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Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells

Xie, Jenny H ; Nomura, Naomi ; Koprak, Sam L ; Quackenbush, Elizabeth J ; Forrest, Michael J ; Rosen, Hugh

Journal of immunology (Baltimore, Md. : 1950), 01 April 2003, Vol.170(7), pp.3662-70 [Peer Reviewed Journal]

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Substitution of a single residue in Stichodactyla helianthus peptide, ShK-Dap22, reveals a novel pharmacological profile

Middleton, Richard E ; Sanchez, Manuel ; Linde, Ana-Rosa ; Bugianesi, Randal M ; Dai, Ge ; Felix, John P ; Koprak, Sam L ; Staruch, Mary Jo ; Bruguera, Marc ; Cox, Rachael ; Ghosh, Amrita ; Hwang, Jeremy ; Jones, Simmonette ; Kohler, Martin ; Slaughter, Robert S ; Mcmanus, Owen B ; Kaczorowski, Gregory J ; Garcia, Maria L

Biochemistry, 25 November 2003, Vol.42(46), pp.13698-707 [Peer Reviewed Journal]

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Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: Novel therapeutic agents for the treatment of metabolic syndrome

Gu, Xin ; Dragovic, Jasminka ; Koo, Gloria C ; Koprak, Sam L ; Legrand, Cheryl ; Mundt, Steven S ; Shah, Kashmira ; Springer, Marty S ; Tan, Eugene Y ; Thieringer, Rolf ; Hermanowski-Vosatka, Anne ; Zokian, Hratch J ; Balkovec, James M ; Waddell, Sherman T

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(23), pp.5266-5269 [Peer Reviewed Journal]

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Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720

Hale, Jeffrey J ; Neway, William ; Mills, Sander G ; Hajdu, Richard ; Ann Keohane, Carol ; Rosenbach, Mark ; Milligan, James ; Shei, Gan-Ju ; Chrebet, Gary ; Bergstrom, James ; Card, Deborah ; Koo, Gloria C ; Koprak, Sam L ; Jackson, Jesse J ; Rosen, Hugh ; Mandala, Suzanne

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(12), pp.3351-3355 [Peer Reviewed Journal]

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