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1
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A modified Curtius reaction: an efficient and simple method for direct isolation of free amine

Ma, Bin ; Lee, Wen-Cherng

Tetrahedron Letters, 2010, Vol.51(2), pp.385-386 [Peer Reviewed Journal]

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2
Corrections to Heat Shock Protein 90: Inhibitors in Clinical Trials
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Corrections to Heat Shock Protein 90: Inhibitors in Clinical Trials

Biamonte, Marco A. ; Van de Water, Ryan ; Arndt, Joseph W. ; Scannevin, Robert H. ; Perret, Daniel ; Lee, Wen-Cherng

Journal of Medicinal Chemistry, 03/11/2010, Vol.53(5), pp.2332-2332 [Peer Reviewed Journal]

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3
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Heat shock protein 90: inhibitors in clinical trials

Biamonte, Marco A ; Van De Water, Ryan ; Arndt, Joseph W ; Scannevin, Robert H ; Perret, Daniel ; Lee, Wen-Cherng

Journal of medicinal chemistry, 14 January 2010, Vol.53(1), pp.3-17 [Peer Reviewed Journal]

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4
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Effect of metal counterions on the stereoselectivity of aldol reactions used to assemble the seco acid backbone of erythromycin b

Martin, Stephen F ; Lee, Wen-Cherng

Tetrahedron Letters, 1993, Vol.34(17), pp.2711-2714 [Peer Reviewed Journal]

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5
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Pyrazolone based TGFβR1 kinase inhibitors

Guckian, Kevin ; Carter, Mary Beth ; Lin, Edward Yin-Shiang ; Choi, Michael ; Sun, Lihong ; Boriack-Sjodin, P. Ann ; Chuaqui, Claudio ; Lane, Benjamin ; Cheung, Kam ; Ling, Leona ; Lee, Wen-Cherng

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(1), pp.326-329 [Peer Reviewed Journal]

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6
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An Abiotic Strategy for the Enantioselective Synthesis of Erythromycin B

Hergenrother, Paul J. ; Hodgson, Anne ; Judd, Andrew S. ; Lee, WenCherng ; Martin, Stephen F.

Angewandte Chemie International Edition, 21 July 2003, Vol.42(28), pp.3278-3281 [Peer Reviewed Journal]

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7
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Total synthesis of erythromycin B

Breton, Philippe ; Hergenrother, Paul J ; Hida, Tsuneaki ; Hodgson, Anne ; Judd, Andrew S ; Kraynack, Erica ; Kym, Philip R ; Lee, Wen-Cherng ; Loft, Michael S ; Yamashita, Masayuki ; Martin, Stephen F

Tetrahedron, 2007, Vol.63(26), pp.5709-5729 [Peer Reviewed Journal]

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8
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A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection

Suzuki, Eiji ; Kim, Samuel ; Cheung, H-Kam ; Corbley, Michael J ; Zhang, Xiamei ; Sun, Lihong ; Shan, Feng ; Singh, Juswinder ; Lee, Wen-Cherng ; Albelda, Steven M ; Ling, Leona E

Cancer research, 01 March 2007, Vol.67(5), pp.2351-9 [Peer Reviewed Journal]

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9
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Identification of potent and novel alpha4beta1 antagonists using in silico screening

Singh, Juswinder ; Van Vlijmen, Herman ; Liao, Yusheng ; Lee, Wen-Cherng ; Cornebise, Mark ; Harris, Mary ; Shu, I-Hsiang ; Gill, Alan ; Cuervo, Julio H ; Abraham, William M ; Adams, Steven P

Journal of medicinal chemistry, 04 July 2002, Vol.45(14), pp.2988-93 [Peer Reviewed Journal]

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10
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Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery

Erlanson, Daniel A ; Arndt, Joseph W ; Cancilla, Mark T ; Cao, Kathy ; Elling, Robert A ; English, Nicki ; Friedman, Jessica ; Hansen, Stig K ; Hession, Cathy ; Joseph, Ingrid ; Kumaravel, Gnanasambandam ; Lee, Wen-Cherng ; Lind, Ken E ; Mcdowell, Robert S ; Miatkowski, Konrad ; Nguyen, Christine ; Nguyen, Thinh B ; Park, Sophia ; Pathan, Nuzhat ; Penny, David M ; Romanowski, Michael J ; Scott, Daniel ; Silvian, Laura ; Simmons, Robert L ; Tangonan, Bradley T ; Yang, Wenjin ; Sun, Lihong

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(10), pp.3078-3083 [Peer Reviewed Journal]

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11
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Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I)

Zhang, Lin ; Fan, Junhua ; Chong, Jer-Hong ; Cesena, Angela ; Tam, Betty Y.Y ; Gilson, Charles ; Boykin, Christina ; Wang, Deping ; Aivazian, Dikran ; Marcotte, Doug ; Xiao, Guangqing ; Le Brazidec, Jean-Yves ; Piao, Jinhua ; Lundgren, Karen ; Hong, Kevin ; Vu, Khang ; Nguyen, Khanh ; Gan, Liang-Shang ; Silvian, Laura ; Ling, Leona ; Teng, Min ; Reff, Mitchell ; Takeda, Nicole ; Timple, Noel ; Wang, Qin ; Morena, Ron ; Khan, Samina ; Zhao, Shuo ; Li, Tony ; Lee, Wen-Cherng ; Taveras, Arthur G ; Chao, Jianhua

Bioorganic & Medicinal Chemistry Letters, 15 September 2011, Vol.21(18), pp.5633-5637 [Peer Reviewed Journal]

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12
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Stereochemistry–activity relationship of orally active tetralin S1P agonist prodrugs

Ma, Bin ; Guckian, Kevin M ; Lin, Edward Yin-Shiang ; Lee, Wen-Cherng ; Scott, Daniel ; Kumaravel, Gnanasambandam ; Macdonald, Timothy L ; Lynch, Kevin R ; Black, Cheryl ; Chollate, Sowmya ; Hahm, Kyungmin ; Hetu, Gregg ; Jin, Ping ; Luo, Yi ; Rohde, Ellen ; Rossomando, Anthony ; Scannevin, Robert ; Wang, Joy ; Yang, Chunhua

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(7), pp.2264-2269 [Peer Reviewed Journal]

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13
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An Abiotic Strategy for the Enantioselective Synthesis of Erythromycin B

Hergenrother, Paul J. ; Hodgson, Anne ; Judd, Andrew S. ; Lee, WenCherng ; Martin, Stephen F.

Angewandte Chemie, 21 July 2003, Vol.115(28), pp.3400-3403 [Peer Reviewed Journal]

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14
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2-Aminoimidazoles inhibitors of TGF-β receptor 1

Bonafoux, Dominique ; Chuaqui, Claudio ; Boriack-Sjodin, P. Ann ; Fitch, Chris ; Hankins, Gretchen ; Josiah, Serene ; Black, Cheryl ; Hetu, Gregg ; Ling, Leona ; Lee, Wen-Cherng

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(3), pp.912-916 [Peer Reviewed Journal]

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15
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A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence

Egger, Linda A ; Cao, Jin ; Mccallum, Christine ; Kidambi, Usha ; Van Riper, Gail ; Mccauley, Ermengilda ; Mumford, Richard A ; Lanza, Thomas J ; Lin, Linus S ; De Laszlo, Stephen E ; Young, David N ; Yang, Ginger ; Dean, Dennis C ; Raab, Conrad E ; Wallace, Mike A ; Jones, Allen N ; Hagmann, William K ; Schmidt, John A ; Pepinsky, R Blake ; Scott, Daniel M ; Lee, Wen-Cherng ; Cornebise, Mark A ; Detmers, Patricia A

The Journal of pharmacology and experimental therapeutics, September 2003, Vol.306(3), pp.903-13 [Peer Reviewed Journal]

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16
Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses
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Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses

Lin, Ko-Chung ; Ateeq, Humayun S. ; Hsiung, Sherry H. ; Chong, Lillian T. ; Zimmerman, Craig N. ; Castro, Alfredo ; Lee, Wen-Cherng ; Hammond, Charles E. ; Kalkunte, Sandhya ; Chen, Ling-Ling ; Pepinsky, R. Blake ; Leone, Diane R. ; Sprague, Andrew G. ; Abraham, William M. ; Gill, Alan ; Lobb, Roy R. ; Adams, Steven P.

Journal of Medicinal Chemistry, 03/1999, Vol.42(5), pp.920-934 [Peer Reviewed Journal]

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17
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Research Dataset
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CCDC 759847: Experimental Crystal Structure Determination

Ma, Bin ; Guckian, K.M. ; Lin, E.Y.-S. ; Lee, Wen-Cherng ; Scott, D. ; Kumaravel, G. ; Macdonald, T.L. ; Lynch, K.R. ; Black, C. ; Chollate, S. ; Hahm, Kyungmin ; Hetu, G. ; Jin, Ping ; Luo, Yi ; Rohde, E. ; Rossomando, A. ; Scannevin, R. ; Wang, J. ; Yang, Chunhua

2010

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18
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Duplexed, bead‐based competitive assay for inhibitors of protein kinases

Simons, Peter C. ; Young, Susan M. ; Gibaja, Veronica ; Lee, WenCherng ; Josiah, Serene ; Edwards, Bruce S. ; Sklar, Larry A.

Cytometry Part A, July 2007, Vol.71(7), pp.451-459 [Peer Reviewed Journal]

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19
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Article
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Duplexed, bead-based competitive assay for inhibitors of protein kinases

Simons, Peter C ; Young, Susan M ; Gibaja, Veronica ; Lee, Wen-Cherng ; Josiah, Serene ; Edwards, Bruce S ; Sklar, Larry A

Cytometry. Part A : the journal of the International Society for Analytical Cytology, July 2007, Vol.71(7), pp.451-9 [Peer Reviewed Journal]

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20
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A Kinase‐focused Compound Collection: Compilation and Screening Strategy

Sun, Dongyu ; Chuaqui, Claudio ; Deng, Zhan ; Bowes, Scott ; Chin, Donovan ; Singh, Juswinder ; Cullen, Patrick ; Hankins, Gretchen ; Lee, WenCherng ; Donnelly, Jason ; Friedman, Jessica ; Josiah, Serene

Chemical Biology & Drug Design, June 2006, Vol.67(6), pp.385-394 [Peer Reviewed Journal]

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21
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Intracellular TGF-β Receptor Blockade Abrogates Smad-Dependent Fibroblast Activation In Vitro and In Vivo

Ishida, Wataru ; Mori, Yasuji ; Lakos, Gabriella ; Sun, Lihong ; Shan, Feng ; Bowes, Scott ; Josiah, Serene ; Lee, Wen-Cherng ; Singh, Juswinder ; Ling, Leona E ; Varga, John

Journal of Investigative Dermatology, August 2006, Vol.126(8), pp.1733-1744 [Peer Reviewed Journal]

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22
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An orally active small molecule TGF-beta receptor I antagonist inhibits the growth of metastatic murine breast cancer

Rausch, Matthew P ; Hahn, Tobias ; Ramanathapuram, Lalitha ; Bradley-Dunlop, Deborah ; Mahadevan, Daruka ; Mercado-Pimentel, Melania E ; Runyan, Raymond B ; Besselsen, David G ; Zhang, Xiamei ; Cheung, H-Kam ; Lee, Wen-Cherng ; Ling, Leona E ; Akporiaye, Emmanuel T

Anticancer research, June 2009, Vol.29(6), pp.2099-109 [Peer Reviewed Journal]

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23
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Corrigendum to “Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)”: [Bioorg. Med. Chem. Lett. 13 (2003) 4355]

Singh, Juswinder ; Chuaqui, Claudio E ; Ann Boriack-Sjodin, P ; Lee, Wen-Cherng ; Pontz, Timothy ; Corbley, Michael J ; Cheung, H.-Kam ; Arduini, Robert M ; Mead, Jonathan N ; Newman, Miki N ; Papadatos, James L ; Bowes, Scott ; Josiah, Serene ; Ling, Leona E

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(11), pp.2991-2991 [Peer Reviewed Journal]

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24
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Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)

Singh, Juswinder ; Chuaqui, Claudio E ; Boriack-Sjodin, P.Ann ; Lee, Wen-Cherng ; Pontz, Timothy ; Corbley, Michael J ; Cheung, H.-Kam ; Arduini, Robert M ; Mead, Jonathan N ; Newman, Miki N ; Papadatos, James L ; Bowes, Scott ; Josiah, Serene ; Ling, Leona E

Bioorganic & Medicinal Chemistry Letters, 15 December 2003, Vol.13(24), pp.4355-4359 [Peer Reviewed Journal]

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25
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SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model

Fu, Kai ; Corbley, Michael J ; Sun, Lihong ; Friedman, Jessica E ; Shan, Feng ; Papadatos, James L ; Costa, Donald ; Lutterodt, Frank ; Sweigard, Harry ; Bowes, Scott ; Choi, Michael ; Boriack-Sjodin, P Ann ; Arduini, Robert M ; Sun, Dongyu ; Newman, Miki N ; Zhang, Xiamei ; Mead, Jonathan N ; Chuaqui, Claudio E ; Cheung, H-Kam ; Zhang, Xin ; Cornebise, Mark ; Carter, Mary Beth ; Josiah, Serene ; Singh, Juswinder ; Lee, Wen-Cherng ; Gill, Alan ; Ling, Leona E

Arteriosclerosis, thrombosis, and vascular biology, April 2008, Vol.28(4), pp.665-71 [Peer Reviewed Journal]

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