; Deem, Kevin D ; Borràs-Castells, Ferran ; Sambrani, Nagraj ; Rudolf, Heike ; Suryamohan, Kushal ; El-Sherif, Ezzat ; Halfon, Marc S ; Mckay, Daniel J ; Tomoyasu, Yoshinori

Development (Cambridge, England), 05 April 2018, Vol.145(7) [Peer Reviewed Journal]

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24
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Diastereoselective reductive amination of aryl trifluoromethyl ketones and alpha-amino esters

Hughes, Greg ; Devine, Paul N ; Naber, John R ; O'Shea, Paul D ; Foster, Bruce S ; Mckay, Daniel J ; Volante, R P

Angewandte Chemie (International ed. in English), 2007, Vol.46(11), pp.1839-42 [Peer Reviewed Journal]

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25
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Diastereoselective Reductive Amination of Aryl Trifluoromethyl Ketones and α‐Amino Esters

Hughes, Greg ; Devine, Paul N. ; Naber, John R. ; O' Shea, Paul D. ; Foster, Bruce S. ; Mckay, DanielJ. ; Volante, R.  P.

Angewandte Chemie International Edition, 05 March 2007, Vol.46(11), pp.1839-1842 [Peer Reviewed Journal]

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26
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Direct integration of Hox and segmentation gene inputs during Drosophila development

Gebelein, Brian ; Mckay, Daniel J ; Mann, Richard S

Nature, 07 October 2004, Vol.431(7009), pp.653-9 [Peer Reviewed Journal]

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27
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Changes in chromatin accessibility ensure robust cell cycle exit in terminally differentiated cells

Ma, Yiqin ; Mckay, Daniel J ; Buttitta, Laura

PLoS biology, September 2019, Vol.17(9), pp.e3000378 [Peer Reviewed Journal]

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28
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Advancements in mapping 3D genome architecture

Mckay, Daniel J ; Stutzman, Alexis V ; Dowen, Jill M

Methods [Peer Reviewed Journal]

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29
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Centrosome Loss Triggers a Transcriptional Program To Counter Apoptosis-Induced Oxidative Stress

Poulton, John S ; Mckay, Daniel J ; Peifer, Mark

Genetics, May 2019, Vol.212(1), pp.187-211 [Peer Reviewed Journal]

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30
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Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosis

Robichaud, Jöel ; Black, W Cameron ; Thérien, Michel ; Paquet, Julie ; Oballa, Renata M ; Bayly, Christopher I ; Mckay, Daniel J ; Wang, Qingping ; Isabel, Elise ; Léger, Serge ; Mellon, Christophe ; Kimmel, Donald B ; Wesolowski, Gregg ; Percival, M David ; Massé, Fréderic

Journal of medicinal chemistry, 23 October 2008, Vol.51(20), pp.6410-20 [Peer Reviewed Journal]

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31
β-Substituted Cyclohexanecarboxamide:  A Nonpeptidic Framework for the Design of Potent Inhibitors of Cathepsin K
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β-Substituted Cyclohexanecarboxamide:  A Nonpeptidic Framework for the Design of Potent Inhibitors of Cathepsin K

Crane, Sheldon N. ; Black, W. Cameron ; Palmer, James T. ; Davis, Dana E. ; Setti, Eduardo ; Robichaud, Joel ; Paquet, Julie ; Oballa, Renata M. ; Bayly, Christopher I. ; Mckay, Daniel J. ; Somoza, John R. ; Chauret, Natalie ; Seto, Carmai ; Scheigetz, John ; Wesolowski, Greg ; Massé, Frederic ; Desmarais, Sylvie ; Ouellet, Marc

Journal of Medicinal Chemistry, 02/2006, Vol.49(3), pp.1066-1079 [Peer Reviewed Journal]

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32
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Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K

Crane, Sheldon N ; Black, W Cameron ; Palmer, James T ; Davis, Dana E ; Setti, Eduardo ; Robichaud, Joel ; Paquet, Julie ; Oballa, Renata M ; Bayly, Christopher I ; Mckay, Daniel J ; Somoza, John R ; Chauret, Natalie ; Seto, Carmai ; Scheigetz, John ; Wesolowski, Greg ; Massé, Frederic ; Desmarais, Sylvie ; Ouellet, Marc

Journal of medicinal chemistry, 09 February 2006, Vol.49(3), pp.1066-79 [Peer Reviewed Journal]

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33
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The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor

Isabel, Elise ; Bateman, Kevin P ; Chauret, Nathalie ; Cromlish, Wanda ; Desmarais, Sylvie ; Duong, Le T ; Falgueyret, Jean-Pierre ; Gauthier, Jacques Yves ; Lamontagne, Sonia ; Lau, Cheuk K ; Léger, Serge ; Leriche, Tammy ; Lévesque, Jean-François ; Li, Chun Sing ; Massé, Frédéric

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(3), pp.887-892 [Peer Reviewed Journal]

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34
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Structure-Based and Property-Driven Optimization of -Aryl Imidazoles toward Potent and Selective Oral RORγt Inhibitors

Hoegenauer, Klemens ; Kallen, Joerg ; Jiménez-Núñez, Eloísa ; Strang, Ross ; Ertl, Peter ; Cooke, Nigel G ; Hintermann, Samuel ; Voegtle, Markus ; Betschart, Claudia ; Mckay, Daniel J J ; Wagner, Juergen ; Ottl, Johannes ; Beerli, Christian ; Billich, Andreas ; Dawson, Janet ; Kaupmann

Journal of medicinal chemistry, 03 December 2019 [Peer Reviewed Journal]

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35
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Transcription factors mediate long-range enhancer-promoter interactions

Nolis, Ilias K ; Mckay, Daniel J ; Mantouvalou, Eva ; Lomvardas, Stavros ; Merika, Menie ; Thanos, Dimitris

Proceedings of the National Academy of Sciences of the United States of America, 01 December 2009, Vol.106(48), pp.20222-7 [Peer Reviewed Journal]

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36
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Dodecahedral molecular nitrogen (N 20) and related structures

Wright, James S ; Mckay, Daniel J ; Dilabio, Gino A

Journal of Molecular Structure: THEOCHEM, 1998, Vol.424(1), pp.47-55 [Peer Reviewed Journal]

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37
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Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group

Bungard, Christopher J ; Williams, Peter D ; Ballard, Jeanine E ; Bennett, David J ; Beaulieu, Christian ; Bahnck-Teets, Carolyn ; Carroll, Steve S ; Chang, Ronald K ; Dubost, David C ; Fay, John F ; Diamond, Tracy L ; Greshock, Thomas J ; Hao, Li ; Holloway, M Katharine ; Felock, Peter J ; Gesell, Jennifer J ; Su, Hua-Poo ; Manikowski, Jesse J ; Mckay, Daniel J ; Miller

ACS medicinal chemistry letters, 14 July 2016, Vol.7(7), pp.702-7 [Peer Reviewed Journal]

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38
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Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax

Noro, Barbara ; Culi, Joaquim ; Mckay, Daniel J ; Zhang, Wen ; Mann, Richard S

Genes & development, 15 June 2006, Vol.20(12), pp.1636-50 [Peer Reviewed Journal]

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