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Reversed-polarity synthesis of diaryl ketones via palladium-catalyzed cross-coupling of acylsilanes

Schmink, Jason R ; Krska, Shane W

Journal of the American Chemical Society, 14 December 2011, Vol.133(49), pp.19574-7 [Peer Reviewed Journal]

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High-throughput optimization of Ir-catalyzed C-H borylation: a tutorial for practical applications

Preshlock, Sean M ; Ghaffari, Behnaz ; Maligres, Peter E ; Krska, Shane W ; Maleczka, Robert E ; Smith, Milton R

Journal of the American Chemical Society, 22 May 2013, Vol.135(20), pp.7572-82 [Peer Reviewed Journal]

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A soluble copper(I) source and stable salts of volatile ligands for copper-catalyzed C-X couplings

Maligres, Peter E ; Krska, Shane W ; Dormer, Peter G

The Journal of organic chemistry, 07 September 2012, Vol.77(17), pp.7646-51 [Peer Reviewed Journal]

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Silyl phosphorus and nitrogen donor chelates for homogeneous ortho borylation catalysis

Ghaffari, Behnaz ; Preshlock, Sean M ; Plattner, Donald L ; Staples, Richard J ; Maligres, Peter E ; Krska, Shane W ; Maleczka, Robert E ; Smith, Milton R

Journal of the American Chemical Society, 15 October 2014, Vol.136(41), pp.14345-8 [Peer Reviewed Journal]

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Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305)

Strotman, Neil A ; Baxter, Carl A ; Brands, Karel M J ; Cleator, Ed ; Krska, Shane W ; Reamer, Robert A ; Wallace, Debra J ; Wright, Timothy J

Journal of the American Chemical Society, 01 June 2011, Vol.133(21), pp.8362-71 [Peer Reviewed Journal]

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6
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Photoredox-Catalyzed Hydroxymethylation of Heteroaromatic Bases

Huff, Chelsea A ; Cohen, Ryan D ; Dykstra, Kevin D ; Streckfuss, Eric ; Dirocco, Daniel A ; Krska, Shane W

The Journal of organic chemistry, 19 August 2016, Vol.81(16), pp.6980-7 [Peer Reviewed Journal]

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7
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The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis

Krska, Shane W ; Dirocco, Daniel A ; Dreher, Spencer D ; Shevlin, Michael

Accounts of chemical research, 19 December 2017, Vol.50(12), pp.2976-2985 [Peer Reviewed Journal]

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8
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An approach to heterodiarylmethanes via sp2–sp3 Suzuki−Miyaura cross-coupling

Stewart, Gavin W ; Maligres, Peter E ; Baxter, Carl A ; Junker, Ellyn M ; Krska, Shane W ; Scott, Jeremy P

Tetrahedron, 30 June 2016, Vol.72(26), pp.3701-3706 [Peer Reviewed Journal]

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9
Synthesis and Hydrogenation Activity of Iron Dialkyl Complexes with Chiral Bidentate Phosphines
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Synthesis and Hydrogenation Activity of Iron Dialkyl Complexes with Chiral Bidentate Phosphines

Hoyt, Jordan M. ; Shevlin, Michael ; Margulieux, Grant W. ; Krska, Shane W. ; Tudge, Matthew T. ; Chirik, Paul J.

Organometallics, 10/27/2014, Vol.33(20), pp.5781-5790 [Peer Reviewed Journal]

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10
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Dynamic kinetic resolution: asymmetric transfer hydrogenation of alpha-alkyl-substituted beta-ketoamides

Limanto, John ; Krska, Shane W ; Dorner, Benjamin T ; Vazquez, Enrique ; Yoshikawa, Naoki ; Tan, Lushi

Organic letters, 05 February 2010, Vol.12(3), pp.512-5 [Peer Reviewed Journal]

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11
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Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst

Chang, Mingxin ; Huang, Yuhua ; Liu, Shaodong ; Chen, Yonggang ; Krska, Shane W. ; Davies, Ian W. ; Zhang, Xumu

Angewandte Chemie International Edition, 17 November 2014, Vol.53(47), pp.12761-12764 [Peer Reviewed Journal]

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12
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CO Cross‐Coupling of Activated Aryl and Heteroaryl Halides with Aliphatic Alcohols

Maligres, Peter E. ; Li, Jing ; Krska, Shane W. ; Schreier, John D. ; Raheem, Izzat T.

Angewandte Chemie International Edition, 03 September 2012, Vol.51(36), pp.9071-9074 [Peer Reviewed Journal]

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13
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Bismuth Acetate as a Catalyst for the Sequential Protodeboronation of Di- and Triborylated Indoles

Shen, Fangyi ; Tyagarajan, Sriram ; Perera, Damith ; Krska, Shane W ; Maligres, Peter E ; Smith, Milton R ; Maleczka, Robert E

Organic letters, 01 April 2016, Vol.18(7), pp.1554-7 [Peer Reviewed Journal]

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14
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Cu-mediated C–H 18F-fluorination of electron-rich (hetero)arenes

Mccammant, Matthew S ; Thompson, Stephen ; Brooks, Allen F ; Krska, Shane W ; Scott, Peter J. H ; Sanford, Melanie S Univ. of Michigan, Ann Arbor, Mi (United States) (Corporate Author)

Organic Letters, 30 June 2017, Vol.19(14) [Peer Reviewed Journal]

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15
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Synthesis of antifungal glucan synthase inhibitors from enfumafungin

Zhong, Yong-Li ; Gauthier, Donald R ; Shi, Yao-Jun ; Mclaughlin, Mark ; Chung, John Y L ; Dagneau, Philippe ; Marcune, Benjamin ; Krska, Shane W ; Ball, Richard G ; Reamer, Robert A ; Yasuda, Nobuyoshi

The Journal of organic chemistry, 06 April 2012, Vol.77(7), pp.3297-310 [Peer Reviewed Journal]

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16
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A Traceless Directing Group for CH Borylation

Preshlock, Sean M. ; Plattner, Donald L. ; Maligres, Peter E. ; Krska, Shane W. ; Maleczka, Robert E. ; Smith, Milton R.

Angewandte Chemie International Edition, 02 December 2013, Vol.52(49), pp.12915-12919 [Peer Reviewed Journal]

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17
Synthesis of Water-Soluble Carbosilane Dendrimers
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Synthesis of Water-Soluble Carbosilane Dendrimers

Krska, Shane W. ; Seyferth, Dietmar

Journal of the American Chemical Society, 04/1998, Vol.120(15), pp.3604-3612 [Peer Reviewed Journal]

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18
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Asymmetric hydrogenation of protected allylic amines

Steinhuebel, Dietrich P ; Krska, Shane W ; Alorati, Anthony ; Baxter, Jenny M ; Belyk, Kevin ; Bishop, Brian ; Palucki, Michael ; Sun, Yongkui ; Davies, Ian W

Organic letters, 17 September 2010, Vol.12(18), pp.4201-3 [Peer Reviewed Journal]

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19
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Enantioselective hydrogenation of alpha-aryloxy alpha,beta-unsaturated acids. Asymmetric synthesis of alpha-aryloxycarboxylic acids

Maligres, Peter E ; Krska, Shane W ; Humphrey, Guy R

Organic letters, 02 September 2004, Vol.6(18), pp.3147-50 [Peer Reviewed Journal]

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20
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The unusual role of CO transfer in molybdenum-catalyzed asymmetric alkylations

Krska, Shane W ; Hughes, David L ; Reamer, Robert A ; Mathre, David J ; Sun, Yongkui ; Trost, Barry M

Journal of the American Chemical Society, 30 October 2002, Vol.124(43), pp.12656-7 [Peer Reviewed Journal]

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21
Use of Steric Hindrance and a Metallacyclobutene Resting State to Develop Robust and Kinetically Characterizable Zirconium-Based Imine Metathesis Catalysts
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Use of Steric Hindrance and a Metallacyclobutene Resting State to Develop Robust and Kinetically Characterizable Zirconium-Based Imine Metathesis Catalysts

Krska, Shane W. ; Zuckerman, Rebecca L. ; Bergman, Robert G.

Journal of the American Chemical Society, 11/1998, Vol.120(45), pp.11828-11829 [Peer Reviewed Journal]

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22
Zirconium-Mediated Metathesis of Imines:  A Study of the Scope, Longevity, and Mechanism of a Complicated Catalytic System
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Zirconium-Mediated Metathesis of Imines:  A Study of the Scope, Longevity, and Mechanism of a Complicated Catalytic System

Zuckerman, Rebecca L. ; Krska, Shane W. ; Bergman, Robert G.

Journal of the American Chemical Society, 02/2000, Vol.122(5), pp.751-761 [Peer Reviewed Journal]

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23
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Unlocking the potential of asymmetric hydrogenation at Merck

Shultz, C Scott ; Krska, Shane W

Accounts of chemical research, December 2007, Vol.40(12), pp.1320-6 [Peer Reviewed Journal]

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24
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Heterocyclic Regioisomer Enumeration (HREMS): A Cheminformatics Design Tool

Tyagarajan, Sriram ; Lowden, Christopher T ; Peng, Zhengwei ; Dykstra, Kevin D ; Sherer, Edward C ; Krska, Shane W

Journal of chemical information and modeling, 22 June 2015, Vol.55(6), pp.1130-5 [Peer Reviewed Journal]

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25
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Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst

Chang, Mingxin ; Huang, Yuhua ; Liu, Shaodong ; Chen, Yonggang ; Krska, Shane W ; Davies, Ian W ; Zhang, Xumu

Angewandte Chemie, Nov 17, 2014, Vol.53(47), pp.12761-12764 [Peer Reviewed Journal]

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26
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CO Cross‐Coupling of Activated Aryl and Heteroaryl Halides with Aliphatic Alcohols

Maligres, Peter E. ; Li, Jing ; Krska, Shane W. ; Schreier, John D. ; Raheem, Izzat T.

Angewandte Chemie, 03 September 2012, Vol.124(36), pp.9205-9208 [Peer Reviewed Journal]

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27
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Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst

Chang, Mingxin ; Huang, Yuhua ; Liu, Shaodong ; Chen, Yonggang ; Krska, Shane W. ; Davies, Ian W. ; Zhang, Xumu

Angewandte Chemie, 17 November 2014, Vol.126(47), pp.12975-12978 [Peer Reviewed Journal]

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28
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Additional pitfalls of using 1,1‐ADEQUATE for structure elucidation

Cohen, Ryan D. ; Saurí, Josep ; Huff, Chelsea A. ; Krska, Shane W. ; Martin, Gary E.

Magnetic Resonance in Chemistry, November 2016, Vol.54(11), pp.897-900 [Peer Reviewed Journal]

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29
Anionic Cyclopolymerization of Linked Bis(vinylsilyl) Monomers:  Substituent Control over Polymer Structure
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Anionic Cyclopolymerization of Linked Bis(vinylsilyl) Monomers:  Substituent Control over Polymer Structure

Krska, Shane W. ; Ueno, Keiji ; Seyferth, Dietmar

Macromolecules, 01/1999, Vol.32(1), pp.1-9 [Peer Reviewed Journal]

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30
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Conclusive evidence for a retention-retention pathway for the molybdenum-catalyzed asymmetric alkylation

Lloyd-Jones, Guy C ; Krska, Shane W ; Hughes, David L ; Gouriou, Laure ; Bonnet, Veronique D ; Jack, Kevin ; Sun, Yongkui ; Reamer, Robert A

Journal of the American Chemical Society, 28 January 2004, Vol.126(3), pp.702-3 [Peer Reviewed Journal]

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31
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Synthesis of a tertiary carbinamide via a novel Rh-catalyzed asymmetric hydrogenation

Limanto, John ; Shultz, C Scott ; Dorner, Benjamin ; Desmond, Richard A ; Devine, Paul N ; Krska, Shane W

The Journal of organic chemistry, 15 February 2008, Vol.73(4), pp.1639-42 [Peer Reviewed Journal]

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32
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A Traceless Directing Group for CH Borylation

Preshlock, Sean M. ; Plattner, Donald L. ; Maligres, Peter E. ; Krska, Shane W. ; Maleczka, Robert E. ; Smith, Milton R.

Angewandte Chemie, 02 December 2013, Vol.125(49), pp.13153-13157 [Peer Reviewed Journal]

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33
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Site-selective 18F fluorination of unactivated C–H bonds mediated by a manganese porphyrin† †Electronic supplementary information (ESI) available: Detailed experimental procedures and spectroscopic data for all new compounds. See DOI: 10.1039/c7sc04545j

Liu, Wei ; Huang, Xiongyi ; Placzek, Michael S. ; Krska, Shane W. ; Mcquade, Paul ; Hooker, Jacob M. ; Groves, John T.

Liu, Wei, Xiongyi Huang, Michael S. Placzek, Shane W. Krska, Paul McQuade, Jacob M. Hooker, and John T. Groves. 2018. “Site-selective 18F fluorination of unactivated C–H bonds mediated by a manganese porphyrin† †Electronic supplementary information (ESI) available: Detailed experimental procedures and spectroscopic data for all new compounds. See DOI: 10.1039/c7sc04545j.” Chemical Science 9 (5): 1168-1172. doi:10.1039/c7sc04545j. http://dx.doi.org/10.1039/c7sc04545j. [Peer Reviewed Journal]

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34
Enabling Efficient Late-Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction-Driven Data Processing: Enabling Efficient Late-Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction-Driven Data Processing
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Enabling Efficient Late-Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction-Driven Data Processing: Enabling Efficient Late-Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction-Driven Data Processing

Yao, Huifang ; Liu, Yong ; Tyagarajan, Sriram ; Streckfuss, Eric ; Reibarkh, Mikhail ; Chen, Kuanchang ; Zamora, Ismael ; Fontaine, Fabien ; Goracci, Laura ; Helmy, Roy ; Bateman, Kevin P. ; Krska, Shane W.

European Journal of Organic Chemistry, 12/22/2017, Vol.2017(47), pp.7122-7126 [Peer Reviewed Journal]

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35
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Protecting group free radical C-H trifluoromethylation of peptides

Ichiishi, Naoko ; Caldwell, John P ; Lin, Melissa ; Zhong, Wendy ; Zhu, Xiaohong ; Streckfuss, Eric ; Kim, Hai-Young ; Parish, Craig A ; Krska, Shane W

Chemical science, 07 May 2018, Vol.9(17), pp.4168-4175 [Peer Reviewed Journal]

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36
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Cobalt precursors for high-throughput discovery of base metal asymmetric alkene hydrogenation catalysts

Friedfeld, Max R ; Shevlin, Michael ; Hoyt, Jordan M ; Krska, Shane W ; Tudge, Matthew T ; Chirik, Paul J

Science (New York, N.Y.), 29 November 2013, Vol.342(6162), pp.1076-80 [Peer Reviewed Journal]

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37
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Enantioselective synthesis of a chiral fluoropiperidine via asymmetric hydrogenation of a vinyl fluoride

Krska, Shane W ; Mitten, Jeffrey V ; Dormer, Peter G ; Mowrey, Dale ; Machrouhi, Fouzia ; Sun, Yongkui ; Nelson, Todd D

Tetrahedron, 2009, Vol.65(44), pp.8987-8994 [Peer Reviewed Journal]

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