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Reduction of microalbuminuria in patients with type 2 diabetes: the Shiga Microalbuminuria Reduction Trial (SMART)

Uzu, Takashi ; Sawaguchi, Makoto ; Maegawa, Hiroshi ; Kashiwagi, Atsunori

Diabetes care, June 2007, Vol.30(6), pp.1581-3 [Peer Reviewed Journal]

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Furosemide-associated nephrocalcinosis and renal cysts

Uzu, Takashi ; Araki, Shin-Ichi ; Isshiki, Keiji ; Maegawa, Hiroshi

Kidney International, 01 September 2011, Vol.80(5), pp.556-556 [Peer Reviewed Journal]

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Clinical inertia in basal insulin-treated patients with type 2 diabetes - Results from a retrospective database study in Japan (JDDM 43)

Satoh, Jo ; Andersen, Marc ; Bekker Hansen, Brian ; Larsen Thorsted, Brian ; Tutkunkardas, Deniz ; Zacho, Mette ; Maegawa, Hiroshi

PloS one, 2018, Vol.13(9), pp.e0198160 [Peer Reviewed Journal]

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Multiple osteoporotic fractures in a patient with CKD stage G3b

Uzu, Takashi ; Araki, Shin-Ichi ; Araki, Hisazumi ; Kume, Shinji ; Maegawa, Hiroshi

Kidney International, May 2015, Vol.87(5), pp.1077-1077 [Peer Reviewed Journal]

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Gene Therapy for Neuropathic Pain by Silencing of TNF-α Expression with Lentiviral Vectors Targeting the Dorsal Root Ganglion in Mice

Ogawa, Nobuhiro ; Kawai, Hiromichi ; Terashima, Tomoya ; Kojima, Hideto ; Oka, Kazuhiro ; Chan, Lawrence ; Maegawa, Hiroshi

PLoS One, Mar 2014, Vol.9(3), p.e92073 [Peer Reviewed Journal]

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Improved glucose metabolism by Eragrostis tef potentially through beige adipocyte formation and attenuating adipose tissue inflammation

Lemecha, Mengistu ; Morino, Katsutaro ; Seifu, Daniel ; Imamura, Takeshi ; Nakagawa, Fumiyuki ; Nagata, Aki ; Okamato, Takuya ; Sekine, Osamu ; Ugi, Satoshi ; Maegawa, Hiroshi

PloS one, 2018, Vol.13(8), pp.e0201661 [Peer Reviewed Journal]

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Association of New Loci Identified in European Genome-Wide Association Studies with Susceptibility to Type 2 Diabetes in the Japanese (Replication Study for Type 2 Diabetes Loci)

Ohshige, Toshihiko ; Iwata, Minoru ; Omori, Shintaro ; Tanaka, Yasushi ; Hirose, Hiroshi ; Kaku, Kohei ; Maegawa, Hiroshi ; Watada, Hirotaka ; Kashiwagi, Atsunori ; Kawamori, Ryuzo ; Tobe, Kazuyuki ; Kadowaki, Takashi ; Nakamura, Yusuke ; Maeda, Shiro Ahmed, Niyaz (Editor)

PLoS ONE, 2011, Vol.6(10), p.e26911 [Peer Reviewed Journal]

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A Single Nucleotide Polymorphism within DUSP9 Is Associated with Susceptibility to Type 2 Diabetes in a Japanese Population ( DUSP9 and Susceptibility to Type 2 Diabetes)

Fukuda, Hisashi ; Imamura, Minako ; Tanaka, Yasushi ; Iwata, Minoru ; Hirose, Hiroshi ; Kaku, Kohei ; Maegawa, Hiroshi ; Watada, Hirotaka ; Tobe, Kazuyuki ; Kashiwagi, Atsunori ; Kawamori, Ryuzo ; Maeda, Shiro Prokunina-olsson, Ludmila (Editor)

2012, Vol.7(9), p.e46263 [Peer Reviewed Journal]

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9
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GW501516, a PPARδ Agonist, Ameliorates Tubulointerstitial Inflammation in Proteinuric Kidney Disease via Inhibition of TAK1-NFκB Pathway in Mice (PPARδ Agonist in Proteinuric Kidney Disease)

Yang, Xu ; Kume, Shinji ; Tanaka, Yuki ; Isshiki, Keiji ; Araki, Shin-ichi ; Chin-Kanasaki, Masami ; Sugimoto, Toshiro ; Koya, Daisuke ; Haneda, Masakazu ; Sugaya, Takeshi ; Li, Detian ; Han, Ping ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Maegawa, Hiroshi ; Uzu, Takashi Chatziantoniou, Christos (Editor)

PLoS ONE, 2011, Vol.6(9), p.e25271 [Peer Reviewed Journal]

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Replication Study for the Association of 9 East Asian GWAS-Derived Loci with Susceptibility to Type 2 Diabetes in a Japanese Population (East Asian Type 2 Diabetes Loci in the Japanese)

Sakai, Kensuke ; Imamura, Minako ; Tanaka, Yasushi ; Iwata, Minoru ; Hirose, Hiroshi ; Kaku, Kohei ; Maegawa, Hiroshi ; Watada, Hirotaka ; Tobe, Kazuyuki ; Kashiwagi, Atsunori ; Kawamori, Ryuzo ; Maeda, Shiro Dotta, Francesco (Editor)

2013, Vol.8(9), p.e76317 [Peer Reviewed Journal]

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11
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Predictive effects of urinary liver-type fatty acid-binding protein for deteriorating renal function and incidence of cardiovascular disease in type 2 diabetic patients without advanced nephropathy

Araki, Shin-Ichi ; Haneda, Masakazu ; Koya, Daisuke ; Sugaya, Takeshi ; Isshiki, Keiji ; Kume, Shinji ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

Diabetes care, May 2013, Vol.36(5), pp.1248-53 [Peer Reviewed Journal]

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12
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Hyperglycemia induces abnormal gene expression in hematopoietic stem cells and their progeny in diabetic neuropathy

Katagi, Miwako ; Terashima, Tomoya ; Okano, Junko ; Urabe, Hiroshi ; Nakae, Yuki ; Ogawa, Nobuhiro ; Udagawa, Jun ; Maegawa, Hiroshi ; Matsumura, Kazuhiro ; Chan, Lawrence ; Kojima, Hideto

FEBS Letters, 18 March 2014, Vol.588(6), pp.1080-1086 [Peer Reviewed Journal]

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13
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Pivotal Role of -GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis

Ohashi, Natsuko ; Morino, Katsutaro ; Ida, Shogo ; Sekine, Osamu ; Lemecha, Mengistu ; Kume, Shinji ; Park, Shi-Young ; Choi, Cheol Soo ; Ugi, Satoshi ; Maegawa, Hiroshi

Diabetes, September 2017, Vol.66(9), pp.2351-2362 [Peer Reviewed Journal]

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14
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Hyperglycemia Induces Skin Barrier Dysfunctions with Impairment of Epidermal Integrity in Non-Wounded Skin of Type 1 Diabetic Mice

Okano, Junko ; Kojima, Hideto ; Katagi, Miwako ; Nakagawa, Takahiko ; Nakae, Yuki ; Terashima, Tomoya ; Kurakane, Takeshi ; Kubota, Mamoru ; Maegawa, Hiroshi ; Udagawa, Jun

PLoS One, Nov 2016, Vol.11(11), p.e0166215 [Peer Reviewed Journal]

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15
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Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies

Matsuba, Ren ; Imamura, Minako ; Tanaka, Yasushi ; Iwata, Minoru ; Hirose, Hiroshi ; Kaku, Kohei ; Maegawa, Hiroshi ; Watada, Hirotaka ; Tobe, Kazuyuki ; Kashiwagi, Atsunori ; Kawamori, Ryuzo ; Maeda, Shiro Palmer, Nicholette D. (editor)

PLoS ONE, 2016, Vol.11(4) [Peer Reviewed Journal]

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16
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Predictors for Mild and Severe Hypoglycemia in Insulin-Treated Japanese Diabetic Patients

Sonoda, Nao ; Morimoto, Akiko ; Ugi, Satoshi ; Morino, Katsutaro ; Sekine, Osamu ; Nemoto, Ken-Ichi ; Godai, Kayo ; Maegawa, Hiroshi ; Miyamatsu, Naomi

PLoS One, Jun 2015, Vol.10(6), p.e0130584 [Peer Reviewed Journal]

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17
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Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial

Araki, Eiichi ; Yamashita, Shizuya ; Arai, Hidenori ; Yokote, Koutaro ; Satoh, Jo ; Inoguchi, Toyoshi ; Nakamura, Jiro ; Maegawa, Hiroshi ; Yoshioka, Narihito ; Tanizawa, Yukio ; Watada, Hirotaka ; Suganami, Hideki ; Ishibashi, Shun

Diabetes care, March 2018, Vol.41(3), pp.538-546 [Peer Reviewed Journal]

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18
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Presence and functional role of the rapidly activating delayed rectifier K + current in left and right atria of adult mice

Nakamura, Hiroko ; Ding, Wei-Guang ; Sanada, Mitsuru ; Maeda, Kengo ; Kawai, Hiromichi ; Maegawa, Hiroshi ; Matsuura, Hiroshi

European Journal of Pharmacology, 2010, Vol.649(1), pp.14-22 [Peer Reviewed Journal]

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19
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Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

Tagawa, Atsuko ; Yasuda, Mako ; Kume, Shinji ; Yamahara, Kosuke ; Nakazawa, Jun ; Chin-Kanasaki, Masami ; Araki, Hisazumi ; Araki, Shin-Ichi ; Koya, Daisuke ; Asanuma, Katsuhiko ; Kim, Eun-Hee ; Haneda, Masakazu ; Kajiwara, Nobuyuki ; Hayashi, Kazuyuki ; Ohashi, Hiroshi ; Ugi, Satoshi ; Maegawa, Hiroshi ; Uzu, Takashi

Diabetes, March 2016, Vol.65(3), pp.755-67 [Peer Reviewed Journal]

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20
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Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes

Morino, Katsutaro ; Petersen, Kitt Falk ; Sono, Saki ; Choi, Cheol Soo ; Samuel, Varman T ; Lin, Aiping ; Gallo, Amy ; Zhao, Hongyu ; Kashiwagi, Atsunori ; Goldberg, Ira J ; Wang, Hong ; Eckel, Robert H ; Maegawa, Hiroshi ; Shulman, Gerald I

Diabetes, April 2012, Vol.61(4), pp.877-87 [Peer Reviewed Journal]

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21
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Association between urinary type IV collagen level and deterioration of renal function in type 2 diabetic patients without overt proteinuria

Araki, Shin-Ichi ; Haneda, Masakazu ; Koya, Daisuke ; Isshiki, Keiji ; Kume, Shinji ; Sugimoto, Toshiro ; Kawai, Hiromichi ; Nishio, Yoshihiko ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

Diabetes care, August 2010, Vol.33(8), pp.1805-10 [Peer Reviewed Journal]

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22
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Emerging role of mammalian autophagy in ketogenesis to overcome starvation

Takagi, Ayano ; Kume, Shinji ; Maegawa, Hiroshi ; Uzu, Takashi

Autophagy, 02 April 2016, Vol.12(4), pp.709-710 [Peer Reviewed Journal]

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23
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Role of Nutrient-Sensing Signals in the Pathogenesis of Diabetic Nephropathy

Kume, Shinji ; Koya, Daisuke ; Uzu, Takashi ; Maegawa, Hiroshi

BioMed Research International, 2014, Vol.2014 [Peer Reviewed Journal]

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24
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Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

Tanaka, Yuki ; Kume, Shinji ; Araki, Shin-Ichi ; Isshiki, Keiji ; Chin-Kanasaki, Masami ; Sakaguchi, Masayoshi ; Sugimoto, Toshiro ; Koya, Daisuke ; Haneda, Masakazu ; Kashiwagi, Atsunori ; Maegawa, Hiroshi ; Uzu, Takashi

Kidney International, 02 April 2011, Vol.79(8), pp.871-882 [Peer Reviewed Journal]

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25
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Enhanced Intestinal Motility during Oral Glucose Tolerance Test after Laparoscopic Sleeve Gastrectomy: Preliminary Results Using Cine Magnetic Resonance Imaging

Vo, Nguyen ; Yamamoto, Hiroshi ; Furukawa, Akira ; Yamaguchi, Tsuyoshi ; Murata, Satoshi ; Yoshimura, Masahiro ; Murakami, Yoko ; Sato, Shigetaka ; Otani, Hideji ; Ugi, Satoshi ; Morino, Katsutaro ; Maegawa, Hiroshi ; Tani, Tohru

PLoS One, Jun 2013, Vol.8(6), p.e65739 [Peer Reviewed Journal]

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26
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Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes

Matsuba, Ren ; Sakai, Kensuke ; Imamura, Minako ; Tanaka, Yasushi ; Iwata, Minoru ; Hirose, Hiroshi ; Kaku, Kohei ; Maegawa, Hiroshi ; Watada, Hirotaka ; Tobe, Kazuyuki ; Kashiwagi, Atsunori ; Kawamori, Ryuzo ; Maeda, Shiro

PLoS One, May 2015, Vol.10(5), p.e0126363 [Peer Reviewed Journal]

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27
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4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation

Ishikado, Atsushi ; Morino, Katsutaro ; Nishio, Yoshihiko ; Nakagawa, Fumiyuki ; Mukose, Atsushi ; Sono, Yoko ; Yoshioka, Nagisa ; Kondo, Keiko ; Sekine, Osamu ; Yoshizaki, Takeshi ; Ugi, Satoshi ; Uzu, Takashi ; Kawai, Hiromichi ; Makino, Taketoshi ; Okamura, Tomio ; Yamamoto, Masayuki ; Kashiwagi, Atsunori ; Maegawa, Hiroshi Schunck, Wolf-Hagen (editor)

PLoS ONE, 2013, Vol.8(7) [Peer Reviewed Journal]

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28
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Fiber-rich diet with brown rice improves endothelial function in type 2 diabetes mellitus: A randomized controlled trial

Kondo, Keiko ; Morino, Katsutaro ; Nishio, Yoshihiko ; Ishikado, Atsushi ; Arima, Hisatomi ; Nakao, Keiko ; Nakagawa, Fumiyuki ; Nikami, Fumio ; Sekine, Osamu ; Nemoto, Ken-Ichi ; Suwa, Makoto ; Matsumoto, Motonobu ; Miura, Katsuyuki ; Makino, Taketoshi ; Ugi, Satoshi ; Maegawa, Hiroshi

PLoS One, Jun 2017, Vol.12(6), p.e0179869 [Peer Reviewed Journal]

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29
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Predictive Properties of Plasma Amino Acid Profile for Cardiovascular Disease in Patients with Type 2 Diabetes

Kume, Shinji ; Araki, Shin-Ichi ; Ono, Nobukazu ; Shinhara, Atsuko ; Muramatsu, Takahiko ; Araki, Hisazumi ; Isshiki, Keiji ; Nakamura, Kazuki ; Miyano, Hiroshi ; Koya, Daisuke ; Haneda, Masakazu ; Ugi, Satoshi ; Kawai, Hiromichi ; Kashiwagi, Atsunori ; Uzu, Takashi ; Maegawa, Hiroshi

PLoS One, Jun 2014, Vol.9(6), p.e101219 [Peer Reviewed Journal]

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30
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The Influence of a Single Nucleotide Polymorphism within CNDP1 on Susceptibility to Diabetic Nephropathy in Japanese Women with Type 2 Diabetes

Kurashige, Mahiro ; Imamura, Minako ; Araki, Shin-Ichi ; Suzuki, Daisuke ; Babazono, Tetsuya ; Uzu, Takashi ; Umezono, Tomoya ; Toyoda, Masao ; Kawai, Koichi ; Imanishi, Masahito ; Hanaoka, Kazushige ; Maegawa, Hiroshi ; Uchigata, Yasuko ; Hosoya, Tatsuo ; Maeda, Shiro

PLoS One, Jan 2013, Vol.8(1), p.e54064 [Peer Reviewed Journal]

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31
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A Mutation of COX6A1 Causes a Recessive Axonal or Mixed Form of Charcot-Marie-Tooth Disease

Tamiya, Gen ; Makino, Satoshi ; Hayashi, Makiko ; Abe, Akiko ; Numakura, Chikahiko ; Ueki, Masao ; Tanaka, Atsushi ; Ito, Chizuru ; Toshimori, Kiyotaka ; Ogawa, Nobuhiro ; Terashima, Tomoya ; Maegawa, Hiroshi ; Yanagisawa, Daijiro ; Tooyama, Ikuo ; Tada, Masayoshi ; Onodera, Osamu ; Hayasaka, Kiyoshi

The American Journal of Human Genetics, 04 September 2014, Vol.95(3), pp.294-300 [Peer Reviewed Journal]

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32
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CCDC3 is specifically upregulated in omental adipose tissue in subjects with abdominal obesity

Ugi, Satoshi ; Maeda, Shiro ; Kawamura, Yoshihiro ; Kobayashi, Masa‐Aki ; Imamura, Minako ; Yoshizaki, Takeshi ; Morino, Katsutaro ; Sekine, Osamu ; Yamamoto, Hiroshi ; Tani, Toru ; Rokushima, Masatomo ; Kashiwagi, Atsunori ; Maegawa, Hiroshi

Obesity, April 2014, Vol.22(4), pp.1070-1077 [Peer Reviewed Journal]

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33
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The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

Yamahara, Kosuke ; Yasuda, Mako ; Kume, Shinji ; Koya, Daisuke ; Maegawa, Hiroshi ; Uzu, Takashi Kanasaki, Keizo

Journal of Diabetes Research, 2013, Vol.2013, 9 pages [Peer Reviewed Journal]

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34
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Emerging role of podocyte autophagy in the progression of diabetic nephropathy

Yasuda-Yamahara, Mako ; Kume, Shinji ; Tagawa, Atsuko ; Maegawa, Hiroshi ; Uzu, Takashi

Autophagy, 01 December 2015, Vol.11(12), pp.2385-2386 [Peer Reviewed Journal]

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35
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Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial

Uzu, Takashi ; Araki, Shin-Ichi ; Kashiwagi, Atsunori ; Haneda, Masakazu ; Koya, Daisuke ; Yokoyama, Hiroki ; Kida, Yasuo ; Ikebuchi, Motoyoshi ; Nakamura, Takaaki ; Nishimura, Masataka ; Takahara, Noriko ; Obata, Toshiyuki ; Omichi, Nobuyuki ; Sakamoto, Katsuhiko ; Shingu, Ryosuke ; Taki, Hideki ; Nagai, Yoshio ; Tokuda, Hiroaki ; Kitada, Munehiro ; Misawa

PLoS One, Dec 2016, Vol.11(12), p.e0164936 [Peer Reviewed Journal]

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