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32 Results  for Everything (Includes Articles)

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1
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Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice

Shimada, Y ; Tanaka, R ; Shimura, H ; Yamashiro, K ; Urabe, T ; Hattori, N

Neuroscience, 10 October 2014, Vol.278, pp.113-121 [Peer Reviewed Journal]

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MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis

Suarez-Lopez, Lucia ; Sriram, Ganapathy ; Kong, Yi ; Morandell, Sandra ; Merrick, Karl ; Hernandez, Yuliana ; Haigis, Kevin ; Yaffe, Michael

Proceedings of the National Academy of Sciences of the United States of America, May 1, 2018, Vol.115(18), p.E4236 [Peer Reviewed Journal]

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Cell-penetrating peptides can confer biological function: Regulation of inflammatory cytokines in human monocytes by MK2 inhibitor peptides

Brugnano, Jamie L ; Chan, Burke K ; Seal, Brandon L ; Panitch, Alyssa

Journal of Controlled Release, 2011, Vol.155(2), pp.128-133 [Peer Reviewed Journal]

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4
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Peptide Inhibitors of MK2 Show Promise for Inhibition of Abdominal Adhesions

Ward, Brian C ; Kavalukas, Sandra ; Brugnano, Jamie ; Barbul, Adrian ; Panitch, Alyssa

Journal of Surgical Research, 2011, Vol.169(1), pp.e27-e36 [Peer Reviewed Journal]

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5
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Revisiting p53 for cancer-specific chemo- and radiotherapy: Ten years after

Beckta, Jason M ; Ahmad, Syed Farhan ; Yang, Hu ; Valerie, Kristoffer

Cell Cycle, 01 March 2014, Vol.13(5), pp.710-713 [Peer Reviewed Journal]

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6
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MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition

Xu, Lei ; Yates, Cecelia C ; Lockyer, Pamela ; Xie, Liang ; Bevilacqua, Ariana ; He, Jun ; Lander, Cynthia ; Patterson, Cam ; Willis, Monte

Journal of Molecular and Cellular Cardiology, December 2014, Vol.77, pp.86-101 [Peer Reviewed Journal]

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7
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Posttranscriptional regulation of gene expression – adding another layer of complexity to the DNA damage response

Jorge Eboucas ; Katja Ehöpker ; Shuhua Echen ; Grit Sophie Herter-Sprie ; Mladen Ejokic ; Arina Eriabinska ; Hans Christian Reinhardt

Frontiers in Genetics, 01 August 2012, Vol.3 [Peer Reviewed Journal]

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8
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Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

Zhan, Lixuan ; Liu, Liu ; Li, Kongping ; Wu, Baoxing ; Liu, Dandan ; Liang, Donghai ; Wen, Haixia ; Wang, Yanmei ; Sun, Weiwen ; Liao, Weiping ; Xu, En

Brain Pathology, November 2017, Vol.27(6), pp.822-838 [Peer Reviewed Journal]

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9
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Design, synthesis, and biological evaluation of aminopyrazine derivatives as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

Lin, Songnian ; Malkani, Sunita ; Lombardo, Matthew ; Yang, Lihu ; Mills, Sander G ; Chapman, Kevin ; Thompson, James E ; Zhang, Wen Xiao ; Wang, Ruixiu ; Cubbon, Rose M ; O’neill, Edward A ; Hale, Jeffrey J

Bioorganic & Medicinal Chemistry Letters, 15 November 2015, Vol.25(22), pp.5402-5408 [Peer Reviewed Journal]

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10
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MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay

Stoecklin, Georg ; Stubbs, Tiffany ; Kedersha, Nancy ; Wax, Stephen ; Rigby, William Fc ; Blackwell, T Keith ; Anderson, Paul

EMBO Journal, 24 March 2004, Vol.23(6), pp.1313-1324 [Peer Reviewed Journal]

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11
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DNA Repair Biomarkers XPF and Phospho-MAPKAP Kinase 2 Correlate with Clinical Outcome in Advanced Head and Neck Cancer

Seiwert, Tanguy ; Wang, Xiaozhe ; Heitmann, Jana ; Villegas-Bergazzi, Vivian ; Sprott, Kam ; Finn, Stephen ; O'Regan, Esther ; Farrow, Allan ; Weichselbaum, Ralph ; Lingen, Mark ; Cohen, Ezra ; Stenson, Kerstin ; Weaver, David ; Vokes, Everett

PLoS One, Jul 2014, Vol.9(7), p.e102112 [Peer Reviewed Journal]

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CREB is activated by UVC through a p38/HOG‐1‐dependent protein kinase

Iordanov, M. ; Bender, K. ; Ade, T. ; Schmid, W. ; Sachsenmaier, C. ; Engel, K. ; Gaestel, M. ; Rahmsdorf, H. J. ; Herrlich, P.

EMBO Journal, 01 March 1997, Vol.16(5), pp.1009-1022 [Peer Reviewed Journal]

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13
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Mitogen‐activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

Waskiewicz, Andrew Jan ; Flynn, Andrea ; Proud, Christopher G. ; Cooper, Jonathan A.

EMBO Journal, 15 April 1997, Vol.16(8), pp.1909-1920 [Peer Reviewed Journal]

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14
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The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism

Winzen, Reinhard ; Kracht, Michael ; Ritter, Birgit ; Wilhelm, Arno ; Chen, Chyi‐Ying A. ; Shyu, Ann‐Bin ; Müller, Monika ; Gaestel, Matthias ; Resch, Klaus ; Holtmann, Helmut

EMBO Journal, 15 September 1999, Vol.18(18), pp.4969-4980 [Peer Reviewed Journal]

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15
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Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts

Maulik, Nilanjana ; Watanabe, Masazumi ; Zu, You-Li ; Huang, Chi-Kuang ; Cordis, Gerald A ; Schley, James A ; Das, Dipak K

FEBS Letters, 1996, Vol.396(2), pp.233-237 [Peer Reviewed Journal]

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16
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Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

Lin, Songnian ; Lombardo, Matthew ; Malkani, Sunita ; Hale, Jeffrey J ; Mills, Sander G ; Chapman, Kevin ; Thompson, James E ; Zhang, Wen Xiao ; Wang, Ruixiu ; Cubbon, Rose M ; O’neill, Edward A ; Luell, Silvi ; Carballo-Jane, Ester ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(12), pp.3238-3242 [Peer Reviewed Journal]

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17
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The MAP kinase‐activated protein kinase 2 contains a proline‐rich SH3‐binding domain

Engel, Katrin ; Plath, Kathrin ; Gaestel, Matthias

FEBS Letters, 20 December 1993, Vol.336(1), pp.143-147 [Peer Reviewed Journal]

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18
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Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase

Müllers, Erik ; Silva Cascales, Helena ; Jaiswal, Himjyot ; Saurin, Adrian T ; Lindqvist, Arne

Cell cycle (Georgetown, Tex.), 2014, Vol.13(17), pp.2733-43 [Peer Reviewed Journal]

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19
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Mitogen-activated 3p kinase is active in the nucleus

Zakowski, Vera ; Keramas, Georgios ; Kilian, Karin ; Rapp, Ulf R ; Ludwig, Stephan

Experimental Cell Research, 2004, Vol.299(1), pp.101-109 [Peer Reviewed Journal]

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20
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Evidence for general stabilization of mRNAs in response to UV light

Bollig, Frank ; Winzen, Reinhard ; Kracht, Michael ; Ghebremedhin, Beniam ; Ritter, Birgit ; Wilhelm, Arno ; Resch, Klaus ; Holtmann, Helmut

European Journal of Biochemistry, December 2002, Vol.269(23), pp.5830-5839 [Peer Reviewed Journal]

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21
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Ischemic preconditioning involves dual cardio-protective axes with p38MAPK as upstream target

Nagy, Norbert ; Shiroto, Keisuke ; Malik, Gautam ; Huang, Chi-Kuang ; Gaestel, Mathias ; Abdellatif, Maha ; Tosaki, Arpad ; Maulik, Nilanjana ; Das, Dipak K

Journal of Molecular and Cellular Cardiology, 2007, Vol.42(5), pp.981-990 [Peer Reviewed Journal]

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22
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Novel tetrahydro-β-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

Trujillo, John I ; Meyers, Marvin J ; Anderson, David R ; Hegde, Shridhar ; Mahoney, Matthew W ; Vernier, William F ; Buchler, Ingrid P ; Wu, Kun K ; Yang, Syaluan ; Hartmann, Susan J ; Reitz, David B

Bioorganic & Medicinal Chemistry Letters, 15 August 2007, Vol.17(16), pp.4657-4663 [Peer Reviewed Journal]

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23
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MK2 –/– gene knockout mouse hearts carry anti-apoptotic signal and are resistant to ischemia reperfusion injury

Shiroto, Keisuke ; Otani, Hajime ; Yamamoto, Fumio ; Huang, Chi-Kuang ; Maulik, Nilanjana ; Das, Dipak K

Journal of Molecular and Cellular Cardiology, 2005, Vol.38(1), pp.93-97 [Peer Reviewed Journal]

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24
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Activation of Raf1 and the ERK pathway in response to l-ascorbic acid in acute myeloid leukemia cells

Park, Seyeon ; Park, Chan H ; Hahm, Eun-Ryeong ; Kim, Kihyun ; Kimler, Bruce F ; Lee, Sook J ; Park, Hye K ; Lee, Se-Hoon ; Kim, Won S ; Jung, Chul W ; Park, Keunchil ; Riordan, Hugh D ; Lee, Je-Ho

Cellular Signalling, 2005, Vol.17(1), pp.111-119 [Peer Reviewed Journal]

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25
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Phosphorylation-dependent structural alterations in the small hsp30 chaperone are associated with cellular recovery

Fernando, Pasan ; Megeney, Lynn A ; Heikkila, John J

Experimental Cell Research, 2003, Vol.286(2), pp.175-185 [Peer Reviewed Journal]

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26
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High Expression and Activation of MAP Kinase-activated Protein Kinase 2 in Cardiac Muscle Cells

Zu, You-Li ; Ai, Youxi ; Gilchrist, Annette ; Maulik, Nilanjana ; Watras, James ; Sha'Afi, Ramadan I ; Das, Dipak K ; Huang, Chi-Kuang

Journal of Molecular and Cellular Cardiology, August 1997, Vol.29(8), pp.2159-2168 [Peer Reviewed Journal]

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27
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Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor

Lopes, Luciana B ; Flynn, Charles ; Komalavilas, Padmini ; Panitch, Alyssa ; Brophy, Colleen M ; Seal, Brandon L

Biochemical and Biophysical Research Communications, 2009, Vol.382(3), pp.535-539 [Peer Reviewed Journal]

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28
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P66ShcA interacts with MAPKAP kinase 2 and regulates its activity

Yannoni, Yvonne M. ; Gaestel, Matthias ; Lin, Lih - Ling

FEBS Letters, 23 April 2004, Vol.564(1-2), pp.205-211 [Peer Reviewed Journal]

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29
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Affinity purification of ARE-binding proteins identifies poly(A)-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization

Bollig, Frank ; Winzen, Reinhard ; Gaestel, Matthias ; Kostka, Susanne ; Resch, Klaus ; Holtmann, Helmut

Biochemical and Biophysical Research Communications, 2003, Vol.301(3), pp.665-670 [Peer Reviewed Journal]

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30
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Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways

Cheung-Flynn, Joyce ; Alvis, Bret ; Hocking, Kyle ; Guth, Christy ; Luo, Weifeng ; Mccallister, Reid ; Chadalavada, Kalyan ; Polcz, Monica ; Komalavilas, Padmini ; Brophy, Colleen

PLoS One, Aug 2019, Vol.14(8), p.e0220893 [Peer Reviewed Journal]

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31
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Identification of a Phosphorylation Site on Skeletal Muscle Myosin Light Chain Kinase That Becomes Phosphorylated during Muscle Contraction

Haydon, Claire E ; Watt, Peter W ; Morrice, Nick ; Knebel, Axel ; Gaestel, Matthias ; Cohen, Philip

Archives of Biochemistry and Biophysics, 15 January 2002, Vol.397(2), pp.224-231 [Peer Reviewed Journal]

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32
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Reactive oxygen species function as second messenger during ischemic preconditioning of heart

Das, Dipak ; Maulik, Nilanjana ; Sato, Motoaki ; Ray, Partha

Molecular and Cellular Biochemistry, 1999, Vol.196(1), pp.59-67 [Peer Reviewed Journal]

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