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The role of the conserved Lys68*:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: Multiple forced covariant amino acid substitutions in natural variants

Deu, Edgar ; Koch, Keith A. ; Kirsch, Jack F.

Protein Science, May 2002, Vol.11(5), pp.1062-1073 [Peer Reviewed Journal]

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A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

Monovich, Lauren ; Vega, Richard B ; Meredith, Erik ; Miranda, Karl ; Rao, Chang ; Capparelli, Michael ; Lemon, Douglas D ; Phan, Dillon ; Koch, Keith A ; Chapo, Joseph A ; Hood, David B ; Mckinsey, Timothy A

FEBS Letters, 05 February 2010, Vol.584(3), pp.631-637 [Peer Reviewed Journal]

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

Liles, John T ; Corkey, Britton K ; Notte, Gregory T ; Budas, Grant R ; Lansdon, Eric B ; Hinojosa-Kirschenbaum, Ford ; Badal, Shawn S ; Lee, Michael ; Schultz, Brian E ; Wise, Sarah ; Pendem, Swetha ; Graupe, Michael ; Castonguay, Laurie ; Koch, Keith A ; Wong, Melanie H ; Papalia, Giuseppe A ; French, Dorothy M ; Sullivan, Theodore ; Huntzicker, Erik G ; Ma, Frank Y ; Nikolic-Paterson, David J ; Altuhaifi, Tareq ; Yang, Haichun ; Fogo, Agnes B ; Breckenridge, David G

The Journal of clinical investigation, 01 October 2018, Vol.128(10), pp.4485-4500 [Peer Reviewed Journal]

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The role of Midkine in Children with Dilated Cardiomyopathy

Jiang, Xuan ; Woulfe, Kathleen ; Karimpour-Fard, Anis ; Koch, Keith ; Stauffer, Brian ; Miyamoto, Shelley ; Sucharov, Carmen

Journal of Molecular and Cellular Cardiology, November 2017, Vol.112, pp.143-144 [Peer Reviewed Journal]

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Identification of potent and selective amidobipyridyl inhibitors of protein kinase D

Meredith, Erik L ; Beattie, Kimberly ; Burgis, Robin ; Capparelli, Michael ; Chapo, Joseph ; Dipietro, Lucian ; Gamber, Gabriel ; Enyedy, Istvan ; Hood, David B ; Hosagrahara, Vinayak ; Jewell, Charles ; Koch, Keith A ; Lee, Wendy ; Lemon, Douglas D ; Mckinsey, Timothy A ; Miranda, Karl ; Pagratis, Nikos ; Phan, Dillon ; Plato, Craig ; Rao, Chang ; Rozhitskaya, Olga ; Soldermann, Nicolas ; Springer, Clayton ; Van Eis, Maurice ; Vega, Richard B ; Yan, Wanlin ; Zhu, Qingming ; Monovich, Lauren G

Journal of medicinal chemistry, 12 August 2010, Vol.53(15), pp.5422-38 [Peer Reviewed Journal]

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tRNA-Guanine Transglycosylase from Escherichia coli: Overexpression, Purification and Quaternary Structure

Garcia, George A ; Koch, Keith A ; Chong, Shaorong

Journal of Molecular Biology, 1993, Vol.231(2), pp.489-497 [Peer Reviewed Journal]

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The Candida glabrata Amt1 copper‐sensing transcription factor requires Swi/Snf and Gcn5 at a critical step in copper detoxification

Koch, Keith A. ; Allard, Stéphane ; Santoro, Nicholas ; Côté, Jacques ; Thiele, Dennis J.

Molecular Microbiology, June 2001, Vol.40(5), pp.1165-1174 [Peer Reviewed Journal]

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Screening and Identification of a Novel Class of TGF-β Type 1 Receptor Kinase Inhibitor

Huynh, Q. Khai ; Wise, Sarah J ; Koch, Keith A ; Castonguay, Laurie A ; Reid, Brian G ; Pagratis, Erinn E ; Koditek, David ; Glascock, Christopher B ; Pitts, Kelly R ; Turner, Benjamin A ; Liu, Xiaohong ; Hung, Magdeleine ; Han, Bin ; Pagratis, Nikos

Journal of Biomolecular Screening, August 2011, Vol.16(7), pp.724-733 [Peer Reviewed Journal]

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3,5-Diarylazoles as novel and selective inhibitors of protein kinase D

Gamber, Gabriel G ; Meredith, Erik ; Zhu, Qingming ; Yan, Wanlin ; Rao, Chang ; Capparelli, Michael ; Burgis, Robin ; Enyedy, Istvan ; Zhang, Ji-Hu ; Soldermann, Nicolas ; Beattie, Kimberley ; Rozhitskaya, Olga ; Koch, Keith A ; Pagratis, Nikos ; Hosagrahara, Vinayak ; Vega, Richard B ; Mckinsey, Timothy A ; Monovich, Lauren

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(5), pp.1447-1451 [Peer Reviewed Journal]

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Identification of orally available naphthyridine protein kinase D inhibitors

Meredith, Erik L ; Ardayfio, Ophelia ; Beattie, Kimberly ; Dobler, Markus R ; Enyedy, Istvan ; Gaul, Christoph ; Hosagrahara, Vinayak ; Jewell, Charles ; Koch, Keith ; Lee, Wendy ; Lehmann, Hansjoerg ; Mckinsey, Timothy A ; Miranda, Karl ; Pagratis, Nikos ; Pancost, Margaret ; Patnaik, Anup ; Phan, Dillon ; Plato, Craig ; Qian, Ming ; Rajaraman, Vasumathy ; Rao, Chang ; Rozhitskaya, Olga ; Ruppen, Thomas ; Shi, Jie ; Siska, Sarah J ; Springer, Clayton ; Van Eis, Maurice ; Vega, Richard B ; Von Matt, Anette ; Yang, Lihua ; Yoon, Taeyoung ; Zhang, Ji-Hu ; Zhu, Na ; Monovich, Lauren G

Journal of medicinal chemistry, 12 August 2010, Vol.53(15), pp.5400-21 [Peer Reviewed Journal]

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Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae
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Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae

Peña, Maria Marjorette O. ; Koch, Keith A. ; Thiele, Dennis J.

Molecular and Cellular Biology, 05/01/1998, Vol.18(5), pp.2514-2523 [Peer Reviewed Journal]

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A trans -Activation Domain in Yeast Heat Shock Transcription Factor Is Essential for Cell Cycle Progression during Stress
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A trans -Activation Domain in Yeast Heat Shock Transcription Factor Is Essential for Cell Cycle Progression during Stress

Morano, Kevin A. ; Santoro, Nicholas ; Koch, Keith A. ; Thiele, Dennis J.

Molecular and Cellular Biology, 01/01/1999, Vol.19(1), pp.402-411 [Peer Reviewed Journal]

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The human cDNA for a homologue of the plant enzyme 1-aminocyclopropane-1-carboxylate synthase encodes a protein lacking that activity

Koch, Keith A ; Capitani, Guido ; Gruetter, Markus G ; Kirsch, Jack F

Gene, 11 July 2001, Vol.272(1-2), pp.75-84 [Peer Reviewed Journal]

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Transcriptional regulation and function of yeast metallothioneins

Zhou, Pengbo ; Koch, Keith A ; Thiele, Dennis J

Journal of Inorganic Biochemistry, July 1993, Vol.51(1-2), pp.578-578 [Peer Reviewed Journal]

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Sphingolipid biosynthesis in pathogenic fungi: Identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus

Fornarotto, Michelle ; Xiao, Li ; Hou, Yan ; Koch, Keith A ; Chang, Edcon ; O'Malley, Robert M ; Black, Todd A ; Cable, Michael B ; Walker, Scott S

BBA - Molecular and Cell Biology of Lipids, 2006, Vol.1761(1), pp.52-63 [Peer Reviewed Journal]

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Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1

Monovich, Lauren ; Koch, Keith A ; Burgis, Robin ; Osimboni, Ekundayo ; Mann, Thierry ; Wall, Daniel ; Gao, Jinhai ; Feng, Yan ; Vega, Richard B ; Turner, Benjamin A ; Hood, David B ; Law, Andy ; Papst, Philip J ; Koditek, David ; Chapo, Joseph A ; Reid, Brian G ; Melvin, Lawrence S ; Pagratis, Nikos C ; Mckinsey, Timothy A

BBA - Gene Regulatory Mechanisms, 2009, Vol.1789(5), pp.422-431 [Peer Reviewed Journal]

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G Scale on the move

Koch, Keith

Model Railroader, Feb 2003, Vol.70(2), pp.102-105

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