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Ertapenem: a Group 1 carbapenem with distinct antibacterial and pharmacological properties

Hammond, Milton L

Journal of Antimicrobial Chemotherapy, 2004, Vol.53(2), pp.ii7-ii9 [Peer Reviewed Journal]

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Ertapenem: a Group 1 carbapenem with distinct antibacterial and pharmacological properties

Hammond, Milton L

The Journal of antimicrobial chemotherapy, June 2004, Vol.53 Suppl 2, pp.ii7-9 [Peer Reviewed Journal]

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Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib

Smith, Cameron J ; Ali, Amjad ; Hammond, Milton L ; Li, Hong ; Lu, Zhijian ; Napolitano, Joann ; Taylor, Gayle E ; Thompson, Christopher F ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B ; Rosa

Journal of medicinal chemistry, 14 July 2011, Vol.54(13), pp.4880-95 [Peer Reviewed Journal]

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Pneumocandin B o acid degradate

Aileen Bouffard, F ; Hammond, Milton L ; Arison, Byron H

Tetrahedron Letters, 1995, Vol.36(9), pp.1405-1408 [Peer Reviewed Journal]

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Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii

Tan, Qiang ; Ogawa, Aimie M ; Raghoobar, Susan L ; Wisniewski, Douglas ; Colwell, Lawrence ; Park, Young-Whan ; Young, Katherine ; Hermes, Jeffrey D ; Dininno, Frank P ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(14), pp.4363-4365 [Peer Reviewed Journal]

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Estrogen receptor ligands. 12. Synthesis of the major metabolites of an ERalpha-selective, dihydrobenzoxathiin antagonist for osteoporosis

Kim, Seongkon ; Wu, Jane Y ; Zhang, Zhoupeng ; Tang, Wei ; Doss, George A ; Dean, Brian J ; Dininno, Frank ; Hammond, Milton L

Organic letters, 03 February 2005, Vol.7(3), pp.411-4 [Peer Reviewed Journal]

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Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712

Chen, Helen ; Blizzard, Timothy A ; Kim, Seongkon ; Wu, Jane ; Young, Katherine ; Park, Young-Whan ; Ogawa, Aimie M ; Raghoobar, Susan ; Painter, Ronald E ; Wisniewski, Doug ; Hairston, Nichelle ; Fitzgerald, Paula ; Sharma, Nandini ; Scapin, Giovanna ; Lu, Jun ; Hermes, Jeff ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(14), pp.4267-4270 [Peer Reviewed Journal]

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Discovery of substituted biphenyl oxazolidinone inhibitors of cholesteryl ester transfer protein

Thompson, Christopher F ; Ali, Amjad ; Quraishi, Nazia ; Lu, Zhijian ; Hammond, Milton L ; Sinclair, Peter J ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D

ACS medicinal chemistry letters, 09 June 2011, Vol.2(6), pp.424-7 [Peer Reviewed Journal]

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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy

Sweis, Ramzi F ; Hunt, Julianne A ; Kallashi, Florida ; Hammond, Milton L ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Rosa, Raymond ; Peterson, Larry ; Sparrow, Carl P ; Wright, Samuel D ; Anderson, Matt S ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2011, Vol.21(6), pp.1890-1895 [Peer Reviewed Journal]

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Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin®

Blizzard, Timothy A ; Chen, Helen ; Kim, Seongkon ; Wu, Jane ; Bodner, Rena ; Gude, Candido ; Imbriglio, Jason ; Young, Katherine ; Park, Young-Whan ; Ogawa, Aimie ; Raghoobar, Susan ; Hairston, Nichelle ; Painter, Ronald E ; Wisniewski, Doug ; Scapin, Giovanna ; Fitzgerald, Paula ; Sharma, Nandini ; Lu, Jun ; Ha, Sookhee ; Hermes

Bioorganic & medicinal chemistry letters, 01 February 2014, Vol.24(3), pp.780-5 [Peer Reviewed Journal]

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SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors

Lu, Zhijian ; Chen, Yi-Heng ; Napolitano, Joann B ; Taylor, Gayle ; Ali, Amjad ; Hammond, Milton L ; Deng, Qiaolin ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D

Bioorganic & Medicinal Chemistry Letters, 01 January 2012, Vol.22(1), pp.199-203 [Peer Reviewed Journal]

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2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice

Kallashi, Florida ; Kim, Dooseop ; Kowalchick, Jennifer ; Park, You Jung ; Hunt, Julianne A ; Ali, Amjad ; Smith, Cameron J ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Cumiskey, Anne-Marie ; Latham, Melanie ; Peterson, Laurence B

Bioorganic & Medicinal Chemistry Letters, 01 January 2011, Vol.21(1), pp.558-561 [Peer Reviewed Journal]

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2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(1), pp.346-349 [Peer Reviewed Journal]

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2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety

Hunt, Julianne A ; Gonzalez, Silvia ; Kallashi, Florida ; Hammond, Milton L ; Pivnichny, James V ; Tong, Xinchun ; Xu, Suoyu S ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(3), pp.1019-1022 [Peer Reviewed Journal]

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Design of a novel class of biphenyl CETP inhibitors

Lu, Zhijian ; Napolitano, Joann B ; Theberge, Ashleigh ; Ali, Amjad ; Hammond, Milton L ; Tan, Eugene ; Tong, Xinchun ; Xu, Suoyu S ; Latham, Melanie J ; Peterson, Laurence B ; Anderson, Matt S ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Chen, Ying ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(24), pp.7469-7472 [Peer Reviewed Journal]

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Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinem

Blizzard, Timothy A ; Chen, Helen ; Kim, Seongkon ; Wu, Jane ; Young, Katherine ; Park, Young-Whan ; Ogawa, Amy ; Raghoobar, Susan ; Painter, Ronald E ; Hairston, Nichelle ; Lee, Sang Ho ; Misura, Andrew ; Felcetto, Tom ; Fitzgerald, Paula ; Sharma, Nandini ; Lu, Jun ; Ha, Sookhee ; Hickey, Emily ; Hermes, Jeff ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(3), pp.918-921 [Peer Reviewed Journal]

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17
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Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats

Shen, Hong C ; Ding, Fa-Xiang ; Deng, Qiaolin ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Carballo-Jane, Ester ; Ren, Ning ; Cai, Tian-Quan ; Wu, Tsuei-Ju ; Wu, Kenneth K ; Cheng, Kang ; Chen, Qing ; Wolff, Michael S ; Tong, Xinchun ; Holt, Tom G ; Waters, M Gerard ; Hammond, Milton L ; Tata, James R ; Colletti

Journal of medicinal chemistry, 23 April 2009, Vol.52(8), pp.2587-602 [Peer Reviewed Journal]

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18
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Corrigendum to “2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety” [Bioorg. Med. Chem. Lett. 20 (2010) 346]

Smith, Cameron J ; Ali, Amjad ; Chen, Liya ; Hammond, Milton L ; Anderson, Matt S ; Chen, Ying ; Eveland, Suzanne S ; Guo, Qiu ; Hyland, Sheryl A ; Milot, Denise P ; Sparrow, Carl P ; Wright, Samuel D ; Sinclair, Peter J

Bioorganic & Medicinal Chemistry Letters, 2010, Vol.20(24), pp.7555-7555 [Peer Reviewed Journal]

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Discovery of betamethasone 17α-carbamates as dissociated glucocorticoid receptor modulators in the rat

Ali, Amjad ; Balkovec, James M ; Greenlee, Mark ; Hammond, Milton L ; Rouen, Greg ; Taylor, Gayle ; Einstein, Monica ; Ge, Lan ; Harris, Georgianna ; Kelly, Terri M ; Mazur, Paul ; Pandit, Shilpa ; Santoro, Joseph ; Sitlani, Ayesha ; Wang, Chuanlin ; Williamson, Joann ; Forrest, Michael J ; Carballo-Jane, Ester ; Luell, Silvi ; Lowitz, Karen

Bioorganic & Medicinal Chemistry, 2008, Vol.16(16), pp.7535-7542 [Peer Reviewed Journal]

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20
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Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators

Kim, Seongkon ; Wu, Jane Y ; Birzin, Elizabeth T ; Frisch, Katalin ; Chan, Wanda ; Pai, Lee-Yuh ; Yang, Yi Tien ; Mosley, Ralph T ; Fitzgerald, Paula M D ; Sharma, Nandini ; Dahllund, Johanna ; Thorsell, Ann-Gerd ; Dininno, Frank ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Journal of medicinal chemistry, 22 April 2004, Vol.47(9), pp.2171-5 [Peer Reviewed Journal]

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21
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Novel N-arylpyrazolo3,2-c-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity

Ali, Amjad ; Thompson, Christopher F ; Balkovec, James M ; Graham, Donald W ; Hammond, Milton L ; Quraishi, Nazia ; Tata, James R ; Einstein, Monica ; Ge, Lan ; Harris, Georgianna ; Kelly, Terri M ; Mazur, Paul ; Pandit, Shilpa ; Santoro, Joseph ; Sitlani, Ayesha ; Wang, Chuanlin ; Williamson, Joanne ; Miller, Douglas K ; Thompson, Chris M ; Zaller

Journal of medicinal chemistry, 06 May 2004, Vol.47(10), pp.2441-52 [Peer Reviewed Journal]

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22
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Total synthesis of 1-156,602, a novel cyclic hexadepsipeptide antibiotic

Durette, Philippe L ; Baker, Florence ; Barker, Peter L ; Boger, Joshua ; Bondy, Steven S ; Hammond, Milton L ; Lanza, Thomas J ; Pessolano, Arsenio A ; Caldwell, Charles G

Tetrahedron Letters, 1990, Vol.31(9), pp.1237-1240 [Peer Reviewed Journal]

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23
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The mass spectra of suprasterol 3-II, vitamin D 3 and related molecules

Okamura, William H ; Hammond, Milton L ; Jacobs, Harry J.C ; Thuijl, Jan van

Tetrahedron Letters, 1976, Vol.17(52), pp.4807-4810 [Peer Reviewed Journal]

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24
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Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate

Shen, Hong C ; Ding, Fa-Xiang ; Raghavan, Subharekha ; Deng, Qiaolin ; Luell, Silvi ; Forrest, Michael J ; Carballo-Jane, Ester ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Wu, Kenneth K ; Wu, Tsuei-Ju ; Cheng, Kang ; Ren, Ning ; Cai, Tian-Quan ; Chen, Qing ; Wang, Junying ; Wolff, Michael S ; Tong, Xinchun ; Holt

Journal of medicinal chemistry, 25 March 2010, Vol.53(6), pp.2666-70 [Peer Reviewed Journal]

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25
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Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A

Shen, Hong C ; Taggart, Andrew K.P ; Wilsie, Larissa C ; Waters, M. Gerard ; Hammond, Milton L ; Tata, James R ; Colletti, Steven L

Bioorganic & Medicinal Chemistry Letters, 2008, Vol.18(18), pp.4948-4951 [Peer Reviewed Journal]

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Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor

Shen, Hong C ; Ding, Fa-Xiang ; Luell, Silvi ; Forrest, Michael J ; Carballo-Jane, Ester ; Wu, Kenneth K ; Wu, Tsuei-Ju ; Cheng, Kang ; Wilsie, Larissa C ; Krsmanovic, Mihajlo L ; Taggart, Andrew K ; Ren, Ning ; Cai, Tian-Quan ; Deng, Qiaolin ; Chen, Qing ; Wang, Junying ; Wolff, Michael S ; Tong, Xinchun ; Holt, Tom G ; Waters

Journal of medicinal chemistry, 13 December 2007, Vol.50(25), pp.6303-6 [Peer Reviewed Journal]

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27
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Tetrahydrofluorenones with conformationally restricted side chains as selective estrogen receptor beta ligands

Wildonger, Kenneth J ; Ratcliffe, Ronald W ; Mosley, Ralph T ; Hammond, Milton L ; Birzin, Elizabeth T ; Rohrer, Susan P

Bioorganic & Medicinal Chemistry Letters, 2006, Vol.16(17), pp.4462-4466 [Peer Reviewed Journal]

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28
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Comparison of 2-phenylspiroindenes and 2-phenylspiroindenediones as estrogen receptor ligands--modeling and binding data don't agree!

Blizzard, Timothy A ; Mosley, Ralph T ; Birzin, Elizabeth T ; Chan, Wanda ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 08 March 2004, Vol.14(5), pp.1317-21 [Peer Reviewed Journal]

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29
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6H-Benzo[c]chromen-6-one derivatives as selective ERβ agonists

Sun, Wanying ; Cama, Lovji D ; Birzin, Elizabeth T ; Warrier, Sudha ; Locco, Louis ; Mosley, Ralph ; Hammond, Milton L ; Rohrer, Susan P

Bioorganic & Medicinal Chemistry Letters, 15 March 2006, Vol.16(6), pp.1468-1472 [Peer Reviewed Journal]

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2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs)

Blizzard, Timothy A ; Morgan, II, Jerry D ; Mosley, Ralph T ; Birzin, Elizabeth T ; Frisch, Katalin ; Rohrer, Susan P ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2003, Vol.13(3), pp.479-483 [Peer Reviewed Journal]

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31
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Antibacterial activity of G6-quaternary ammonium derivatives of a lipophilic vancomycin analogue

Blizzard, Timothy A ; Kim, Ronald M ; Morgan, Jerry D ; Chang, Jiang ; Kohler, Joyce ; Kilburn, Ruth ; Chapman, Kevin ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 25 March 2002, Vol.12(6), pp.849-52 [Peer Reviewed Journal]

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32
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Synthesis and biological evaluation of platensimycin analogs

Shen, Hong C ; Ding, Fa-Xiang ; Singh, Sheo B ; Parthasarathy, Gopalakrishnan ; Soisson, Stephen M ; Ha, Sookhee N ; Chen, Xun ; Kodali, Srinivas ; Wang, Jun ; Dorso, Karen ; Tata, James R ; Hammond, Milton L ; Maccoss, Malcolm ; Colletti, Steven L

Bioorganic & medicinal chemistry letters, 15 March 2009, Vol.19(6), pp.1623-7 [Peer Reviewed Journal]

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33
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Bridged androstenediol analogs as ER-β selective SERMs

Blizzard, Timothy A ; Gude, Candido ; Chan, Wanda ; Birzin, Elizabeth T ; Mojena, Marina ; Tudela, Consuelo ; Chen, Fang ; Knecht, Kristin ; Su, Qin ; Kraker, Bryan ; Holmes, Mark A ; Rohrer, Susan P ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2007, Vol.17(10), pp.2944-2948 [Peer Reviewed Journal]

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Estrogen receptor ligands. Part 14: Application of novel antagonist side chains to existing platforms

Blizzard, Timothy A ; Morgan, Jerry D ; Chan, Wanda ; Birzin, Elizabeth T ; Pai, Lee-Yuh ; Hayes, Edward C ; Dasilva, Carolyn A ; Mosley, Ralph T ; Yang, Yi Tien ; Rohrer, Susan P ; Dininno, Frank ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(23), pp.5124-5128 [Peer Reviewed Journal]

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Estrogen receptor ligands. Part 11: Synthesis and activity of isochromans and isothiochromans

Liu, Jian ; Birzin, Elizabeth T ; Chan, Wanda ; Yang, Yi Tien ; Pai, Lee-Yuh ; Dasilva, Carolyn ; Hayes, Edward C ; Mosley, Ralph T ; Dininno, Frank ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Bioorganic & Medicinal Chemistry Letters, 2005, Vol.15(3), pp.715-718 [Peer Reviewed Journal]

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Estrogen receptor ligands. Part 6: Synthesis and binding affinity of dihydrobenzodithiins

Tan, Qiang ; Birzin, Elizabeth T ; Chan, Wanda ; Yang, Yi Tien ; Pai, Lee-Yuh ; Hayes, Edward C ; Dasilva, Carolyn A ; Dininno, Frank ; Rohrer, Susan P ; Schaeffer, James M ; Hammond, Milton L

Bioorganic & medicinal chemistry letters, 16 July 2004, Vol.14(14), pp.3753-5 [Peer Reviewed Journal]

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