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Mice harboring the human R138X loss-of-function mutation have increased insulin secretory capacity

Kleiner, Sandra ; Gomez, Daniel ; Megra, Bezawit ; Na, Erqian ; Bhavsar, Ramandeep ; Cavino, Katie ; Xin, Yurong ; Rojas, Jose ; Dominguez-Gutierrez, Giselle ; Zambrowicz, Brian ; Carrat, Gaelle ; Chabosseau, Pauline ; Hu, Ming ; Murphy, Andrew J ; Yancopoulos, George D ; Rutter, Guy A ; Gromada, Jesper

Proceedings of the National Academy of Sciences of the United States of America, 07 August 2018, Vol.115(32), pp.E7642-E7649 [Peer Reviewed Journal]

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Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells *

Dominguez, Veronica ; Raimondi, Claudio ; Somanath, Sangeeta ; Bugliani, Marco ; Loder, Merewyn K ; Edling, Charlotte E ; Divecha, Nullin ; Da Silva-Xavier, Gabriela ; Marselli, Lorella ; Persaud, Shanta J ; Turner, Mark D ; Rutter, Guy A ; Marchetti, Piero ; Falasca, Marco ; Maffucci, Tania

The Journal of Biological Chemistry, 2011, Vol.286(6), p.4216-4225 [Peer Reviewed Journal]

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Metabolome Response to Glucose in the β-Cell Line INS-1 832/13 *

Lorenz, Matthew A ; El Azzouny, Mahmoud A ; Kennedy, Robert T ; Burant, Charles F

The Journal of Biological Chemistry, 2013, Vol.288(15), p.10923-10935 [Peer Reviewed Journal]

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Islet β cell mass in diabetes and how it relates to function, birth, and death

Weir, Gordon C. ; Bonner‐Weir, Susan

Annals of the New York Academy of Sciences, April 2013, Vol.12811(1), pp.92-105 [Peer Reviewed Journal]

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Role of pancreatic‐derived factor in type 2 diabetes: evidence from pancreatic β cells and liver

Wang, Chunjiong ; Burkhardt, Brant R ; Guan, Youfei ; Yang, Jichun

Nutrition Reviews, February 2012, Vol.70(2), pp.100-106 [Peer Reviewed Journal]

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Within-class differences of the sulfonylureas should be accounted for. Reply to Schrijnders D, Kleefstra N and Landman GWD [letter]

Levy, Jonathan ; Riefflin, Axel ; Holman, Rury

Diabetologia, 2015, Vol.58(6), pp.1376-1377 [Peer Reviewed Journal]

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Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets

Dai, C. ; Brissova, M. ; Hang, Y. ; Thompson, C. ; Poffenberger, G. ; Shostak, A. ; Chen, Z. ; Stein, R. ; Powers, A.

Diabetologia, 2012, Vol.55(3), pp.707-718 [Peer Reviewed Journal]

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Imaging Insulin Secretion from Mouse Pancreas by MRI Is Improved by Use of a Zinc-Responsive MRI Sensor with Lower Affinity for Zn Ions

Martins, André F ; Clavijo Jordan, Veronica ; Bochner, Filip ; Chirayil, Sara ; Paranawithana, Namini ; Zhang, Shanrong ; Lo, Su-Tang ; Wen, Xiaodong ; Zhao, Piyu ; Neeman, Michal ; Sherry, A Dean

Journal of the American Chemical Society, 19 December 2018, Vol.140(50), pp.17456-17464 [Peer Reviewed Journal]

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Impaired β-cell function in the adult offspring of rats fed a protein-restricted diet during lactation is associated with changes in muscarinic acetylcholine receptor subtypes

De Oliveira, Júlio C ; Miranda, Rosiane A ; Barella, Luiz F ; Torrezan, Rosana ; Agostinho, Aryane R ; Ribeiro, Tatiane A. S ; Franco, Claudinéia C. S ; Malta, Ananda ; Tófolo, Laize P ; Gravena, Clarice ; Mathias, Paulo C. F

British Journal of Nutrition, 2014, Vol.111(2), pp.227-235 [Peer Reviewed Journal]

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The changing face of diabetes in youth: lessons learned from studies of type 2 diabetes

Hannon, Tamara S. ; Arslanian, Silva A.

Annals of the New York Academy of Sciences, September 2015, Vol.13531(1), pp.113-137 [Peer Reviewed Journal]

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Nucleo-cytosolic Shuttling of FoxO1 Directly Regulates Mouse Ins2 but Not Ins1 Gene Expression in Pancreatic Beta Cells (MIN6) *

Meur, Gargi ; Qian, Qingwen ; Da Silva Xavier, Gabriela ; Pullen, Timothy J ; Tsuboi, Takashi ; Mckinnon, Caroline ; Fletcher, Laura ; Tavaré, Jeremy M ; Hughes, Stephen ; Johnson, Paul ; Rutter, Guy A

The Journal of Biological Chemistry, 2011, Vol.286(15), p.13647-13656 [Peer Reviewed Journal]

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12
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Human Mutation within Per-Arnt-Sim (PAS) Domain-containing Protein Kinase (PASK) Causes Basal Insulin Hypersecretion *

Semplici, Francesca ; Vaxillaire, Martine ; Fogarty, Sarah ; Semache, Meriem ; Bonnefond, Amélie ; Fontés, Ghislaine ; Philippe, Julien ; Meur, Gargi ; Diraison, Frederique ; Sessions, Richard B ; Rutter, Jared ; Poitout, Vincent ; Froguel, Philippe ; Rutter, Guy A

The Journal of Biological Chemistry, 2011, Vol.286(51), p.44005-44014 [Peer Reviewed Journal]

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Protein restriction in early life is associated with changes in insulin sensitivity and pancreatic β-cell function during pregnancy

Ignácio-souza, Letícia Martins ; Reis, Sílvia Regina ; Arantes, Vanessa Cristina ; Botosso, Bárbara Laet ; Veloso, Roberto Vilela ; Ferreira, Fabiano ; Boschero, Antonio Carlos ; Carneiro, Everardo Magalhães ; De Barros Reis, Marise Auxiliadora ; Latorraca, Márcia Queiroz

British Journal of Nutrition, 2012, Vol.109(2), pp.236-247 [Peer Reviewed Journal]

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The increase in serum 25-hydroxyvitamin D following weight loss does not contribute to the improvement in insulin sensitivity, insulin secretion and β-cell function

Thibault, Véronique ; Morisset, Anne-Sophie ; Brown, Christine ; Carpentier, André C ; Baillargeon, Jean-Patrice ; Langlois, Marie-France ; Gagnon, Claudia

British Journal of Nutrition, 2015, Vol.114(2), pp.161-168 [Peer Reviewed Journal]

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Vitamin D supplementation has no effect on insulin sensitivity or secretion in vitamin D–deficient, overweight or obese adults: a randomized placebo-controlled trial

Mousa, Aya ; Naderpoor, Negar ; De Courten, Maximilian Pj ; Teede, Helena ; Kellow, Nicole ; Walker, Karen ; Scragg, Robert ; De Courten, Barbora

The American Journal of Clinical Nutrition, 2017, Vol. 105(6), pp.1372-1381 [Peer Reviewed Journal]

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16
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Flushing Response Modifies the Association of Alcohol Consumption with Markers of Glucose Metabolism in Japanese Men and Women

Kuwahara, Keisuke ; Kochi, Takeshi ; Nanri, Akiko ; Tsuruoka, Hiroko ; Kurotani, Kayo ; Pham, Ngoc Minh ; Akter, Shamima ; Kabe, Isamu ; Mizoue, Tetsuya

Alcoholism: Clinical and Experimental Research, April 2014, Vol.38(4), pp.1042-1048 [Peer Reviewed Journal]

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17
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Alcohol Intake Interacts with CDKAL1, HHEX, and OAS3 Genetic Variants, Associated with the Risk of Type 2 Diabetes by Lowering Insulin Secretion in Korean Adults

Park, Sunmin ; Liu, Meiling ; Kang, Suna

Alcoholism: Clinical and Experimental Research, December 2018, Vol.42(12), pp.2326-2336 [Peer Reviewed Journal]

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18
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mTORC2 Signaling: A Path for Pancreatic β Cell's Growth and Function

Yuan, Ting ; Lupse, Blaz ; Maedler, Kathrin ; Ardestani, Amin

Journal of Molecular Biology, 30 March 2018, Vol.430(7), pp.904-918 [Peer Reviewed Journal]

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19
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Glycogen metabolism in the glucose‐sensing and supply‐driven β‐cell

Andersson, Lotta E. ; Nicholas, Lisa M. ; Filipsson, Karin ; Sun, Jiangming ; Medina, Anya ; Al‐Majdoub, Mahmoud ; Fex, Malin ; Mulder, Hindrik ; Spégel, Peter

FEBS Letters, December 2016, Vol.590(23), pp.4242-4251 [Peer Reviewed Journal]

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20
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The microtubule associated protein syntabulin is required for glucose-stimulated and cAMP-potentiated insulin secretion

Ying, Ying ; Li, Lingyun ; Cao, Wen ; Yan, Dan ; Zeng, Qing ; Kong, Xiangchen ; Lu, Lina ; Yan, Meng ; Xu, Xiaohui ; Qu, Junle ; Su, Qingning ; Ma, Xiaosong

FEBS Letters, 19 October 2012, Vol.586(20), pp.3674-3680 [Peer Reviewed Journal]

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21
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Loss of mPer2 increases plasma insulin levels by enhanced glucose-stimulated insulin secretion and impaired insulin clearance in mice

Zhao, Yue ; Zhang, Ying ; Zhou, Mengyi ; Wang, Shiming ; Hua, Zichun ; Zhang, Jianfa

FEBS Letters, 07 May 2012, Vol.586(9), pp.1306-1311 [Peer Reviewed Journal]

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22
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Regulation of insulin secretion: role of mitochondrial signalling

Jitrapakdee, S. ; Wutthisathapornchai, A. ; Wallace, J. ; MacDonald, M.

Diabetologia, 2010, Vol.53(6), pp.1019-1032 [Peer Reviewed Journal]

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23
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Insulin-dependent glucose metabolism in dairy cows with variable fat mobilization around calving

Weber, C ; Schäff, C.T ; Kautzsch, U ; Börner, S ; Erdmann, S ; Görs, S ; Röntgen, M ; Sauerwein, H ; Bruckmaier, R.M ; Metges, C.C ; Kuhla, B ; Hammon, H.M

Journal of Dairy Science, August 2016, Vol.99(8), pp.6665-6679 [Peer Reviewed Journal]

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24
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Peroxisome proliferator-activated receptor α (PPARα) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism

Frigerio, F. ; Brun, T. ; Bartley, C. ; Usardi, A. ; Bosco, D. ; Ravnskjær, K. ; Mandrup, S. ; Maechler, P.

Diabetologia, 2010, Vol.53(2), pp.331-340 [Peer Reviewed Journal]

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25
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Distinct and opposing roles for the phosphatidylinositol 3-OH kinase catalytic subunits p110α and p110β in the regulation of insulin secretion from rodent and human beta cells

Kolic, J. ; Spigelman, A. ; Plummer, G. ; Leung, E. ; Hajmrle, C. ; Kin, T. ; Shapiro, A. ; Manning Fox, J. ; MacDonald, P.

Diabetologia, 2013, Vol.56(6), pp.1339-1349 [Peer Reviewed Journal]

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26
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Postprandial whole-body glycolysis is similar in insulin-resistant and insulin-sensitive non-diabetic humans

Galgani, J. ; Ravussin, E.

Diabetologia, 2012, Vol.55(3), pp.737-742 [Peer Reviewed Journal]

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27
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Genetic evidence of the programming of beta cell mass and function by glucocorticoids in mice

Valtat, B. ; Dupuis, C. ; Zenaty, D. ; Singh-Estivalet, A. ; Tronche, F. ; Bréant, B. ; Blondeau, B.

Diabetologia, 2011, Vol.54(2), pp.350-359 [Peer Reviewed Journal]

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28
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Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

Aguayo-Mazzucato, C. ; Koh, A. ; Khattabi, I. ; Li, W.-C. ; Toschi, E. ; Jermendy, A. ; Juhl, K. ; Mao, K. ; Weir, G. ; Sharma, A. ; Bonner-Weir, S.

Diabetologia, 2011, Vol.54(3), pp.583-593 [Peer Reviewed Journal]

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29
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Impact of impaired insulin secretion and insulin resistance on the incidence of diabetes in a Japanese cohort. Reply to Yamauchi K and Aizawa T [letter]

Morimoto, Akiko ; Tatsumi, Yukako ; Deura, Kijyo ; Miyamatsu, Naomi ; Noda, Mitsuhiko ; Watanabe, Shaw

Diabetologia, 2013, Vol.56(11), pp.2546-2547 [Peer Reviewed Journal]

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30
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Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin

Asahara, S. ; Shibutani, Y. ; Teruyama, K. ; Inoue, H. ; Kawada, Y. ; Etoh, H. ; Matsuda, T. ; Kimura-Koyanagi, M. ; Hashimoto, N. ; Sakahara, M. ; Fujimoto, W. ; Takahashi, H. ; Ueda, S. ; Hosooka, T. ; Satoh, T. ; Inoue, H. ; Matsumoto, M. ; Aiba, A. ; Kasuga, M. ; Kido, Y.

Diabetologia, 2013, Vol.56(5), pp.1088-1097 [Peer Reviewed Journal]

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31
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VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells

Veluthakal, Rajakrishnan ; Tunduguru, Ragadeepthi ; Arora, Daleep ; Sidarala, Vaibhav ; Syeda, Khadija ; Vlaar, Cornelis ; Thurmond, Debbie ; Kowluru, Anjaneyulu

Diabetologia, 2015, Vol.58(11), pp.2573-2581 [Peer Reviewed Journal]

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32
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Variable effects of statins on glucose homeostasis parameters and their diabetogenic role

Kostapanos, Michael ; Agouridis, Aris ; Elisaf, Moses

Diabetologia, 2015, Vol.58(8), pp.1960-1961 [Peer Reviewed Journal]

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33
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Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice

Meier, Daniel ; Morcos, Mary ; Samarasekera, Thanya ; Zraika, Sakeneh ; Hull, Rebecca ; Kahn, Steven

Diabetologia, 2014, Vol.57(9), pp.1884-1888 [Peer Reviewed Journal]

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34
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Islet encapsulation: advances and obstacles

Weir, G.

Diabetologia, 2013, Vol.56(7), pp.1458-1461 [Peer Reviewed Journal]

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35
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The Ia-2β intronic miRNA, miR-153, is a negative regulator of insulin and dopamine secretion through its effect on the Cacna1c gene in mice

Xu, Huanyu ; Abuhatzira, Liron ; Carmona, Gilberto ; Vadrevu, Suryakiran ; Satin, Leslie ; Notkins, Abner

Diabetologia, 2015, Vol.58(10), pp.2298-2306 [Peer Reviewed Journal]

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36
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Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

Xiong, Xiwen ; Wang, Gaihong ; Tao, Rongya ; Wu, Pengfei ; Kono, Tatsuyoshi ; Li, Kevin ; Ding, Wen-Xing ; Tong, Xin ; Tersey, Sarah ; Harris, Robert ; Mirmira, Raghavendra ; Evans-Molina, Carmella ; Dong, X.

Diabetologia, 2016, Vol.59(1), pp.151-160 [Peer Reviewed Journal]

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37
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Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents

Christensen, Gitte ; Jacobsen, Maria ; Wendt, Anna ; Mollet, Ines ; Friberg, Josefine ; Frederiksen, Klaus ; Meyer, Michael ; Bruun, Christine ; Eliasson, Lena ; Billestrup, Nils

Diabetologia, 2015, Vol.58(6), pp.1282-1290 [Peer Reviewed Journal]

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38
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Variable effects of statins on glucose homeostasis parameters and their diabetogenic role. Reply to Kostapanos MS, Agouridis AP and Elisaf MS [letter]

Cederberg, Henna ; Laakso, Markku

Diabetologia, 2015, Vol.58(8), pp.1962-1963 [Peer Reviewed Journal]

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39
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Systemic inhibition of nitric oxide synthesis in non-diabetic individuals produces a significant deterioration in glucose tolerance by increasing insulin clearance and inhibiting insulin secretion

Natali, A. ; Ribeiro, R. ; Baldi, S. ; Tulipani, A. ; Rossi, M. ; Venturi, E. ; Mari, A. ; Macedo, M. ; Ferrannini, E.

Diabetologia, 2013, Vol.56(5), pp.1183-1191 [Peer Reviewed Journal]

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40
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Pharmacological inhibition of Eph receptors enhances glucose-stimulated insulin secretion from mouse and human pancreatic islets

Jain, R. ; Jain, D. ; Liu, Q. ; Bartosinska, B. ; Wang, J. ; Schumann, D. ; Kauschke, S. ; Eickelmann, P. ; Piemonti, L. ; Gray, N. ; Lammert, E.

Diabetologia, 2013, Vol.56(6), pp.1350-1355 [Peer Reviewed Journal]

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41
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Effect of exposure to non‐esterified fatty acid on progressive deterioration of insulin secretion in patients with Type 2 diabetes: a long‐term follow‐up study

Morita, S. ; Shimajiri, Y. ; Sakagashira, S. ; Furuta, M. ; Sanke, T.

Diabetic Medicine, August 2012, Vol.29(8), pp.980-985 [Peer Reviewed Journal]

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