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11 Results  for Everything (Includes Articles)

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How Communication Among Members of the Health Care Team Affects Maternal Morbidity and Mortality

Brennan, Rita Allen ; Keohane, Carol Ann

Journal of Obstetric, Gynecologic & Neonatal Nursing, November 2016, Vol.45(6), pp.878-884 [Peer Reviewed Journal]

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Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistance

Nawrocki, Andrea R ; Rodriguez, Carlos G ; Toolan, Dawn M ; Price, Olga ; Henry, Melanie ; Forrest, Gail ; Szeto, Daphne ; Keohane, Carol Ann ; Pan, Yie ; Smith, Karen M ; Raheem, Izzat T ; Cox, Christopher D ; Hwa, Joyce ; Renger, John J ; Smith, Sean M

Diabetes, January 2014, Vol.63(1), pp.300-11 [Peer Reviewed Journal]

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Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720

Allende, Maria L ; Sasaki, Teiji ; Kawai, Hiromichi ; Olivera, Ana ; Mi, Yide ; Van Echten-Deckert, Gerhild ; Hajdu, Richard ; Rosenbach, Mark ; Keohane, Carol Ann ; Mandala, Suzanne ; Spiegel, Sarah ; Proia, Richard L

The Journal of biological chemistry, 10 December 2004, Vol.279(50), pp.52487-92 [Peer Reviewed Journal]

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A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists

Hale, Jeffrey J ; Lynch, Christopher L ; Neway, William ; Mills, Sander G ; Hajdu, Richard ; Keohane, Carol Ann ; Rosenbach, Mark J ; Milligan, James A ; Shei, Gan-Ju ; Parent, Stephen A ; Chrebet, Gary ; Bergstrom, James ; Card, Deborah ; Ferrer, Marc ; Hodder, Peter ; Strulovici, Berta ; Rosen, Hugh ; Mandala, Suzanne

Journal of medicinal chemistry, 30 December 2004, Vol.47(27), pp.6662-5 [Peer Reviewed Journal]

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Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3

Li, Zhen ; Chen, Weirong ; Hale, Jeffrey J ; Lynch, Christopher L ; Mills, Sander G ; Hajdu, Richard ; Keohane, Carol Ann ; Rosenbach, Mark J ; Milligan, James A ; Shei, Gan-Ju ; Chrebet, Gary ; Parent, Stephen A ; Bergstrom, James ; Card, Deborah ; Forrest, Michael ; Quackenbush, Elizabeth J ; Wickham, L Alexandra ; Vargas, Hugo ; Evans, Rose M ; Rosen

Journal of medicinal chemistry, 06 October 2005, Vol.48(20), pp.6169-73 [Peer Reviewed Journal]

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2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists

Colandrea, Vincent J ; Legiec, Irene E ; Huo, Pei ; Yan, Lin ; Hale, Jeffrey J ; Mills, Sander G ; Bergstrom, James ; Card, Deborah ; Chebret, Gary ; Hajdu, Richard ; Keohane, Carol Ann ; Milligan, James A ; Rosenbach, Mark J ; Shei, Gan-Ju ; Mandala, Suzanne M

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(11), pp.2905-2908 [Peer Reviewed Journal]

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Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists

Hale, Jeffrey J ; Doherty, George ; Toth, Leslie ; Mills, Sander G ; Hajdu, Richard ; Keohane, Carol Ann ; Rosenbach, Mark ; Milligan, James ; Shei, Gan-Ju ; Chrebet, Gary ; Bergstrom, James ; Card, Deborah ; Forrest, Michael ; Sun, Shu-Yu ; West, Sarah ; Xie, Huijuan ; Nomura, Naomi ; Rosen, Hugh ; Mandala, Suzanne

Bioorganic & medicinal chemistry letters, 05 July 2004, Vol.14(13), pp.3501-5 [Peer Reviewed Journal]

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Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors

Yan, Lin ; Hale, Jeffrey J ; Lynch, Christopher L ; Budhu, Richard ; Gentry, Amy ; Mills, Sander G ; Hajdu, Richard ; Keohane, Carol Ann ; Rosenbach, Mark J ; Milligan, James A ; Shei, Gan-Ju ; Chrebet, Gary ; Bergstrom, James ; Card, Deborah ; Rosen, Hugh ; Mandala, Suzanne M

Bioorganic & medicinal chemistry letters, 04 October 2004, Vol.14(19), pp.4861-6 [Peer Reviewed Journal]

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Design and synthesis of conformationally constrained 3-( N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors

Yan, Lin ; Hale, Jeffrey J ; Lynch, Christopher L ; Budhu, Richard ; Gentry, Amy ; Mills, Sander G ; Hajdu, Richard ; Keohane, Carol Ann ; Rosenbach, Mark J ; Milligan, James A ; Shei, Gan-Ju ; Chrebet, Gary ; Bergstrom, James ; Card, Deborah ; Rosen, Hugh ; Mandala, Suzanne M

Bioorganic & Medicinal Chemistry Letters, 2004, Vol.14(19), pp.4861-4866 [Peer Reviewed Journal]

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The pharmacokinetics of a thiazole benzenesulfonamide beta 3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: improving oral bioavailability

Stearns, Ralph A ; Miller, Randy R ; Tang, Wei ; Kwei, Gloria Y ; Tang, Frank S ; Mathvink, Robert J ; Naylor, Elizabeth M ; Chitty, Dawn ; Colandrea, Vincent J ; Weber, Ann E ; Colletti, Adria E ; Strauss, John R ; Keohane, Carol Ann ; Feeney, William P ; Iliff, Susan A ; Chiu, Shuet-Hing Lee

Drug metabolism and disposition: the biological fate of chemicals, July 2002, Vol.30(7), pp.771-7 [Peer Reviewed Journal]

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Identification of metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma

Hop, Cornelis E C A ; Wang, Yanfeng ; Kumar, Sanjeev ; Elipe, Maria Victoria Silva ; Raab, Conrad E ; Dean, Dennis C ; Poon, Grace K ; Keohane, Carol-Ann ; Strauss, John ; Chiu, Shuet-Hing L ; Curtis, Neil ; Elliott, Jason ; Gerhard, Ute ; Locker, Karen ; Morrison, Denise ; Mortishire-Smith, Russell ; Thomas, Steven ; Watt, Alan P ; Evans, David C

Drug metabolism and disposition: the biological fate of chemicals, August 2002, Vol.30(8), pp.937-43 [Peer Reviewed Journal]

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