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1
In vitro studies evaluating the activity of imipenem in combination with relebactam against Pseudomonas aeruginosa
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In vitro studies evaluating the activity of imipenem in combination with relebactam against Pseudomonas aeruginosa

Young, Katherine ; Painter, Ronald E ; Raghoobar, Susan L ; Hairston, Nichelle N ; Racine, Fred ; Wisniewski, Douglas ; Balibar, Carl J ; Villafania, Artjohn ; Zhang, Rumin ; Sahm, Daniel F ; Blizzard, Timothy ; Murgolo, Nicholas ; Hammond, Milton L ; Motyl, Mary R

BMC microbiology, 2019, Vol.19 (1), p.150-14 [Peer Reviewed Journal]

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2
Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin
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Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin

Blizzard, Timothy A ; Chen, Helen ; Kim, Seongkon ; Wu, Jane ; Bodner, Rena ; Gude, Candido ; Imbriglio, Jason ; Young, Katherine ; Park, Young-Whan ; Ogawa, Aimie ; Raghoobar, Susan ; Hairston, Nichelle ; Painter, Ronald E ; Wisniewski, Doug ; Scapin, Giovanna ; Fitzgerald, Paula ; Sharma, Nandini ; Lu, Jun ; Ha, Sookhee ; Hermes, Jeff ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2014, Vol.24 (3), p.780-785 [Peer Reviewed Journal]

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3
Synthesis and biological evaluation of platensimycin analogs
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Synthesis and biological evaluation of platensimycin analogs

Shen, Hong C ; Ding, Fa-Xiang ; Singh, Sheo B ; Parthasarathy, Gopalakrishnan ; Soisson, Stephen M ; Ha, Sookhee N ; Chen, Xun ; Kodali, Srinivas ; Wang, Jun ; Dorso, Karen ; Tata, James R ; Hammond, Milton L ; Maccoss, Malcolm ; Colletti, Steven L

Bioorganic & medicinal chemistry letters, 2009-03-15, Vol.19 (6), p.1623-1627 [Peer Reviewed Journal]

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4
Succinic Acids as Potent Inhibitors of Plasmid-borne IMP-1 Metallo-β-lactamase
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Succinic Acids as Potent Inhibitors of Plasmid-borne IMP-1 Metallo-β-lactamase

Toney, Jeffrey H ; Hammond, Gail G ; Fitzgerald, Paula M. D ; Sharma, Nandini ; Balkovec, James M ; Rouen, Gregory P ; Olson, Steven H ; Hammond, Milton L ; Greenlee, Mark L ; Gao, Ying-Duo

The Journal of biological chemistry, 2001, Vol.276 (34), p.31913-31918 [Peer Reviewed Journal]

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5
Side chain SAR of bicyclic [beta]-lactamase inhibitors . 1. Discovery of a class C BLI for combination with imipinem
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Side chain SAR of bicyclic [beta]-lactamase inhibitors . 1. Discovery of a class C BLI for combination with imipinem

Blizzard, Timothy A ; Chen, Helen ; Kim, Seongkon ; Wu, Jane ; Young, Katherine ; Park, Young-Whan ; Ogawa, Amy ; Raghoobar, Susan ; Painter, Ronald E ; Hairston, Nichelle ; Lee, Sang Ho ; Misura, Andrew ; Felcetto, Tom ; Fitzgerald, Paula ; Sharma, Nandini ; Lu, Jun ; Ha, Sookhee ; Hickey, Emily ; Hermes, Jeff ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2010-02-01, Vol.20 (3), p.918 [Peer Reviewed Journal]

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6
Reduced Immunotoxicity and Preservation of Antibacterial Activity in a Releasable Side-Chain Carbapenem Antibiotic
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Reduced Immunotoxicity and Preservation of Antibacterial Activity in a Releasable Side-Chain Carbapenem Antibiotic

Hugh Rosen ; Richard Hajdu ; Lynn Silver ; Helmut Kropp ; Karen Dorso ; Joyce Kohler ; Jon G. Sundelof ; Joann Huber ; Gail G. Hammond ; Jesse J. Jackson ; Charles J. Gill ; Randall Thompson ; Barbara A. Pelak ; Jeffrey H. Epstein-Toney ; George Lankas ; Robert R. Wilkening ; Kenneth J. Wildonger ; Timothy A. Blizzard ; Frank P. DiNinno ; Ronald W. Ratcliffe ; James V. Heck ; John W. Kozarich ; Milton L. Hammond

Science (American Association for the Advancement of Science), 1999-01-29, Vol.283 (5402), p.703-706 [Peer Reviewed Journal]

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7
Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer Protein
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Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer Protein

Thompson, Christopher F ; Ali, Amjad ; Quraishi, Nazia ; Lu, Zhijian ; Hammond, Milton L ; Sinclair, Peter J ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D

ACS medicinal chemistry letters, 2011-06-09, Vol.2 (6), p.424-427 [Peer Reviewed Journal]

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8
Ertapenem: a Group 1 carbapenem with distinct antibacterial and pharmacological properties
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Ertapenem: a Group 1 carbapenem with distinct antibacterial and pharmacological properties

Hammond, Milton L

Journal of antimicrobial chemotherapy, 2004-06, Vol.53 Suppl 2 (suppl_2), p.ii7-ii9 [Peer Reviewed Journal]

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9
6H-Benzo[c]chromen-6-one derivatives as selective ERβ agonists
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6H-Benzo[c]chromen-6-one derivatives as selective ERβ agonists

Sun, Wanying ; Cama, Lovji D ; Birzin, Elizabeth T ; Warrier, Sudha ; Locco, Louis ; Mosley, Ralph ; Hammond, Milton L ; Rohrer, Susan P

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (6), p.1468-1472 [Peer Reviewed Journal]

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10
Biphenyl-Substituted Oxazolidinones as Cholesteryl Ester Transfer Protein Inhibitors: Modifications of the Oxazolidinone Ring Leading to the Discovery of Anacetrapib
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Biphenyl-Substituted Oxazolidinones as Cholesteryl Ester Transfer Protein Inhibitors: Modifications of the Oxazolidinone Ring Leading to the Discovery of Anacetrapib

Smith, Cameron J ; Ali, Amjad ; Hammond, Milton L ; Li, Hong ; Lu, Zhijian ; Napolitano, Joann ; Taylor, Gayle E ; Thompson, Christopher F ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B ; Rosa, Ray ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Sinclair, Peter J

Journal of medicinal chemistry, 2011-07-14, Vol.54 (13), p.4880-4895 [Peer Reviewed Journal]

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11
Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats
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Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats

Shen, Hong C ; Ding, Fa-Xiang ; Deng, Qiaolin ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Carballo-Jane, Ester ; Ren, Ning ; Cai, Tian-Quan ; Wu, Tsuei-Ju ; Wu, Kenneth K ; Cheng, Kang ; Chen, Qing ; Wolff, Michael S ; Tong, Xinchun ; Holt, Tom G ; Waters, M. Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Journal of medicinal chemistry, 2009-04-23, Vol.52 (8), p.2587-2602 [Peer Reviewed Journal]

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12
2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety
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2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (1), p.346-349 [Peer Reviewed Journal]

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13
Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate
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Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate

Shen, Hong C ; Ding, Fa-Xiang ; Raghavan, Subharekha ; Deng, Qiaolin ; Luell, Silvi ; Forrest, Michael J ; Carballo-Jane, Ester ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Wu, Kenneth K ; Wu, Tsuei-Ju ; Cheng, Kang ; Ren, Ning ; Cai, Tian-Quan ; Chen, Qing ; Wang, Junying ; Wolff, Michael S ; Tong, Xinchun ; Holt, Tom G ; Waters, M. Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Journal of medicinal chemistry, 2010-03-25, Vol.53 (6), p.2666-2670 [Peer Reviewed Journal]

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14
2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice
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2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice

Kallashi, Florida ; Kim, Dooseop ; Kowalchick, Jennifer ; Park, You Jung ; Hunt, Julianne A ; Ali, Amjad ; Smith, Cameron J ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B ; Rosa, Raymond ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (1), p.558-561 [Peer Reviewed Journal]

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15
Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene:  Irreversible Enzyme Inhibition and Thiol Adduct Formation
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Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene:  Irreversible Enzyme Inhibition and Thiol Adduct Formation

Chen, Qing ; Ngui, Jason S ; Doss, George A ; Wang, Regina W ; Cai, Xiaoxin ; DiNinno, Frank P ; Blizzard, Timothy A ; Hammond, Milton L ; Stearns, Ralph A ; Evans, David C ; Baillie, Thomas A ; Tang, Wei

Chemical research in toxicology, 2002-07-15, Vol.15 (7), p.907-914 [Peer Reviewed Journal]

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16
Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712
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Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712

Chen, Helen ; Blizzard, Timothy A ; Kim, Seongkon ; Wu, Jane ; Young, Katherine ; Park, Young-Whan ; Ogawa, Aimie M ; Raghoobar, Susan ; Painter, Ronald E ; Wisniewski, Doug ; Hairston, Nichelle ; Fitzgerald, Paula ; Sharma, Nandini ; Scapin, Giovanna ; Lu, Jun ; Hermes, Jeff ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (14), p.4267-4270 [Peer Reviewed Journal]

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17
Estrogen Receptor Ligands. II. Discovery of Benzoxathiins as Potent, Selective Estrogen Receptor α Modulators
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Estrogen Receptor Ligands. II. Discovery of Benzoxathiins as Potent, Selective Estrogen Receptor α Modulators

Kim, Seongkon ; Wu, Jane Y ; Birzin, Elizabeth T ; Frisch, Katalin ; Chan, Wanda ; Pai, Lee-Yuh ; Yang, Yi Tien ; Mosley, Ralph T ; Fitzgerald, Paula M. D ; Sharma, Nandini ; Dahllund, Johanna ; Thorsell, Ann-Gerd ; DiNinno, Frank ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Journal of medicinal chemistry, 2004-04-22, Vol.47 (9), p.2171-2175 [Peer Reviewed Journal]

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18
Succinic Acids as Potent Inhibitors of Plasmid-borne IMP-1 Metallo-β-lactamase
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Succinic Acids as Potent Inhibitors of Plasmid-borne IMP-1 Metallo-β-lactamase

Jeffrey H. Toney ; Gail G. Hammond ; Paula M. D. Fitzgerald ; Nandini Sharma ; James M. Balkovec ; Gregory P. Rouen ; Steven H. Olson ; Milton L. Hammond ; Mark L. Greenlee ; Ying-Duo Gao

Journal of Biological Chemistry, 2001-08-24, Vol.276 (34), p.31913 [Peer Reviewed Journal]

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19
Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii
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Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii

Tan, Qiang ; Ogawa, Aimie M ; Raghoobar, Susan L ; Wisniewski, Douglas ; Colwell, Lawrence ; Park, Young-Whan ; Young, Katherine ; Hermes, Jeffrey D ; DiNinno, Frank P ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (14), p.4363-4365 [Peer Reviewed Journal]

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20
Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinem
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Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinem

Blizzard, Timothy A ; Chen, Helen ; Kim, Seongkon ; Wu, Jane ; Young, Katherine ; Park, Young-Whan ; Ogawa, Amy ; Raghoobar, Susan ; Painter, Ronald E ; Hairston, Nichelle ; Lee, Sang Ho ; Misura, Andrew ; Felcetto, Tom ; Fitzgerald, Paula ; Sharma, Nandini ; Lu, Jun ; Ha, Sookhee ; Hickey, Emily ; Hermes, Jeff ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (3), p.918-921 [Peer Reviewed Journal]

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21
2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy
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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy

Sweis, Ramzi F ; Hunt, Julianne A ; Kallashi, Florida ; Hammond, Milton L ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Rosa, Raymond ; Peterson, Larry ; Sparrow, Carl P ; Wright, Samuel D ; Anderson, Matt S ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (6), p.1890-1895 [Peer Reviewed Journal]

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22
2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety
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2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety

Hunt, Julianne A ; Gonzalez, Silvia ; Kallashi, Florida ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (3), p.1019-1022 [Peer Reviewed Journal]

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23
Discovery of Biaryl Anthranilides as Full Agonists for the High Affinity Niacin Receptor
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Discovery of Biaryl Anthranilides as Full Agonists for the High Affinity Niacin Receptor

Shen, Hong C ; Ding, Fa-Xiang ; Luell, Silvi ; Forrest, Michael J ; Carballo-Jane, Ester ; Wu, Kenneth K ; Wu, Tsuei-Ju ; Cheng, Kang ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Ren, Ning ; Cai, Tian-Quan ; Deng, Qiaolin ; Chen, Qing ; Wang, Junying ; Wolff, Michael S ; Tong, Xinchun ; Holt, Tom G ; Waters, M. Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Journal of medicinal chemistry, 2007-12-13, Vol.50 (25), p.6303-6306 [Peer Reviewed Journal]

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24
Design of a novel class of biphenyl CETP inhibitors
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Design of a novel class of biphenyl CETP inhibitors

Lu, Zhijian ; Napolitano, Joann B ; Theberge, Ashleigh ; Ali, Amjad ; Hammond, Milton L ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (24), p.7469-7472 [Peer Reviewed Journal]

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25
Tetrahydro anthranilic acid as a surrogate for anthranilic acid: Application to the discovery of potent niacin receptor agonists
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Tetrahydro anthranilic acid as a surrogate for anthranilic acid: Application to the discovery of potent niacin receptor agonists

Raghavan, Subharekha ; Tria, G. Scott ; Shen, Hong C ; Ding, Fa-Xiang ; Taggart, Andrew K ; Ren, Ning ; Wilsie, Larrisa C ; Krsmanovic, Mihajlo L ; Holt, Tom G ; Wolff, Michael S ; Waters, M. Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (11), p.3163-3167 [Peer Reviewed Journal]

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26
In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes:  Formation of Reactive Iminium and Quinone Type Metabolites
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In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes:  Formation of Reactive Iminium and Quinone Type Metabolites

Zhang, Zhoupeng ; Chen, Qing ; Li, Ying ; Doss, George A ; Dean, Brian J ; Ngui, Jason S ; Silva Elipe, Maria ; Kim, Seongkon ; Wu, Jane Y ; DiNinno, Frank ; Hammond, Milton L ; Stearns, Ralph A ; Evans, David C ; Baillie, Thomas A ; Tang, Wei

Chemical research in toxicology, 2005-04-18, Vol.18 (4), p.675-685 [Peer Reviewed Journal]

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27
SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors
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SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors

Lu, Zhijian ; Chen, Yi-heng ; Napolitano, Joann B ; Taylor, Gayle ; Ali, Amjad ; Hammond, Milton L ; Deng, Qiaolin ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2012, Vol.22 (1), p.199-203 [Peer Reviewed Journal]

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28
Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERα
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Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERα

Dykstra, Kevin D ; Guo, Liangqin ; Birzin, Elizabeth T ; Chan, Wanda ; Yang, Yi Tien ; Hayes, Edward C ; DaSilva, Carolyn A ; Pai, Lee-Yuh ; Mosley, Ralph T ; Kraker, Bryan ; Fitzgerald, Paula M.D ; DiNinno, Frank ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2007, Vol.17 (8), p.2322-2328 [Peer Reviewed Journal]

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29
Corrigendum to “2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety” [Bioorg. Med. Chem. Lett. 20 (2010) 346]
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Corrigendum to “2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety” [Bioorg. Med. Chem. Lett. 20 (2010) 346]

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (24), p.7555-7555 [Peer Reviewed Journal]

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30
Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A
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Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A

Shen, Hong C ; Taggart, Andrew K.P ; Wilsie, Larissa C ; Waters, M. Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (18), p.4948-4951 [Peer Reviewed Journal]

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31
Novel N-Arylpyrazolo[3,2-c]-Based Ligands for the Glucocorticoid Receptor:  Receptor Binding and in Vivo Activity
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Novel N-Arylpyrazolo[3,2-c]-Based Ligands for the Glucocorticoid Receptor:  Receptor Binding and in Vivo Activity

Ali, Amjad ; Thompson, Christopher F ; Balkovec, James M ; Graham, Donald W ; Hammond, Milton L ; Quraishi, Nazia ; Tata, James R ; Einstein, Monica ; Ge, Lan ; Harris, Georgianna ; Kelly, Terri M ; Mazur, Paul ; Pandit, Shilpa ; Santoro, Joseph ; Sitlani, Ayesha ; Wang, Chuanlin ; Williamson, Joanne ; Miller, Douglas K ; Thompson, Chris M ; Zaller, Dennis M ; Forrest, Michael J ; Carballo-Jane, Ester ; Luell, Silvi

Journal of medicinal chemistry, 2004-05-06, Vol.47 (10), p.2441-2452 [Peer Reviewed Journal]

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32
Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A
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Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A

Ding, Fa-Xiang ; Shen, Hong C ; Wilsie, Larrisa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Ren, Ning ; Cai, Tian-Quan ; Wang, Junying ; Tong, Xinchun ; Holt, Tom G ; Chen, Qing ; Gerard Waters, M ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (11), p.3372-3375 [Peer Reviewed Journal]

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33
Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity
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Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity

Chen, Helen Y ; Dykstra, Kevin D ; Birzin, Elizabeth T ; Frisch, Katalin ; Chan, Wanda ; Yang, Yi T ; Mosley, Ralph T ; DiNinno, Frank ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2004, Vol.14 (6), p.1417-1421 [Peer Reviewed Journal]

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34
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers
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Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers

Blizzard, Timothy A ; DiNinno, Frank ; Morgan, Jerry D ; Chen, Helen Y ; Wu, Jane Y ; Kim, Seongkon ; Chan, Wanda ; Birzin, Elizabeth T ; Yang, Yi Tien ; Pai, Lee-Yuh ; Fitzgerald, Paula M.D ; Sharma, Nandini ; Li, Ying ; Zhang, Zhoupeng ; Hayes, Edward C ; DaSilva, Carolyn A ; Tang, Wei ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 2005, Vol.15 (1), p.107-113 [Peer Reviewed Journal]

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35
Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: Synthesis, in vitro profile, molecular modeling studies, and in vivo experiments
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