skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Index

Results 1 - 50 of 65  for Everything (Includes Articles)

Results 1 2 next page
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Material Type:
Article
Add to e-Shelf

Correlates of change in health care worker seasonal influenza vaccination rates among dialysis facilities

Lynch, Janet R ; Armistead, Nancy ; Vinson, Brandy B ; Howard, Andrew D

AJIC: American Journal of Infection Control, 01 April 2015, Vol.43(4), pp.409-411 [Peer Reviewed Journal]

Full text available

View all versions
2
Material Type:
Article
Add to e-Shelf

Duodenal‐jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice

Shang, Jin ; Castro‐Perez, Jose M. ; Shen, Xiaolan ; Zhu, Yonghua ; Liu, Haiying ; Qian, Ying ; Previs, Stephen ; Howard, Andrew D. ; Erion, Mark ; Kelley, David E. ; Wang, Liangsu

Obesity, September 2016, Vol.24(9), pp.1938-1945 [Peer Reviewed Journal]

Full text available

View all versions
3
Material Type:
Article
Add to e-Shelf

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent

Pachanski, Michele J ; Kirkland, Melissa E ; Kosinski, Daniel T ; Mane, Joel ; Cheewatrakoolpong, Boonlert ; Xue, Jiyan ; Szeto, Daphne ; Forrest, Gail ; Miller, Corin ; Bunzel, Michelle ; Plummer, Christopher W ; Chobanian, Harry R ; Miller, Michael W ; Souza, Sarah ; Thomas-Fowlkes, Brande S ; Ogawa, Aimie M ; Weinglass, Adam B ; Di Salvo, Jerry ; Li, Xiaoyan ; Feng, Yue ; Tatosian, Daniel A ; Howard, Andrew D ; Colletti, Steven L ; Trujillo, Maria E

PloS one, 2017, Vol.12(10), pp.e0186033 [Peer Reviewed Journal]

Full text available

View all versions
4
Material Type:
Article
Add to e-Shelf

Improving Influenza Vaccination in Dialysis Facilities

Lynch, Janet R ; Frankovich, Edith ; Tetrick, Claire A ; Howard, Andrew D

American Journal of Medical Quality, 12 November 2010, Vol.25(6), pp.416-428 [Peer Reviewed Journal]

Full text available

View all versions
5
Material Type:
Article
Add to e-Shelf

Design of potent and selective GPR119 agonists for type II diabetes

Szewczyk, Jason W ; Acton, John ; Adams, Alan D ; Chicchi, Gary ; Freeman, Stanley ; Howard, Andrew D ; Huang, Yong ; Li, Cai ; Meinke, Peter T ; Mosely, Ralph ; Murphy, Elizabeth ; Samuel, Rachel ; Santini, Conrad ; Yang, Meng ; Zhang, Yong ; Zhao, Kake ; Wood, Harold B

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(9), pp.2665-2669 [Peer Reviewed Journal]

Full text available

View all versions
6
Material Type:
Article
Add to e-Shelf

Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists

Lai, Zhong ; He, Shuwen ; Sherer, Edward C ; Wu, Zhicai ; Yu, Yang ; Ball, Richard ; Hong, Qingmei ; Yang, David X ; Guo, Liangqing ; Li, Derun ; Tuang, Quang ; Chicchi, Gary G ; Trusca, Dorina ; Tsao, Kwei-Lan ; Zhou, Yun-Ping ; Howard, Andrew D ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 01 September 2015, Vol.25(17), pp.3520-3525 [Peer Reviewed Journal]

Full text available

View all versions
7
Material Type:
Article
Add to e-Shelf

GPR40 reduces food intake and body weight through GLP-1

Gorski, Judith N ; Pachanski, Michele J ; Mane, Joel ; Plummer, Christopher W ; Souza, Sarah ; Thomas-Fowlkes, Brande S ; Ogawa, Aimie M ; Weinglass, Adam B ; Di Salvo, Jerry ; Cheewatrakoolpong, Boonlert ; Howard, Andrew D ; Colletti, Steven L ; Trujillo, Maria E

American journal of physiology. Endocrinology and metabolism, 01 July 2017, Vol.313(1), pp.E37-E47 [Peer Reviewed Journal]

Full text available

View all versions
8
Material Type:
Article
Add to e-Shelf

3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists

Walsh, Shawn P ; Severino, Alexandra ; Zhou, Changyou ; He, Jiafang ; Liang, Gui-Bai ; Tan, Carina P ; Cao, Jin ; Eiermann, George J ; Xu, Ling ; Salituro, Gino ; Howard, Andrew D ; Mills, Sander G ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(11), pp.3390-3394 [Peer Reviewed Journal]

Full text available

View all versions
9
Material Type:
Article
Add to e-Shelf

GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

Hauge, Maria ; Vestmar, Marie A ; Husted, Anna S ; Ekberg, Jeppe P ; Wright, Michael J ; Di Salvo, Jerry ; Weinglass, Adam B ; Engelstoft, Maja S ; Madsen, Andreas N ; Lückmann, Michael ; Miller, Michael W ; Trujillo, Maria E ; Frimurer, Thomas M ; Holst, Birgitte ; Howard, Andrew D ; Schwartz, Thue W

Molecular Metabolism, January 2015, Vol.4(1), pp.3-14 [Peer Reviewed Journal]

Full text available

View all versions
10
Material Type:
Article
Add to e-Shelf

Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists

Liu, Weiguo ; Hussain, Zahid ; Zang, Yi ; Sweis, Ramzi F ; Romero, F Anthony ; Finke, Paul E ; Moningka, Remond ; Bao, Jianming ; Plotkin, Michael A ; Shang, Jin ; Dingley, Karen H ; Salituro, Gino ; Murphy, Beth Ann ; Howard, Andrew D ; Ujjainwalla, Feroze ; Wood, Harold B ; Duffy, Joseph L

ACS medicinal chemistry letters, 08 November 2018, Vol.9(11), pp.1088-1093 [Peer Reviewed Journal]

Full text available

View all versions
11
Material Type:
Article
Add to e-Shelf

Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells

Shang, Jin ; Li, Jing ; Keller, Mark P ; Hohmeier, Hans E ; Wang, Yong ; Feng, Yue ; Zhou, Heather H ; Shen, Xiaolan ; Rabaglia, Mary ; Soni, Mufaddal ; Attie, Alan D ; Newgard, Christopher B ; Thornberry, Nancy A ; Howard, Andrew D ; Zhou, Yun-Ping

Molecular endocrinology (Baltimore, Md.), September 2015, Vol.29(9), pp.1243-53 [Peer Reviewed Journal]

Full text available

12
Material Type:
Article
Add to e-Shelf

The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets

Li, Xiaoyan Nina ; Herrington, James ; Petrov, Aleksandr ; Ge, Lan ; Eiermann, George ; Xiong, Yusheng ; Jensen, Mette V ; Hohmeier, Hans E ; Newgard, Christopher B ; Garcia, Maria L ; Wagner, Michael ; Zhang, Bei B ; Thornberry, Nancy A ; Howard, Andrew D ; Kaczorowski, Gregory J ; Zhou, Yun-Ping

The Journal of pharmacology and experimental therapeutics, February 2013, Vol.344(2), pp.407-16 [Peer Reviewed Journal]

Full text available

13
Material Type:
Article
Add to e-Shelf

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

Mu, James ; Petrov, Aleksandr ; Eiermann, George J ; Woods, John ; Zhou, Yun-Ping ; Li, Zhihua ; Zycband, Emanuel ; Feng, Yue ; Zhu, Lan ; Roy, Ranabir Sinha ; Howard, Andrew D ; Li, Cai ; Thornberry, Nancy A ; Zhang, Bei B

European Journal of Pharmacology, 2009, Vol.623(1), pp.148-154 [Peer Reviewed Journal]

Full text available

View all versions
14
Material Type:
Article
Add to e-Shelf

Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1

Bednarek, Maria A ; Tan, Carina ; Hreniuk, Donna L ; Palyha, Oksana C ; Macneil, Douglas J ; Van Der Ploeg, Lex H Y ; Howard, Andrew D ; Feighner, Scott D

The Journal of biological chemistry, 19 April 2002, Vol.277(16), pp.13821-6 [Peer Reviewed Journal]

Full text available

15
Material Type:
Article
Add to e-Shelf

A role for the melanocortin 4 receptor in sexual function

Van Der Ploeg, Lex H T ; Martin, William J ; Howard, Andrew D ; Nargund, Ravi P ; Austin, Christopher P ; Guan, Xiaoming ; Drisko, Jennifer ; Cashen, Doreen ; Sebhat, Iyassu ; Patchett, Arthur A ; Figueroa, David J ; Dilella, Anthony G ; Connolly, Brett M ; Weinberg, David H ; Tan, Carina P ; Palyha, Oksana C ; Pong, Sheng-Shung ; Macneil, Tanya ; Rosenblum, Charles ; Vongs, Aurawan ; Tang, Rui ; Yu, Hong ; Sailer, Andreas W ; Fong, Tung Ming ; Huang, Cathy ; Tota, Michael R ; Chang, Ray S ; Stearns, Ralph ; Tamvakopoulos, Constantin ; Christ, George ; Drazen, Deborah L ; Spar, Brian D ; Nelson, Randy J ; Macintyre, D Euan

Proceedings of the National Academy of Sciences of the United States of America, 20 August 2002, Vol.99(17), pp.11381-6 [Peer Reviewed Journal]

Full text available

View all versions
16
Material Type:
Article
Add to e-Shelf

Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1

Bednarek, Maria A ; Hreniuk, Donna L ; Tan, Carina ; Palyha, Oksana C ; Macneil, Douglas J ; Van Der Ploeg, Lex H Y ; Howard, Andrew D ; Feighner, Scott D

Biochemistry, 21 May 2002, Vol.41(20), pp.6383-90 [Peer Reviewed Journal]

Full text available

View all versions
17
Short Segment of Human Melanin-Concentrating Hormone That Is Sufficient for Full Activation of Human Melanin-Concentrating Hormone Receptors 1 and 2
Material Type:
Article
Add to e-Shelf

Short Segment of Human Melanin-Concentrating Hormone That Is Sufficient for Full Activation of Human Melanin-Concentrating Hormone Receptors 1 and 2

Bednarek, Maria A. ; Feighner, Scott D. ; Hreniuk, Donna L. ; Palyha, Oksana C. ; Morin, Nancy R. ; Sadowski, Sharon J. ; Macneil, Douglas J. ; Howard, Andrew D. ; Van Der Ploeg, Lex H. Y.

Biochemistry, 08/2001, Vol.40(31), pp.9379-9386 [Peer Reviewed Journal]

Full text available

View all versions
18
Material Type:
Article
Add to e-Shelf

The IL‐1β Converting Enzyme as a Therapeutic Target

Miller, Douglas K. ; Calaycay, Jimmy R. ; Chapman, Kevin T. ; Howard, Andrew D. ; Kostura, Matthew J. ; Molineaux, Susan M. ; Thornberry, Nancy A.

Annals of the New York Academy of Sciences, November 1993, Vol.696(1), pp.133-148 [Peer Reviewed Journal]

Full text available

View all versions
19
Material Type:
Article
Add to e-Shelf

Corrigendum to “Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects” [Bioorg. Med. Chem. Lett. 26 (2016) 5724–5728]

Lombardo, Matthew ; Bender, Kate ; London, Clare ; Plotkin, Michael A ; Kirkland, Melissa ; Mane, Joel ; Pachanski, Michele ; Geissler, Wayne ; Cummings, John ; Habulihaz, Bahanu ; Akiyama, Taro E ; Di Salvo, Jerry ; Madeira, Maria ; Pols, Joanna ; Powles, Mary Ann ; Finley, Michael F ; Johnson, Eric ; Roussel, Thomas ; Uebele, Victor N ; Crespo, Alejandro ; Leung, Dennis ; Alleyne, Candice ; Trusca, Dorina ; Lei, Ying ; Howard, Andrew D ; Ujjainwalla, Feroze ; Tata, James R ; Sinz, Christopher J

Bioorganic & Medicinal Chemistry Letters, 01 March 2017, Vol.27(5), pp.1333-1333 [Peer Reviewed Journal]

Full text available

View all versions
20
Material Type:
Article
Add to e-Shelf

Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition

Liu, Weiguo ; Shao, Pengcheng P ; Liang, Gui-Bai ; Bawiec, John ; He, Jiafang ; Aster, Susan D ; Wu, Margaret ; Chicchi, Garry ; Wang, John ; Tsao, Kwei-Lan ; Shang, Jin ; Salituro, Gino ; Zhou, Yun-Ping ; Li, Cai ; Akiyama, Taro E ; Metzger, Daniel E ; Murphy, Beth Ann ; Howard, Andrew D ; Weber, Ann E ; Duffy, Joseph L

ACS medicinal chemistry letters, 08 November 2018, Vol.9(11), pp.1082-1087 [Peer Reviewed Journal]

Full text available

View all versions
21
Material Type:
Article
Add to e-Shelf

Design and Synthesis of Novel, Selective GPR40 AgoPAMs

Plummer, Christopher W ; Clements, Matthew J ; Chen, Helen ; Rajagopalan, Murali ; Josien, Hubert ; Hagmann, William K ; Miller, Michael ; Trujillo, Maria E ; Kirkland, Melissa ; Kosinski, Daniel ; Mane, Joel ; Pachanski, Michele ; Cheewatrakoolpong, Boonlert ; Nolting, Andrew F ; Orr, Robert ; Christensen, Melodie ; Campeau, Louis-Charles ; Wright, Michael J ; Bugianesi, Randal ; Souza, Sarah ; Zhang, Xiaoping ; Di Salvo, Jerry ; Weinglass, Adam B ; Tschirret-Guth, Richard ; Nargund, Ravi ; Howard, Andrew D ; Colletti, Steven L

ACS medicinal chemistry letters, 09 February 2017, Vol.8(2), pp.221-226 [Peer Reviewed Journal]

Full text available

View all versions
22
Material Type:
Article
Add to e-Shelf

Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs

Chen, Helen Y ; Plummer, Christopher W ; Xiao, Dong ; Chobanian, Harry R ; Demong, Duane ; Miller, Michael ; Trujillo, Maria E ; Kirkland, Melissa ; Kosinski, Daniel ; Mane, Joel ; Pachanski, Michele ; Cheewatrakoolpong, Boonlert ; Di Salvo, Jerry ; Thomas-Fowlkes, Brande ; Souza, Sarah ; Tatosian, Daniel A ; Chen, Qing ; Hafey, Michael J ; Houle, Robert ; Nolting, Andrew F ; Orr, Robert ; Ehrhart, Juliann ; Weinglass, Adam B ; Tschirret-Guth, Richard ; Howard, Andrew D ; Colletti, Steven L

ACS medicinal chemistry letters, 12 July 2018, Vol.9(7), pp.685-690 [Peer Reviewed Journal]

Full text available

View all versions
23
Material Type:
Article
Add to e-Shelf

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy

Satapati, Santhosh ; Qian, Ying ; Wu, Margaret S ; Petrov, Aleksandr ; Dai, Ge ; Wang, Sheng-Ping ; Zhu, Yonghua ; Shen, Xiaolan ; Muise, Eric S ; Chen, Ying ; Zycband, Emanuel ; Weinglass, Adam ; Di Salvo, Jerry ; Debenham, John S ; Cox, Jason M ; Lan, Ping ; Shah, Vinit ; Previs, Stephen F ; Erion, Mark ; Kelley, David E ; Wang, Liangsu ; Howard, Andrew D ; Shang, Jin

Journal of lipid research, August 2017, Vol.58(8), pp.1561-1578 [Peer Reviewed Journal]

Full text available

24
Material Type:
Article
Add to e-Shelf

Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects

Lombardo, Matthew ; Bender, Kate ; London, Clare ; Plotkin, Michael A ; Kirkland, Melissa ; Mane, Joel ; Pachanski, Michele ; Geissler, Wayne ; Cummings, John ; Habulihaz, Bahanu ; Akiyama, Taro E ; Di Salvo, Jerry ; Madeira, Maria ; Pols, Joanna ; Powles, Mary Ann ; Finley, Michael F ; Johnson, Eric ; Roussel, Thomas ; Uebele, Victor N ; Crespo, Alejandro ; Leung, Dennis ; Alleyne, Candice ; Trusca, Dorina ; Lei, Ying ; Howard, Andrew D ; Ujjainwalla, Feroze ; Tata, James R ; Sinz, Christopher J

Bioorganic & Medicinal Chemistry Letters, 01 December 2016, Vol.26(23), pp.5724-5728 [Peer Reviewed Journal]

Full text available

View all versions
25
Material Type:
Article
Add to e-Shelf

Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist

Pasternak, Alexander ; Feng, Zhe ; De Jesus, Reynalda ; Ye, Zhixiong ; He, Shuwen ; Dobbelaar, Peter ; Bradley, Scott A ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Eiermann, George J ; Li, Cai ; Feng, Yue ; Wu, Margaret ; Shao, Qing ; Zhang, Bei B ; Nargund, Ravi ; Mills, Sander G ; Howard, Andrew D ; Yang, Lihu ; Zhou, Yun-Ping

ACS medicinal chemistry letters, 12 April 2012, Vol.3(4), pp.289-93 [Peer Reviewed Journal]

Full text available

View all versions
26
Material Type:
Article
Add to e-Shelf

Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists

Li, Derun ; Wu, Zhicai ; Yu, Yang ; Ball, Richard G ; Guo, Liangqin ; Sherer, Edward ; He, Shuwen ; Hong, Qingmei ; Lai, Zhong ; Qi, Hongbo ; Truong, Quang ; Yang, David X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Trujillo, Maria ; Pachanski, Michele ; Eiermann, George J ; Howard, Andrew D ; Zhou, Yun-Ping ; Zhang, Bei B ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 12 June 2014, Vol.5(6), pp.690-5 [Peer Reviewed Journal]

Full text available

View all versions
27
Material Type:
Article
Add to e-Shelf

Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists

Zhou, Changyou ; Tang, Cheng ; Chang, Eric ; Ge, Min ; Lin, Songnian ; Cline, Eric ; Tan, Carina P ; Feng, Yue ; Zhou, Yun-Ping ; Eiermann, George J ; Petrov, Aleksandr ; Salituro, Gino ; Meinke, Peter ; Mosley, Ralph ; Akiyama, Taro E ; Einstein, Monica ; Kumar, Sanjeev ; Berger, Joel ; Howard, Andrew D ; Thornberry, Nancy ; Mills, Sander G ; Yang, Lihu

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(3), pp.1298-1301 [Peer Reviewed Journal]

Full text available

View all versions
28
Material Type:
Article
Add to e-Shelf

Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice

Tan, Carina P ; Feng, Yue ; Zhou, Yun-Ping ; Eiermann, George J ; Petrov, Aleksandr ; Zhou, Changyou ; Lin, Songnian ; Salituro, Gino ; Meinke, Peter ; Mosley, Ralph ; Akiyama, Taro E ; Einstein, Monica ; Kumar, Sanjeev ; Berger, Joel P ; Mills, Sander G ; Thornberry, Nancy A ; Yang, Lihu ; Howard, Andrew D

Diabetes, August 2008, Vol.57(8), pp.2211-9 [Peer Reviewed Journal]

Full text available

View all versions
29
Material Type:
Article
Add to e-Shelf

Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes

Mu, James ; Woods, John ; Zhou, Yun-Ping ; Roy, Ranabir Sinha ; Li, Zhihua ; Zycband, Emanuel ; Feng, Yue ; Zhu, Lan ; Li, Cai ; Howard, Andrew D ; Moller, David E ; Thornberry, Nancy A ; Zhang, Bei B

Diabetes, June 2006, Vol.55(6), pp.1695-704 [Peer Reviewed Journal]

Full text available

View all versions
30
Material Type:
Article
Add to e-Shelf

Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Lai, Zhong ; Ye, Zhixiong ; Dobbelaar, Peter H ; Shah, Shrenik K ; Truong, Quang ; Du, Wu ; Guo, Liangqin ; Liu, Jian ; Jian, Tianying ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James ; Reibarkh, Mikhail ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

ACS medicinal chemistry letters, 10 July 2014, Vol.5(7), pp.748-53 [Peer Reviewed Journal]

Full text available

View all versions
31
Material Type:
Article
Add to e-Shelf

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Guo, Liangqin ; Parker, Dann L ; Zang, Yi ; Sweis, Ramzi F ; Liu, Weiguo ; Sherer, Edward C ; Buist, Nicole ; Terebetski, Jenna ; Kelly, Terri ; Bugianesi, Randal ; Priest, Birgit T ; Dingley, Karen H ; Li, Xiaofang ; Mitelman, Stan ; Salituro, Gino ; Trujillo, Maria E ; Pachanski, Michele ; Kirkland, Melissa ; Powles, Mary Ann ; Eiermann, George J ; Feng, Yue ; Shang, Jin ; Howard, Andrew D ; Ujjainwalla, Feroze ; Sinz, Christopher J ; Debenham, John S ; Edmondson, Scott D ; Nargund, Ravi P ; Hagmann, William K ; Li, Derun

ACS medicinal chemistry letters, 08 December 2016, Vol.7(12), pp.1107-1111 [Peer Reviewed Journal]

Full text available

View all versions
32
Material Type:
Article
Add to e-Shelf

SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists

He, Shuwen ; Dobbelaar, Peter H ; Guo, Liangqin ; Ye, Zhixiong ; Liu, Jian ; Jian, Tianying ; Truong, Quang ; Shah, Shrenik K ; Du, Wu ; Qi, Hongbo ; Bakshi, Raman K ; Hong, Qingmei ; Dellureficio, James D ; Sherer, Edward ; Pasternak, Alexander ; Feng, Zhe ; Reibarkh, Mikhail ; Lin, Melissa ; Samuel, Koppara ; Reddy, Vijay B ; Mitelman, Stan ; Tong, Sharon X ; Chicchi, Gary G ; Tsao, Kwei-Lan ; Trusca, Dorina ; Wu, Margaret ; Shao, Qing ; Trujillo, Maria E ; Fernandez, Guillermo ; Nelson, Donald ; Bunting, Patricia ; Kerr, Janet ; Fitzgerald, Patrick ; Morissette, Pierre ; Volksdorf, Sylvia ; Eiermann, George J ; Li, Cai ; Zhang, Bei B ; Howard, Andrew D ; Zhou, Yun-Ping ; Nargund, Ravi P ; Hagmann, William K

Bioorganic & Medicinal Chemistry Letters, 15 March 2016, Vol.26(6), pp.1529-1535 [Peer Reviewed Journal]

Full text available

View all versions
33
Material Type:
Article
Add to e-Shelf

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Lu, Jun ; Byrne, Noel ; Wang, John ; Bricogne, Gerard ; Brown, Frank K ; Chobanian, Harry R ; Colletti, Steven L ; Di Salvo, Jerry ; Thomas-Fowlkes, Brande ; Guo, Yan ; Hall, Dawn L ; Hadix, Jennifer ; Hastings, Nicholas B ; Hermes, Jeffrey D ; Ho, Thu ; Howard, Andrew D ; Josien, Hubert ; Kornienko, Maria ; Lumb, Kevin J ; Miller, Michael W ; Patel, Sangita B ; Pio, Barbara ; Plummer, Christopher W ; Sherborne, Bradley S ; Sheth, Payal ; Souza, Sarah ; Tummala, Srivanya ; Vonrhein, Clemens ; Webb, Maria ; Allen, Samantha J ; Johnston, Jennifer M ; Weinglass, Adam B ; Sharma, Sujata ; Soisson, Stephen M Argonne National Lab. (Anl), Argonne, Il (United States). Advanced Photon Source (APS) (Corporate Author)

Nature Structural & Molecular Biology, 05 June 2017, Vol.24(7) [Peer Reviewed Journal]

Full text available

View all versions
34
Material Type:
Article
Add to e-Shelf

Activation of melanocortin MC 4 receptors increases erectile activity in rats ex copula

Martin, William J ; Mcgowan, Erin ; Cashen, Doreen E ; Gantert, Liza T ; Drisko, Jennifer E ; Hom, Gary J ; Nargund, Ravi ; Sebhat, Iyassu ; Howard, Andrew D ; Van Der Ploeg, Lex H.T ; Macintyre, D.Euan

European Journal of Pharmacology, 2002, Vol.454(1), pp.71-79 [Peer Reviewed Journal]

Full text available

View all versions
35
Material Type:
Article
Add to e-Shelf

Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats

Shearman, Lauren P ; Camacho, Ramon E ; Sloan Stribling, D ; Zhou, Dan ; Bednarek, Maria A ; Hreniuk, Donna L ; Feighner, Scott D ; Tan, Carina P ; Howard, Andrew D ; Van Der Ploeg, Lex H.T ; Macintyre, D.Euan ; Hickey, Gerard J ; Strack, Alison M

European Journal of Pharmacology, 2003, Vol.475(1), pp.37-47 [Peer Reviewed Journal]

Full text available

View all versions
36
Material Type:
Article
Add to e-Shelf

Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity

Liu, Jian ; He, Shuwen ; Jian, Tianying ; Dobbelaar, Peter H ; Sebhat, Iyassu K ; Lin, Linus S ; Goodman, Allan ; Guo, Cheng ; Guzzo, Peter R ; Hadden, Mark ; Henderson, Alan J ; Pattamana, Kevin ; Ruenz, Megan ; Sargent, Bruce J ; Swenson, Brian ; Yet, Larry ; Tamvakopoulos, Constantin ; Peng, Qianping ; Pan, Jie ; Kan, Yanqing ; Palyha, Oksana ; Kelly, Theresa M ; Guan, Xiao-Ming ; Howard, Andrew D ; Marsh, Donald J ; Metzger, Joseph M ; Reitman, Marc L ; Wyvratt, Matthew J ; Nargund, Ravi P

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(7), pp.2074-2077 [Peer Reviewed Journal]

Full text available

View all versions