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17 Results  for Everything (Includes Articles)

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CorrigendumCorrigendum to "The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists"[Bioorg. Med. Chem. Lett. 12 (2002) 611]

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Jr, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; de Laszlo, Stephen E ; Mccauley, Ermenegilda ; Van Riper, Gail ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(12), pp.1695-1695 [Peer Reviewed Journal]

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A novel one-pot synthesis of substituted 4-t-butyldimethylsilyloxy-thiazoles

Kopka, Ihor E.

Tetrahedron Letters, 1988, Vol.29(31), pp.3765-3768 [Peer Reviewed Journal]

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Selective semisynthetic modification of L-156,602, a novel cyclic hexadepsipeptide antibiotic

Kopka, Ihor E.

Tetrahedron Letters, 1990, Vol.31(33), pp.4711-4714 [Peer Reviewed Journal]

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4
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Synthesis and cannabinoid-1 receptor binding affinity of conformationally constrained analogs of taranabant

Kopka, Ihor E. ; Lin, Linus S. ; Jewell, James P. ; Lanza, Thomas J. ; Fong, Tung M. ; Shen, Chun-Pyn ; Lao, Zhege J. ; Ha, Sookhee ; Castonguay, Laurie G. ; Van Der Ploeg, Lex ; Goulet, Mark T. ; Hagmann, William K.

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(16), pp.4757-4761 [Peer Reviewed Journal]

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5
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A total synthesis of (±)-dihydropalustrine

Wasserman, Harry D. ; Leadbetter, Michael R. ; Kopka, Ihor E.

Tetrahedron Letters, 1984, Vol.25(22), pp.2391-2394 [Peer Reviewed Journal]

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6
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Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides containing extended alkyl residues At P 1'

Esser, Craig K. ; Kopka, Ihor E. ; Durette, Philippe L. ; Harrison, Richard K. ; Niedzwiecki, Lisa M. ; Izquierdo-Martin, Maria ; Stein, Ross L. ; Hagmann, William K.

Bioorganic & Medicinal Chemistry Letters, 1995, Vol.5(6), pp.539-542 [Peer Reviewed Journal]

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7
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N-(Arylacetyl)-biphenylalanines as Potent VLA-4 Antagonists

Li, Bing ; de Laszlo, Stephen E ; Kamenecka, Theodore M ; Kopka, Ihor E ; Durette, Philippe L ; Lanza, Jr, Thomas ; Maccoss, Malcolm ; Tong, Sharon ; Mumford, Richard A ; Mccauley, Ermengilda D ; Van Riper, Gail ; Schmidt, John A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(16), pp.2141-2144 [Peer Reviewed Journal]

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8
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Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow

Egger, Linda A ; Kidambi, Usha ; Cao, Jin ; Van Riper, Gail ; Mccauley, Ermengilda ; Mumford, Richard A ; Amo, Suzanne ; Lingham, Russell ; Lanza, Thomas ; Lin, Linus S ; De Laszlo, Stephen E ; Young, David N ; Kopka, Ihor E ; Tong, Sharon ; Pikounis, Bill ; Benson, Evelyn ; Warwood, Sarah ; Bargatze, Robert F ; Hagmann, William K ; Schmidt, John A ; Detmers, Patricia A

The Journal of pharmacology and experimental therapeutics, July 2002, Vol.302(1), pp.153-62 [Peer Reviewed Journal]

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Inhibition of matrix metalloproteinases by N-carboxyalkyl dipeptides: Enhanced potency and selectivity with substituted P 1′ homophenylalanines

Sahoo, Soumya P. ; Caldwell, Charles G. ; Chapman, Kevin T. ; Durette, Philippe L. ; Esser, Craig K. ; Kopka, Ihor E. ; Polo, Scott A. ; Sperow, Kelly M. ; Niedzwiecki, Lisa M. ; Izquierdo-Martin, Maria ; Chang, Benedict C. ; Harrison, Richard K. ; Stein, Ross L. ; Maccoss, Malcolm ; Hagmann, William K.

Bioorganic & Medicinal Chemistry Letters, 1995, Vol.5(20), pp.2441-2446 [Peer Reviewed Journal]

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Substituted N-(3,5-Dichlorobenzenesulfonyl)- l-prolyl-phenylalanine analogues as potent VLA-4 antagonists

Kopka, Ihor E ; Young, David N ; Lin, Linus S ; Mumford, Richard A ; Magriotis, Plato A ; Maccoss, Malcolm ; Mills, Sander G ; Riper, Gail Van ; Mccauley, Ermengilda ; Egger, Linda E ; Kidambi, Usha ; Schmidt, John A ; Lyons, Kathryn ; Stearns, Ralph ; Vincent, Stella ; Colletti, Adria ; Wang, Zhen ; Tong, Sharon ; Wang, Junying ; Zheng, Song ; Owens, Karen ; Levorse, Dorothy ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(4), pp.637-640 [Peer Reviewed Journal]

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The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

Lin, Linus S. ; Kopka, Ihor E. ; Mumford, Richard A. ; Magriotis, Plato A. ; Lanza, Thomas ; Durette, Philippe L. ; Kamenecka, Theodore ; Young, David N. ; Laszlo, Stephen E.de ; Mccauley, Ermenegilda ; Riper, Gail Van ; Kidambi, Usha ; Egger, Linda A. ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A. ; Maccoss, Malcolm ; Hagmann, William K.

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(4), pp.611-614 [Peer Reviewed Journal]

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12
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Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

Kopka, Ihor E ; Lin, Linus S ; Mumford, Richard A ; Lanza, Thomas ; Magriotis, Plato A ; Young, David ; Delaszlo, Stephen E ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Lyons, Kathryn ; Vincent, Stella ; Egger, Linda A ; Kidambi, Usha ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Tong, Sharon ; Owens, Karen ; Levorse, Dorothy ; Schmidt, John A ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(17), pp.2415-2418 [Peer Reviewed Journal]

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13
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Substituted 2-aminopyridines as inhibitors of nitric oxide synthases

Hagmann, William K ; Caldwell, Charles G ; Chen, Ping ; Durette, Philippe L ; Esser, Craig K ; Lanza, Thomas J ; Kopka, Ihor E ; Guthikonda, Ravi ; Shah, Shrenik K ; Maccoss, Malcolm ; Chabin, Renee M ; Fletcher, Daniel ; Grant, Stephan K ; Green, Barbara G ; Humes, John L ; Kelly, Theresa M ; Luell, Sylvie ; Meurer, Roger ; Moore, Vernon ; Pacholok, Stephen G ; Pavia, Tony ; Williams, Hollis R ; Wong, Kenny K

Bioorganic & Medicinal Chemistry Letters, 2000, Vol.10(17), pp.1975-1978 [Peer Reviewed Journal]

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14
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The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

Hagmann, William K ; Durette, Philippe L ; Lanza, Thomas ; Kevin, Nancy Jo ; de Laszlo, Stephen E ; Kopka, Ihor E ; Young, David ; Magriotis, Plato A ; Li, Bing ; Lin, Linus S ; Yang, Ginger ; Kamenecka, Theodore ; Chang, Linda L ; Wilson, Jonathan ; Maccoss, Malcolm ; Mills, Sander G ; Van Riper, Gail ; Mccauley, Ermengilda ; Egger, Linda A ; Kidambi, Usha ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Johannes ; Tong, Sharon ; Fenyk-Melody, Judy ; Owens, Karen ; Levorse, Dorothy ; Kim, Philip ; Schmidt, John A ; Mumford, Richard A

Bioorganic & Medicinal Chemistry Letters, 2001, Vol.11(20), pp.2709-2713 [Peer Reviewed Journal]

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15
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The inhibition of C5a receptor binding by analogs of L-156,602, a cyclic hexadepsipeptide antibiotic

Durette, Philippe L. ; Kopka, Ihor E. ; Lanza, Thomas J. ; Goulet, Joung L. ; Kinneary, Joanne F. ; Caldwell, Charles G. ; Hammond, Milton L. ; Bondy, Steven S. ; Zambias, Robert A. ; Boger, Joshua ; Rollins, Thomas ; Siciliano, Salvatore ; Cianciarulo, Dana N. ; Kobayashi, Sumire V. ; Springer, Martin S. ; Hagmann, William K.

Bioorganic & Medicinal Chemistry Letters, 1992, Vol.2(9), pp.1033-1038 [Peer Reviewed Journal]

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16
Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides
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Inhibition of Stromelysin-1 (MMP-3) by P 1 ‘-Biphenylylethyl Carboxyalkyl Dipeptides

Esser, Craig K. ; Bugianesi, Robert L. ; Caldwell, Charles G. ; Chapman, Kevin T. ; Durette, Philippe L. ; Girotra, Narindar N. ; Kopka, Ihor E. ; Lanza, Thomas J. ; Levorse, Dorothy A. ; Maccoss, Malcolm ; Owens, Karen A. ; Ponpipom, Mitree M. ; Simeone, Joseph P. ; Harrison, Richard K. ; Niedzwiecki, Lisa ; Becker, Joseph W. ; Marcy, Alice I. ; Axel, Melinda G. ; Christen, Amy J. ; Mcdonnell, Joseph ; Moore, Vernon L. ; Olszewski, Julie M. ; Saphos, Cheryl ; Visco, Denise M. ; Shen, Frank ; Colletti, Adria ; Krieter, Philip A. ; Hagmann, William K.

Journal of Medicinal Chemistry, 03/1997, Vol.40(6), pp.1026-1040 [Peer Reviewed Journal]

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17
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The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists

Lin, Linus S ; Kopka, Ihor E ; Mumford, Richard A ; Magriotis, Plato A ; Lanza, Thomas ; Durette, Philippe L ; Kamenecka, Theodore ; Young, David N ; De Laszlo, Stephen E ; Mccauley, Ermenegilda ; Riper, Gail Van ; Kidambi, Usha ; Egger, Linda A ; Tong, Xinchun ; Lyons, Kathryn ; Vincent, Stella ; Stearns, Ralph ; Colletti, Adria ; Teffera, Yohannes ; Fenyk-Melody, Judy ; Schmidt, John A ; Maccoss, Malcolm ; Hagmann, William K

Bioorganic & medicinal chemistry letters, 25 February 2002, Vol.12(4), pp.611-4 [Peer Reviewed Journal]

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