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10 Results  for Everything (Includes Articles)

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Overcoming mutagenicity and ion channel activity: optimization of selective spleen tyrosine kinase inhibitors

Ellis, J Michael ; Altman, Michael D ; Bass, Alan ; Butcher, John W ; Byford, Alan J ; Donofrio, Anthony ; Galloway, Sheila ; Haidle, Andrew M ; Jewell, James ; Kelly, Nancy ; Leccese, Erica K ; Lee, Sandra ; Maddess, Matthew ; Miller, J Richard ; Moy, Lily Y ; Osimboni, Ekundayo ; Otte, Ryan D ; Reddy, M Vijay ; Spencer, Kerrie ; Sun

Journal of medicinal chemistry, 26 February 2015, Vol.58(4), pp.1929-39 [Peer Reviewed Journal]

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Development and pharmacological validation of novel methods of B cell activation in rat whole blood

Shin, John ; Spatz, Marianne ; Brandish, Philip ; Gervais, Francois ; Zhang-Hoover, Jie ; Leccese, Erica ; Hicks, Alexandra

Journal of Pharmacological and Toxicological Methods, January 2015, Vol.71, pp.61-67 [Peer Reviewed Journal]

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Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Smith, Graham F ; Altman, Michael D ; Andresen, Brian ; Baker, James ; Brubaker, Jason D ; Chen, Hongmin ; Chen, Yiping ; Childers, Matthew ; Donofrio, Anthony ; Ferguson, Heidi ; Fischer, Christian ; Fischmann, Thierry O ; Gibeau, Craig ; Hicks, Alexander ; Jin, Sue ; Kattar, Sam ; Kleinschek, Melanie A ; Leccese, Erica ; Lesburg, Charles ; Li, Chaomin

Bioorganic & Medicinal Chemistry Letters, 15 June 2017, Vol.27(12), pp.2721-2726 [Peer Reviewed Journal]

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Development and optimization of a high-throughput micro-computed tomography imaging method incorporating a novel analysis technique to evaluate bone mineral density of arthritic joints in a rodent model of collagen induced arthritis

Sevilla, Raquel S ; Cruz, Francisco ; Chiu, Chi-Sung ; Xue, Dahai ; Bettano, Kimberly A ; Zhu, Joe ; Chakravarthy, Kalyan ; Faltus, Robert ; Wang, Shubing ; Vanko, Amy ; Robinson, Gain ; Zielstorff, Mark ; Miao, John ; Leccese, Erica ; Conway, Donald ; Moy, Lily Y ; Dogdas, Belma ; Cicmil, Milenko ; Zhang, Weisheng

Bone, April 2015, Vol.73, pp.32-41 [Peer Reviewed Journal]

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Discovery of 5-Amino- N -(1 H -pyrazol-4-yl)pyrazolo[1,5- a ]pyrimidine-3-carboxamide Inhibitors of IRAK4

Lim, Jongwon ; Altman, Michael D ; Baker, James ; Brubaker, Jason D ; Chen, Hongmin ; Chen, Yiping ; Fischmann, Thierry ; Gibeau, Craig ; Kleinschek, Melanie A ; Leccese, Erica ; Lesburg, Charles ; Maclean, John K. F ; Moy, Lily Y ; Mulrooney, Erin F ; Presland, Jeremy ; Rakhilina, Larissa ; Smith, Graham F ; Steinhuebel, Dietrich ; Yang, Ruojing Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

ACS Medicinal Chemistry Letters, 11 June 2015, Vol.6(6) [Peer Reviewed Journal]

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6
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Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis

Chakravarthy, Kalyan ; Faltus, Robert ; Robinson, Gain ; Sevilla, Raquel ; Shin, John ; Zielstorff, Mark ; Byford, Alan ; Leccese, Erica ; Caniga, Michael J ; Hseih, Suchun ; Zhang, Shuli ; Chiu, Chi-Sung ; Zhang-Hoover, Jie ; Moy, Lily Y ; Mcleod, Robbie L ; Stoffregen, Dana ; Zhang, Weisheng ; Murtaza, Anwar ; Cicmil, Milenko

BMC musculoskeletal disorders, 04 December 2014, Vol.15, pp.409 [Peer Reviewed Journal]

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Discovery of novel BTK inhibitors with carboxylic acids

Gao, Xiaolei ; Wang, James ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Selyutin, Oleg ; Yu, Wensheng ; Yu, Younong ; Anand, Rajan ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cai, Jiaqiang ; Cooper, Alan ; Zhu, Hugh ; Maloney, Kevin ; Gao, Ying-Duo ; Fischmann

Bioorganic & medicinal chemistry letters, 15 March 2017, Vol.27(6), pp.1471-1477 [Peer Reviewed Journal]

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Discovery of 3-morpholino-imidazole1,5-apyrazine BTK inhibitors for rheumatoid arthritis

Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Gao, Xiaolei ; Wang, James ; Yu, Younong ; Anand, Rajan ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cai, Jiaqiang ; Zhu, Hugh ; Desai, Jagdish ; Maloney, Kevin ; Gao, Ying-Duo ; Fischmann, Thierry O ; Presland, Jeremy ; Mansueto

Bioorganic & medicinal chemistry letters, 15 August 2017, Vol.27(16), pp.3939-3943 [Peer Reviewed Journal]

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9
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PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models

Ellwood-Yen, Katharine ; Keilhack, Heike ; Kunii, Kaiko ; Dolinski, Brian ; Connor, Yamicia ; Hu, Kun ; Nagashima, Kumiko ; O'Hare, Erin ; Erkul, Yusuf ; Di Bacco, Alessandra ; Gargano, Diana ; Shomer, Nirah H ; Angagaw, Minilik ; Leccese, Erica ; Andrade, Paula ; Hurd, Melissa ; Shin, Myung K ; Vogt, Thomas F ; Northrup

Cancer research, 15 April 2011, Vol.71(8), pp.3052-65 [Peer Reviewed Journal]

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Discovery of 8-Amino-imidazo[1,5- a ]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto ; Gao, Xiaolei ; Wang, James ; Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Yu, Younong ; Vaccaro, Henry ; Liu, Shilan ; Yang, Chundao ; Wu, Hao ; Cooper, Alan ; de Man, Jos ; Kaptein, Allard ; Maloney, Kevin ; Hornak, Viktor ; Gao, Ying-Duo ; Fischmann, Thierry O ; Raaijmakers, Hans ; Vu-Pham, Diep ; Presland, Jeremy ; Mansueto, My ; Xu, Zangwei ; Leccese, Erica ; Zhang-Hoover, Jie ; Knemeyer, Ian ; Garlisi, Charles G ; Bays, Nathan ; Stivers, Peter ; Brandish, Philip E ; Hicks, Alexandra ; Kim, Ronald ; Kozlowski, Joseph A Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

ACS Medicinal Chemistry Letters, 11 February 2016, Vol.7(2) [Peer Reviewed Journal]

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