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1
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Syntaxin-4 mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose-stimulated insulin secretion in human pancreatic beta cells

Xie, Li ; Zhu, Dan ; Dolai, Subhankar ; Liang, Tao ; Qin, Tairan ; Kang, Youhou ; Xie, Huanli ; Huang, Ya-Chi ; Gaisano, Herbert

Diabetologia, 2015, Vol.58(6), pp.1250-1259 [Peer Reviewed Journal]

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Acute intravenous glucose load impairs early insulin secretion and insulin content in islet β cells in mice

Yan, Dien ; Zhao, Yinan ; Gao, Xiuying ; Zhou, Yingsheng

Life Sciences, 01 January 2016, Vol.144, pp.148-155 [Peer Reviewed Journal]

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Article
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Changes in beta cell function occur in prediabetes and early disease in the Lepr db mouse model of diabetes

Do, Oanh ; Gunton, Jenny ; Gaisano, Herbert ; Thorn, Peter

Diabetologia, 2016, Vol.59(6), pp.1222-1230 [Peer Reviewed Journal]

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Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells

Zhu, Dan ; Xie, Li ; Karimian, Negar ; Liang, Tao ; Kang, Youhou ; Huang, Ya-Chi ; Gaisano, Herbert Y

Molecular Metabolism, May 2015, Vol.4(5), pp.418-426 [Peer Reviewed Journal]

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Bidirectional Insulin Granule Turnover in the Submembrane Space During K+ Depolarization‐Induced Secretion

Hatlapatka, Kathrin ; Matz, Magnus ; Schumacher, Kirstin ; Baumann, Knut ; Rustenbeck, Ingo

Traffic, September 2011, Vol.12(9), pp.1166-1178 [Peer Reviewed Journal]

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Are we overestimating the loss of beta cells in type 2 diabetes?

Marselli, Lorella ; Suleiman, Mara ; Masini, Matilde ; Campani, Daniela ; Bugliani, Marco ; Syed, Farooq ; Martino, Luisa ; Focosi, Daniele ; Scatena, Fabrizio ; Olimpico, Francesco ; Filipponi, Franco ; Masiello, Pellegrino ; Boggi, Ugo ; Marchetti, Piero

Diabetologia, 2014, Vol.57(2), pp.362-365 [Peer Reviewed Journal]

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7
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Article
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RalA GTPase Tethers Insulin Granules to L‐ and R‐Type Calcium Channels Through Binding α 2 δ‐1 Subunit

Xie, Li ; Kang, Youhou ; Liang, Tao ; Dolai, Subhankar ; Xie, Huanli ; Parsaud, Leon ; Lopez, Jamie A. ; He, Yu ; Chidambaram, Subbulakshmi ; Lam, Patrick P. ; James, David E. ; Sugita, Shuzo ; Gaisano, Herbert Y.

Traffic, April 2013, Vol.14(4), pp.428-439 [Peer Reviewed Journal]

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Article
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Amplification of insulin secretion by acetylcholine or phorbol ester is independent of β-cell microfilaments and distinct from metabolic amplification

Mourad, Nizar I ; Nenquin, Myriam ; Henquin, Jean-Claude

Molecular and Cellular Endocrinology, 10 March 2013, Vol.367(1-2), pp.11-20 [Peer Reviewed Journal]

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9
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Article
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Ultrastructural alterations of pancreatic beta cells in human diabetes mellitus

Masini, Matilde ; Martino, Luisa ; Marselli, Lorella ; Bugliani, Marco ; Boggi, Ugo ; Filipponi, Franco ; Marchetti, Piero ; De Tata, Vincenzo

Diabetes/Metabolism Research and Reviews, September 2017, Vol.33(6), pp.n/a-n/a [Peer Reviewed Journal]

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10
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Article
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The BECN1-BCL2 complex regulates insulin secretion and storage in mice

Kuramoto, Kenta ; He, Congcong

Autophagy, 02 November 2018, Vol.14(11), pp.2026-2028 [Peer Reviewed Journal]

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11
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Article
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Granule Mobility, Fusion Frequency and Insulin Secretion Are Differentially Affected by Insulinotropic Stimuli

Schumacher, Kirstin ; Matz, Magnus ; Brüning, Dennis ; Baumann, Knut ; Rustenbeck, Ingo

Traffic, May 2015, Vol.16(5), pp.493-509 [Peer Reviewed Journal]

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12
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Article
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Lysosomes in nutrient signalling: A focus on pancreatic β‐cells

Mészáros, Gergő ; Pasquier, Adrien ; Vivot, Kevin ; Goginashvili, Alexander ; Ricci, Romeo

Diabetes, Obesity and Metabolism, September 2018, Vol.20, pp.104-115 [Peer Reviewed Journal]

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Article
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Ultrastructural and immunohistochemical analysis of the 8-20 week human fetal pancreas

Riopel, Matthew ; Li, Jinming ; Fellows, George F ; Goodyer, Cynthia G ; Wang, Rennian

Islets, 04 July 2014, Vol.6(4) [Peer Reviewed Journal]

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14
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Article
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Disrupted dynamics of F-actin and insulin granule fusion in INS-1 832/13 beta-cells exposed to glucotoxicity: partial restoration by glucagon-like peptide 1

Quinault, Aurore ; Gausseres, Blandine ; Bailbe, Danielle ; Chebbah, Nella ; Portha, Bernard ; Movassat, Jamileh ; Tourrel-Cuzin, Cecile

BBA - Molecular Basis of Disease, August 2016, Vol.1862(8), pp.1401-1411 [Peer Reviewed Journal]

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15
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Article
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Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration

Okamoto, M. ; Ohara-Imaizumi, M. ; Kubota, N. ; Hashimoto, S. ; Eto, K. ; Kanno, T. ; Kubota, T. ; Wakui, M. ; Nagai, R. ; Noda, M. ; Nagamatsu, S. ; Kadowaki, T.

Diabetologia, 2008, Vol.51(5), pp.827-835 [Peer Reviewed Journal]

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16
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Article
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Monitoring of glucose-regulated single insulin secretory granule movement by selective photoactivation

Baltrusch, S. ; Lenzen, S.

Diabetologia, 2008, Vol.51(6), pp.989-996 [Peer Reviewed Journal]

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17
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Article
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Contributions of Intracellular Compartments to Calcium Dynamics: Implicating an Acidic Store

Duman, Joseph G. ; Chen, Liangyi ; Palmer, Amy E. ; Hille, Bertil

Traffic, July 2006, Vol.7(7), pp.859-872 [Peer Reviewed Journal]

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18
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Apolipoprotein A-I primes beta cells to increase glucose stimulated insulin secretion

Nilsson, Oktawia ; Del Giudice, Rita ; Nagao, Mototsugu ; Grönberg, Caitriona ; Eliasson, Lena ; Lagerstedt, Jens O

BBA - Molecular Basis of Disease [Peer Reviewed Journal]

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19
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Conference Proceeding
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A new biphasic minimal model

Morris, H.C ; O'Reilly, B ; Streja, D

The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2004, Vol.1, pp.782-785

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