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14 Results  for Everything (Includes Articles)

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Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection

Gardelli, Cristina ; Attenni, Barbara ; Donghi, Monica ; Meppen, Malte ; Pacini, Barbara ; Harper, Steven ; Di Marco, Annalise ; Fiore, Fabrizio ; Giuliano, Claudio ; Pucci, Vincenzo ; Laufer, Ralph ; Gennari, Nadia ; Marcucci, Isabella ; Leone, Joseph F ; Olsen, David B ; Maccoss, Malcolm ; Rowley, Michael ; Narjes, Frank

Journal of medicinal chemistry, 10 September 2009, Vol.52(17), pp.5394-407 [Peer Reviewed Journal]

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Synthesis of 2′-β- C-methyl-neplanocin derivatives as anti-HCV agents

Liao, Xibin ; Butora, Gabor ; Olsen, David B ; Carroll, Steven S ; Mcmasters, Daniel R ; Leone, Joseph F ; Stahlhut, Mark ; Doss, George A ; Yang, Lihu ; Maccoss, Malcolm

Tetrahedron Letters, 2008, Vol.49(26), pp.4149-4152 [Peer Reviewed Journal]

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Approaches to installing a N- gem-dimethylmethylene-2-oxazolyl group and application to the synthesis of a second generation HIV protease inhibitor

Ikemoto, Norihiro ; Miller, Ross A ; Fleitz, Fred J ; Liu, Jinchu ; Petrillo, Daniel E ; Leone, Joseph F ; Laquidara, Joseph ; Marcune, Benjamin ; Karady, Sandor ; Armstrong, Joseph D ; Volante, Ralph P

Tetrahedron Letters, 2005, Vol.46(11), pp.1867-1871 [Peer Reviewed Journal]

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Synthesis and HCV inhibitory properties of 9-deaza- and 7,9-dideaza-7-oxa-2′- C-methyladenosine

Butora, Gabor ; Olsen, David B ; Carroll, Steven S ; Mcmasters, Daniel R ; Schmitt, Christoph ; Leone, Joseph F ; Stahlhut, Mark ; Burlein, Christine ; Maccoss, Malcolm

Bioorganic & Medicinal Chemistry, 2007, Vol.15(15), pp.5219-5229 [Peer Reviewed Journal]

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Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain

Chobanian, Harry R ; Guo, Yan ; Liu, Ping ; Chioda, Marc D ; Fung, Selena ; Lanza, Thomas J ; Chang, Linda ; Bakshi, Raman K ; Dellureficio, James P ; Hong, Qingmei ; Mclaughlin, Mark ; Belyk, Kevin M ; Krska, Shane W ; Makarewicz, Amanda K ; Martel, Elliot J ; Leone, Joseph F ; Frey, Lisa ; Karanam, Bindhu ; Madeira, Maria ; Alvaro

ACS medicinal chemistry letters, 12 June 2014, Vol.5(6), pp.717-21 [Peer Reviewed Journal]

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(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-1,2,4triazolo1,5-a-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

Edmondson, Scott D ; Mastracchio, Anthony ; Mathvink, Robert J ; He, Jiafang ; Harper, Bart ; Park, You-Jung ; Beconi, Maria ; Di Salvo, Jerry ; Eiermann, George J ; He, Huaibing ; Leiting, Barbara ; Leone, Joseph F ; Levorse, Dorothy A ; Lyons, Kathryn ; Patel, Reshma A ; Patel, Sangita B ; Petrov, Aleksandr ; Scapin, Giovanna ; Shang, Jackie ; Roy

Journal of medicinal chemistry, 15 June 2006, Vol.49(12), pp.3614-27 [Peer Reviewed Journal]

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HILIC LC‐MS for the determination of 2′‐ C ‐methyl‐cytidine‐triphosphate in rat liver

Pucci, Vincenzo ; Giuliano, Claudio ; Zhang, Rena ; Koeplinger, Kenneth Alan ; Leone, Joseph F. ; Monteagudo, Edith ; Bonelli, Fabio

Journal of Separation Science, May 2009, Vol.32(9), pp.1275-1283 [Peer Reviewed Journal]

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Synthesis and evaluation of novel phosphoramidate prodrugs of 2′-methyl cytidine as inhibitors of hepatitis c virus NS5B polymerase

Donghi, Monica ; Attenni, Barbara ; Gardelli, Cristina ; Marco, Annalise Di ; Fiore, Fabrizio ; Giuliano, Claudio ; Laufer, Ralph ; Leone, Joseph F ; Pucci, Vincenzo ; Rowley, Michael ; Narjes, Frank

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(5), pp.1392-1395 [Peer Reviewed Journal]

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Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase

Liu, Ping ; Hamill, Terence G ; Chioda, Marc ; Chobanian, Harry ; Fung, Selena ; Guo, Yan ; Chang, Linda ; Bakshi, Raman ; Hong, Qingmei ; Dellureficio, James ; Lin, Linus S ; Abbadie, Catherine ; Alexander, Jessica ; Jin, Hong ; Mandala, Suzanne ; Shiao, Lin-Lin ; Li, Wenping ; Sanabria, Sandra ; Williams, David ; Zeng

ACS medicinal chemistry letters, 13 June 2013, Vol.4(6), pp.509-13 [Peer Reviewed Journal]

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Multiple strategies for the preparation of a sulfur-35 labeled NPC1L1 radioligand

Simeone, Joseph P ; Braun, Matthew P ; Leone, Joseph F ; Lin, Peter ; Devita, Robert J ; Garcia-Calvo, Margarita ; Bull, Herb G ; Lisnock, Jeanmarie ; Dean, Dennis C

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(17), pp.5033-5036 [Peer Reviewed Journal]

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Cyclic phosphoramidates as prodrugs of 2′- C-methylcytidine

Meppen, Malte ; Pacini, Barbara ; Bazzo, Renzo ; Koch, Uwe ; Leone, Joseph F ; Koeplinger, Kenneth A ; Rowley, Michael ; Altamura, Sergio ; Di Marco, Annalise ; Fiore, Fabrizio ; Giuliano, Claudio ; Gonzalez-Paz, Odalys ; Laufer, Ralph ; Pucci, Vincenzo ; Narjes, Frank ; Gardelli, Cristina

European Journal of Medicinal Chemistry, 2009, Vol.44(9), pp.3765-3770 [Peer Reviewed Journal]

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Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors

Xu, Jinyou ; Wei, Lan ; Mathvink, Robert J ; Edmondson, Scott D ; Eiermann, George J ; He, Huaibing ; Leone, Joseph F ; Leiting, Barbara ; Lyons, Kathryn A ; Marsilio, Frank ; Patel, Reshma A ; Patel, Sangita B ; Petrov, Aleksandr ; Scapin, Giovanna ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(20), pp.5373-5377 [Peer Reviewed Journal]

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Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors

Xu, Jinyou ; Wei, Lan ; Mathvink, Robert ; Edmondson, Scott D ; Mastracchio, Anthony ; Eiermann, George J ; He, Huaibing ; Leone, Joseph F ; Leiting, Barbara ; Lyons, Kathryn A ; Marsilio, Frank ; Patel, Reshma A ; Petrov, Aleksandr ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(5), pp.1346-1349 [Peer Reviewed Journal]

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Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors

Edmondson, Scott D ; Mastracchio, Anthony ; Duffy, Joseph L ; Eiermann, George J ; He, Huaibing ; Ita, Ida ; Leiting, Barbara ; Leone, Joseph F ; Lyons, Kathryn A ; Makarewicz, Amanda M ; Patel, Reshma A ; Petrov, Aleksandr ; Wu, Joseph K ; Thornberry, Nancy A ; Weber, Ann E

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(12), pp.3048-3052 [Peer Reviewed Journal]

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