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1
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Development of a fast screening and confirmatory method by liquid chromatography-quadrupole-time-of-flight mass spectrometry for glucuronide-conjugated methyltestosterone metabolite in tilapia

Amarasinghe, Kande ; Chu, Pak-Sin ; Evans, Eric ; Reimschuessel, Renate ; Hasbrouck, Nicholas ; Jayasuriya, Hiranthi

Journal of agricultural and food chemistry, 23 May 2012, Vol.60(20), pp.5084-8 [Peer Reviewed Journal]

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Tentative Structural Assignment of a Glucuronide Metabolite of Methyltestosterone in Tilapia Bile by Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

Nishshanka, Upul ; Chu, Pak-Sin ; Evans, Eric ; Reimschuessel, Renate ; Hasbrouck, Nicholas ; Amarasinghe, Kande ; Jayasuriya, Hiranthi

Journal of agricultural and food chemistry, 24 June 2015, Vol.63(24), pp.5753-60 [Peer Reviewed Journal]

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Application of time-of-flight mass spectrometry for screening of crude glycerins for toxic phorbol ester contaminants

Herath, Kithsiri ; Girard, Lauren ; Reimschuessel, Renate ; Jayasuriya, Hiranthi

Journal of Chromatography B, 01 March 2017, Vol.1046, pp.226-234 [Peer Reviewed Journal]

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4
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Structure of homoplatensimide A: a potential key biosynthetic intermediate of platensimycin isolated from Streptomyces platensis

Jayasuriya, Hiranthi ; Herath, Kithsiri B ; Ondeyka, John G ; Zink, Deborah L ; Burgess, Bruce ; Wang, Jun ; Singh, Sheo B

Tetrahedron Letters, 2008, Vol.49(22), pp.3648-3651 [Peer Reviewed Journal]

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5
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Screening for toxic phorbol esters in jerky pet treat products using LC–MS

Nishshanka, Upul ; Jayasuriya, Hiranthi ; Chattopadhaya, Chaitali ; Kijak, Philip J ; Chu, Pak-Sin ; Reimschuessel, Renate ; Tkachenko, Andriy ; Ceric, Olgica ; De Alwis, Hemakanthi G

Journal of Chromatography B, 01 May 2016, Vol.1020, pp.90-95 [Peer Reviewed Journal]

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6
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Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Wang, Jun ; Soisson, Stephen M ; Young, Katherine ; Shoop, Wesley ; Kodali, Srinivas ; Galgoci, Andrew ; Painter, Ronald ; Parthasarathy, Gopalakrishnan ; Tang, Yui S ; Cummings, Richard ; Ha, Sookhee ; Dorso, Karen ; Motyl, Mary ; Jayasuriya, Hiranthi ; Ondeyka, John ; Herath, Kithsiri ; Zhang, Chaowei ; Hernandez, Lorraine ; Allocco, John ; Basilio, Angela ; Tormo, José R ; Genilloud, Olga ; Vicente, Francisca ; Pelaez, Fernando ; Colwell, Lawrence ; Lee, Sang Ho ; Michael, Bruce ; Felcetto, Thomas ; Gill, Charles ; Silver, Lynn L ; Hermes, Jeffery D ; Bartizal, Ken ; Barrett, John ; Schmatz, Dennis ; Becker, Joseph W ; Cully, Doris ; Singh, Sheo B

Nature, 18 May 2006, Vol.441(7091), pp.358-61 [Peer Reviewed Journal]

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7
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Aspercyclide A–C, three novel fungal metabolites from Aspergillus sp. as inhibitors of high-affinity IgE receptor

Singh, Sheo B ; Jayasuriya, Hiranthi ; Zink, Deborah L ; Polishook, Jon D ; Dombrowski, Anne W ; Zweerink, Hans

Tetrahedron Letters, 2004, Vol.45(41), pp.7605-7608 [Peer Reviewed Journal]

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Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy

Singh, Sheo B ; Jayasuriya, Hiranthi ; Ondeyka, John G ; Herath, Kithsiri B ; Zhang, Chaowei ; Zink, Deborah L ; Tsou, Nancy N ; Ball, Richard G ; Basilio, Angela ; Genilloud, Olga ; Diez, Maria Teresa ; Vicente, Francisca ; Pelaez, Fernando ; Young, Katherine ; Wang, Jun

Journal of the American Chemical Society, 13 September 2006, Vol.128(36), pp.11916-20 [Peer Reviewed Journal]

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9
Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy [ J. Am. Chem. Soc. 2006 , 128 , 11916−11920].
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Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy [ J. Am. Chem. Soc. 2006 , 128 , 11916−11920].

Singh, Sheo B. ; Jayasuriya, Hiranthi ; Ondeyka, John G. ; Herath, Kithsiri B. ; Zhang, Chaowei ; Zink, Deborah L. ; Tsou, Nancy N. ; Ball, Richard G. ; Basilio, Angela ; Genilloud, Olga ; Diez, Maria Teresa ; Vicente, Francisca ; Pelaez, Fernando ; Young, Katherine ; Wang, Jun

Journal of the American Chemical Society, 12/2006, Vol.128(48), pp.15547-15547 [Peer Reviewed Journal]

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Isolation, enzyme-bound structure, and activity of platensimycin A 1 from Streptomyces platensis

Singh, Sheo B ; Jayasuriya, Hiranthi ; Herath, Kithsiri B ; Zhang, Chaowei ; Ondeyka, John G ; Zink, Deborah L ; Ha, Sookhee ; Parthasarathy, Gopalakrishnan ; Becker, Joseph W ; Wang, Jun ; Soisson, Stephen M

Tetrahedron Letters, 2009, Vol.50(37), pp.5182-5185 [Peer Reviewed Journal]

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11
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Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

Wang, Jun ; Galgoci, Andrew ; Kodali, Srinivas ; Herath, Kithsiri B ; Jayasuriya, Hiranthi ; Dorso, Karen ; Vicente, Francisca ; González, Antonio ; Cully, Doris ; Bramhill, David ; Singh, Sheo

The Journal of biological chemistry, 07 November 2003, Vol.278(45), pp.44424-8 [Peer Reviewed Journal]

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12
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Isolation, structure elucidation, and antibacterial activity of methiosetin, a tetramic acid from a tropical sooty mold (Capnodium sp.)

Herath, Kithsiri ; Jayasuriya, Hiranthi ; Zink, Deborah L ; Sigmund, Jan ; Vicente, Francisca ; De La Cruz, Mercedes ; Basilio, Angela ; Bills, Gerald F ; Polishook, Jon D ; Donald, Robert ; Phillips, John ; Goetz, Michael ; Singh, Sheo B

Journal of natural products, 23 March 2012, Vol.75(3), pp.420-4 [Peer Reviewed Journal]

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13
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Platensimycin and platencin congeners from Streptomyces platensis

Zhang, Chaowei ; Ondeyka, John ; Herath, Kithsiri ; Jayasuriya, Hiranthi ; Guan, Ziqiang ; Zink, Deborah L ; Dietrich, Lisa ; Burgess, Bruce ; Ha, Sookhee N ; Wang, Jun ; Singh, Sheo B

Journal of natural products, 25 March 2011, Vol.74(3), pp.329-40 [Peer Reviewed Journal]

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14
Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis
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Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis

Herath, Kithsiri B. ; Zhang, Chaowei ; Jayasuriya, Hiranthi ; Ondeyka, John G. ; Zink, Deborah L. ; Burgess, Bruce ; Wang, Jun ; Singh, Sheo B.

Organic Letters, 05/07/2009, Vol.11(9), pp.2043-2043 [Peer Reviewed Journal]

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15
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Selective and controlled hydrolysis of chloropeptin I. HIV-1 integrase activity of fragments

Singh, Sheo B ; Jayasuriya, Hiranthi ; Hazuda, Daria L ; Felock, Peter ; Homnick, Carl F ; Sardana, Mohinder ; Patane, Michael A

Tetrahedron Letters, 1998, Vol.39(48), pp.8769-8770 [Peer Reviewed Journal]

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16
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Structure and semisynthesis of platensimide A, produced by Streptomyces platensis

Herath, Kithsiri B ; Zhang, Chaowei ; Jayasuriya, Hiranthi ; Ondeyka, John G ; Zink, Deborah L ; Burgess, Bruce ; Wang, Jun ; Singh, Sheo B

Organic letters, 01 May 2008, Vol.10(9), pp.1699-702 [Peer Reviewed Journal]

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17
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Complestatin to chloropeptin I via a quantitative acid catalyzed rearrangement. Absolute stereochemical determination of complestatin

Jayasuriya, Hiranthi ; Salituro, Gino M ; Smith, Scott K ; Heck, James V ; Gould, Steven J ; Singh, Sheo B ; Homnick, Carl F ; Holloway, M.Katharine ; Pitzenberger, Steven M ; Patane, Michael A

Tetrahedron Letters, 1998, Vol.39(16), pp.2247-2248 [Peer Reviewed Journal]

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18
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Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Wang, Jun ; Kodali, Srinivas ; Lee, Sang Ho ; Galgoci, Andrew ; Painter, Ronald ; Dorso, Karen ; Racine, Fred ; Motyl, Mary ; Hernandez, Lorraine ; Tinney, Elizabeth ; Colletti, Steven L ; Herath, Kithsiri ; Cummings, Richard ; Salazar, Oscar ; González, Ignacio ; Basilio, Angela ; Vicente, Francisca ; Genilloud, Olga ; Pelaez, Fernando ; Jayasuriya, Hiranthi ; Young, Katherine ; Cully, Doris F ; Singh, Sheo B

Proceedings of the National Academy of Sciences of the United States of America, 01 May 2007, Vol.104(18), pp.7612-6 [Peer Reviewed Journal]

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19
Structure and Stereochemistry of Rediocide A, A Highly Modified Daphnane from Trigonostemon reidioides Exhibiting Potent Insecticidal Activity
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Structure and Stereochemistry of Rediocide A, A Highly Modified Daphnane from Trigonostemon reidioides Exhibiting Potent Insecticidal Activity

Jayasuriya, Hiranthi ; Zink, Deborah L. ; Singh, Suresh B. ; Borris, Robert P. ; Nanakorn, Weerachai ; Beck, Hans T. ; Balick, Michael J. ; Goetz, Michael A. ; Slayton, Lyndia ; Gregory, Lynn ; Zakson-Aiken, Michelle ; Shoop, Wesley ; Singh, Sheo B.

Journal of the American Chemical Society, 05/2000, Vol.122(20), pp.4998-4999 [Peer Reviewed Journal]

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20
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Efficient syntheses, human and yeast farnesyl-protein transferase inhibitory activities of chaetomellic acids and analogues

Singh, Sheo B ; Jayasuriya, Hiranthi ; Silverman, Keith C ; Bonfiglio, Cynthia A ; Williamson, Joanne M ; Lingham, Russell B

Bioorganic & Medicinal Chemistry, March 2000, Vol.8(3), pp.571-580 [Peer Reviewed Journal]

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21
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Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp

Herath, Kithsiri ; Harris, Guy ; Jayasuriya, Hiranthi ; Zink, Deborah ; Smith, Scott ; Vicente, Francisca ; Bills, Gerald ; Collado, Javier ; González, Antonio ; Jiang, Bo ; Kahn, Jennifer Nielsen ; Galuska, Stefan ; Giacobbe, Robert ; Abruzzo, George ; Hickey, Emily ; Liberator, Paul ; Xu, Deming ; Roemer, Terry ; Singh, Sheo B

Bioorganic & Medicinal Chemistry, 2009, Vol.17(3), pp.1361-1369 [Peer Reviewed Journal]

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22
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Isolation, enzyme-bound structure and antibacterial activity of platencin A 1 from Streptomyces platensis

Singh, Sheo B ; Ondeyka, John G ; Herath, Kithsiri B ; Zhang, Chaowei ; Jayasuriya, Hiranthi ; Zink, Deborah L ; Parthasarathy, Gopalakrishnan ; Becker, Joseph W ; Wang, Jun ; Soisson, Stephen M

Bioorganic & Medicinal Chemistry Letters, 2009, Vol.19(16), pp.4756-4759 [Peer Reviewed Journal]

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23
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Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad‐Spectrum Antibiotic Activity

Jayasuriya, Hiranthi ; Herath, Kithsiri B. ; Zhang, Chaowei ; Zink, Deborah L. ; Basilio, Angela ; Genilloud, Olga ; Diez, Maria Teresa ; Vicente, Francisca ; Gonzalez, Ignacio ; Salazar, Oscar ; Pelaez, Fernando ; Cummings, Richard ; Ha, Sookhee ; Wang, Jun ; Singh, Sheo B.

Angewandte Chemie International Edition, 18 June 2007, Vol.46(25), pp.4684-4688 [Peer Reviewed Journal]

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24
Clavaric Acid and Steroidal Analogues as Ras- and FPP-Directed Inhibitors of Human Farnesyl-Protein Transferase
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Clavaric Acid and Steroidal Analogues as Ras- and FPP-Directed Inhibitors of Human Farnesyl-Protein Transferase

Lingham, Russell B. ; Silverman, Keith C. ; Jayasuriya, Hiranthi ; Kim, B. Moon ; Amo, Suzanne E. ; Wilson, Francine R. ; Rew, Deborah J. ; Schaber, Michael D. ; Bergstrom, James D. ; Koblan, Kenneth S. ; Graham, Samuel L. ; Kohl, Nancy E. ; Gibbs, Jackson B. ; Singh, Sheo B.

Journal of Medicinal Chemistry, 11/1998, Vol.41(23), pp.4492-4501 [Peer Reviewed Journal]

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25
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Discovery of FabH/FabF inhibitors from natural products

Young, Katherine ; Jayasuriya, Hiranthi ; Ondeyka, John G ; Herath, Kithsiri ; Zhang, Chaowei ; Kodali, Srinivas ; Galgoci, Andrew ; Painter, Ronald ; Brown-Driver, Vickie ; Yamamoto, Robert ; Silver, Lynn L ; Zheng, Yingcong ; Ventura, Judith I ; Sigmund, Janet ; Ha, Sookhee ; Basilio, Angela ; Vicente, Francisca ; Tormo, José Rubén ; Pelaez, Fernando ; Youngman, Phil ; Cully, Doris ; Barrett, John F ; Schmatz, Dennis ; Singh, Sheo B ; Wang, Jun

Antimicrobial agents and chemotherapy, February 2006, Vol.50(2), pp.519-26 [Peer Reviewed Journal]

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26
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Isolation, structure, and HIV-1 integrase inhibitory activity of Cytosporic acid, a fungal metabolite produced by a Cytospora sp

Jayasuriya, Hiranthi ; Guan, Ziqiang ; Polishook, Jon D ; Dombrowski, Anne W ; Felock, Peter J ; Hazuda, Daria J ; Singh, Sheo B

Journal of natural products, April 2003, Vol.66(4), pp.551-3 [Peer Reviewed Journal]

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27
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Isolation, structure, absolute stereochemistry, and HIV-1 integrase inhibitory activity of integrasone, a novel fungal polyketide

Herath, Kithsiri B ; Jayasuriya, Hiranthi ; Bills, Gerald F ; Polishook, Jon D ; Dombrowski, Anne W ; Guan, Ziqiang ; Felock, Peter J ; Hazuda, Daria J ; Singh, Sheo B

Journal of natural products, May 2004, Vol.67(5), pp.872-4 [Peer Reviewed Journal]

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28
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Rediocides B-E, potent insecticides from Trigonostemon reidioides

Jayasuriya, Hiranthi ; Zink, Deborah L ; Borris, Robert P ; Nanakorn, Weerachai ; Beck, Hans T ; Balick, Michael J ; Goetz, Michael A ; Gregory, Lynn ; Shoop, Wesley L ; Singh, Sheo B

Journal of natural products, February 2004, Vol.67(2), pp.228-31 [Peer Reviewed Journal]

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29
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Thiazomycins, thiazolyl peptide antibiotics from Amycolatopsis fastidiosa

Zhang, Chaowei ; Herath, Kithsiri ; Jayasuriya, Hiranthi ; Ondeyka, John G ; Zink, Deborah L ; Occi, James ; Birdsall, Gwyneth ; Venugopal, Jayashree ; Ushio, Misti ; Burgess, Bruce ; Masurekar, Prakash ; Barrett, John F ; Singh, Sheo B

Journal of natural products, 22 May 2009, Vol.72(5), pp.841-7 [Peer Reviewed Journal]

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30
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Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents

Herath, Kithsiri B ; Jayasuriya, Hiranthi ; Guan, Ziqiang ; Schulman, Marvin ; Ruby, Carolyn ; Sharma, Neelam ; Macnaul, Karen ; Menke, John G ; Kodali, Srinivas ; Galgoci, Andrew ; Wang, Jun ; Singh, Sheo B

Journal of natural products, September 2005, Vol.68(9), pp.1437-40 [Peer Reviewed Journal]

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31
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Nodulisporic acids D-F: structure, biological activities, and biogenetic relationships

Singh, Sheo B ; Ondeyka, John G ; Jayasuriya, Hiranthi ; Zink, Deborah L ; Ha, Sookhee N ; Dahl-Roshak, Arlene ; Greene, Joyce ; Kim, Jennifer A ; Smith, Mchardy M ; Shoop, Wesley ; Tkacz, Jan S

Journal of natural products, September 2004, Vol.67(9), pp.1496-506 [Peer Reviewed Journal]

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32
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Isolation and structure of antagonists of chemokine receptor (CCR5)

Jayasuriya, Hiranthi ; Herath, Kithsiri B ; Ondeyka, John G ; Polishook, Jon D ; Bills, Gerald F ; Dombrowski, Anne W ; Springer, Marty S ; Siciliano, Sal ; Malkowitz, Lorraine ; Sanchez, Manuel ; Guan, Ziqiang ; Tiwari, Suroojnauth ; Stevenson, Dennis W ; Borris, Robert P ; Singh, Sheo B

Journal of natural products, June 2004, Vol.67(6), pp.1036-8 [Peer Reviewed Journal]

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33
The Complestatins as HIV-1 Integrase Inhibitors. Efficient Isolation, Structure Elucidation, and Inhibitory Activities of Isocomplestatin, Chloropeptin I, New Complestatins, A and B, and Acid-Hydrolysis Products of Chloropeptin I
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The Complestatins as HIV-1 Integrase Inhibitors. Efficient Isolation, Structure Elucidation, and Inhibitory Activities of Isocomplestatin, Chloropeptin I, New Complestatins, A and B, and Acid-Hydrolysis Products of Chloropeptin I

Singh, Sheo B. ; Jayasuriya, Hiranthi ; Salituro, Gino M. ; Zink, Deborah L. ; Shafiee, Ali ; Heimbuch, Brian ; Silverman, Keith C. ; Lingham, Russell B. ; Genilloud, Olga ; Teran, Ana ; Vilella, Dolores ; Felock, Peter ; Hazuda, Daria

Journal of Natural Products, 07/2001, Vol.64(7), pp.874-882 [Peer Reviewed Journal]

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34
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Durhamycin A, a potent inhibitor of HIV Tat transactivation

Jayasuriya, Hiranthi ; Lingham, Russell B ; Graham, Pia ; Quamina, Donette ; Herranz, Lucia ; Genilloud, Olga ; Gagliardi, Magda ; Danzeisen, Renee ; Tomassini, Joanne E ; Zink, Deborah L ; Guan, Ziqiang ; Singh, Sheo B

Journal of natural products, August 2002, Vol.65(8), pp.1091-5 [Peer Reviewed Journal]

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35
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Oreganic Acid, a Potent Inhibitor of Ras Farnesyl-Protein Transferase

Silverman, Keith C ; Jayasuriya, Hiranthi ; Cascales, Carmen ; Vilella, Dolores ; Bills, Gerald F ; Jenkins, Rosalind G ; Singh, Sheo B ; Lingham, Russell B

Biochemical and Biophysical Research Communications, 17 March 1997, Vol.232(2), pp.478-481 [Peer Reviewed Journal]

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36
Clavaric Acid:  A Triterpenoid Inhibitor of Farnesyl-Protein Transferase from Clavariadelphus t runcatus
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Clavaric Acid:  A Triterpenoid Inhibitor of Farnesyl-Protein Transferase from Clavariadelphus t runcatus

Jayasuriya, Hiranthi ; Silverman, Keith C. ; Zink, Deborah L. ; Jenkins, Rosalind G. ; Sanchez, Manuel ; Pelaez, Fernando ; Vilella, Dolores ; Lingham, Russell B. ; Singh, Sheo B.

Journal of Natural Products, 12/1998, Vol.61(12), pp.1568-1570 [Peer Reviewed Journal]

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