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A Potent, Nonpeptidyl 1 H -Quinolone Antagonist for the Gonadotropin-Releasing Hormone Receptor
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A Potent, Nonpeptidyl 1 H -Quinolone Antagonist for the Gonadotropin-Releasing Hormone Receptor

Devita, Robert J. ; Walsh, Thomas F. ; Young, Jonathan R. ; Jiang, Jinlong ; Ujjainwalla, Feroze ; Toupence, Richard B. ; Parikh, Mamta ; Huang, Song X. ; Fair, Jason A. ; Goulet, Mark T. ; Wyvratt, Matthew J. ; Lo, Jane-L. ; Ren, Ning ; Yudkovitz, Joel B. ; Yang, Yi T. ; Cheng, Kang ; Cui, Jisong ; Mount, George ; Rohrer, Susan P. ; Schaeffer, James M. ; Rhodes, Linda ; Drisko, Jennifer E. ; Mcgowan, Erin ; Macintyre, D. Euan ; Vincent, Styliani ; Carlin, Josephine R. ; Cameron, Judith ; Smith, Roy G.

Journal of Medicinal Chemistry, 03/2001, Vol.44(6), pp.917-922 [Peer Reviewed Journal]

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Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides

Walsh, Thomas F ; Toupence, Richard B ; Young, Jonathan R ; Huang, Song X ; Ujjainwalla, Feroze ; Devita, Robert J ; Goulet, Mark T ; Wyvratt, Matthew J ; Fisher, Michael H ; Lo, Jane-Ling ; Ren, Ning ; Yudkovitz, Joel B ; Yang, Yi Tien ; Cheng, Kang ; Smith, Roy G

Bioorganic & Medicinal Chemistry Letters, 2000, Vol.10(5), pp.443-447 [Peer Reviewed Journal]

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Quinolones as gonadotropin releasing hormone (GnRH) antagonists: simultaneous optimization of the C(3)-aryl and C(6)-substituents

Young, Jonathan R ; Huang, Song X ; Chen, Irene ; Walsh, Thomas F ; Devita, Robert J ; Wyvratt, Matthew J ; Goulet, Mark T ; Ren, Ning ; Lo, Jane ; Yang, Yi Tien ; Yudkovitz, Joel B ; Cheng, Kang ; Smith, Roy G

Bioorganic & Medicinal Chemistry Letters, 2000, Vol.10(15), pp.1723-1727 [Peer Reviewed Journal]

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Lead optimization of 5,6-diarylpyridines as CB1 receptor inverse agonists

Madsen-Duggan, Christina B ; Debenham, John S ; Walsh, Thomas F ; Toupence, Richard B ; Huang, Song X ; Wang, Junying ; Tong, Xinchun ; Lao, Julie ; Fong, Tung M ; Schaeffer, Marie-Therese ; Xiao, Jing Chen ; Huang, Cathy R.-R.C ; Shen, Chun-Pyn ; Stribling, D. Sloan ; Shearman, Lauren P ; Strack, Alison M ; Macintyre, D. Euan ; Van Der Ploeg, Lex H.T ; Goulet, Mark T

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(7), pp.2031-2035 [Peer Reviewed Journal]

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2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: optimization of the tryptamine side chain

Young, Jonathan R ; Huang, Song X ; Walsh, Thomas F ; Wyvratt, Matthew J ; Yang, Yi Tien ; Yudkovitz, Joel B ; Cui, Jisong ; Mount, George R ; Ren, Rena Ning ; Wu, Tsuei-Ju ; Shen, Xiaolan ; Lyons, Kathryn A ; Mao, An-Hua ; Carlin, Josephine R ; Karanam, Bindhu V ; Vincent, Stella H ; Cheng, Kang ; Goulet, Mark T

Bioorganic & Medicinal Chemistry Letters, 2002, Vol.12(5), pp.827-832 [Peer Reviewed Journal]

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Quinazolinones 1: design and synthesis of potent quinazolinone- containing AT 1-selective angiotensin-II receptor antagonists

Allen, Eric E ; de Laszlo, Stephen E ; Huang, Song X ; Quagliato, Carol S ; Greenlee, William J ; Chang, Raymond S.L ; Chen, Tsing-Bau ; Faust, Kristie A ; Lotti, Victor J

Bioorganic & Medicinal Chemistry Letters, 1993, Vol.3(6), pp.1293-1298 [Peer Reviewed Journal]

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